Kalafo bakeng sa Pherekano ea Eosinophilic
Litaba
- Inhaled le molomo corticosteroids
- Liphetoho tsa Leukotriene
- Likokoana-hloko
- Pholoso inhalers
- Li-anticholinergics
- Tsela
Asosma asthma ke karoloana ea asma eo hangata e hlahang hamorao bophelong. Karolelano ea lilemo tsa ho qala li pakeng tsa lilemo tse 35 le 50. E ka ba teng ho batho ba e-s'o fumanoe hore ba na le asthma.
Mofuta ona oa asma e bakoa ke tšubuhlellano ea lisele tsa mali tsa eosinophil. Le ha sesosa se sa tsejoeng se sa tsejoe, li-eosinophil li ka kenya letsoho ho ruruheng ha moea le pherekano e bonoang mefuteng ea setso ea asthma.
Asma eosinophilic e ka baka matšoao a matla ho feta mefuta e bonolo ea asma. U kanna oa ba le likhahla khafetsa. Khetho ea kalafo e ts'oana le asma e matla, empa mekhoa ea hau ea kalafo hangata e matla haholo.
Bua le ngaka ea hau ka likhetho tse latelang tse sebelisitsoeng ho phekola mofuta ona oa asthma.
Inhaled le molomo corticosteroids
Inhaled corticosteroids hangata ke mohala oa pele oa kalafo bakeng sa mefuta e phehellang ea, ho kenyelletsa le eosinophilic, asthma. Ba sebetsa ka ho fokotsa ho ruruha ha moea o kenang moeeng, ho o nolofalletsang ho hema habonolo.
U kanna ua hloka mefuta e meng ea li-corticosteroids bakeng sa asthma ea molomo ka molomo haeba matšoao a hau a le matla le ho feta.
Leha ho le joalo, li-steroids tsa molomo li beha kotsi ea litla-morao tsa nako e telele, ho kenyelletsa:
- lefu la ho fokola ha masapo
- boima ba 'mele
- lefu la tsoekere
Liphetoho tsa Leukotriene
Hangata meriana ena ea molomo e fuoa batho ba nang le asthma le allergies. Li sebetsa ka ho fokotsa leukotrienes 'meleng, tse tlatsetsang ho ruruheng.
Ngaka ea hau e ka u fa e 'ngoe ea tse latelang:
- sodium ea montelukast (Singulair)
- zafirlukast (E nepahetse)
- zileuton (Zyflo)
Likokoana-hloko
Biologics ke mofuta o hlahang oa kalafo e matla ea asma. Meriana ena e fanoa ka ente, hangata ke ngaka ea hau. Ba fokotsa ho ruruha ka ho lebisa limolek'hule tse ruruhang, lisele le lisireletsi.
Ka lebaka lena, biologics e nkuoa e fana ka kalafo e "ikhethileng" ho feta meriana e meng ea asthma.
U kanna ua ba moemeli oa biologics haeba u ntse u tsoelapele ho ba le li-flare-up khafetsa leha u noa meriana ea molaoli oa hau ebile u qoba lintho tse ka u bakang.
Biologics e ka boela ea fokotsa asma ea bosiu, hape ea fokotsa palo ea maeto a sepetlele a tsoang ho litlhaselo tsa asthma.
Hona joale ho na le mefuta e mehlano ea biologics e fumanehang bakeng sa kalafo e matla ea asthma:
- benralizumab (Fasenra)
- dupilumab (Dupixent)
- mepolizumab (Nucala)
- omalizumab (Xolair)
- reslizumab (Cinqair)
Ho tsena tsa biologics, Fasenra, Nucala le Cinqair kaofela li shebile li-eosinophil ka ho khetheha. Li-biologics tse ngata li nts'etsopele bakeng sa kalafo e shebiloeng haholoanyane.
Haeba ngaka ea hau e khothaletsa biologics bakeng sa asthma ea hau eosinophilic, o ka lebella ho fumana liente tsena libeke tse 2 ho isa ho tse 8 nakong ea bonyane likhoeli tse 4.
Pholoso inhalers
Le ha e se mofuta oa kalafo oa nako e telele, e ntse e le mohopolo o motle ho ba le pholoso ea letsoho ha o na le asthma eosinophilic.
E boetse e bitsoa inhaler ea liphallelo e potlakileng, meriana ena e sebetsa ka ho fokotsa matšoao a ho phatloha le ho bula lifofane tsa hau ho thusa ho thibela tlhaselo ea asthma.
Bothata ba li-inhalers tsa pholoso ke hore li ke ke tsa thibela matšoao a asthma joalo ka ha balaoli ba nako e telele ba etsa. Ho itšetleha ka mefuta ena ea li-inhalers khafetsa le hona ho ka etsa hore e se sebetse hantle hobane matšoafo a hau a tla a tloaela.
Bitsa ngaka ea hau haeba u sebelisa pholoso ea hau ho feta makhetlo a 'maloa ka beke.
Li-anticholinergics
Anticholinergics ke meriana e thibelang neurotransmitter e bitsoang acetylcholine. Lithethefatsi tsena ka tloaelo li phekola ho hloka botsitso le senya se fetang tekano, hammoho le lefu le sa foleng la pulmonary pulmonary (COPD).
Mefuta ena ea meriana e ka thusa ho phekola asma e matla. Li-anticholinergics li khatholla mesifa ea moea le ho o thusa ho hema habonolo.
Ho noa meriana ena ho ka etsa hore ho se be bonolo hore o tla hloka li-steroid tsa molomo nakong e telele.
Tsela
Asma ea asosophophic ke e 'ngoe ea li-subtypes tse thata ka ho fetisisa tsa asthma ho li phekola. Mohlomong u tla hloka ho leka likhetho tse fapaneng ho bona hore na ke eng e sebetsang hantle.
Asthma ea hau e nkoa e "laoloa hantle" haeba u na le matšoao a matsatsi a 2 ka beke kapa ka tlase.
Bua le ngaka ea hau haeba u e-na le matšoao a asthma khafetsa mme haeba boemo ba hau bo sitisa mesebetsi ea letsatsi le letsatsi. Ba kanna ba fana ka meriana e matla ea nako e telele kapa biologics ho thusa ho ntlafatsa matšoao a hau le boleng ba bophelo.
Ho laola matšoao a asthma asthma ho ka thusa ho fokotsa menyetla ea ho hlaseloa ke matšoafo le mathata a mang a nako e telele.
U ka ntlafatsa litlamorao tsa kalafo ka ho hlokomela bophelo ba hau ka kakaretso kamoo ho ka khonehang, ho kenyelletsa:
- ho ja hantle
- ho robala ka ho lekaneng
- ho laola khatello ea maikutlo
Ho qoba lintho tse ka u bakang, tse kang khatello ea maikutlo, ho kula, le lintho tse halefisang lik'hemik'hale, le hona ho ka fokotsa menyetla ea ho hlaseloa.