Ho tsebahala ha lipoprotein lipase

Ho haella ha lipoprotein lipase ke sehlopha sa mathata a sa tloaelehang a liphatsa tsa lefutso moo motho a hlokang protheine e hlokahalang ho senya limolek'hule tsa mafura. Boloetse bona bo baka mafura a mangata ho ahela maling.

Ho haella ha lipoprotein lipase ho tloaelehileng ho bakoa ke lefutso le sa sebetseng le fetisoang ke malapa.

Batho ba nang le boemo bona ha ba na enzyme e bitsoang lipoprotein lipase. Ntle le enzyme ena, 'mele o ke ke oa senya mafura a tsoang lijong tse sililoeng. Likaroloana tsa mafura tse bitsoang li-chylomicrons li aha maling.

Lisosa tsa kotsi li kenyelletsa nalane ea lelapa ea khaello ea lipoprotein lipase.

Boemo bona hangata bo bonoa pele bongoaneng kapa bongoaneng.

Matšoao a ka kenyelletsa efe kapa efe ea tse latelang:

• Mahlaba a mpeng (a ka bonahala e le colic ho masea)
• Ho felloa ke takatso ea lijo
• Ho nyekeloa ke pelo, ho hlatsa
• Bohloko ba mesifa le masapo
• Ho eketsa sebete le spleen
• Ho hloleha ho atleha maseeng
• Mafura a boloka letlalo (xanthomas)
• Maemo a phahameng a triglyceride maling
• Li-retina tse phaleng le methapo ea mali e mebala e tšoeu ka har'a li-retina
• Ho ruruha ho sa feleng ha manyeme
• Bosehla ba mahlo le letlalo (jaundice)

Mofani oa tlhokomelo ea bophelo o tla etsa tlhahlobo ea 'mele' me a botse ka matšoao.

Ho tla etsoa liteko tsa mali ho lekola li-cholesterol le triglyceride. Ka linako tse ling, ho etsoa tlhahlobo e khethehileng ea mali kamora hore o fuoe tšesaane tsa mali ka mothapo. Teko ena e sheba mesebetsi ea lipoprotein lipase maling a hau.

Liteko tsa lefutso li ka etsoa.

Kalafo e ikemiselitse ho laola matšoao le maemo a triglyceride ea mali ka phepo e fokolang haholo. Mofani oa hau o tla khothaletsa hore o se ke oa ja ligrama tse fetang 20 tsa mafura ka letsatsi ho thibela matšoao hore a se ke a khutla.

Ligrama tse mashome a mabeli tsa mafura li lekana le e 'ngoe ea tse latelang:

• Likhalase tse peli tsa 8-ounce (240 milliliters) tsa lebese le felletseng
• Di-teaspoon tse 4 (9.5 grams) tsa majarine
• Li-ounces tse 113 tsa nama ea nama

Lijo tse tloaelehileng tsa Amerika li na le mafura a ka bang 45% ea likhalori tsohle. Ho khothalletsoa livithamini tse nang le mafura a nang le mafura A, D, E, le K le liminerale bakeng sa batho ba jang lijo tse se nang mafura haholo. U kanna ua batla ho bua ka litlhoko tsa hau tsa lijo le mofani oa hau le setsebi sa phepo e nepahetseng.

Pancreatitis e amanang le khaello ea lipoprotein lipase e arabela kalafong ea lefu leo.

Lisebelisoa tsena li ka fana ka tlhaiso-leseling e batsi ka khaello ea lipoprotein lipase ea malapa:

• Mokhatlo oa Naha oa Mathata a Rare - rarediseases.org/rare-diseases/familial-lipoprotein-lipase-deficiency
• Referense ea Lehae la NIH Genetics - ghr.nlm.nih.gov/condition/familial-lipoprotein-lipase-deficiency

Batho ba nang le boemo bona ba latelang lijo tse mafura haholo ba ka phela ho fihlela ba le batho ba baholo.

Pancreatitis le linako tse tloaelehileng tsa bohloko ba mpeng li ka hlaha.

Hangata Xanthomas ha e utloise bohloko ntle le haeba e hohla haholo.

Bitsa mofani oa hau bakeng sa ho hlahloba haeba motho e mong ka lapeng la hau a na le khaello ea lipoprotein lipase. Ho khothaletsoa tlhabollo ea lefutso ho mang kapa mang ea nang le nalane ea lelapa ea lefu lena.

Ha ho na thibelo e tsebahalang ea lefu lena le sa tloaelehang, le futsitsoeng. Ho hlokomela likotsi ho ka lumella ho fumanoa kapele. Ho latela lijo tse mafura haholo ho ka ntlafatsa matšoao a lefu lena.

Mofuta oa I hyperlipoproteinemia; Tloaelehileng chylomicronemia; Khaello ea LPL e tloaelehileng

• Boloetse ba methapo ea mali

Genest J, Libby P. Lipoprotein mathata le lefu la pelo. Ka: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Lefu la pelo la Braunwald: Buka ea bongaka ea meriana ea pelo. 11th ed. Philadelphia, PA: Elsevier; 2019: khaolo ea 48.

Semenkovich CF, Goldberg AC, Goldberg IJ. Mathata a metabolism ea lipid. Ka: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, bahlophisi. Buka ea Williams ea Endocrinology. 13th ed. Philadelphia, PA: Elsevier; 2016: khaolo ea 37.