Sengoli: William Ramirez
Letsatsi La Creation: 24 September 2021
Ntlafatsa Letsatsi: 13 November 2024
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Liver cholestasis   causes, symptoms, diagnosis, treatment & pathology
Video: Liver cholestasis causes, symptoms, diagnosis, treatment & pathology

Cholestasis ke boemo bofe kapa bofe moo phallo ea bile e tsoang sebeteng e liehang kapa e thibetsoeng.

Ho na le lisosa tse ngata tsa cholestasis.

Extrahepatic cholestasis e hlaha kantle ho sebete. E ka bakoa ke:

  • Lihlahala tsa mokokotlo oa metsi
  • Likokoana-hloko
  • Ho fokotsa mokokotlo oa bile
  • Majoe ka mokoting o tloaelehileng oa bile
  • Pancreatitis
  • Hlahala ea Pancreatic kapa pseudocyst
  • Khatello ea methapo ea bile ka lebaka la boima kapa hlahala e haufi
  • Sclerosing cholangitis ea mantlha

Intrahepatic cholestasis e hlaha kahare ho sebete. E ka bakoa ke:

  • Lefu la sebete la joala
  • Amyloidosis
  • Bacteria abscess sebeteng
  • Ho feptjoa feela ka methapo (IV)
  • Lymphoma
  • Boimana
  • Cirrhosis ea mantlha ea biliary
  • Kankere ea pele kapa ea metastatic ea kankere
  • Sclerosing cholangitis ea mantlha
  • Sarcoidosis
  • Matšoao a tebileng a hasaneng ka mali (sepsis)
  • Lefuba
  • Hepatitis ea vaerase

Meriana e meng e ka baka cholestasis, ho kenyelletsa:


  • Lithibela-mafu, tse kang ampicillin le li-penicillin tse ling
  • Li-steroids tsa Anabolic
  • Lipilisi tsa thibelo ea bokhachane
  • Chlorpromazine
  • Cimetidine
  • Estradiol
  • Imipramine
  • Prochlorperazine
  • Terbinafine
  • Tolbutamide

Matšoao a ka kenyelletsa:

  • Litulo tsa 'mala oa letsopa kapa tse tšoeu
  • Moroto o lefifi
  • Ho hloleha ho sila lijo tse itseng
  • Ho hlohlona
  • Ho nyekeloa kapa ho hlatsa
  • Bohloko karolong e kaholimo ea mpa
  • Letlalo le mosehla kapa mahlo

Liteko tsa mali li ka bonts'a hore u phahamisitse bilirubin le alkaline phosphatase.

Ho sebelisoa liteko tsa ho lekola boemo bona. Liteko li kenyelletsa:

  • CT scan ea mpa
  • MRI ea mpa
  • Endoscopic retrograde cholangiopancreatography (ERCP), e ka tseba sesosa
  • Ultrasound ea mpa

Sesosa sa cholestasis se tlameha ho phekoloa.

Hore na motho o sebetsa hantle hakae ho latela lefu le bakang boemo boo. Majoe ka har'a pitsa e tloaelehileng ea bile a ka tlosoa hangata. Sena se ka phekola cholestasis.


Li-stents li ka beoa libakeng tse bulehileng tsa pompo e tloaelehileng ea bile e fokotsitsoeng kapa e koetsoeng ke mofetše.

Haeba boemo bo bakoa ke tšebeliso ea moriana o itseng, hangata o tla fela ha o khaotsa ho noa moriana oo.

Mathata a ka kenyelletsa:

  • Letšollo
  • Ho hloleha ha 'mele ho ka etsahala haeba sepsis e hlaha
  • Ho monya mafura a livithamini tse nang le mafura
  • Ho hlohlona ho matla
  • Masapo a fokolang (osteomalacia) ka lebaka la ho ba le cholestasis nako e telele haholo

Bitsa mofani oa tlhokomelo ea bophelo haeba u na le:

  • Ho hlohlona ho sa feleng
  • Letlalo le mosehla kapa mahlo
  • Matšoao a mang a cholestasis

Fumana ente bakeng sa hepatitis A le B haeba u le kotsing. Se ke oa sebelisa lithethefatsi tse kenang methapong 'me ua arolelana linalete.

Cholestasis ea ka hare; Extrahepatic cholestasis

  • Majoe a majoe
  • Sefuba
  • Sefuba

Eaton JE, Lindor KD. Motsoako oa mantlha oa biliary cholangitis. Ka: Feldman M, Friedman LS, Brandt LJ, bahlophisi. Sleisenger le Mafu a ka Mpeng le a Fordtran. 11th ed. Philadelphia, PA: Elsevier; 2021: khaolo ea 91.


Fogel EL, Sherman S. Maloetse a gallbladder le bile ducts. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 146.

Lidofsky SD. Jaundice. Ka: Feldman M, Friedman LS, Brandt LJ, bahlophisi. Sleisenger le Fordtran's Mpeng le Mafu a Sebete. 11th ed. Philadelphia, PA: Elsevier; 2021: khaolo ea 21.

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