Sengoli: Roger Morrison
Letsatsi La Creation: 28 September 2021
Ntlafatsa Letsatsi: 16 December 2024
Anonim
Methotrexate e etsetsoa eng? - Bophelo
Methotrexate e etsetsoa eng? - Bophelo

Litaba

Letlapa la Methotrexate ke pheko e bonts'itsoeng bakeng sa kalafo ea ramatiki ea ramatiki le psoriasis e matla e sa arabeleng kalafo tse ling. Ho feta moo, methotrexate e boetse e fumaneha e le ente, e sebelisoang ho chemotherapy bakeng sa kalafo ea mofetše.

Pheko ena e fumaneha ka sebopeho sa pilisi kapa ente mme e ka fumanoa li-pharmacy tlasa mabitso a Tecnomet, Enbrel le Endofolin.

E etselitsoe eng

Methotrexate matlapeng e bontšoa bakeng sa kalafo ea ramatiki ea lefu la masapo, kaha e na le litlamorao tsamaisong ea 'mele ea ho itšireletsa mafung, ho fokotsa ho ruruha, ketso ea eona e hlokomeloa ho tloha bekeng ea boraro ea kalafo.Ha ho phekoloa psoriasis, methotrexate e fokotsa ho ata le ho ruruha ha lisele tsa letlalo mme litlamorao tsa eona li hlokomeloa libeke tse 1 ho isa ho tse 4 kamora ho qala kalafo.


Methotrexate e nang le ente e bontšoa ho phekola psoriasis e matla le mefuta e latelang ea mofets'e:

  • Li-neoplasms tsa bokhachane;
  • Li-leukemias tse nang le lymphocytic;
  • Kankere e nyenyane ea matšoafo ea sele;
  • Kankere ea hlooho le molala;
  • Kankere ea matsoele;
  • Osteosarcoma;
  • Kalafo le prophylaxis ea lymphoma kapa meningeal leukemia;
  • Palliative therapy bakeng sa lihlahala tse tiileng tse sa sebetseng;
  • Lymphomas eo e seng ea Hodgkin le Burkitt's lymphoma.

Mokhoa oa ho sebelisa

1. Ramatiki ea ramatiki

Tekanyo e khothalletsoang ea molomo e ka ba 7.5 mg, hang ka beke kapa 2.5 mg, lihora tse ling le tse ling tsa 12, bakeng sa litekanyetso tse tharo, tse tsamaisoang joalo ka potoloho, hang ka beke.

Litekanyo tsa mofuta o mong le o mong li lokela ho fetoloa hanyane ka hanyane ho fihlela karabelo e nepahetseng, empa ha lia lokela ho feta tekanyetso ea beke le beke ea 20 mg.

2. Psoriasis

Tekanyo e khothalletsoang ea molomo ke 10 - 25 mg ka beke, ho fihlela karabelo e lekaneng e fihletsoe kapa, ho seng joalo, 2.5 mg, lihora tse ling le tse ling tse 12, bakeng sa litekanyetso tse tharo.


Litekanyo tsa mofuta o mong le o mong li ka fetoloa hanyane ka hanyane ho fihlela karabelo e nepahetseng ea kliniki, ho qoba ho feta lethal dose ea 30 mg ka beke.

Bakeng sa linyeoe tsa psoriasis e matla, moo methotrexate e nang le ente e sebelisoang, ho lokela ho fanoa ka tekanyetso e le 'ngoe ea 10 ho isa ho 25 mg ka beke ho fihlela ho fumanoa karabelo e lekaneng. Ithute ho khetholla matšoao a psoriasis le tlhokomelo eo u lokelang ho e nka.

3. Kankere

Mefuta ea kalafo ea methotrexate bakeng sa matšoao a kankere e pharalletse haholo, ho latela mofuta oa mofetše, boima ba 'mele le maemo a mokuli.

Litla-morao tse ka bang teng

Litla-morao tse atisang ho hlaha nakong ea kalafo ka lipilisi tsa methotrexate ke ho opeloa ke hlooho e bohloko, ho satalla molala, ho hlatsa, feberu, bofubelu ba letlalo, ho eketsa acid ea uric le phokotso ea palo ea peo ea botona, ponahalo ea liso tsa molomo, ho ruruha ha leleme. marenene, letšollo, phokotso ea lisele tse tšoeu tsa mali le palo ea li-platelet, ho hloleha ha liphio le pharyngitis.


Ke mang ea sa lokelang ho sebelisa

Letlapa la Methotrexate ha le lumellane le bakuli ba nang le alejiki ea methotrexate kapa karolo efe kapa efe ea popo, basali ba baimana, basali ba anyesang, batho ba nang le boits'ireletso ba mmele bo fokolisitsoeng, sebete se matla kapa liphio ho se sebetse hantle le liphetoho liseleng tsa mali joalo ka ho fokotsoa ha lisele tsa mali ho bala lisele tse tšoeu tsa mali, bofubelu lisele tsa mali le liplatelete.

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