Na Glucosamine ea sebetsa? Melemo, Tekanyo le Litlamorao

Litaba

• Glucosamine ke eng?
• E ka Fokotsa Ho Ruruha
• Tshehetsa Healthy manonyeletso
• Hangata e sebelisetsoang ho phekola mathata a masapo le manonyeletso
• Mekhoa e meng ea Glucosamine
• Cystitis e kenang
• Lefu la ho ruruha ha 'mele (IBD)
• Multiple Sclerosis (MS)
• Glaucoma
• Kopanelo ea Temporomandibular (TMJ)
• Na ehlile ea sebetsa?
• Tekanyo le Liforomo tsa Tlatsetso
• Likotsi tse ka bang teng le litlamorao
• Ntlha ea Bohlokoa

Glucosamine ke molek'hule e hlahang ka tlhaho 'meleng oa hau, empa hape ke tlatsetso e tsebahalang ea lijo.

Hangata e sebelisetsoang ho phekola matšoao a lefu la masapo le manonyeletso, e sebelisoa ka mokhoa o ts'oanang ho supa mafu a mang a mangata a hlabang.

Sengoloa sena se hlahloba melemo ea li-glucosamine, litekanyetso le litla-morao.

Glucosamine ke eng?

Glucosamine ke motsoako oa tlhaho o hlahang ka lik'hemik'hale e le tsoekere ea amino (1).

E sebetsa e le moaho oa limolek'hule tse fapaneng tse sebetsang 'meleng oa hau empa e tsejoa haholo bakeng sa ho nts'etsapele le ho boloka lefufuru ka har'a manonyeletso a hau (1).

Glucosamine e boetse e fumaneha liphoofolong tse ling le liphoofolong tse ling tseo e seng batho, ho kenyeletsoa likhetla tsa likhetla, masapo a liphoofolo le li-fungus. Mefuta e tlatselletsang ea glucosamine hangata e etsoa ka mehloli ena ea tlhaho (2).

Glucosamine e sebelisoa khafetsa ho phekola le ho thibela mathata a kopaneng, joalo ka osteoarthritis. E ka nkoa ka molomo kapa ea sebelisoa ka har'a lihlooho ka tranelate kapa letsoai (2).

Glucosamine ke motsoako oa lik'hemik'hale o hlahang ka tlhaho meleng ea batho le ea liphoofolo. Ho batho, e thusa ho theha lefufuru mme e sebelisoa khafetsa e le tlatsetso ea phepo ho phekola mathata a kopaneng joalo ka osteoarthritis.

E ka Fokotsa Ho Ruruha

Glucosamine e sebelisoa khafetsa ho alafa matšoao a maemo a fapaneng a ho ruruha.

Le ha mekhoa ea glucosamine e ntse e sa utloisisoe hantle, ho bonahala e fokotsa habonolo ho ruruha.

Phuputso e 'ngoe e entsoeng ka "tube" ea liteko e bonts'itse tšusumetso e matla e khahlano le ho ruruha ha glucosamine e ne e sebelisoa liseleng tse amehang masapong a masapo ().

Boholo ba lipatlisiso tsa glucosamine li kenyelletsa ka nako e le 'ngoe ho tlatsetsa le chondroitin - komporo e ts'oanang le glucosamine, eo hape e amehang tlhahisong ea' mele oa hau le tlhokomelong ea lefufuru (4).

Phuputso ho batho ba fetang 200 e hokahantsoeng le li-supplements tsa glucosamine ho fokotsa 28% le 24% ho likarolo tse peli tsa biochemical tsa ho ruruha: CRP le PGE. Leha ho le joalo, liphetho tsena e ne e se tsa bohlokoa lipalo ().

Ke habohlokoa ho hlokomela hore thuto e tšoanang e fumane ho fokotseha ha 36% ea matšoao ana a ho ruruha bakeng sa batho ba nkang chondroitin. Sephetho sena e ne e le sa bohlokoa ().

Liphuputso tse ling li eketsa liphuputso tse joalo. Hopola hore barupeluoa ba bangata ba nkang chondroitin le bona ba tlaleha ka nako e le 'ngoe ho tlatselletsa le glucosamine.

Kahoo, ho ntse ho sa hlaka hore na liphetho li tsamaisoa ke chondroitin feela kapa motsoako oa litlatsetso ka bobeli tse nkuoeng hammoho ().

Qetellong, ho hlokahala lipatlisiso tse ngata mabapi le karolo ea glucosamine phokotsong ea matšoao a ho ruruha 'meleng oa hau.

