Hyperthermia e kotsi

Malignant hyperthermia (MH) ke lefu le bakang ho phahama ho potlakileng ha mocheso oa 'mele le ho honyela ho matla ha mesifa ha motho ea nang le MH a fumana anesthesia ka kakaretso. MH e fetisoa ka malapa.

Hyperthermia e bolela mocheso o phahameng oa 'mele. Boemo bona ha bo tšoane le hyperthermia e tsoang maemong a tšohanyetso a bongaka a kang ho chesoa ke mocheso kapa tšoaetso.

MH e futsitsoe. Ke motsoali a le mong feela ea lokelang ho jara lefu lena hore ngoana a rue boemo boo.

E kanna ea hlaha ka mafu a mang a futsitsoeng a mesifa, joalo ka multiminicore myopathy le lefu la mantlha la mantlha.

Matšoao a MH a kenyelletsa:

• Ho tsoa mali
• Moroto o mosootho o lefifi (ka lebaka la protheine ea mesifa e bitsoang myoglobin ka morong)
• Ho opeloa ke mesifa ntle le lebaka le hlakileng, joalo ka boikoetliso kapa kotsi
• Ho satalla ha mesifa le ho satalla
• Tsoha mocheso oa 'mele ho isa ho 105 ° F (40.6 ° C) kapa ho feta

MH hangata e fumanoa kamora hore motho a fuoe moriana o thethebatsang nakong ea ho buuoa.

Ho kanna ha ba le nalane ea lelapa ea MH kapa lefu le sa hlalosoang nakong ea anesthesia.

Motho a ka ba le ho otla ha pelo kapele ebile hangata ho sa tloaelehang.

Liteko tsa MH li ka kenyelletsa:

• Lithuto tsa ho koala mali (PT, kapa nako ea prothrombin; PTT, kapa nako ea karoloana ea thromboplastin)
• Karolo ea k'hemistri ea mali, ho kenyeletsoa CK (creatinine kinase, e phahameng maling ha mesifa e senngoa nakong ea bokuli)
• Ho etsa liteko tsa lefutso ho sheba liphoso liphatseng tsa lefutso tse amanang le lefu lena
• Biopsy ea mesifa
• Myoglobin ea moroto (protheine ea mesifa)

Nakong ea sekhetho sa MH, hangata ho fanoa ka moriana o bitsoang dantrolene. Ho phuthela motho ka kobo e pholileng ho ka thusa ho fokotsa feberu le kotsi ea mathata a tebileng.

Ho boloka ts'ebetso ea liphio nakong ea sekhahla, motho a ka fumana maro ka mothapo.

Lisebelisoa tsena li ka fana ka tlhaiso-leseling e batsi ka MH:

• Mokhatlo oa Malignant Hyperthermia oa United States - www.mhaus.org
• Mokhatlo oa Naha oa Mathata a Rare - rarediseases.org/rare-diseases/malignant-hyperthermia
• Referense ea Lehae la NIH Genetics - ghr.nlm.nih.gov/condition/malignant-hyperthermia

Likarolo tse phetoang kapa tse sa alafshoang li ka baka tšenyo ea liphio. Liketsahalo tse sa sebetsanoeng li ka bolaea.

Mathata ana a tebileng a ka hlaha:

• Ho kgaola setho
• Ho senyeha ha lisele tsa mesifa
• Ho ruruha ha matsoho le maoto le mathata a phallo ea mali le ts'ebetso ea methapo (compartment syndrome)
• Lefu
• Ho koala mali le ho tsoa mali ho sa tloaelehang
• Mathata a morethetho oa pelo
• Ho hloleha ha liphio
• Sekhahla sa asiti maling a 'mele (metabolic acidosis)
• Mokelikeli o hahang ka matšoafong
• Matšoao a fokolang kapa a holofetseng (myopathy kapa muscular dystrophy)

Haeba u hloka ho buuoa, bolella ngaka ea hao e buoang le ngaka e robatsang ka lithethefatsi pele u etsoa opereishene haeba:

• Ua tseba hore uena kapa setho sa lelapa la hau le bile le mathata ka anesthesia e akaretsang
• Ua tseba hore u na le nalane ea lelapa ea MH

Ho sebelisa meriana e meng ho ka thibela mathata a MH nakong ea ts'ebetso.

Bolella mofani oa tlhokomelo ea bophelo pele u etsoa opereishene ka kakaretso ea anesthesia, haeba uena kapa mang kapa mang lelapeng la hau a na le MH.

Qoba lithethefatsi tse matlafatsang tse kang k'hok'heine, amphetamine (lebelo) le nyakallo. Lithethefatsi tsena li ka baka mathata a ts'oanang le MH ho batho ba tloaetseng boemo bona.

Ho khothaletsoa tlhabollo ea lefutso ho mang kapa mang ea nang le nalane ea lelapa ea myopathy, muscular dystrophy, kapa MH.

Hyperthermia - e kotsi; Hyperpyrexia - e kotsi; MH

Mokhatlo oa Amerika oa Mooki Anesthetists. Ho itokisetsa le ho phekola koluoa ​​e mpe ea hyperthermia: polelo ea boemo. www.aana.com/docs/default-source/practice-aana-com-web-documents-(all)/malignant-hyperthermia-crisis-preparedness-and-treatment.pdf?sfvrsn=630049b1_8. E ntlafalitsoe ka Mmesa 2018. E fihlile ka Mots'eanong 6, 2019.

Kulaylat MN, Dayton MT. Mathata a ho buoa. Ka: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Buka ea Sabiston ea Ngaka ea ho Buoa. 20th, ed. Philadelphia, PA: Elsevier; 2017: khaolo ea 12.

Zhou J, Bose D, Allen PD, Pessah IN. Malignant hyperthermia le mathata a amanang le mesifa. Ka: Miller RD, e hlophisitsoeng. Anesthesia ea Miller. La 8th. Philadelphia, PA: Elsevier Saunders; 2015: khaolo ea 43.