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Letsatsi La Creation: 1 Phupu 2021
Ntlafatsa Letsatsi: 15 December 2024
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Teko ea cortisol ke eng?

Cortisol ke hormone e amang hoo e batlang e le setho se seng le se seng sa mmele oa hau. E bapala karolo ea bohlokoa ho u thusa ho:

  • Arabela khatello ea maikutlo
  • Loantša tšoaetso
  • Laola tsoekere maling
  • Boloka khatello ea mali
  • Laola metabolism, ts'ebetso ea hore na 'mele oa hau o sebelisa lijo le matla joang

Cortisol e entsoe ke litšoelesa tsa hau tsa adrenal, litšoelesa tse peli tse nyane tse kaholimo ho liphio. Teko ea cortisol e lekanya boemo ba cortisol maling a hao, morong kapa mathe. Liteko tsa mali ke eona mokhoa o tloaelehileng haholo oa ho metha cortisol. Haeba maemo a hau a cortisol a phahame haholo kapa a le tlase haholo, ho ka bolela hore o na le bothata ba litšoelesa tsa hau tsa adrenal. Mathata ana a ka ba matla haeba a sa phekoloe.

Mabitso a mang: cortisol ea ho ntša metsi, cortisol ea salivary, cortisol ea mahala, teko ea khatello ea dexamethasone, DST, teko ea ho hlasimolla ea ACTH, cortisol ea mali, plasma cortisol, plasma

E sebelisetsoa eng?

Ho sebelisoa teko ea cortisol ho thusa ho fumana mafu a adrenal gland. Tsena li kenyelletsa Cushing's syndrome, boemo bo etsang hore 'mele oa hau o etse cortisol e ngata haholo, le lefu la Addison, boemo boo' mele oa hau o sa etsang cortisol e lekaneng.


Hobaneng ha ke hloka tlhahlobo ea cortisol?

U kanna oa hloka tlhahlobo ea cortisol haeba u na le matšoao a Cushing's syndrome kapa lefu la Addison.

Matšoao a Cushing's syndrome a kenyelletsa:

  • Botenya, haholo-holo torso
  • Khatello ea mali e phahameng
  • Tsoekere e phahameng maling
  • Mebala e pherese ka mpeng
  • Letlalo le tlabolang habonolo
  • Bofokoli ba mesifa
  • Basali ba ka ba le linako tse sa tloaelehang tsa ho ilela khoeli le moriri o mongata sefahlehong

Matšoao a lefu la Addison a kenyelletsa:

  • Ho fokotsa boima ba 'mele
  • Mokhathala
  • Bofokoli ba mesifa
  • Bohloko ba mpeng
  • Matlalo a lefifi a letlalo
  • Khatello ea mali e tlase
  • Ho nyekeloa le ho hlatsa
  • Letšollo
  • Ho fokotsa moriri oa 'mele

U kanna ua hloka tlhahlobo ea cortisol haeba u na le matšoao a bothata ba adrenal, boemo bo sokelang bophelo bo ka etsahalang ha maemo a hau a cortisol a le tlase haholo. Matšoao a koluoa ​​ea adrenal a kenyelletsa:

  • Khatello ea mali e tlase haholo
  • Ho hlatsa haholo
  • Letšollo le matla
  • Ho felloa ke metsi 'meleng
  • Mahlaba a tšohanyetso le a bohloko ka mpeng, mokokotlong le maotong
  • Pherekano
  • Ho lahleheloa ke kelello

Ho etsahalang nakong ea teko ea cortisol?

Teko ea cortisol hangata e etsoa ka tlhahlobo ea mali. Nakong ea tlhahlobo ea mali, setsebi sa tlhokomelo ea bophelo se tla nka sampole ea mali mothapong o letsohong la hao, a sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.


Hobane maemo a cortisol a fetoha ho pholletsa le letsatsi, nako ea teko ea cortisol e bohlokoa. Teko ea mali ea cortisol hangata e etsoa habeli ka letsatsi – hanngoe hoseng ha maemo a cortisol a le holimo ka ho fetesisa, hape hape ka hora ea bone thapama, ha maemo a le tlase haholo.