Tsela eo glucosamine e sebetsang kalafong ea mafu ha e utloisisoe hantle, empa lipatlisiso tse ling li bonts'a hore e ka fokotsa ho ruruha - haholo ha e sebelisoa le li-supplement tsa chondroitin.

Tshehetsa Healthy manonyeletso

Glucosamine e teng ka tlhaho 'meleng oa hau. O mong oa mesebetsi ea ona ea mantlha ke ho ts'ehetsa kholo e phetseng hantle ea lisele tse pakeng tsa manonyeletso a hau (1).

Articular cartilage ke mofuta oa lisele tse tšoeu tse boreleli tse koahelang lipheletsong tsa masapo a hau moo li kopanang teng ho etsa manonyeletso.

Mofuta ona oa lisele - hammoho le mokelikeli o tlotsang o bitsoang synovial fluid - o lumella masapo ho tsamaea ka bolokolohi, ho fokotsa khohlano le ho lumella motsamao o se nang bohloko manonyellong a hau.

Glucosamine e thusa ho theha metsoako e mengata ea lik'hemik'hale e amehang ho thehoeng ha lefufuru la methapo le synovial fluid.

Liphuputso tse ling li bonts'a hore tlatsetso ea glucosamine e ka sireletsa lisele tse kopaneng ka ho thibela ho senyeha ha lefufuru.

Phuputso e 'ngoe e nyane ho bapalami ba libaesekele ba 41 e fumane hore ho tlatselletsa ka ligrama tse 3 tsa glucosamine letsatsi le leng le le leng ho fokotsa ho senyeha ha collagen mangoleng ka 27% ha ho bapisoa le 8% sehlopheng sa placebo ().

Phuputso e 'ngoe e nyane e fumane karolelano e fokotsehileng haholo ea "collagen-breakdown" ho "collagen-synthesis markers" manonyeletsong a libapali tsa bolo ea maoto a alafshoang ka ligrama tse 3 tsa glucosamine ka letsatsi nakong ea likhoeli tse tharo ().

Liphetho tsena li fana ka maikutlo a ts'ireletso e kopaneng ea glucosamine. Leha ho le joalo, lipatlisiso tse ling lia hlokahala.

Glucosamine e kenya letsoho ho nts'etsopele lisele tse bohlokoa bakeng sa tšebetso e nepahetseng ea kopanelo. Le ha lithuto tse ling li hlokahala, lipatlisiso tse ling li bonts'a hore tlatsetso ea glucosamine e ka sireletsa manonyeletso a hau tšenyo.

Hangata e sebelisetsoang ho phekola mathata a masapo le manonyeletso

Hangata li-supplements tsa Glucosamine li nkoa ho phekola maemo a fapaneng a masapo le manonyeletso.

Molek'hule ena e ithutiloe ka kotloloho bakeng sa bokhoni ba eona ba ho phekola matšoao le tsoelo-pele ea mafu e amanang le osteoarthritis, ramatiki ea ramatiki le lefu la masapo.

Liphuputso tse ngata li bonts'a hore ho tlatselletsa letsatsi le letsatsi ka glucosamine sulfate ho ka fana ka kalafo e sebetsang, ea nako e telele ea lefu la masapo ka ho fana ka phokotso e kholo ea bohloko, ho boloka sebaka se kopaneng le ho fokotsa butle-butle mafu a tsoelang pele (,, 10, 11).

Liphuputso tse ling li senotse matšoao a fokotsang haholo a ramatiki ea mafu (RA) ho litoeba tse tšoaroang ka mefuta e fapaneng ea glucosamine (,).

Ka lehlakoreng le leng, phuputso e le 'ngoe ea motho ha ea ka ea bontša liphetoho tse kholo ntlafatsong ea RA ka ts'ebeliso ea glucosamine. Leha ho le joalo, barupeluoa ba ithutoang ba tlalehile taolo ea matšoao e ntlafalitsoeng haholo ().

Liphuputso tse ling tsa pejana litoeba tse nang le lefu la ho fokola ha masapo le tsona li bonts'a monyetla oa tšebeliso ea tlatsetso ea glucosamine ho ntlafatsa matla a masapo ().

Le ha liphetho tsena li khothatsa, ho hlokahala lipatlisiso tse ngata tsa batho ho utloisisa mekhoa ea ts'ebeliso ea glucosamine ho mafu a manonyeletso le masapo.

Le ha glucosamine e sebelisoa khafetsa ho phekola maemo a fapaneng a masapo le manonyeletso, lipatlisiso tse ling ka litlamorao li hlokahala.

