Alkaline phosphatase: ke eng le hore na hobaneng e phahame kapa e le tlase

Litaba

• E etselitsoe eng
• 1. Phosphatase e phahameng ea alkaline
• 2. Phosphatase e nang le alkaline e tlaase
• U tla etsa tlhahlobo neng
• Tlhahlobo e etsoa joang
• Litekanyetso tsa litšupiso

Alkaline phosphatase ke enzyme e teng liseleng tse fapaneng tsa 'mele, e leng ngata haholo liseleng tsa methapo ea bile, e leng metjha e isang bile ho tsoa kahare ho sebete ho ea maleng, e etsang hore mafura a silehe, le masapong, a hlahisoang ke lisele tse amehang ho aheng le ho a boloka.

Teko ea alkaline phosphatase hangata e sebelisetsoa ho fuputsa maloetse sebeteng kapa masapong, ha matšoao le matšoao a le teng joalo ka bohloko mpeng, moroto o lefifi, lerootho kapa bofokoli ba masapo le bohloko. E ka etsoa hape joalo ka tlhatlhobo e tloaelehileng, hammoho le litlhahlobo tse ling, ho lekola bophelo ba sebete.

Le ha e le chelete e tlase, alkaline phosphatase le eona e teng ka har'a lesea, liphio le mala mme ka hona e ka phahamisoa nakong ea bokhachane kapa maemong a ho hloleha ha renal.

E etselitsoe eng

Teko ea alkaline phosphatase e sebelisetsoa ho fuputsa mathata a sebete kapa masapo mme sephetho sa ona se ka supa:

1. Phosphatase e phahameng ea alkaline

Alkaline phosphatase e ka phahama ha ho na le mathata sebeteng joalo ka:

• Thibelo ea phallo ea bile, e bakoang ke li-gallstones kapa mofetše, tse thibelang metjha e lebisang bile maling;

• Hepatitis, e leng ho ruruha sebeteng ho ka bakoang ke baktheria, livaerase kapa lihlahisoa tse chefo;

• Cirrhosis, e leng lefu le lebisang tšenyehong sebeteng;

• Ts'ebeliso ea lijo tse mafura;

• Ho se sebetse ha renal.

Ntle le moo, enzyme ena e ka ba holimo haholo maemong ao ho nang le keketseho ea ts'ebetso ea masapo, joalo ka mefuta e meng ea mofetše oa masapo kapa batho ba nang le lefu la Paget, e leng lefu le khetholloang ke kholo e sa tloaelehang ea lesapo le itseng. likarolo. Ithute haholoanyane ka lefu la Paget.

Liphetoho tse bonolo li ka boela tsa etsahala nakong ea pholiso ea ho robeha, bokhachane, AIDS, tšoaetso ea mala, hyperthyroidism, Hodgkin's lymphoma, kapa le kamora ho ja mafura a mangata.

2. Phosphatase e nang le alkaline e tlaase

Maemo a alkaline phosphatase ha a fokotsehe hangata, leha ho le joalo enzyme ena e ka fokotseha maemong a latelang:

• Hypophosphatasia, e leng lefu la lefutso le bakang ho holofala le ho robeha ha masapo;

• Khaello ea phepo e nepahetseng;

• Khaello ea Magnesium;

• Hypothyroidism;

• Letšollo le matla;

• Phokolo ea mali e matla.

Ntle le moo, litlhare tse ling tse kang pilisi ea thibelo ea bokhachane le litlhare tsa kalafo ea "hormone" tse sebelisoang nakong ea ho khaotsa ho ilela khoeli le tsona li ka baka phokotso e nyane maemong a alkaline phosphatase.

U tla etsa tlhahlobo neng

Ho hlahlojoa ha alkaline phosphatase ho lokela ho etsoa ha matšoao a matšoao a sebete a joalo ka mpa e atolositsoeng, bohloko lehlakoreng le letona la mpa, jaundice, moroto o lefifi, litulo tse bobebe le ho hlohlona ho akaretsang li teng.

Ntle le moo, tlhahlobo ena e bonts'oa hape bakeng sa batho ba nang le matšoao le boemo ba masapo joalo ka bohloko ba masapo ka kakaretso, ho holofala ha masapo kapa ba nang le mathata a ho robeha.

Tlhahlobo e etsoa joang

Teko e ka etsoa ka laboratoring, moo setsebi sa tlhokomelo ea bophelo bo botle se ka nkang 5 ml ea sampole ea mali ho tsoa mothapong o letsohong, o kentsoeng ka setshelong se koetsoeng, hore se hlahlojoe.

Litekanyetso tsa litšupiso

Litekanyetso tsa litšupiso bakeng sa tlhahlobo ea alkaline phosphatase lia fapana ho latela lilemo, ka lebaka la kholo:

Bana le bacha:

• <Lilemo tse 2: 85 - 235 U / L.
• Lilemo tse 2 ho isa ho tse 8: 65 - 210 U / L.
• Lilemo tse 9 ho isa ho tse 15: 60 - 300 U / L.
• Lilemo tse 16 ho isa ho tse 21: 30 - 200 U / L.

Batho ba baholo:

• 46 ho isa ho 120 U / L.

Nakong ea bokhachane, boleng ba mali ba alkaline phosphatase bo ka fetoloa hanyane, ka lebaka la kholo ea ngoana le hobane enzyme ena e teng lephakeng.

Hammoho le teko ena, e ka etsoa le tlhahlobo ea li-enzyme tse ling tse fumanehang sebeteng tse kang alanine aminotransferase, aspartate aminotransferase, gamma glutamyl transpeptidase le bilirubins, liteko tsa ho nka litšoantšo kapa esita le biopsy ea sebete. Bona hore na litlhahlobo tsena li etsoa joang.