Teko ea mali ea Aldosterone

Teko ea mali ea aldosterone e lekanya boemo ba hormone aldosterone maling.

Aldosterone le eona e ka lekanyetsoa ho sebelisoa tlhahlobo ea moroto.

Ho hlokahala sampole ea mali.

Mofani oa hao oa tlhokomelo ea bophelo a ka u kopa hore u khaotse ho noa meriana e itseng matsatsi a seng makae pele ho tlhahlobo e le hore li se ke tsa ama sephetho sa liteko. Etsa bonnete ba hore o bolella mofani oa hau ka meriana eohle eo u e nkang. Tsena li kenyelletsa:

• Meriana e phahameng ea khatello ea mali
• Meriana ea pelo
• Lithethefatsi tse seng khahlanong le ho ruruha (li-NSAID)
• Meriana ea li-antacid le seso
• Lipilisi tsa metsi (diuretics)

Se ke oa emisa ho noa moriana pele u bua le ngaka ea hau. Mofani oa hau a ka khothaletsa hore o se ke oa ja ligrama tse fetang 3 tsa letsoai (sodium) ka letsatsi bonyane libeke tse 2 pele ho tlhahlobo.

Kapa, ​​mofani oa hau o tla khothaletsa hore o je letsoai la hau le tloaelehileng hape o leke palo ea sodium morotong oa hau.

Ka linako tse ling, tlhahlobo ea mali ea aldosterone e etsoa pele le kamora hore o fumane tharollo ea letsoai (saline) ka methapo (IV) lihora tse 2. Hlokomela hore lintlha tse ling li ka ama litekanyo tsa aldosterone, ho kenyelletsa:

• Boimana
• Lijo tse phahameng kapa tse nang le sodium e tlase
• Lijo tse phahameng kapa tse nang le potasiamo e tlase
• Ho ikoetlisa ka thata
• Khatello ea maikutlo

Ha nale e kentsoe ho hula mali, batho ba bang ba utloa bohloko bo itekanetseng. Ba bang ba utloa feela ho hlaba kapa ho hlaba habohloko. Kamora moo, ho ka ba le ho phatloha kapa ho longoa hanyane. Haufinyane sena sea fela.

Teko ena e laeloa bakeng sa maemo a latelang:

• Mathata a mang a mokelikeli le electrolyte, hangata a tlaase kapa a phahameng a mali a sodium kapa a potasiamo e tlase
• Ho thata ho laola khatello ea mali
• Khatello ea mali e tlase ha u eme (orthostatic hypotension)

Aldosterone ke hormone e hlahisoang ke litšoelesa tsa adrenal. E thusa 'mele ho laola khatello ea mali. Aldosterone e eketsa ts'ebetsong ea sodium le metsi le ho lokolloa ha potasiamo liphio. Ketso ena e phahamisa khatello ea mali.

Teko ea mali ea Aldosterone hangata e kopantsoe le liteko tse ling, joalo ka tlhahlobo ea li-hormone ea renin, ho fumana aldosterone e fetang kapa e sa hlahisoeng haholo.

Maemo a tloaelehileng a fapana:

• Pakeng tsa bana, bacha le batho ba baholo
• Ho latela hore na o ne o eme, o lutse kapa o paqame ha mali a huloa

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Li-lab tse ling li sebelisa litekanyo tse fapaneng kapa li leka liteko tse fapaneng. Bua le mofani oa hau ka moelelo oa sephetho sa hau sa liteko.

Boemo bo phahameng ho feta bo tloaelehileng ba aldosterone bo ka bakoa ke:

• Bartter syndrome (sehlopha sa maemo a sa tloaelehang se amang liphio)
• Litšoelesa tsa Adrenal li ntša hormone ea aldosterone e ngata haholo (hyperaldosteronism ea mantlha - hangata e bakoa ke ho ruruha ha pelo ho adrenal gland)
• Lijo tse nang le sodium e tlase haholo
• Ho nka meriana ea khatello ea mali e bitsoang lirafshoa tsa mineralocorticoid

Boemo bo tlase ho feta bo tloaelehileng ba aldosterone e kanna ea ba ka lebaka la:

• Mathata a tšoelesa ea Adrenal, ho kenyelletsa ho se lokolle aldosterone e lekaneng, le boemo bo bitsoang "insufficiency" ea mantlha ea adrenal (lefu la Addison)
• Lijo tse nang le sodium e phahameng haholo

Ha ho na kotsi e kholo ea ho nkuoa mali a hau. Methapo le methapo li fapana ka boholo ho tloha ho mokuli e mong ho ea ho e mong le ho tloha lehlakoreng le leng la 'mele ho ea ho le leng. Ho nka mali ho batho ba bang ho ka ba thata ho feta ho ba bang.

Likotsi tse ling tse amanang le ho huloa mali li nyane empa li ka kenyelletsa:

• Ho tsoa mali a mangata
• Ho akheha kapa ho ikutloa o le hlooho e boima
• Li-punctures tse ngata ho fumana methapo
• Hematoma (mali a bokellanang ka tlasa letlalo)
• Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

Aldosterone - serum; Addison lefu - serum aldosterone; Mathomo hyperaldosteronism - serum aldosterone; Bartter syndrome - serum aldosterone

Tlhokomelo RM, Padia SH. Mathata a mantlha a mineralocorticoid le khatello e phahameng ea mali. Ka: Jameson JL, De Groot LJ, oa Kretser DM, et al, eds. Endocrinology: Batho ba baholo le bana. La 7th. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 108.

Guber HA, Farag AF. Tlhatlhobo ea ts'ebetso ea endocrine. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. St Louis, MO: Elsevier; 2017: khaolo ea 24.