Mekhoa e meng ea Glucosamine

Le ha batho ba sebelisa glucosamine ho phekola maloetse a sa foleng a sa foleng, tlhaiso-leseling e felletseng.

Cystitis e kenang

Glucosamine e khothalletsoa hohle joalo ka kalafo ea cystitis (IC), boemo bo amanang le khaello ea komponeng glycosaminoglycan.

Hobane glucosamine ke selelekela sa setsi sena, ho boleloa hore li-supplements tsa glucosamine li ka thusa ho tsamaisa IC ().

Ka bomalimabe, tlhaiso-leseling e tšepahalang ea mahlale e tšehetsang khopolo ena ea haella.

Lefu la ho ruruha ha 'mele (IBD)

Joalo ka cystitis e kenang kahare, lefu la ho ruruha hoa mala (IBD) le amahanngoa le khaello ea glycosaminoglycan ().

Phuputso e fokolang haholo e ts'ehetsa mohopolo oa hore glucosamine e ka alafa IBD. Leha ho le joalo, phuputso e entsoeng ka litoeba le IBD e bontšitse hore ho tlatselletsa ka glucosamine ho ka fokotsa ho ruruha ().

Qetellong, ho hlokahala lipatlisiso tse ngata ho fihlela liqeto tse hlakileng.

Multiple Sclerosis (MS)

Mehloli e meng e re glucosamine e ka ba kalafo e sebetsang bakeng sa multiple sclerosis (MS). Leha ho le joalo, lipatlisiso tse tšehetsang lia haella.

Phuputso e 'ngoe e hlahlobile phello ea ho sebelisa glucosamine sulphate hammoho le kalafo ea setso bakeng sa ho khutlisa hape ka MS. Liphetho ha li bontše phello e kholo ho sekhahla sa ho khutlela morao kapa kholo ea mafu ka lebaka la glucosamine ().

Glaucoma

Glaucoma ho lumeloa hore e ka phekoloa ka glucosamine.

Liphuputso tse ling tsa pejana li bonts'a hore glucosamine sulfate e ka khothaletsa bophelo bo botle ba mahlo ka ho fokotsa ho ruruha le litlamorao tsa antioxidant ho retina ea hau.

Ka lehlakoreng le leng, phuputso e 'ngoe e nyane e bonts'itse hore ho ja haholo ha glucosamine ho ka lematsa batho ba nang le glaucoma ().

Ka kakaretso, data ea hajoale ha e tsejoe.

Kopanelo ea Temporomandibular (TMJ)

Mehloli e meng e re glucosamine ke kalafo e sebetsang bakeng sa TMJ, kapa lenonyello la temporomandibular. Leha ho le joalo, lipatlisiso tse tšehetsang tseko ena ha lia lekana.

Phuputso e le 'ngoe e nyane e bonts'itse phokotso e kholo ea mahlaba le matšoao a ho ruruha, hammoho le ho eketseha ha mohlahare ho bankakarolo ba fumaneng tlatsetso e kopaneng ea glucosamine sulfate le chondroitin ().

Phuputso e 'ngoe e nyane ha ea ka ea hlahisa litlamorao tsa nako e khuts'oane tsa li-supplement tsa glucosamine hydrochloride bakeng sa batho ba nang le TMJ. Leha ho le joalo, ntlafatso e kholo ea taolo ea bohloko ba nako e telele e tlalehiloe ().

Liphetho tsena tsa boithuto lia ts'episa empa ha li fane ka data e lekaneng ho ts'ehetsa liqeto tse hlakileng. Ho hlokahala lipatlisiso tse ling.

Le ha glucosamine hangata e nkuoa e le kalafo e sebetsang bakeng sa maemo a fapaneng, ha ho na lintlha tse hlakileng mabapi le ts'usumetso ea eona.

Na ehlile ea sebetsa?

Le ha ho etsoa lipolelo tse pharaletseng mabapi le litlamorao tse ntle tsa glucosamine ho mafu a mangata, lipatlisiso tse fumanehang li ts'ehetsa ts'ebeliso ea eona bakeng sa maemo a fokolang.

Hajoale, bopaki bo matla ka ho fetisisa bo ts'ehetsa ts'ebeliso ea glucosamine sulfate bakeng sa kalafo ea nako e telele ea matšoao a lefu la masapo. Seo se boletse, se kanna sa se sebetse e mong le e mong ().

Ho ea ka tlhaiso-leseling e fumanehang, ha ho bonolo hore e be kalafo e sebetsang bakeng sa maloetse a mang kapa maemo a ho ruruha.

