Oli ea Litlhapi vs. Litempe: Ke Eng se Bolokang Cholesterol E Teng Tlase?

Litaba

• Metheo ea oli ea litlhapi
• Li-statin li sebetsa joang
• Seo lipatlisiso li se bolelang ka oli ea tlhapi
• Seo lipatlisiso li se bolelang ka li-statins
• Kahlolo
• Q&A: Lithethefatsi tse ling tsa k'holeseterole
• P:
• K:

Kakaretso

Cholesterol e phahameng e kanna ea se bake matšoao kamehla, empa e hloka kalafo ka ho tšoana. Ha ho tluoa ho laoleng k'holeseterole ea hau, li-statin ke morena.

Na oli ea tlhapi e ka sebetsa hantle joalo ho fokotsa k'holeseterole ea hau? Bala ho ea pele ho ithuta hore na e ipakela joang.

Metheo ea oli ea litlhapi

Oli ea tlhapi e na le omega-3 fatty acids, e tsejoang ka melemo e mengata ea bophelo bo botle. Har'a tse ling, omega-3 fatty acids ho boletsoe ho:

• loantša ho ruruha
• fokotsa khatello ea mali
• ntlafatsa bophelo bo botle ba masapo
• khothaletsa letlalo le phetseng hantle

Le ha e fumaneha ka tlhaho ho litlhapi, oli ea tlhapi hangata e nkuoa ka mokhoa oa tlatsetso.

Ka 2012, lihlahisoa tse sebelisitsoeng tse nang le oli ea tlhapi kapa omega-3 fatty acids.

Li-statin li sebetsa joang

Lipolelo li emisa 'mele ho etsa cholesterol. Ba boetse ba e thusa ho khutlisa lejoe le hahiloeng marakong a mothapo.

Phuputso e 'ngoe ea bolelele ba nako e fumane hore liperesente tsa 27.8 tsa MaAmerika ho feta lilemo tse 40 ba ne ba sebelisa li-statin ho tloha ka 2013.

Seo lipatlisiso li se bolelang ka oli ea tlhapi

Boithuto ka oli ea tlhapi bo kopantsoe. Lisebelisoa tsa oli ea tlhapi li tlamiloe lenaneng le lelelele la melemo, ho kenyeletsoa:

• fokotsa kotsi ea lefu la pelo le stroke
• maemo a tlase a triglycerides, kapa mafura maling
• bophelo bo eketsehileng ba boko
• taolo e ntle ea lefu la tsoekere

Liphuputso tse ling, joalo ka tse boletsoeng ho, li fumane kotsi e fokotsehileng ea lefu la pelo ho batho ba noang li-supplement tsa oli ea tlhapi. Boithuto bo bong, joalo ka teko e le 'ngoe ea kliniki ea 2013 ea batho ba 12,000 ba nang le mabaka a kotsi a pelo, ha ba fumane bopaki bo joalo.

Ho feta moo, leha oli ea tlhapi e fokotsa triglycerides, ha ho na bopaki bo lekaneng ba hore e theola kotsi ea lefu la pelo.

Ha ho tluoa ho theoleng lipoprotein (LDL) tse fokolang haholo, bopaki bo teng feela ha bo eo. Ebile, oli ea tlhapi e ka eketsa maemo a LDL ho batho ba bang ho latela tlhahlobo ea lingoliloeng ea 2013.

Seo lipatlisiso li se bolelang ka li-statins

Ho ea ka li-statin li bonts'a bokhoni bo ke keng ba hanyetsoa ba ho thibela lefu la pelo empa li lokela ho nkuoa ka hloko.

Lipolelo li na le melemo ntle le ho fokotsa k'holeseterole ea hau. Mohlala, li na le thepa e khahlanong le ho ruruha e ka sebetsang ho tsitsisa methapo ea mali, hape e ka thusa ho thibela litlhaselo tsa pelo, ho latela Mayo Clinic.

Ke ka lebaka la litla-morao tsa bona tse ka bang teng, joalo ka bohloko ba mesifa, hore ka kakaretso li fuoa feela batho ba nang le k'holeseterole e phahameng le kotsi ea lefu la pelo. Ha li nkuoe e le moriana o thibelang mafu.

Kahlolo

Haeba u na le k'holeseterole e phahameng, ho nka li-statin ke tsela e atlehang ea ho sebetsana le kotsi. Ho nka oli ea tlhapi ho ka ba le melemo ea eona, empa ho theola k'holeseterole ea hau ea LDL ha se e 'ngoe ea tsona.

Bua le ngaka ea hau ka likhetho tsa hau le melemo le likotsi tsa kalafo ea statin.

Batho ba bangata ba nka li-supplements e le mokhoa oa thibelo. Leha ho le joalo, tsela e molemohali ea ho thusa ho thibela k'holeseterole e phahameng ke ka ho etsa khetho e nepahetseng ea bophelo, ho kenyelletsa:

• ho tlohela ho tsuba
• ho ja lijo tse phetseng hantle tse nang le mafura a mangata
• ho laola boima ba 'mele oa hau

Q&A: Lithethefatsi tse ling tsa k'holeseterole

P:

Ke lithethefatsi life tse ling tse ka thusang ho theola k'holeseterole ea ka?

Mokuli ea sa tsejoeng

K:

Ntle le li-statin, lithethefatsi tse ling tse sebelisetsoang ho theola k'holeseterole li kenyelletsa:

• niacin
• lithethefatsi tse sebetsang ka maleng a hao
• likhoele
• PCSK9 inhibitors

Niacin ke vithamine ea B e fumanoang lijong 'me e fumaneha ka foromo ea ngaka ka litekanyetso tse phahameng. Niacin e theola kholeseterole ea LDL (e mpe) mme e phahamisa cholesterol ea HDL (e ntle). Lithethefatsi tse sebetsang ka maleng a hau li boetse li sebelisetsoa ho phekola k'holeseterole e phahameng ka ho thibela ho monya ha k'holeseterole mala a hao a manyane. Li kenyelletsa cholestyramine, colesevelam, colestipol le ezetimibe. Li-fibrate li thibela 'mele oa hau ho etsa triglycerides, kapa mafura, mme o phahamisa cholesterol ea hau ea HDL. Li-fibrate li kenyelletsa fenofibrate le gemfibrozil.

Meriana ea cholesterol e ncha ka ho fetisisa e amoheloang ke FDA ke PCSK9 inhibitors, e kenyeletsang alirocumab le evolocumab. Ba alafa haholo-holo bakuli ba nang le liphatsa tsa lefutso tse bakang hypercholesterolemia.

Bempedoic acid ke sehlopha se secha sa meriana se ntseng se etsoa hona joale. Liphuputso tsa pele li bontša tšepiso ho bokhoni ba eona ba ho phekola k'holeseterole e phahameng.

Dena Westphalen, PharmDAnswers e emela maikutlo a litsebi tsa rona tsa bongaka. Likahare tsohle li na le tlhaiso-leseling ka botlalo 'me ha lia lokela ho nkuoa joalo ka likeletso tsa bongaka.