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Prolactin ke hormone e hlahisoang ke tšoelesa ea pituitary. Teko ea prolactin e lekanya palo ea prolactin maling.

Ho hlokahala sampole ea mali.

Ha ho litokisetso tse khethehileng tse hlokahalang.

Ha nale e kentsoe ho hula mali, batho ba bang ba utloa bohloko bo itekanetseng. Ba bang ba ikutloa feela ho hlaba kapa ho hlaba. Kamora moo, ho ka ba le ho phatloha kapa ho longoa hanyane. Haufinyane sena sea fela.

Prolactin ke hormone e hlahisoang ke tšoelesa ea pituitary. Pituitary ke tšoelesa e nyane botlaaseng ba boko. E laola botsitso ba 'mele ba lihomone tse ngata.

Prolactin e hlohlelletsa nts'etsopele ea matsoele le tlhahiso ea lebese ho basali. Ha ho na ts'ebetso e tloaelehileng e tsebahalang ea prolactin ho banna.

Prolactin hangata e lekanyetsoa ha ho hlahlojoa lihlahala tsa pituitary le sesosa sa:

  • Tlhahiso ea lebese la lebese e sa amaneng le ho beleha (galactorrhea)
  • Ho fokotsa thobalano (libido) ho banna le basali
  • Mathata a ho emisa ho banna
  • Ha a khone ho ima (ho hloka thari)
  • Nako e sa tloaelehang kapa e seng ea ho ilela khoeli (amenorrhea)

Litekanyetso tse tloaelehileng tsa prolactin ke:


  • Banna: ka tlase ho 20 ng / mL (425 µg / L)
  • Basali ba sa imeng: ka tlase ho 25 ng / mL (25 µg / L)
  • Bakhachane: 80 ho isa ho 400 ng / mL (80 ho isa ho 400 µg / L)

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Li-lab tse ling li sebelisa litekanyo tse fapaneng kapa li leka liteko tse fapaneng. Bua le ngaka ea hau ka se boleloang ke sephetho sa hau sa liteko.

Batho ba nang le maemo a latelang ba ka ba le maemo a phahameng a prolactin:

  • Kotsi ea lebota la sefubeng kapa ho teneha
  • Boloetse ba sebaka sa boko bo bitsoang hypothalamus
  • Tšoelesa ea qoqotho ha e etse hormone ea qoqotho e lekaneng (hypothyroidism)
  • Lefu la liphio
  • Hlahala ea pituitary e etsang prolactin (prolactinoma)
  • Lihlahala le mafu a mang a pituitary a sebakeng sa pituitary
  • Tloso e sa tloaelehang ea limolek'hule tsa prolactin (macroprolactin)

Meriana e meng e ka phahamisa boemo ba prolactin, ho kenyelletsa:

  • Ho imeloa kelellong
  • Butyrophenones
  • Estrogens
  • Li-block tsa H2
  • Methyldopa
  • Metoclopramide
  • Meriana Opiate
  • Li-phenothiazine
  • Tsosa maikutlo
  • Risperidone
  • Litlhare

Lihlahisoa tsa matekoane le tsona li ka nyolla boemo ba prolactin.


Haeba boemo ba hau ba prolactin bo phahame, tlhahlobo e ka phetoa hoseng haholo kamora ho itima lijo ha lihora tse 8.

Tse latelang li ka eketsa maemo a prolactin ka nakoana:

  • Khatello ea maikutlo kapa ea 'mele (ka linako tse ling)
  • Lijo tse nang le protheine e phahameng
  • Tšusumetso e matla ea matsoele
  • Tlhahlobo ea morao-rao ea matsoele
  • Boikoetliso ba morao-rao

Tlhaloso ea tlhahlobo e phahameng ea mali e phahameng ka mokhoa o sa tloaelehang e thata. Maemong a mangata, mofani oa hau o tla hloka ho u fetisetsa ho endocrinologist, ngaka e sebetsanang le mathata a lihormone.

Ho na le kotsi e nyane ea ho nkuoa mali a hau. Methapo le methapo li fapana ka boholo ho tloha ho motho e mong ho ea ho o mong le ho tloha lehlakoreng le leng la 'mele ho ea ho le leng. Ho nka mali ho batho ba bang ho ka ba thata ho feta ho ba bang.

Likotsi tse ling tse amanang le ho huloa mali li nyane empa li ka kenyelletsa:

  • Ho tsoa mali a mangata
  • Li-punctures tse ngata ho fumana methapo
  • Ho akheha kapa ho ikutloa o le hlooho e boima
  • Hematoma (mali a hahiloeng ka tlas'a letlalo)
  • Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

PRL; Galactorrhea - tlhahlobo ea prolactin; Ho hloka thari - teko ea prolactin; Amenorrhea - tlhahlobo ea prolactin; Ho tsoa ha matsoele - teko ea prolactin; Prolactinoma - teko ea prolactin; Teko ea pituitary - prolactin test


CC ea Chernecky, Berger BJ. Prolactin (prolactin ea motho, HPRL) - serum. Ka: Chernecky CC, Berger BJ, bahlophisi. Liteko tsa Laboraro le Mekhoa ea Tlhatlhobo. La 6th. Philadelphia, PA: Elsevier Saunders; 2013: 910-911.

Guber HA, Farag AF. Tlhatlhobo ea ts'ebetso ea endocrine. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. St Louis, MO: Elsevier; 2017: khaolo ea 24.

Kaiser U, Ho K. Pituitary physiology le tlhahlobo ea tlhahlobo. Ka: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, bahlophisi. Buka ea Williams ea Endocrinology. La bo14 la ed. Philadelphia, PA: Elsevier; 2020: khaolo ea 8.

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