Sengoli: Randy Alexander
Letsatsi La Creation: 4 April 2021
Ntlafatsa Letsatsi: 20 November 2024
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Litaba

Collagen vascular lefu

"Collagen vascular disease" ke lebitso la sehlopha sa mafu a amang likarolo tsa hau tse sebetsang. Collagen ke lisele tse ikopantseng tse thehiloeng ho protheine tse etsang sistimi ea ts'ehetso ho letlalo la hau. Lisele tse hokahanyang li tšoara masapo, li-ligamente le mesifa hammoho. Collagen vascular disease ka linako tse ling e boetse e bitsoa li-connective disease. Maloetse a Collagen vascular a ka ba lefa (le futsitsoeng ho batsoali ba motho) kapa autoimmune (e bakoang ke ts'ebetso ea sesole sa 'mele khahlanong le lona). Sengoliloeng sena se bua ka mefuta e ikemetseng ea maloetse a collagen vascular.

Mathata a mang a khetholloang e le collagen vascular disease a ama manonyeletso a hao, letlalo, methapo ea mali kapa litho tse ling tsa bohlokoa. Matšoao a fapana ho ea ka lefu le itseng.

Mefuta ea autoimmune collagen vascular lefu e kenyelletsa:

  • lupus
  • ramatiki ea ramatiki
  • scleroderma
  • arteritis ea nakoana

Mefuta ea lefu la lefutso la collagen le kenyelletsa:

  • Lefu la Ehlers-Danlos
  • Lefu la Marfan
  • Osteogenesis imperfecta (OI), kapa lefu la brittle bone

Lisosa tsa lefu la methapo ea collagen

Collagen vascular lefu ke lefu le ikemetseng. Sena se bolela hore sesole sa hau sa 'mele se etsa phoso ea ho hlasela' mele oa hau o phetseng hantle. Ha ho motho ea tsebang hore na ke eng e etsang hore sesole sa hau sa 'mele se etse sena. Hangata litlhaselo li baka ho ruruha. Haeba u na le lefu la methapo ea collagen, sesole sa hau sa 'mele se baka ho ruruha ho collagen ea hau le manonyellong a haufi.


Maloetse a mangata a li-collagen vascular, ho kenyelletsa lupus, scleroderma le ramatiki ea ramatiki, a atile haholo ho basali ho feta banna. Hangata sehlopha sena sa mafu se ama batho ba baholo ba lilemong tsa bo-30 le bo-40. Bana ba ka tlase ho lilemo tse 15 ba ka fumanoa ba na le lupus, empa e ama haholo batho ba baholo ho feta 15.

Matšoao a lefu la methapo ea collagen

Mofuta o mong le o mong oa lefu la methapo ea collagen le na le matšoao a lona. Leha ho le joalo, mefuta e mengata ea lefu la vascular collagen le na le matšoao a tšoanang. Batho ba nang le mathata a collagen vascular hangata ba ba le:

  • mokgathala
  • bofokoli ba mesifa
  • feberu
  • bohloko ba mmele
  • bohloko ba manonyeletso
  • ho phatloha hoa letlalo

Matšoao a lupus

Lupus ke lefu la methapo ea collagen le bakang matšoao a ikhethang ho mokuli ka mong. Matšoao a mang a ka kenyelletsa:

  • phefumoloho e kgutshoane
  • bohloko ba sefuba
  • ho tšoaroa ke hlooho
  • mahlo a omileng
  • stroke
  • Liso tsa molomo
  • ho senyeheloa ke maikutlo khafetsa

Batho ba nang le lupus ba ka ba le nako e telele ea ts'oarelo ntle le matšoao. Matšoao a ka phahama nakong ea khatello ea maikutlo kapa kamora ho pepesehela letsatsi nako e telele.


