Teko ea Globulin

Litaba

• Teko ea globulin ke eng?
• E sebelisetsoa eng?
• Hobaneng ha ke hloka tlhahlobo ea globulin?
• Ho etsahalang nakong ea teko ea globulin?
• Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
• Na ho na le likotsi tsa tlhahlobo?
• Liphetho li bolelang?
• Litšupiso

Teko ea globulin ke eng?

Li-globulin ke sehlopha sa liprotheine tse maling a hau. Li entsoe sebeteng sa hau ke sesole sa hau sa 'mele. Li-globulin li bapala karolo ea bohlokoa ts'ebetsong ea sebete, ho koala mali le ho loants'a ts'oaetso. Hona le mefuta e mene e meholo ea li-globulin. Li bitsoa alpha 1, alpha 2, beta, le gamma. Joalo ka ha ho na le mefuta e fapaneng ea li-globulin, ho na le mefuta e fapaneng ea liteko tsa globulin. Tsena li kenyelletsa:

• Kakaretso ea liteko tsa protheine. Teko ena ea mali e metha mefuta e 'meli ea liprotheine: globulin le albin. Haeba liprotheine li le tlase, ho ka bolela hore o na le lefu la sebete kapa la liphio.
• Serum protheine electrophoresis. Teko ena ea mali e lekanya gamma globulins le liprotheine tse ling maling a hau. E ka sebelisoa ho fumana maemo a fapaneng, ho kenyeletsoa mathata a sesole sa 'mele le mofuta oa mofetše o bitsoang multiple myeloma.

Mabitso a mang bakeng sa liteko tsa globulin: Serum globulin electrophoresis, protheine kaofela

E sebelisetsoa eng?

Liteko tsa Globulin li ka sebelisoa ho thusa ho fumana maemo a fapaneng, ho kenyeletsoa:

• Tšenyo ea sebete kapa lefu
• Lefu la liphio
• Mathata a phepo e nepahetseng
• Mathata a ho itšireletsa mafung
• Mefuta e meng ea mofets'e

Hobaneng ha ke hloka tlhahlobo ea globulin?

Mofani oa hao oa tlhokomelo ea bophelo a ka odara liteko tsa globulin e le karolo ea tlhahlobo ea hau e tloaelehileng kapa ho thusa ho fumana maemo a itseng. Kakaretso ea liteko tsa protheine e ka kenyelletsoa letotong la liteko ho hlahloba hore na sebete sa hau se sebetsa hantle hakae. Liteko tsena, tse bitsoang liteko tsa ts'ebetso ea sebete, li ka laeloa haeba u le kotsing ea lefu la sebete kapa u na le matšoao a lefu la sebete, le ka kenyeletsang:

• Jaundice, boemo bo etsang hore letlalo le mahlo a hao a be bosehla
• Ho nyekeloa le ho hlatsa
• Ho hlohlona
• Mokhathala o iphetang
• Mokelikeli oa mokelikeli ka mpeng, maotong le maotong
• Ho felloa ke takatso ea lijo

Tekanyo ea serum protein electrophoresis e lekanya gamma globulins le liprotheine tse ling. Teko ena e ka laeloa ho fumana mathata a amanang le sesole sa 'mele, ho kenyelletsa:

• Maloetse
• Itšireletsa mafung a kang lupus le ramatiki ea ramatiki
• Multiple myeloma, mofuta oa mofets'e

Ho etsahalang nakong ea teko ea globulin?

Liteko tsa Globulin ke liteko tsa mali. Nakong ea tlhahlobo ea mali, setsebi sa tlhokomelo ea bophelo se tla nka sampole ea mali mothapong o letsohong la hao, a sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ha o hloke litokisetso tse khethehileng bakeng sa teko ea globulin. Haeba mofani oa hao oa tlhokomelo ea bophelo le eena a laetse liteko tse ling tsa mali, ho ka 'na ha hlokahala hore u itime lijo (u se ke ua ja kapa ua noa) lihora tse' maloa pele ho tlhahlobo. Mofani oa hao oa tlhokomelo ea bophelo o tla u tsebisa haeba ho na le litaelo tse khethehileng tseo u lokelang ho li latela.

Na ho na le likotsi tsa tlhahlobo?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.

Liphetho li bolelang?

