Teko ea Isoenzymes ea Lactate Dehydrogenase (LDH)

Litaba

• Teko ea isoenzymes ea lactate dehydrogenase (LDH) ke eng?
• E sebelisetsoa eng?
• Hobaneng ha ke hloka tlhahlobo ea LDH isoenzymes?
• Ho etsahalang nakong ea tlhahlobo ea LDH isoenzymes?
• Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
• Na ho na le likotsi tsa tlhahlobo?
• Liphetho li bolelang?
• Litšupiso

Teko ea isoenzymes ea lactate dehydrogenase (LDH) ke eng?

Teko ena e lekanya boemo ba li-isoenzymes tse fapaneng tsa lactate dehydrogenase (LDH) maling. LDH, e tsejoang hape e le lactic acid dehydrogenase, ke mofuta oa protheine, e tsejoang e le enzyme. LDH e bapala karolo ea bohlokoa ho etseng matla a 'mele oa hau. E fumanoa hoo e batlang e le lisele tsohle tsa 'mele.

Hona le mefuta e mehlano ea LDH. Li tsejoa e le isoenzymes. Li-isoenzymes tse hlano li fumaneha ka bongata bo fapaneng lithong tsa 'mele.

• LDH-1: e fumanoang liseleng tsa pelo le tse khubelu tsa mali
• LDH-2: e fumanoa lisele tse tšoeu tsa mali. E boetse e fumanoa liseleng tsa pelo le tse khubelu tsa mali, empa e le nyane ho feta LDH-1.
• LDH-3: e fumanoa lisele tsa matšoafo
• LDH-4: e fumanoa lisele tse tšoeu tsa mali, lisele tsa liphio le liphakaretsi le li-lymph node
• LDH-5: e fumanoa sebeteng le mesifa ea masapo

Ha lisele li senyehile kapa li kula, li ntša isoenzymes ea LDH maling. Mofuta oa LDH isoenzyme e lokollotsoeng ho latela hore na ke lisele life tse senyehileng. Teko ena e ka thusa mofani oa hau ho fumana sebaka le sesosa sa tšenyo ea lisele tsa hau.

Mabitso a mang: LD isoenzyme, lactic dehydrogenase isoenzyme

E sebelisetsoa eng?

Ho sebelisoa teko ea LDH isoenzymes ho fumana sebaka, mofuta le boima ba tšenyo ea lisele. E ka thusa ho fumana maemo a fapaneng a kenyeletsang:

• Tlhaselo ea pelo ea morao tjena
• Khaello ea mali
• Lefu la liphio
• Lefu la sebete, ho kenyelletsa lefu la sebete le lefu la ho thatafala ha sebete
• Embolism ea pulmonary, mali a sokelang bophelo matšoafong

Hobaneng ha ke hloka tlhahlobo ea LDH isoenzymes?

U kanna oa hloka tlhahlobo ena haeba mofani oa tlhokomelo ea bophelo a belaela hore o na le tšenyo ea lisele ho latela matšoao a hau le / kapa liteko tse ling. Hangata tlhahlobo ea LDH isoenzymes e etsoa e le ho latela tlhahlobo ea lactate dehydrogenase (LDH). Teko ea LDH e boetse e lekanya maemo a LDH, empa ha e fane ka tlhaiso-leseling ka sebaka kapa mofuta oa tšenyo ea lisele.

Ho etsahalang nakong ea tlhahlobo ea LDH isoenzymes?

Ngaka ea tlhokomelo ea bophelo e tla nka sampole ea mali mothapong o letsohong la hao, e sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ha o hloke litokisetso tse khethehileng bakeng sa tlhahlobo ea LDH isoenzymes.

Na ho na le likotsi tsa tlhahlobo?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.

Liphetho li bolelang?

Haeba liphetho tsa hau li bonts'itse hore maemo a le leng kapa a mang a li-isoenzymes tsa LDH a ne a sa tloaeleha, mohlomong ho bolela hore o na le mofuta oa lefu la lisele kapa tšenyo. Mofuta oa lefu kapa tšenyo e tla itšetleha ka hore na li-isoenzymes tsa LDH li na le maemo a sa tloaelehang. Mathata a bakang maemo a sa tloaelehang a LDH a kenyelletsa:

• Khaello ea mali
• Lefu la liphio
• Lefu la sebete
• Kotsi ea mesifa
• Lefu la pelo
• Pancreatitis
• Mononucleosis e tšoaetsanoang (mono)

Haeba u na le lipotso mabapi le liphetho tsa hau, bua le mofani oa tlhokomelo ea bophelo.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Litšupiso

1. Hinkle J, Cheever K. Brunner & Suddarth's Handbook ea Liteko tsa Laboraro le Tlhatlhobo. 2nd Ed, mosa. Philadelphia: Wolters Kluwer Bophelo, Lippincott Williams & Wilkins; c2014. Lactate Dehydrogenase; leq. EA-354-TK
2. Bophelo ba Bana ho tsoa Nemours [Marang-rang]. Jacksonville (FL): Motheo oa Nemours; c1995–2019. Teko ea Mali: Lactate Dehydrogenase (LDH) [e qotsitsoeng ka la 3 Phupu 3]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://kidshealth.org/en/parents/test-ldh.html
3. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC; Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2019. Lactate Dehydrogenase (LD) [e ntlafalitsoeng 2018 Dec 20; e qotsitsoeng ka la 9 Phupu 3]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/lactate-dehydrogenase-ld
4. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liteko tsa Mali [e bontšitsoeng ka la 3 Phupu 3]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
5. Papadopoulos NM. Likopo tsa bongaka tsa Lactate Dehydrogenase Isoenzymes. Ann Clin Lab Sci [Inthanete]. 1977 Nov-Dec [e qotsitsoeng ka 2019 Phupu 3]; 7 (6): 506-510. E fumaneha ho tsoa ho: http://www.annclinlabsci.org/content/7/6/506.full.pdf
6. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Gainesville (FL): Univesithi ea Florida Health; c2019. Teko ea mali ea LDH isoenzyme: Kakaretso [e ntlafalitsoeng 2019 Jul 3; e qotsitsoeng ka la 9 Phupu 3]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/ldh-isoenzyme-blood-test
7. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2019. Health Encyclopedia: Lactate Dehydrogenase Isoenzymes [e qotsitsoeng ka la 3 Phupu 3]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=lactate_dehydrogenase_isoenzymes
8. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2019. Health Encyclopedia: Pulmonary Embolism [e qotsitsoeng ka la 3 Phupu 3]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=85&contentid=p01308

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.