Matšoao a ramatiki ea ramatiki

Ramatiki ea ramatiki e ama batho ba baholo ba ka bang limilione tse 1,3 United States, ho latela Setsi sa Naha sa Arthritis le Musculoskeletal and Skin Diseases. Ho ruruha ha lisele tse hokahaneng lipakeng tsa manonyeletso ho baka bohloko le ho satalla. O kanna oa ba le mathata a sa foleng ka mahlo a omileng le molomo o omileng. Methapo ea hau ea mali kapa lesela la pelo ea hau le kanna la ruruha haeba o na le mofuta ona oa lefu la methapo ea collagen.

Matšoao a scleroderma

Scleroderma ke lefu le ikemetseng le ka amang hau:

  • letlalo
  • pelo
  • matšoafo
  • tshilo ya dijo
  • litho tse ling tsa mmele

Matšoao a kenyelletsa ho tenya le ho thatafala ha letlalo, lihlahala le liso tse bulehileng. Letlalo la hau le ka ikutloa le le thata, joalokaha eka le a otloloha, kapa la ikutloa le le bosesane libakeng. Systemic scleroderma e ka baka:

  • ho kgohlela
  • ho fehla
  • mathata a ho hema
  • letšollo
  • reflux ea acid
  • bohloko ba manonyeletso
  • ho hloka kutlo maotong a hao

Matšoao a arteritis ea nakoana

Temporal arteritis, kapa giant cell arteritis, ke mofuta o mong oa collagen vascular disease. Temporal arteritis ke ho ruruha ha methapo e meholo, hangata e hloohong. Matšoao a atile haholo bathong ba baholo ho feta lilemo tse 70 'me a kenyeletsa:


  • kutloisiso ea letlalo la hlooho
  • bohloko ba mohlahare
  • ho tšoaroa ke hlooho
  • ho lahleheloa ke pono

Kalafo ea collagen vascular disease

Kalafo ea collagen vascular disease e fapana ho latela boemo ba hau ka bomong. Leha ho le joalo, meriana ea corticosteroid le immunosuppressant hangata e phekola maloetse a mangata a sebetsang.

Corticosteroids

Corticosteroids e fokotsa ho ruruha 'meleng oohle oa hau. Sehlopha sena sa lithethefatsi se boetse se thusa ho tsitsisa sesole sa hau sa 'mele. Corticosteroids e ka ba le litla-morao tse kholo ho batho ba bang, ho kenyelletsa boima le ho fetoha ha maikutlo. Batho ba bang ba ka ba le keketseho ea tsoekere maling ha ba ntse ba noa meriana ea corticosteroid.

Li-immunosuppressants

Meriana ea Immunosuppressant e sebetsa ka ho fokotsa boits'ireletso ba hau ba mmele. Haeba karabelo ea hau ea 'mele ea ho itšireletsa mafung e le tlase,' mele oa hau o ke ke oa itlhasela joalo ka pele. Leha ho le joalo, ho ba le boits'ireletso bo tlase ho ka eketsa menyetla ea ho kula. Itšireletse ho likokoana-hloko tse bonolo ka ho lula hole le batho ba nang le sefuba kapa ntaramane.

Phekolo ea 'mele

Phekolo ea 'mele kapa boikoetliso bo bonolo le bona bo ka alafa collagen vascular disease. Boikoetliso bo bongata bo u thusa ho boloka motsamao oa hau mme bo ka fokotsa bohloko ba manonyeletso le mesifa.

Pono ea nako e telele

Ponahalo ea lefu la methapo ea collagen e fapana ho ea ka batho, 'me ho latela lefu la bona. Leha ho le joalo, li na le ntho e le 'ngoe e tšoanang: Maloetse' ohle a itšireletsang mafung ke maemo a sa foleng. Ha li na pheko, 'me u tlameha ho li laola bophelo bohle ba hau.

Lingaka tsa hau li tla sebetsa le uena ho theha moralo oa kalafo o tla u thusa ho sebetsana le matšoao a hau.

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