Liphoso tsa Congenital platelet function

Liphoso tsa congenital platelet function ke maemo a thibelang ho koala likarolo tsa mali, tse bitsoang li-platelet, hore li se ke tsa sebetsa kamoo li lokelang. Liplatelete li thusa lesela la mali. Congenital e bolela ho ba teng ho tloha tsoalong.

Liphoso tsa Congenital platelet function ke mathata a tsoang mali a bakang ts'ebetso ea "platelet" e fokotsehileng.

Boholo ba nako, batho ba nang le mathata ana ba na le nalane ea malapa ea lefu la ho tsoa mali, joalo ka:

• Lefu la Bernard-Soulier le hlaha ha liplatelete li haelloa ke ntho e khomarelang maboteng a methapo ea mali. Liplatelete hangata li kholo ebile li na le palo e fokotsehileng. Boloetse bona bo ka baka tšollo ea mali e matla.
• Glanzmann thrombasthenia ke boemo bo bakoang ke ho haella ha protheine e hlokahalang hore liplatelete li kopane. Liplatelete hangata li na le boholo le palo e tloaelehileng. Lefu lena le ka baka tšollo ea mali e matla.
• Platelet storage pool disorder (eo hape e bitsoang platelet secretion disorder) e etsahala ha lintho tse bitsoang li-granules ka hare ho liplatelete li sa bolokoe kapa li lokolloe hantle. Li-granules li thusa liplatelete hore li sebetse hantle. Boloetse bona bo baka ho longoa kapa ho tsoa mali habonolo.

Matšoao a ka kenyelletsa efe kapa efe ea tse latelang:

• Ho tsoa mali a mangata nakong ea kamora 'me ka mor'a ho buuoa
• Marenene a tsoang mali
• Ho loma habonolo
• Linako tse matla tsa ho ilela khoeli
• Ho tsoa mali
• Ho tsoa mali nako e telele ka likotsi tse nyane

Liteko tse latelang li ka sebelisoa ho fumana boemo bona:

• Palo e felletseng ea mali (CBC)
• Nako ea karoloana ea thromboplastin (PTT)
• Teko ea pokello ea Platelet
• Nako ea Prothrombin (PT)
• Tlhatlhobo ea mosebetsi oa Platelet
• Phallo ea cytometry

U kanna ua hloka liteko tse ling. Beng ka uena ba ka 'na ba hloka ho hlahlojoa.

Ha ho na kalafo e khethehileng bakeng sa mathata ana. Leha ho le joalo, mofani oa tlhokomelo ea bophelo ba hau o kanna a lekola boemo ba hau.

U kanna ua hloka:

• Ho qoba ho noa aspirin le lithethefatsi tse ling tsa anti-inflammatory (NSAIDs), tse kang ibuprofen le naproxen, hobane li ka mpefatsa matšoao a ho tsoa mali.
• Litšelo tsa Platelet, joalo ka nakong ea ts'ebetso ea opereishene kapa ea meno.

Ha ho na pheko bakeng sa mathata a amanang le ts'ebetso ea platelet. Boholo ba nako, kalafo e ka laola ho tsoa mali.

Mathata a ka kenyelletsa:

• Ho tsoa mali haholo
• Khaello ea khaello ea tšepe ho basali ba matsatsing

Bitsa mofani oa hau haeba:

• U tsoa mali kapa u tsoa likoto 'me ha u tsebe sesosa.
• Ho tsoa mali ha ho arabele mokhoeng o tloaelehileng oa taolo.

Teko ea mali e ka fumana lefutso le ikarabellang bakeng sa sekoli sa platelet. U kanna ua lakatsa ho batla tlhabollo ea lefutso haeba u na le nalane ea lelapa ka bothata bona mme u nahana ho ba le bana.

Bothata ba letamo la polokelo ea platelet; Thrombasthenia ea Glanzmann; Lefu la Bernard-Soulier; Liphoso tsa mosebetsi oa Platelet - congenital

• Ho thehoa ha mali
• Ho koala mali

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Holo ea JE. Hemostasis le coagulation ea mali. Ka: Holo ea JE, ed. Buka ea Guyton le Hall ea Physiology ea Bongaka. 13th ed. Philadelphia, PA: Elsevier; 2016: khaolo ea 37.

Mokha oa Nichols WL. Lefu la Von Willebrand le ho se tloaelehang ha hemorrhagic ha platelet le ts'ebetso ea methapo. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 173.