Cortisol le eona e ka lekanyetsoa tekong ea moroto kapa mathe. Bakeng sa tlhahlobo ea moroto oa cortisol, mofani oa tlhokomelo ea bophelo a ka u kopa hore u bokelle moroto ohle nakong ea lihora tse 24. Sena se bitsoa "tlhahlobo ea sampole ea lihora tse 24". E sebelisoa hobane maemo a cortisol a fapana ho pholletsa le letsatsi. Bakeng sa tlhahlobo ena, mofani oa tlhokomelo ea bophelo bo botle kapa setsebi sa laboratori o tla u fa setshelo ho bokella moroto oa hau le litaelo tsa hore na u ka bokella le ho boloka mehlala ea hau joang. Teko ea sampole ea lihora tse 24 ea moroto hangata e kenyelletsa mehato e latelang:

  • Hlakola senya ea hao hoseng 'me u ntše metsi ao. Ngola nako.
  • Bakeng sa lihora tse 24 tse latelang, boloka moroto oa hau o felletse ka setshelong se fanoeng.
  • Boloka setshelo sa hau sa moroto ka sehatsetsing kapa se pholileng se nang le leqhoa.
  • Khutlisetsa setshelo sa sampole ofising ea mofani oa bophelo bo botle kapa laboratoring joalokaha ho laetsoe.

Teko ea mathe ea cortisol hangata e etsoa hae, bosiu haholo, ha maemo a cortisol a le tlase. Mofani oa hao oa tlhokomelo ea bophelo o tla u khothaletsa kapa au fe lisebelisoa tsa tlhahlobo ena. The kit e kanna ea kenyelletsa swab ho lata sampole ea hau le setshelo ho e boloka. Mehato hangata e kenyelletsa tse latelang:


  • Se ke oa ja, oa noa kapa oa hlatsoa meno metsotso e 15-30 pele ho tlhahlobo.
  • Bokella sampole pakeng tsa 11 bosiu. le hara mp'a bosiu, kapa joalo ka ha ho laetsoe ke mofani oa hau.
  • Kenya swab ka hanong la hao.
  • Rolela swab molomong oa hau nako e ka etsang metsotso e 2 hore e koaheloe ke mathe.
  • Se ke oa ama ntlha ea swab ka menoana ea hau.
  • Kenya swab ka har'a setshelo ebe u e khutlisetsa ho mofani oa hau joalo ka ha u laetsoe.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ho imeloa kelellong ho ka nyolla maemo a cortisol ea hau, ka hona o ka hloka ho phomola pele ho tlhahlobo ea hau. Teko ea mali e tla hloka hore u hlophise likopano tse peli ka linako tse fapaneng tsa letsatsi. Liteko tsa moroto le mathe lihoreng tse mashome a mabeli a metso e mene li etsoa hae. Etsa bonnete ba hore u latela litaelo tsohle tse fanoang ke mofani oa hau.

Na ho na le likotsi tsa tlhahlobo?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele. Ha ho na likotsi tse tsebahalang tlhahlobisong ea moroto kapa mathe.

Liphetho li bolelang?

Maemo a phahameng a cortisol a ka bolela hore o na le Cushing's syndrome, ha maemo a tlase a ka bolela hore o na le lefu la Addison kapa mofuta o mong oa lefu la adrenal. Haeba liphetho tsa hau tsa cortisol li sa tloaeleha, ha ho bolele hore o na le boemo ba bongaka bo hlokang kalafo. Lintlha tse ling, ho kenyelletsa ts'oaetso, khatello ea maikutlo le bokhachane li ka ama sephetho sa hau. Lipilisi tsa thibelo ea bokhachane le meriana e meng le tsona li ka ama maemo a hau a cortisol. Ho ithuta hore na liphetho tsa hau li bolelang, bua le mofani oa tlhokomelo ea bophelo.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea cortisol?

Haeba maemo a hau a cortisol a sa tloaeleha, mofani oa hao oa tlhokomelo ea bophelo o tla odara liteko tse ngata pele a ka fumanoa. Liteko tsena li ka kenyelletsa liteko tse ling tsa mali le moroto le liteko tsa ho nka litšoantšo, joalo ka litlhahlobo tsa CT (computerised tomography) le MRI (magnetic resonance imaging), tse lumellang mofani oa hau ho sheba litšoelesa tsa hau tsa adrenal le pituitary.

