Mofuta o mong oa renal tubular acidosis

Distal renal tubular acidosis ke lefu le hlahang ha liphio li sa tlose li-acid maling ka mokhoa o nepahetseng. Ka lebaka leo, acid e ngata e sala maling (e bitsoang acidosis).

Ha 'mele o etsa mesebetsi ea ona e tloaelehileng, o hlahisa acid. Haeba asiti ena e sa tlosoe kapa e fokotsoa, ​​mali a fetoha asiti haholo. Sena se ka baka ho se leka-lekane ha elektrolyte maling. E ka baka mathata le ts'ebetso e tloaelehileng ea lisele tse ling.

Liphio li thusa ho laola boemo ba asiti ea ’mele ka ho tlosa asiti maling le ho a ntša ka har’a moroto.

Distal renal tubular acidosis (mofuta I RTA) e bakoa ke bofokoli ba methapo ea liphio bo bakang asiti ho aha maling.

Mofuta oa I RTA o bakoa ke maemo a fapaneng, ho kenyeletsoa:

• Amyloidosis, protheine e sa tloaelehang, e bitsoang amyloid, ka har'a lisele le litho
• Lefu la Fabry, sehahi se sa tloaelehang 'meleng oa mofuta o itseng oa mafura
• Boemo bo phahameng ba khalsiamo maling
• Boloetse ba lisele tsa boloetse, lisele tse khubelu tsa mali tse atisang ho bōptjoa joaloka disk li nka sekele kapa sebopeho sa seoli
• Sjögren syndrome, lefu le ikemetseng leo ho lona litšoelesa tse hlahisang meokho le mathe li senngoang
• Systemic lupus erythematosus, lefu le itšireletsang mafung ao ho 'ona sesole sa' mele se hlaselang lisele tse phetseng hantle ka phoso
• Lefu la Wilson, lefu le futsitsoeng leo ho lona ho nang le koporo e ngata haholo liseleng tsa 'mele
• Tšebeliso ea meriana e meng, e kang amphotericin B, lithium le analgesics

Matšoao a distal renal tubular acidosis a kenyelletsa tse latelang:

• Ho ferekana kapa ho fokotsa ho falimeha
• Mokhathala
• Khōlo e senyehileng ho bana
• Ho phefumoloha ho eketsehileng
• Majoe a liphio
• Nephrocalcinosis (calcium e ngata haholo e bolokiloeng liphio)
• Osteomalacia (ho nolofatsa masapo)
• Bofokoli ba mesifa

Matšoao a mang a kenyeletsa:

• Bohloko ba masapo
• Ho fokotsa tlhahiso ea moroto
• Ho eketseha ha lebelo la pelo kapa ho otla ha pelo ka tsela e sa tloaelehang
• Maqhubu a mesifa
• Bohloko bo ka morao, lehlakore, kapa mpa
• Bothata ba masapo

Mofani oa tlhokomelo ea bophelo o tla etsa tlhahlobo ea 'mele mme a botse ka matšoao a hau.

Liteko tse ka laeloang li kenyelletsa:

• Khase ea mali ea mali
• Khemistri ea mali
• Moroto pH
• Teko ea mojaro oa acid
• Teko ea infusion ea Bicarbonate
• Ho hlahloba urinal

Li-calcium tse bolokiloeng liphio le majoe a liphio li ka bonoa ho:

• Li-X-ray
• Ultrasound
• CT scan

Morero ke ho khutlisa boemo bo tloaelehileng ba acid le botsitso ba electrolyte 'meleng. Sena se tla thusa ho lokisa mathata a masapo le ho fokotsa calcium buildup liphio (nephrocalcinosis) le majoe a liphio.

Lebaka le ka sehloohong la distal renal tubular acidosis le lokela ho lokisoa haeba le ka tsejoa.

Meriana e ka laeloang e kenyelletsa potasiamo citrate, sodium bicarbonate, le thiazide diuretics. Tsena ke meriana ea alkaline e thusang ho lokisa boemo ba asiti ea 'mele. Bicarbonate ea sodium e ka lokisa tahlehelo ea potasiamo le khalsiamo.

Boloetse bona bo tlameha ho phekoloa ho fokotsa litlamorao le mathata a teng, a ka bang teng ka ho sa feleng kapa a behang bophelo kotsing. Maemong a mangata a ba betere ka kalafo.

Bitsa mofani oa hau haeba u na le matšoao a distal renal tubular acidosis.

Fumana thuso ea bongaka hang-hang haeba u ba le matšoao a tšohanyetso a kang:

• Ho fokotseha ha tsebo
• Ho oa
• Ho theoha ho matla ha temoso kapa boits'oaro

Ha ho na thibelo ea lefu lena.

Renal tubular acidosis - distal; Renal tubular acidosis mofuta oa I; Tlanya I RTA; RTA - distal; RTA ea khale

• Anatomy ea liphio
• Liphio - phallo ea mali le moroto

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Dixon BP. Renal tubular acidosis. Ka: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Buka ea Nelson ea Pediatrics. La 21 Ed. Philadelphia, PA: Elsevier; 2020: khaolo ea 547.

Seifter JL. Mathata a acid-base. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 110.