5-HIAA tlhahlobo ea moroto

5-HIAA ke teko ea moroto e lekanyang boholo ba 5-hydroxyindoleacetic acid (5-HIAA). 5-HIAA ke sehlahisoa se senyehang sa hormone e bitsoang serotonin.

Teko ena e bolela hore na 'mele oa 5-HIAA o hlahisa bokae. Hape ke mokhoa oa ho lekanya hore na serotonin e kae 'meleng.

Ho hlokahala sampole ea lihora tse 24. U tla hloka ho bokella moroto oa hau ho feta lihora tse 24 ka setshelong se fanoeng ke laboratori. Mofani oa hao oa tlhokomelo ea bophelo o tla u joetsa hore na u ka etsa sena joang. Latela litaelo hantle.

Mofani oa hau o tla u laela, ha ho hlokahala, hore u khaotse ho noa meriana e ka sitisang tlhahlobo.

Meriana e ka eketsang litekanyo tsa 5-HIAA e kenyelletsa acetaminophen (Tylenol), acetanilide, phenacetin, glyceryl guaiacolate (e fumanoang lihlareng tse ngata tsa khohlela), methocarbamol le reserpine.

Meriana e ka fokotsang litekanyo tsa 5-HIAA e kenyelletsa heparin, isoniazid, levodopa, monoamine oxidase inhibitors, methenamine, methyldopa, phenothiazines le tricyclic antidepressants.

U tla bolelloa hore u se ke ua ja lijo tse itseng matsatsi a 3 pele ho tlhahlobo. Lijo tse ka sitisang litekanyo tsa 5-HIAA li kenyelletsa li-plums, liphaenapole, libanana, eggplant, tamati, avocado le walnuts.

Teko e kenyelletsa feela ho rota ho tloaelehileng, 'me ha ho na bothata.

Teko ena e lekanya boemo ba 5-HIAA ka morong. Hangata ho etsoa ho fumana lihlahala tse itseng tšilong ea lijo (carcinoid tumor) le ho lekola boemo ba motho.

Teko ea moroto e kanna ea sebelisoa ho fumana bothata bo bitsoang systemic mastocytosis le lihlahala tse ling tsa hormone.

Mefuta e tloaelehileng ke 2 ho 9 mg / 24h (10.4 ho 46.8 µmol / 24h).

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Li-lab tse ling li sebelisa litekanyo tse fapaneng kapa li leka liteko tse fapaneng. Bua le mofani oa hau ka moelelo oa sephetho sa hau sa liteko.

Liphetho tse sa tloaelehang li ka bakoa ke:

• Lihlahala tsa sistimi ea endocrine kapa lihlahala tsa carcinoid
• Ho eketsa lisele tsa 'mele tsa ho itšireletsa mafung tse bitsoang li-mast liseleng tse' maloa (systemic mastocytosis)

Ha ho na likotsi ka tlhahlobo ena.

HIAA; 5-hydroxyindole acetic acid; Metabolite ea Serotonin

CC ea Chernecky, Berger BJ. H. Ho: Chernecky CC, Berger BJ, bahlophisi. Liteko tsa Laboraro le Mekhoa ea Tlhatlhobo. La 6th. Philadelphia, PA: Elsevier Saunders; 2013: 660-661.

Wolin EM, Jensen RT. Lihlahala tsa Neuroendocrine. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 219.