Litšupiso

  1. Allina Health [Inthanete]. Allina Bophelo; c2017. Mokhoa oa ho bokella sampole ea mathe bakeng sa teko ea Cortisol [e qotsitsoeng ka 2017 Phupu 10]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.allinahealth.org/Medical-Services/SalivaryCortisol15014
  2. Hinkle J, Cheever K. Brunner & Suddarth's Handbook ea Liteko tsa Laboraro le Tlhatlhobo. 2ke Monghali, Kindle.Philadelphia: Wolters Kluwer Bophelo, Lippincott Williams & Wilkins; c2014. Cortisol, Lero la mali le Urine; 189-90 leq.
  3. Johns Hopkins Medicine [Inthanete]. Bongaka ba Johns Hopkins; Laeborari ea Bophelo: Litšoelesa tsa Adrenal [e boletsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: http://www.hopkinsmedicine.org/healthlibrary/conditions/adult/endocrinology/adrenal_glands_85,p00399
  4. Liteko tsa Lab Marang-rang [Inthaneteng]. Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2017. Cortisol: Lipotso tse Tloaelehileng [e ntlafalitsoeng ka 2015 Oct 30; e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 5]. E fumaneha ho tsoa ho: https://labtestsonline.org/understanding/analytes/cortisol/tab/faq
  5. Liteko tsa Lab Marang-rang [Inthaneteng]. Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2017. Cortisol: Teko [e ntlafalitsoeng ka 2015 Oct 30; e qotsitsoeng ka 2017 Phupu 10]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://labtestsonline.org/understanding/analytes/cortisol/tab/test
  6. Liteko tsa Lab Marang-rang [Inthaneteng]. Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2017. Cortisol: Sample Sample [e ntlafalitsoeng ka 2015 Oct 30; e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://labtestsonline.org/understanding/analytes/cortisol/tab/test
  7. Liteko tsa Lab Marang-rang [Inthaneteng]. Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2017. Lenane la mantsoe: Mohlala oa Urine ea Lihora tse 24 [e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://labtestsonline.org/glossary/urine-24
  8. Phetolelo ea Merck Manual Consumer [Inthanete]. Kenilworth (NJ): Merck & Co Inc .; c2017. Cushing Syndrome [e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: http://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/adrenal-gland-disorders/cushing-syndrome#v772569
  9. Phetolelo ea Merck Manual Consumer [Inthanete]. Kenilworth (NJ): Merck & Co Inc .; c2017. Kakaretso ea litšoelesa tsa Adrenal [e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: http://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/adrenal-gland-disorders/overview-of-the-adrenal-glands
  10. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Likotsi Tsa Liteko Tsa Mali ke Life? [e ntlafalitsoeng 2012 Jan 6; e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 6]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
  11. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Seo U ka se Lebellang ka Liteko tsa Mali [e ntlafalitsoeng ka 2012 Pherekhong 6; e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 5]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
  12. Setsi sa Naha sa Lefu la Ts'oaetso le Mafu a Ts'oaetso le Liphio [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Adrenal Insufficiency & Lefu la Addison; 2014 Mots'eanong [e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.niddk.nih.gov/health-information/endocrine-diseases/adrenal-insufficiency-addisons-disease
  13. Setsi sa Naha sa Lefu la Ts'oaetso le Mafu a Ts'oaetso le Liphio [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Cushing’s Syndrome; 2012 Apr [e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.niddk.nih.gov/health-information/endocrine-diseases/cushings-syndrome
  14. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2017. Health Encyclopedia: Cortisol (Mali) [e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=cortisol_serum
  15. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2017. Health Encyclopedia: Cortisol (Urine) [e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=cortisol_urine
  16. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2017. Tlhahisoleseling ea Bophelo: Metabolism [e ntlafalitsoeng 2016 Oct 13; e qotsitsoeng ka 2017 Phupu 10]; [li-skrini tse ka bang 5]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/definition/metabolism/stm159337.html#stm159337-sec

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.

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