Maemo a tlase a globulin e ka ba sesupo sa lefu la sebete kapa la liphio. Maemo a phahameng a ka supa ts'oaetso, mafu a ho ruruha kapa mathata a boits'ireletso ba mmele. Mefuta e phahameng ea globulin e ka boela ea bontša mefuta e itseng ea mofets'e, joalo ka myeloma e mengata, lefu la Hodgkin, kapa malignant lymphoma. Leha ho le joalo, liphetho tse sa tloaelehang li ka bakoa ke meriana e itseng, ho felloa ke metsi 'meleng kapa lintho tse ling. Ho ithuta hore na liphetho tsa hau li bolelang, bua le mofani oa tlhokomelo ea bophelo.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Litšupiso

1. AIDSinfo [Inthanete]. Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Gamma Globulin; [e ntlafalitsoeng 2017 Feb 2; e qotsitsoeng 2017 Feb 2]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://aidsinfo.nih.gov/education-materials/glossary/261/gamma-globulin
2. Mokhatlo oa American Cancer [Inthanete]. Atlanta: Mokhatlo oa Amerika oa Kankere Inc .; c2017. Multiple myeloma ke eng ?; [e ntlafalitsoeng 2016 Jan 19; e qotsitsoeng 2017 Feb 2]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: http://www.cancer.org/cancer/multiplemyeloma/detailedguide/multiple-myeloma-what-is-multiple-myeloma
3. Mokhatlo oa American Liver. [Inthanete]. New York: American Liver Foundation; c2017. Liteko tsa Ts'ebetso ea Sebete; [e ntlafalitsoeng 2016 Jan 25; e qotsitsoeng 2017 Feb 2]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: http://www.liverfoundation.org/abouttheliver/info/liverfunctiontests/
4. Motheo oa Khaello ea Ts'ireletso ea 'mele [Marang-rang]. Towson (MD): Motheo oa Khaello ea 'mele; c2016. Khaello ea IgA e khethiloeng [e qotsitsoeng 2017 Feb 2]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: http://primaryimmune.org/about-primary-immunodeficiencies/specific-disease-types/selective-iga-deficiency/
5. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2017. Kakaretso ea liprotheine le Albumin / Globulin (A / G); [e ntlafalitsoeng 2016; La 10 Mantaha; e qotsitsoeng 2017 Feb 2]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://labtestsonline.org/understanding/analytes/tp/tab/test/
6. McCainless C, Axel A, Slaets D, Dejoie T, Clemens P, Frans S, Bald J, Plesner T, Jacobs J, van de Donk N, Schecter J, Ahmadi T Sasser, A. Ho beha leihlo bakuli ba bangata ba myeloma ba alafshoang ka daratumumab: ho soma ho kena-kenana le monoclonal antibody. Clinical Chemistry le Laboratory Medicine (CCLM) [Inthanete]. 2016 Jun [e qotsitsoeng 2017 Feb 2]; EA-54 (6) E fumaneha ho tsoa ho: https://www.degruyter.com/view/j/cclm.2016.54.issue-6/cclm-2015-1031/cclm-2015-1031.xml
7. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Likotsi Tsa Liteko Tsa Mali ke Life ?; [e ntlafalitsoeng 2012 Jan 6; e qotsitsoeng 2017 Feb 2]; [li-skrini tse ka bang 5]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
8. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Seo u ka se lebellang ka liteko tsa mali; [e ntlafalitsoeng 2012 Jan 6; e qotsitsoeng 2017 Feb 2]; [li-skrini tse ka bang 5]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
9. O'Connell T, Horita T, Kasravi B. Ho utloisisa le ho toloka Serum Protein Electrophoresis. Ngaka ea Lelapa ea Amerika [Inthanete]. 2005 Jan 1 [e qotsitsoeng ka 2017 Feb 2]; 71 (1): 105–112. E fumaneha ho tsoa ho: http://www.aafp.org/afp/2005/0101/p105.html
10. Setsi sa Johns Hopkins Lupus [Marang-rang]. Bongaka ba Johns Hopkins; c2017. Phanele ea Khemistri ea Mali [e qotsitsoeng ka 2017 Feb 2]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.hopkinslupus.org/lupus-tests/screening-laboratory-tests/blood-chemistry-panel/
11. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Univesithi ea Florida; c2017. Serum globulin electrophoresis; [e qotsitsoeng 2017 Feb 2]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/serum-globulin-electrophoresis
12. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2017. Health Encyclopedia: Protheine Electrophoresis (Mali); [e qotsitsoeng 2017 Feb 2]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=protein_electrophoresis_serum
13. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2017. Health Encyclopedia: Kakaretso ea liprotheine le karolelano ea A / G; [e qotsitsoeng 2017 Feb 2]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=total_protein_ag_ratio

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.