Sengoli: Roger Morrison
Letsatsi La Creation: 28 September 2021
Ntlafatsa Letsatsi: 10 Pherekhong 2025
Anonim
Recombinant human interferon alfa 2A: ke eng le hore na u ka e nka joang - Bophelo
Recombinant human interferon alfa 2A: ke eng le hore na u ka e nka joang - Bophelo

Litaba

Recombinant human interferon alpha 2a ke protheine e bonts'itsoeng bakeng sa kalafo ea mafu a kang leukemia e nang le boea bo bongata, myeloma e mengata, e seng Hodgkin's lymphoma, lefu le sa foleng la myeloid leukemia, lefu la sebete le sa foleng la hepatitis C, lefu le bohloko la lefu la hepatitis C le acuminate condyloma.

Ho nahanoa hore pheko ena e sebetsa ka ho thibela ho pheta-pheta ha vaerase le ho matlafatsa karabelo ea 'mele ea moamoheli, ka ho etsa joalo e loants'a likokoana-hloko.

Mokhoa oa ho sebelisa

Recombinant human interferon alfa 2A e lokela ho fuoa ke setsebi sa tlhokomelo ea bophelo, se tla tseba ho lokisetsa moriana. Litekanyo li ipapisitse le lefu le lokelang ho phekoloa:

1. Leukemia ea sele e nang le moriri

Tekanyo e khothalletsoang ea letsatsi le letsatsi ea lithethefatsi ke 3 MIU bakeng sa libeke tse 16 ho isa ho tse 20, e fanoang e le ente e entang ka hare ho 'mele. Ho kanna ha hlokahala hore ho fokotsoe lethal dose kapa makhetlo a liente e le ho fumana palo e phahameng ea mamello. Tekanyo e khothalletsoang ea tlhokomelo ke 3 MIU, makhetlo a mararo ka beke.


Ha litla-morao li le matla, ho ka hlokahala ho fokotsa lethal dose ka halofo 'me ngaka e tlameha ho etsa qeto ea hore na motho o lokela ho tsoela pele kalafo kamora likhoeli tse tšeletseng tsa kalafo.

2. Myeloma e mengata

Tekanyo e khothalletsoang ea "interferon alfa 2A" ea motho e kopantsoeng ke 3 MIU, makhetlo a mararo ka beke, e tsamaisoang joalo ka ente ea ente kapa ea methapo e menyane. Ho latela karabelo le mamello ea motho, lethal dose le ka nyoloha hanyane ka hanyane ho fihlela ho 9 MIU, hararo ka beke.

3. Non-Hodgkin's lymphoma

Maemong a batho ba nang le lymphoma eo eseng ea Hodgkin, sethethefatsi sena se ka fuoa libeke tse 4 ho isa ho tse 6 kamora chemotherapy mme tekanyetso e khothalletsoang ke 3 MIU, makhetlo a mararo ka beke bonyane libeke tse 12, ka tsela e potileng. Ha e fanoa hammoho le chemotherapy, tekanyetso e khothalletsoang ke 6 MIU / m2, e tsamaisoang ka tsela e potileng kapa ka entramuscularly nakong ea chemotherapy ea matsatsi a 22 ho isa ho a 26.

4. Lefuemia e sa foleng ea myeloid

Lethal dose ea recombinant human interferon alfa 2A e ka nyoloha hanyane ka hanyane ho tloha ho 3 MIU ka letsatsi matsatsi a mararo ho isa ho 6 MIU ka letsatsi matsatsi a mararo ho fihlela tekanyong ea 9 MIU letsatsi le letsatsi ho fihlela qetellong ea nako ea kalafo. Kamora kalafo ea libeke tse 8 ho isa ho tse 12, bakuli ba nang le karabelo ea haematological ba ka tsoelapele kalafo ho fihlela ba arabela ka botlalo kapa likhoeli tse 18 ho isa ho tse 2 kamora ho qala kalafo.


5. Hepatitis B e sa foleng

Tekanyo e khothalletsoang batho ba baholo ke 5 MIU, makhetlo a mararo ka beke, e tsamaisoang ka tlase ho likhoeli tse 6. Bakeng sa batho ba sa arabeleng recombinant human interferon alpha 2A kamora khoeli ea kalafo, ho ka hlokahala ho eketseha ha lethal dose.

Haeba, kamora 'kalafo ea likhoeli tse 3, ho se karabo ho tsoa ho mokuli, ho khaotsa kalafo ho lokela ho tsotelloa.

6. Hepatitis C e matla le e sa foleng

Tekanyo e khothalletsoang ea interferon alfa 2A ea motho ea phekolang ke 3 ho ea ho 5 MIU, makhetlo a mararo ka beke, e tsamaisoang ka tsela e tsamaeang ka tlas'a metsi kapa ka intramuscularly ka likhoeli tse 3. Tekanyo e khothalletsoang ea tlhokomelo ke 3 MIU, makhetlo a mararo ka beke likhoeli tse 3.

7. Condylomata acuminata

Tekanyo e khothalletsoang ke ts'ebeliso ea subcutaneous kapa intramuscular ea 1 MIU ho 3 MIU, makhetlo a 3 ka beke, bakeng sa likhoeli tse 1 ho isa ho tse 2 kapa 1 MIU e sebelisitsoeng botlaaseng ba sebaka se amehileng ka matsatsi a mang, bakeng sa libeke tse 3 tse latellanang.

Ke mang ea sa lokelang ho sebelisa

Moriana ona ha oa lokela ho sebelisoa ho batho ba nang le khatello ea kelello ho eng kapa eng ea likarolo tse teng ka har'a foromo, ba nang le bokuli kapa nalane ea lefu le matla la pelo, liphio kapa sebete.


Ntle le moo, ha ea lokela ho sebelisoa ho basali ba nang le bakhachane kapa ba anyesang, ntle le haeba ba khothalletsoa ke ngaka.

Litla-morao tse ka bang teng

Litla-morao tse atisang ho hlaha ka ts'ebeliso ea meriana ena ke matšoao a kang a feberu, joalo ka mokhathala, feberu, ho hatsela, bohloko ba mesifa, hlooho, bohloko ba manonyeletso, ho fufuleloa, hara tse ling.

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