Haeba u ntse u nahana ho sebelisa glucosamine, hopola boleng ba tlatsetso eo u e khethang - kaha sena se ka etsa phapang hore na se u ama joang.

Linaheng tse ling - ho kenyeletsoa le US - ho na le melaoana e fokolang haholo ea litlatsetso tsa phepo. Ka hona, mabitso a ka thetsa (2).

Kamehla ho molemo ho hlahloba setifikeiti sa motho oa boraro ho netefatsa hore o fumana seo o se lefellang hantle. Baetsi ba ikemiselitseng hore lihlahisoa tsa bona li hlahlojoe hore na li hloekile ke motho oa boraro ba tloaetse ho ba le maemo a holimo.

ConsumerLab, NSF International le US Pharmacopeia (USP) ke likhamphani tse 'maloa tse ikemetseng tse fanang ka lits'ebeletso tsa setifikeiti. Haeba u bona e 'ngoe ea matšoao a bona ho tlatsetso ea hau, mohlomong ke ea boleng bo botle.

Boholo ba lipatlisiso bo tšehetsa ts'ebeliso ea glucosamine-sulfate bakeng sa ho sebetsana le matšoao a lefu la masapo. Ha ho bonolo hore e atlehe lits'ebetsong tse ling.

Tekanyo le Liforomo tsa Tlatsetso

Tekanyo e tloaelehileng ea glucosamine ke 1,500 mg ka letsatsi, eo u ka e nkang hang-hang kapa ka litekanyetso tse nyane tse ngata ho pholletsa le letsatsi (2).

Li-supplement tsa Glucosamine li entsoe ka mehloli ea tlhaho - joalo ka likhetla tsa shellfish kapa li-fungus - kapa li entsoe ka mahahapa ka laborateng.

Lisebelisoa tsa Glucosamine li fumaneha ka mefuta e 'meli (1):

• Glucosamine sulfate
• Glucosamine hydrochloride

Nako le nako, glucosamine sulfate e boetse e rekisoa hammoho le chondroitin sulfate.

Lintlha tse ngata tsa mahlale li bonts'a katleho e kholo bakeng sa glucosamine sulfate kapa glucosamine sulfate e kopaneng le chondroitin.

Glucosamine e tloaetse ho tšeloa ka 1,500 mg ka letsatsi. Ho mefuta e fumanehang, glucosamine sulfate - e nang le chondroitin kapa ntle le eona - e kanna ea sebetsa ka ho fetisisa.

Likotsi tse ka bang teng le litlamorao

Lisebelisoa tsa Glucosamine li kanna tsa bolokeha ho batho ba bangata. Leha ho le joalo, likotsi tse ling li teng.

Likotsi tse ka bang teng li kenyelletsa (1):

• Ho nyekeloa le ho hlatsa
• Letšollo
• Ho heletsa
• Bohloko ba mpeng

Ha ua lokela ho nka glucosamine haeba u imme kapa u anyesa ka lebaka la ho haella ha bopaki bo tšehetsang polokeho ea eona.

Glucosamine e ka mpefatsa taolo ea tsoekere maling ho batho ba nang le lefu la tsoekere, leha kotsi ena e le tlase haholo. Haeba u na le lefu la tsoekere kapa u noa meriana ea lefu la tsoekere, buisana le ngaka pele u nka glucosamine (2).

Glucosamine e kanna ea sireletseha ho batho ba bangata. Ho tlalehiloe ho halefa ho bonolo ha masapo. Haeba u na le lefu la tsoekere, glucosamine e ka mpefatsa taolo ea tsoekere ea mali.

Ntlha ea Bohlokoa

Glucosamine e teng ka tlhaho ka har'a mmele oa hau mme e bapala karolo ea bohlokoa ho nts'etsopele le ho hlokomeleng manonyeletso a phetseng hantle.

Le ha glucosamine e sebelisetsoa ho alafa maloetse a fapaneng a kopaneng, masapo le a ho ruruha, joalo ka IBD, interstitial cystitis le TMJ, lipatlisiso tse ngata li ts'ehetsa katleho ea eona bakeng sa taolo ea matšoao a nako e telele ea lefu la masapo.

E bonahala e bolokehile ho batho ba bangata ka litekanyetso tsa 1,500 mg ka letsatsi empa e ka baka litla-morao tse bobebe.

Haeba u batla phomolo ea lefu la masapo a mabeli, ho nka tlatsetso ea glucosamine ho ka ba molemo ho nahana, empa etsa bonnete ba hore u bua le ngaka pele.