CSF coccidioides e tlatselletsa teko ea ho lokisa
CSF coccidioides complement fixation ke teko e lekolang tšoaetso ka lebaka la fungus coccidioides mokelikeli oa cerebrospinal (CSF). Ena ke mokelikeli o pota-potileng boko le mokokotlo. Lebitso la tšoaetso ena ke coccidioidomycosis, kapa fever fever. Ha tšoaetso e kenyelletsa ho koahela boko le mokokotlo oa mokokotlo (meninges), e bitsoa coccidioidal meningitis.
Mohlala oa mokelikeli oa mokokotlo oa hlokahala bakeng sa tlhahlobo ena. Sampole hangata e fumanoa ka ho phunya lumbar (pompong ea mokokotlo).
Sampole e romelloa laboratoring. Ha e le moo, e hlahlojoa bakeng sa lithibela-mafu tsa coccidioides ho sebelisoa mokhoa oa laboratori o bitsoang complement fixation. Mokhoa ona o hlahloba hore na 'mele oa hau o hlahisitse lintho tse bitsoang li-antibodies nthong e itseng ea kantle ho naha (antigen), ntlheng ena coccidioides.
Masole a mmele ke diprotheine tse ikgethang tse sirelletsang mmele wa hao kgahlano le dibaktheria, divaerase le fungi. Ha masole a mmele a le teng, a itshwarella kapa a "itokisa" ho antigen. Ke kahoo teko e bitsoang "fixation."
Latela litaelo tsa mofani oa tlhokomelo ea bophelo mabapi le hore na u ka itokisetsa tlhahlobo joang. Lebella ho ba sepetlele ka lihora tse 'maloa ka mor'a moo.
Nakong ea tlhahlobo:
- U robala ka lehlakore u khumame ka mangole ho ea sefubeng ebe sefahleho se thellelletse tlase. Kapa, u lula fatše, empa u ikemiselitse pele.
- Kamora hore o hlwekise mokokotlo wa hao, ngaka e kenya moriana o thethefatsang wa selehae mokokotlong wa hao o ka tlase.
- Ho kenngoa nale ea mokokotlo, hangata sebakeng se ka tlase mokokotlong.
- Hang ha nale e lutse hantle, khatello ea CSF e ea lekanngoa ebe sampole ea bokelloa.
- Nale e tlosoa, sebaka se hloekisoa, 'me ho behoa bandage holim'a sebaka sa nale.
- U isoa sebakeng sa ho hlaphoheloa moo u phomolang lihora tse 'maloa ho thibela ho tsoa hoa CSF.
Teko ena e hlahloba hore na methapo ea hau ea methapo e na le ts'oaetso e sebetsang e tsoang coccidioides.
Ho ba sieo ha fungus (tlhahlobo e mpe) ho tloaelehile.
Haeba tlhahlobo e le ntle bakeng sa fungus, ho kanna ha ba le ts'oaetso e mafolofolo tsamaisong ea methapo e bohareng.
Teko e sa tloaelehang ea mokelikeli oa mokokotlo e bolela hore tsamaiso ea methapo e bohareng e tšoaelitsoe. Nakong ea bokuli, ho ka fumanoa li-antibodies tse fokolang. Tlhahiso ea lithibela-mafu e eketseha nakong ea ts'oaetso. Ka lebaka lena, tlhahlobo ena e ka phetoa libeke tse 'maloa kamora teko ea pele.
Likotsi tsa ho koaloa lumbar li kenyelletsa:
- Ho tsoa mali ka har'a kanale ea mokokotlo
- Ho se utloise bohloko nakong ea tlhahlobo
- Hlooho ea hlooho ka mor'a tlhahlobo
- Hypersensitivity (alejiki) karabelo ho thethebatso
- Tšoaetso e hlahisoang ke nale e fetang letlalong
- Tšenyo ea methapo ea mokokotlo, haholo haeba motho a tsamaea nakong ea tlhahlobo
Teko ea antibody ea coccidioides - mokelikeli oa mokokotlo
CC ea Chernecky, Berger BJ. Li-coccidioides serology - mali kapa CSF. Ka: Chernecky CC, Berger BJ, bahlophisi. Liteko tsa Laboraro le Mekhoa ea Tlhatlhobo. La 6th. St Louis, MO: Elsevier Saunders; 2013: 353.
Galgiani JN. Coccidioidomycosis (Li-coccidioides mefuta). Ka: Bennett JE, Dolin R, Blaser MJ, bahlophisi. Mandell, Douglas, le Bennett's Principles and Practice of Infectious Diseases, Khatiso e Ntjhafalitsoeng. La 8th. Philadelphia, PA: Elsevier Saunders; 2015: khaolo ea 267.