Tseba hore na hormone ea ACTH e phahameng kapa e tlase e bolelang

Litaba

• Ho ka etsahala liphetoho ho ACTH
• Phahameng ACTH
• Tlaase ACTH
• Litlhahiso bakeng sa tlhatlhobo

Hormone ea adrenocorticotropic, e tsejoang hape e le corticotrophin le khutsufatso ea ACTH, e hlahisoa ke tšoelesa ea pituitary mme e sebeletsa haholoholo ho lekola mathata a amanang le litšoelesa tsa pituitary le adrenal. Kahoo, litekanyo tsa ACTH li bohlokoa ho khetholla maemo a kang Cushing's syndrome, lefu la Addison, lefu la ectopic secretion, kankere ea matšoafo le qoqotho le ho hloleha ha tšoelesa ea adrenal, mohlala.

Tlhatlhobo ea ACTH hangata e kopuoa ke ngaka hammoho le tekanyo ea cortisol e le hore kamano lipakeng tsa lihormone tsena tse peli e ka hlahlojoa, kaha ACTH e hlohlelletsa tlhahiso ea cortisol. Boleng bo tloaelehileng ba ACTH maling bo ka fihla ho 46 pg / mL, e ka fapana ho latela laboratori eo teko e etsoang ho eona le nako ea pokello, kaha maemo a hormone ena a fapana ho pholletsa le letsatsi, mme pokello e khothaletsoa hoseng.

Theko ea tlhatlhobo ea ACTH e fapana pakeng tsa R $ 38 le R $ 50.00 ho latela laboratori, leha ho le joalo, e etsoa hore e fumanehe ke SUS.

Ho ka etsahala liphetoho ho ACTH

ACTH e patoa butle-butle motšehare, e nang le maemo a holimo ho 6 le 8 hoseng le maemong a tlase ka 9 pm le 10 pm. Tlhahiso ea hormone ena e eketseha haholo maemong a sithabetsang, a hlohlelletsang tlhahiso ea cortisol, e ikarabellang ho laoleng khatello ea maikutlo, ho tšoenyeha le ho ruruha. Ithute haholoanyane ka cortisol le hore na ke ea eng.

Liphetoho tse ka bang teng ho ACTH e ka ba:

Phahameng ACTH

• Cushing's syndrome, e ka lebisang tlhahisong e eketsehileng ea ACTH ke tšoelesa ea pituitary;
• Ho haella ha adrenal ea mantlha;
• Adrenogenital syndrome e nang le tlhahiso e fokotsehileng ea cortisol;
• Ts'ebeliso ea amphetamine, insulin, levodopa, metoclopramide le mifepristone.

Ho phahama haholo ha ACTH maling ho ka eketsa ho senyeha ha lipids, ho eketsa mohopolo oa mafura a acids le glycerol maling, ho hlasimolla sephiri sa insulin le ho eketsa tlhahiso ea kholo ea hormone, GH. Utloisisa hore na GH ke eng le hore na e etselitsoe eng.

Tlaase ACTH

• Hypopituitarism;
• Ho se sebetse hoa pituitary ea ACTH - adrenal ea bobeli;
• Ts'ebeliso ea corticosteroids, estrogens, spironolactone, amphetamine, joala, lithium, bokhachane, nako ea ho ilela khoeli, boikoetliso.

Teko e laeloa ke ngaka ha motho a e-na le matšoao a amanang le keketseho kapa ho fokotseha ha cortisol maling. Matšoao a ka supang cortisol e phahameng a na le boima bo feteletseng ba mmele, letlalo le lesesane, 'mala o bofubelu bo otlolohileng mpeng, makhopho, ho eketseha ha moriri' meleng le matšoao a ka supang cortisol e tlase ke bofokoli, mokhathala, ho theola boima ba 'mele, ho fifala ha letlalo le ho hloka takatso ea lijo.

Litlhahiso bakeng sa tlhatlhobo

Ho etsa tlhahlobo, ho kgothaletswa hore motho a itime lijo bonyane lihora tse 8 kapa ho latela boeletsi ba bongaka le hore pokello e etsoe hoseng, haholo-holo lihora tse 2 kamora hore motho a tsohe.

Ntle le moo, ho bohlokoa hape hore re se ikoetlise ka letsatsi la tlhatlhobo kapa letsatsi le fetileng le ho fokotsa ts'ebeliso ea lik'habohaedreite tse kang bohobe, raese, litapole le bijoule lihora tse 48 pele ho tlhahlobo, kaha hormone ena e sebetsa taolo ea liprotheine, tsoekere le metabolism ea lipid.