Ke eng mosaic le litlamorao tsa eona tsa mantlha

Litaba

• Lintlha tse ka sehloohong
• Liphello tsa mosai

Mosaicism ke lebitso le fuoeng mofuta oa ho hloleha hoa liphatsa tsa lefutso nakong ea kholo ea popelo kahare ho popelo ea bo-mme, moo motho a qalang ho ba le lisebelisoa tse peli tse fapaneng tsa lefutso, e leng se entsoeng ka mateano a lehe le peo ea botona ea batsoali. , le e 'ngoe e hlahang ka lebaka la phetoho ea sele ha ho hola.

Kahoo, motho o tla hlahisa motsoako oa lisele, ka liperesente tsa lisele tse tloaelehileng le liperesente tse ling tsa lisele tse nang le phetoho, joalo ka ha ho bonts'itsoe setšoantšong se latelang:

Lintlha tse ka sehloohong

Mosaicism e etsahala ha phetoho e hlaha ka seleng ea lesea le sa tsoa emoloa, hangata ke tahlehelo kapa ho ipheta ha chromosome, e etsang hore motho a hlahise 'mele oa hae ka mefuta e 2 ea lisele le mefuta e 2 ea liphatsa tsa lefutso. Phetoho ena e ka ba ea mefuta e 'meli:

• Ho hlahisa limela kapa Gonadal: e ama peo kapa mahe, ka liphetoho tse ka fetisetsoang baneng. Mehlala e meng ea mafu a bakoang ke liphetoho liseleng tsa kokoana-hloko ke Turner's syndrome, osteogenesis e sa phethahalang le Duchenne muscular dystrophy;
• Somatics: moo lisele tse tsoang karolong efe kapa efe ea 'mele li nang le phetoho ena, hore na motho a ka ba le liphetoho mmeleng tse bakoang ke eona kapa che. Kahoo, ponahalo ea 'mele ea phetoho e ipapisitse le hore na ho ameha lisele life' meleng le tse kae 'meleng. Sesomatic mosaic e ka fetisoa ho tloha ho batsoali ho ea ho bana, 'me mehlala e meng ea mafu a bakoang ke Down's syndrome le neurofibromatosis.

Ka lehlakoreng le leng, mosaic e tsoakaneng e etsahala ha motho a e-na le mefuta e 'meli ea mosaic, tse hlahisang limela le tse ling.

Mosaicism e fapane le chimerism ka hore, boemong bona, liphatsa tsa lefutso tsa lesea le sa tsoa emoloa li kopitsoa ke ho kopanya mahe a mabeli a fapaneng, a fetohang a le mong. Ithute haholoanyane ka boemo bona ka ho chesa.

Liphello tsa mosai

Le ha linyeoe tse ngata tsa mosai li sa bake matšoao kapa litlamorao bakeng sa bophelo bo botle ba motho, boemo bona bo ka baka mathata le mafu a 'maloa ho motho ea tsamaisang thepa,' me mehlala e meng ke ena:

• Khethollo ea kankere;
• Liphetoho kholong;
• Khethollo ea pele ea ho ntša mpa ka boithatelo;
• Liphetoho mokhoeng oa 'mala oa letlalo;
• Ocular heterochromia, moo motho a ka bang le leihlo le le leng la 'mala o mong le o mong;
• Lefu la Down;
• Turner lefu;
• Osteogenesis imperfecta;
• Ho fokola ha mesifa ea Duchenne;
• Li-syndromes tsa McCune-Albright;
• Lefu la Pallister-Killian;
• Lefu la Proteus.

Ntle le moo, ho hlokometsoe hore mosaicism e eketsa monyetla oa ho kula maloetse a methapo, joalo ka Alzheimer's kapa Parkinson, ka mohlala.