Immunofixation - moroto

Urine immunofixation ke teko ea ho batla liprotheine tse sa tloaelehang morong.

U tla hloka ho fana ka sampole ea ho ntša metsi a hloekileng.

• Hloekisa sebaka se potileng moo moroto o tlohang 'meleng. Banna kapa bashanyana ba lokela ho hlakola hlooho ea botona. Basali kapa banana ba lokela ho hlatsoa sebaka se lipakeng tsa molomo oa mosali ka metsi a sesepa le ho hlatsoa hantle.
• Lumella chelete e nyane hore e oele ka sekotlolo sa ntloana ha u qala ho ntša metsi. Sena se hlakola lintho tse ka silafatsang sampole. Tšoara moroto o ka bang lilithara tse 30 ho isa ho tse 60 ka hara setshelo se hloekileng seo u se fuoeng.
• Tlosa setshelo molatsoaneng oa moroto.
• Fana ka setshelo ho mofani oa tlhokomelo ea bophelo kapa mothusi.

Bakeng sa lesea:

• Hlatsoa ka botlalo sebaka seo moroto o tsoang 'meleng ho sona.
• Bula mokotla oa pokello ea moroto (mokotla oa polasetiki o nang le pampiri e khomarelang ka lehlakoreng le leng).
• Bakeng sa banna, kenya botona kaofela ka mokotleng ebe u hokela sekhomaretsi letlalong.
• Bakeng sa basali, beha mokotla holim'a li-labia.
• Lepa ka mokhoa o tloaelehileng holim'a mokotla o sirelelitsoeng.

Ho ka nka makhetlo a fetang a le mong ho fumana sampole ho lesea. Lesea le mafolofolo le ka tsamaisa mokotla, e le hore moroto o kene leletseng. Lekola lesea khafetsa ebe o chencha mokotla kamora hore moroto o bokelloe. Ntša moroto ka mokotleng o o kenya ka setshelong seo u se filoeng ke mofani oa hau.

Isa sampole ho laborateng kapa mofani oa thepa oa hau kapele kamoo ho ka khonehang kamora hore e phethoe.

Ha ho mehato e ikhethileng e hlokahalang bakeng sa tlhahlobo ena.

Teko e kenyelletsa feela ho ntša metsi ka mokhoa o tloaelehileng. Ha ho na bothata.

Hangata tlhahlobo ena e sebelisoa ho hlahloba boteng ba liprotheine tse itseng tse bitsoang monoclonal immunoglobulins. Liprotheine tsena li hokahane le myeloma le Waldenström macroglobulinemia. Teko e boetse e etsoa ka teko ea mali ho hlahloba monoglonal immunoglobulin serum.

Ho hloka li-immunoglobulin tse le 'ngoe morotong ke sephetho se tloaelehileng.

Boteng ba liprotheine tse monoclonal bo ka supa:

• Kankere e amang sesole sa 'mele, joalo ka myeloma kapa Waldenström macroglobulinemia
• Mefuta e meng ea mofetše

Immunofixation e ts'oana le moroto immunoelectrophoresis, empa e ka fana ka liphetho tse potlakileng haholoanyane.

McPherson RA, Riley RS, Massey HD. Tlhatlhobo ea laboratori ea ts'ebetso ea immunoglobulin le boits'ireletso ba boits'oaro. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. St Louis, MO: Elsevier; 2017: khaolo ea 46.

Treon SP, Castillo JJ, Hunter ZR, Merlini G. Waldenström macroglobulinemia / lymphoplasmacytic lymphoma. Ka: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Melao-motheo le Tloaelo ea Motheo. La 7th. Philadelphia, PA: Elsevier; 2018: khaolo ea 87.