Tsamaiso e mengata ea atrophy - cerebellar subtype

Multiple system atrophy - cerebellar subtype (MSA-C) ke lefu le sa tloaelehang le bakang libaka tse tebileng bokong, kaholimo ho mokokotlo, ho fokotseha (atrophy). MSA-C e ne e tsejoa e le olivopontocerebellar atrophy (OPCA).

MSA-C e ka fetisoa ka malapa (mofuta o futsitsoeng). E ka ama le batho ba se nang nalane e tsebahalang ea lelapa (foromo e sa tloaelehang).

Bafuputsi ba fumane liphatsa tse ling tsa lefutso tse amehang mofuteng o futsitsoeng oa boemo bona.

Lebaka la MSA-C ho batho ba nang le mofuta o sa tloaelehang ha le tsejoe. Lefu lena le ntse le mpefala butle-butle (le tsoela pele).

MSA-C e atile haholo ho banna ho feta basali. Karolelano ea lilemo tsa ho qala ke lilemo tse 54.

Matšoao a MSA-C a tloaetse ho qala a le monyane ho batho ba nang le sebopeho se futsitsoeng. Letšoao le ka sehloohong ke ho tsieleha (ataxia) e ntseng e mpefala butle butle. Ho kanna ha ba le mathata ka teka-tekano, ho se bue hantle, le ho tsamaea ka thata.

Matšoao a mang a kenyeletsa:

• Ho sisinyeha ho sa tloaelehang ha mahlo
• Mekhatlo e sa tloaelehang
• Mathata a mala kapa a senya
• Ho thata ho koenya
• Matsoho le maoto a batang
• Hlooho e bobebe ha e eme
• Ho opeloa ke hlooho ha u eme hoo ho imolohile ka ho paqama
  
• Ho thatafala ha mesifa kapa ho ba thata, liphasms, ho thothomela
• Tšenyo ea methapo (neuropathy)
• Mathata a ho bua le ho robala ka lebaka la likhahla tsa methapo ea lentsoe
• Mathata a ts'ebetso ea thobalano
• Mofufutso o sa tloaelehang

Ho hlokahala tlhahlobo e phethahetseng ea bongaka le ea methapo, hammoho le tlhahlobo ea matšoao le nalane ea lelapa ho etsa hore motho a fumanoe.

Ho na le liteko tsa lefutso ho sheba lisosa tsa mefuta e meng ea lefu lena. Empa, ha ho na tlhahlobo e ikhethang e fumanehang maemong a mangata. MRI ea boko e ka bonts'a liphetoho ka boholo ba likarolo tsa boko tse amehileng, haholoholo ha lefu lena le ntse le mpefala. Empa ho a khonahala ho ba le bothata mme o be le MRI e tloaelehileng.

Liteko tse ling tse kang positron emission tomography (PET) li kanna tsa etsoa ho hlakola maemo a mang. Tsena li ka kenyelletsa lithuto tsa ho koenya ho bona hore na motho a ka koenya lijo le mokelikeli ka mokhoa o sireletsehileng.

Ha ho na kalafo kapa pheko e khethehileng bakeng sa MSA-C. Morero ke ho phekola matšoao le ho thibela mathata. Sena se ka kenyelletsa:

• Meriana ea ho thothomela, e kang ea lefu la Parkinson
• Puo, kalafo ea mosebetsing le ea 'mele
• Litsela tsa ho thibela ho bipetsana
• Lithuso tsa ho tsamaea ho thusa ka tekatekano le ho thibela ho oa

Lihlopha tse latelang li ka fana ka lisebelisoa le tšehetso ho batho ba nang le MSA-C:

• Hlōla Alliance ea MSA - conqumsa.org/patient-programs/
• Mokhatlo oa MSA - www.multiplesystematrophy.org/msa-resource/

MSA-C e mpefala butle-butle, 'me ha ho na pheko. Ka kakaretso pono e fosahetse. Empa, ho ka nka lilemo pele motho e mong a holofetse haholo.

Mathata a MSA-C a kenyelletsa:

• Ho bipetsa
• Tšoaetso ea ho hema lijo ka matšoafong (pneumonia ea aspiration)
• Kotsi ea ho oa
• Mathata a phepo e nepahetseng ka lebaka la bothata ba ho koenya

Bitsa mofani oa tlhokomelo ea bophelo haeba u na le matšoao a MSA-C. U tla hloka ho bonoa ke ngaka ea methapo. Sena ke ngaka e sebetsanang le mathata a tsamaiso ea methapo.

MSA-C; Cerebellar multiple system atrophy; Olivopontocerebellar felloa ke matla; OPCA; Ho senyeha ha Olivopontocerebellar

• Sisteme ea methapo e bohareng le methapo ea methapo

Ciolli L, Krismer F, Nicoletti F, Wenning GK. Nchafatso ho cerebellar subtype ea multiple system atrophy. Cerebellum Ataxias. 2014; 1-14. PMID: 26331038 phatlalatsoa.ncbi.nlm.nih.gov/26331038/.

Gilman S, Wenning GK, Low PA, le al. Polelo ea bobeli ea tumellano mabapi le ts'oaetso ea multiple atrophy system. Neurology. 2008; 71 (9): 670-676. PMID: 18725592 phatlalalitsoe.ncbi.nlm.nih.gov/18725592/.

Lefu la Jancovic J. Parkinson le mathata a mang a motsamao. Ka: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, bahlophisi. Neurology ea Bradley ho Tloaelo ea Bongaka. La 7th. Philadelphia, PA: Elsevier; 2016: khaolo ea 96.

Ma MJ. Biopsy pathology ea mathata a neurodegenerative ho batho ba baholo. Ka: Perry A, DJ oa Brat, li-eds. Mokhoa o sebetsang oa ho buoa ka Neuropathology: Mokhoa oa ho Itlhahloba. Lekhetlo la bobeli. Philadelphia, PA: Elsevier, 2018: khaolo ea 27.

Walsh RR, Krismer F, Galpern WR, le al. Litlhahiso tsa kopano ea lefatše ka bophara ea patlisiso ea atrophy ea lipatlisiso. Neurology. 2018; 90 (2): 74-82. PMID: 29237794 pubmed.ncbi.nlm.nih.gov/29237794/.