Khaello ea khetho ea IgA

Ho haella ha IgA ke boloetse bo tloaelehileng haholo ba khaello ea 'mele. Batho ba nang le bothata bona ba na le protheine e maling e bitsoang immunoglobulin A.

Khaello ea IgA hangata e futsitsoe, ho bolelang hore e fetisoa ke malapa. Leha ho le joalo, ho boetse ho na le linyeoe tsa khaello ea IgA e bakoang ke lithethefatsi.

E kanna ea futsetsoa joalo ka tšobotsi e ikhethileng ea autosomal kapa autosomal. Hangata e fumanoa ho batho ba tsoang Europe. Ha e atisehe hakaalo ho batho ba merabe e meng.

Batho ba bangata ba nang le khaello ea IgA e khethiloeng ha ba na matšoao.

Haeba motho a e-na le matšoao, a ka kenyelletsa liketsahalo tsa khafetsa tsa:

• Bronchitis (tšoaetso ea sefofane)
• Letšollo le sa foleng
• Conjunctivitis (tšoaetso ea mahlo)
• Ho ruruha ha mpa, ho kenyelletsa le ulcerative colitis, lefu la Crohn le lefu le kang la sprue
• Tšoaetso ea molomo
• Otitis media (tšoaetso ea tsebe e bohareng)
• Pneumonia (tšoaetso ea matšoafo)
• Sinusitis (tšoaetso ea sinus)
• Tšoaetso ea letlalo
• Matšoao a kaholimo a phefumoloho

Matšoao a mang a kenyelletsa:

• Bronchiectasis (lefu leo ​​ho lona mekotla e menyenyane ea moea matšoafong e senyehang le ho holisoa)
• Pherekano ntle le lebaka le tsejoang

Ho kanna ha ba le nalane ea lelapa ea khaello ea IgA. Liteko tse ka etsoang li kenyelletsa:

• Litekanyo tsa sehlopha sa IgG
• Li-immunoglobulin tse ngata
• Serum immunoelectrophoresis

Ha ho kalafo e khethehileng e fumanehang. Batho ba bang butle-butle ba ba le maemo a tloaelehileng a IgA ntle le kalafo.

Kalafo e kenyelletsa ho nka mehato ea ho fokotsa palo le ho tiea ha tšoaetso. Hangata lithibela-mafu lia hlokahala ho phekola tšoaetso ea baktheria.

Li-immunoglobulin li fanoa ka methapo kapa ka ente ho matlafatsa sesole sa 'mele.

Kalafo ea mafu a ikemetseng e ipapisitse le bothata bo itseng.

Tlhokomeliso: Batho ba nang le khaello e felletseng ea IgA ba ka hlahisa lithibela-mafu tse khahlanong le IgA haeba ba fuoa lihlahisoa tsa mali le li-immunoglobulin. Sena se ka lebisa ho alejiki kapa ts'oaetsong ea anaphylactic. Leha ho le joalo, ba ka fuoa li-immunoglobulin tse felisitsoeng ke IgA ka polokeho.

Khaello ea khethollo ea IgA ha e kotsi ho feta mafu a mang a mangata a ho itšireletsa mafung.

Batho ba bang ba nang le khaello ea IgA ba tla fola ba le bang mme ba hlahise IgA ka bongata ho feta nako ea lilemo.

Mathata a ho itšireletsa mafung a kang ramatiki ea ramatiki, systemic lupus erythematosus le celiac sprue li ka hlaha.

Batho ba nang le khaello ea IgA ba ka hlahisa li-antibodies ho IgA. Ka lebaka leo, ba ka ba le tšusumetso e matla, e behang bophelo kotsing litšelong tsa mali le lihlahisoa tsa mali.

Haeba u na le khaello ea IgA, etsa bonnete ba hore u e tlalehela mofani oa tlhokomelo ea bophelo haeba immunoglobulin kapa litšelo tse ling tsa mali li hlahisoa e le kalafo ea boemo bofe kapa bofe.

Keletso ea lefutso e ka ba ea bohlokoa ho bao e tla ba batsoali ba nang le nalane ea lelapa ea khethollo ea IgA.

Khaello ea IgA; Ho itšireletsa maikutlong - khaello ea IgA; Ho itšireletsa mafung - khaello ea IgA; Hypogammaglobulinemia - Khaello ea IgA; Agammaglobulinemia - Khaello ea IgA

• Masole a mmele

Cunningham-Rundles C. Maloetse a mantlha a ho itšireletsa mafung. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 236.

Sullivan KE, Buckley RH. Liphoso tsa mantlha tsa tlhahiso ea antibody. Ka: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, bahlophisi. Buka ea Nelson ea Pediatrics. La 21 Ed. Philadelphia, PA: Elsevier; 2020: khaolo ea 150.