Neutropenia: hore na ke eng le lisosa tsa mantlha

Litaba

• Lisosa tsa neutropenia
• Cyclic neutropenia
• Febrile neutropenia

Neutropenia e tšoana le ho fokotseha ha palo ea li-neutrophil, e leng lisele tsa mali tse ikarabellang bakeng sa ho loants'a mafu. Ha e le hantle, palo ea li-neutrophil e lokela ho ba lipakeng tsa 1500 le 8000 / mm³, leha ho le joalo, ka lebaka la liphetoho mokong oa masapo kapa ts'ebetsong ea ho butsoa ha lisele tsena, palo ea li-neutrophil tse potolohang e ka fokotseha, e khethollang neutropenia.

Ho latela palo ea li-neutrophil tse fumanoeng, neutropenia e ka aroloa ho latela boima ba eona ho:

• Neutropenia e bonolo, moo li-neutrophil li pakeng tsa 1000 le 1500 / µL;
• Neutropenia e itekanetseng, moo li-neutrophils li pakeng tsa 500 le 1000 / µL;
• Neutropenia e matla, moo li-neutrophils li leng ka tlase ho 500 / µL, tse ka khahlisang ho ata ha li-fungus le libaktheria tse phelang ka tlhaho 'meleng, tse bakang tšoaetso;

Ha li-neutrophil tse potoloha li le nyane, monyetla oa hore motho a tšoaetsoe ke mafu o kholoanyane. Ho bohlokoa hore neutropenia e hlahlojoe ka hloko, hobane sephetho se kanna sa susumetsoa ke mathata ka nako ea pokello, sampole ea polokelo kapa liphetoho ho lisebelisoa tseo tlhahlobo e etsoang ho tsona, mohlala. Ka hona, ho kgothaletswa hore palo e felletseng ea neutrophil e hlahlojoe ho bona hore na ehlile ho na le neutropenia.

Ntle le moo, ha palo ea lisele tse khubelu tsa mali le liplatelete e le tloaelehileng 'me palo ea li-neutrophil e le tlase, ho kgothaletswa hore lipalo tsa mali tse phetoang li etsoe ho netefatsa neutropenia.

Lisosa tsa neutropenia

Phokotso ea li-neutrophil e kanna ea ba ka lebaka la tlhahiso e sa lekanang kapa liphetoho ts'ebetsong ea ho butsoa ha li-neutrophil mokong oa masapo kapa ka lebaka la sekhahla se phahameng sa ts'enyo ea li-neutrophil maling. Kahoo, lisosa tsa mantlha tsa neutropenia ke:

• Phokolo ea mali ea Megaloblastic;
• Khaello ea mali khafetsa;
• Lefuemia;
• Spleen e atolositsoeng;
• Ho thatafala ha sebete;
• Tsamaiso ea lupus erythematosus;
• Paroxysmal bosiu hemoglobinuria;
• Ts'oaetso ea vaerase, haholo-holo ke vaerase ea Epstein-Barr le vaerase ea hepatitis;
• Tšoaetso ea baktheria, haholo ha ho na le lefuba le septicemia.

Ntle le moo, neutropenia e ka hlaha ka lebaka la kalafo ka meriana e meng, joalo ka Aminopyrine, Propiltiouracil le Penicillin, mohlala, kapa ka lebaka la khaello ea vithamine B12 kapa folic acid, mohlala.

Ithute haholoanyane ka li-neutrophils.

Cyclic neutropenia

Cyclic neutropenia e tsamaellana le lefu la autosomal le hlahelletseng la lefutso le khetholloang ke ho fokotseha ha li-neutrophil ka lipotoloho, ke hore, matsatsi a mang le a mang a 21, boholo ba nako, ho na le phokotso ea palo ea li-neutrophil tse potolohang.

Lefu lena ha le fumanehe hangata 'me le hlaha ka lebaka la phetoho ea liphatsa tsa lefutso tsa chromosome 19 e ikarabellang bakeng sa tlhahiso ea enzyme, elastase, li-neutrophils. Ha ho sena enzyme ena, li-neutrophil li senyeha khafetsa.

Febrile neutropenia

Febrile neutropenia e hlaha ha ho na le li-neutrophil tse nyane, hangata li le ka tlase ho 500 / µL, e khahlisang ketsahalo ea tšoaetso mme e lebise keketsehong ea mocheso oa 'mele, hangata e kaholimo ho 38ºC.

Ka hona, kalafo ea febrile neutropenia e kenyelletsa ho noa lithethefatsi tse theolang feberu, lithibela-mafu ka molomo kapa ka methapong, ho latela seo ngaka e u joetsang sona ho laola ts'oaetso le liente tse nang le lintlha tsa kholo ea neutrophil, ho loants'a neutropenia. Ntle le moo, ho kanna ha hlokahala hore ho eketsoe moriana oa bobeli oa likokoana-hloko kalafong haeba mokuli a tsoelapele ho ba le feberu kamora matsatsi a 5 a ho qala kalafo.