Sesole sa mmele sa Antimitochondrial

Likokoana-hloko tsa Antimitochondrial (AMA) ke lintho (li-antibodies) tse thehang khahlanong le mitochondria. Mitochondria ke karolo ea bohlokoa ea lisele. Ke mohloli oa matla o kahare ho lisele. Tsena li thusa lisele ho sebetsa hantle.

Sengoliloeng sena se bua ka tlhahlobo ea mali e sebelisitsoeng ho lekanya palo ea AMA maling.

Ho hlokahala sampole ea mali. Hangata e nkoa mothapong. Tsamaiso e bitsoa venipuncture.

Mofani oa hao oa tlhokomelo ea bophelo a ka u joetsa hore u se ke ua ja kapa oa noa letho ho fihlela lihora tse 6 pele ho tlhahlobo (hangata bosiu bo le bong).

Ha nale e kentsoe ho hula mali, batho ba bang ba utloa bohloko bo itekanetseng. Ba bang ba ka ikutloa ba hlabehile kapa ba hlabeha feela. Kamora moo, ho kanna ha ba le ho tsitsipana.

U kanna oa hloka tlhahlobo ena haeba u na le matšoao a tšenyo ea sebete. Teko ena e sebelisoa khafetsa ho fumana biliary cholangitis ea mantlha, eo pele e neng e bitsoa primary biliary cirrhosis (PBC).

Teko e kanna ea sebelisoa ho tseba phapang lipakeng tsa lefu la ho thatafala ha sebete le mathata a sebete ka lebaka la lisosa tse ling tse kang ho koaloa, lefu la sebete la vaerase kapa lefu la ho thatafala ha joala.

Ka tloaelo, ha ho na lisireletsi tse teng.

Teko ena e bohlokoa bakeng sa ho fumana PBC. Hoo e ka bang batho bohle ba nang le boemo bona ba tla ba le tšoaetso. Ke ka seoelo motho ea se nang boemo a ka bang le litholoana tse ntle. Leha ho le joalo, batho ba bang ba nang le teko e nepahetseng bakeng sa AMA mme ha ho na letšoao le leng la lefu la sebete le ka tsoelang pele ho ea PBC ha nako e ntse e tsamaea.

Hangata, ho ka fumanoa liphetho tse sa tloaelehang tse bakoang ke mefuta e meng ea lefu la sebete le mafu a mang a 'mele.

Likotsi tsa ho huloa mali li nyane empa li ka kenyelletsa:

• Ho tsoa mali a mangata
• Ho akheha kapa ho ikutloa o le hlooho e boima
• Hematoma (mali a bokellanang ka tlasa letlalo)
• Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

• Teko ea mali

Li-Beuers U, Gershwin ME, Gish RG, le al. Nomenclature e fetolang PBC: Ho tloha ho 'cirrhosis' ho ea 'cholangitis'. Kliniki ea Hepatol Gastroenterol. 2015; 39 (5): e57-e59. PMID: 26433440 www.ncbi.nlm.nih.gov/pubmed/26433440.

CC ea Chernecky, Berger BJ. A. Ka: Chernecky CC, Berger BJ, bahlophisi. Liteko tsa Laboraro le Mekhoa ea Tlhatlhobo. La 6th. St Louis, MO: Elsevier Saunders; 2013: 84-180.

Eaton JE, Lindor KD. Cirrhosis ea mantlha ea biliary. Ka: Feldman M, Friedman LS, Brandt LJ, bahlophisi. Sleisenger le Fordtran's Mafu a ka Mpeng le a Sebete: Pathophysiology / Diagnosis / Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 91.

Kakar S. Primary biliary cholangitis. Ka: Saxena R, ed. E sebetsang ea Hepatic Pathology: Mokhoa oa ho Itlhahloba. Lekhetlo la bobeli. Philadelphia, PA: Elsevier; 2018: khaolo ea 26.

Zhang J, Zhang W, Leung PS, le al. Ts'ebetso e tsoelang pele ea lisele tsa B tse ikhethileng tsa autoantigen ho cirrhosis ea mantlha ea biliary. Hepatology. 2014; 60 (5): 1708-1716. PMID: 25043065 www.ncbi.nlm.nih.gov/pubmed/25043065.