Sengoli: William Ramirez
Letsatsi La Creation: 20 September 2021
Ntlafatsa Letsatsi: 9 December 2024
Anonim
Vitamin B7 (Biotin)
Video: Vitamin B7 (Biotin)

Litaba

Biotin ke vithamine. Lijo tse kang mahe, lebese kapa libanana li na le biotin e nyane.

Biotin e sebelisetsoa khaello ea biotin. E boetse e sebelisoa hangata bakeng sa tahlehelo ea moriri, manala a robehileng, le maemo a mang, empa ha ho na bopaki bo botle ba mahlale bo tšehetsang ts'ebeliso ena.

Meriana ea Tlhahisoleseling e Akaretsang e sebetsa hantle ho ipapisitsoe le bopaki ba mahlale ho latela sekala se latelang: E ​​ea sebetsa, e ka sebetsa hantle, mohlomong ea sebetsa, mohlomong e sa sebetse, mohlomong e sa sebetse, e sa sebetse ebile e sa lekana Bopaki bo lokelang ho lekanyetsoa.

Likarolo tsa katleho ea BIOTIN ke tse latelang:

E ka sebetsa hantle bakeng sa ...

  • Khaello ea biotin. Ho nka biotin ho ka thusa ho phekola maemo a tlase a mali a biotin. E ka thibela le maemo a mali a biotin ho theoha haholo. Tekanyo e tlase ea mali ea biotin e ka baka ho otloloha ha moriri le ho phatloha ho potoloha mahlo, nko le molomo. Matšoao a mang a kenyelletsa khatello ea maikutlo, ho hloka thahasello, ho bona lipono le ho hlohlona matsohong le maotong. Maemo a tlase a biotin a ka hlaha ho batho ba imeng, ba fepetsoeng ka nako e telele ka li-tube, ba sa fepehang hantle, ba nang le boima ba 'mele bo potlakileng, kapa ba nang le boemo bo itseng ba futsitseng. Ho tsuba sakerete le hona ho ka baka maemo a tlase a mali a biotin.

Mohlomong ha e na thuso bakeng sa ...

  • Multiple sclerosis (MS). Tekanyo e phahameng ea biotin ha e fokolise bokooa ho batho ba nang le MS. Hape ha ho bonahale ho ama kotsi ea ho khutlela morao.
  • Letlalo le bohale, le letlalo la letlalo le sefahleho (seborrheic dermatitis). Ho nka biotin ha ho bonahale ho thusa ho ntlafatsa lebelo la masea.

Bopaki bo sa lekaneng ba ho lekanya katleho ea ...

  • Boemo bo futsitsoeng bo amang boko le likarolo tse ling tsa tsamaiso ea methapo (biotin-thiamine-response basal ganglia disease). Batho ba nang le boemo bona ba ba le linako tse fetotsoeng tsa boemo ba kelello le mesifa. Phuputso ea pejana e bonts'a hore ho nka biotin le thiamine ha ho fokotse matšoao ho feta ho nka thiamine feela. Empa motswako o ka khutsufatsa hore na mananeo ana a nka nako e kae.
  • Manala a robehileng. Patlisiso ea pele e fana ka maikutlo a hore ho nka biotin ka molomo ho fihlela selemo ho ka eketsa botenya ba manala le menoana ea menoana ho batho ba nang le lipekere tse robehileng.
  • Lefu la tsoekere. Lipatlisiso tse fokolang li bontša hore ho nka biotin ha ho ntlafatse tsoekere ea mali ho batho ba nang le lefu la tsoekere.
  • Maqhubu a mesifa. Batho ba fumanang dialysis ba na le mesifa ea mesifa. Patlisiso ea pejana e bonts'a hore ho nka biotin ka molomo ho ka fokotsa mesifa ea mesifa ho batho bana.
  • Lefu la Lou Gehrig (amyotrophic lateral sclerosis kapa ALS).
  • Ho tepella maikutlo.
  • Bohloko ba methapo ho batho ba nang le lefu la tsoekere (lefu la tsoekere la lefu la tsoekere).
  • Ho lahleheloa ke moriri ka bongata (alopecia areata).
  • Maemo a mang.
Bopaki bo bongata boa hlokahala ho lekola biotin bakeng sa ts'ebeliso ena.

Biotin ke karolo ea bohlokoa ea li-enzyme 'meleng tse senyang lintho tse ling tse kang mafura, lik'habohaedreite le tse ling.

Ha ho na tlhahlobo e ntle ea laboratori bakeng sa ho fumana maemo a tlase a biotin, ka hona boemo bona hangata bo khetholloa ke matšoao a ona, a kenyelletsang ho fokotsa moriri (khafetsa ka ho lahleheloa ke 'mala oa moriri) le lekhopho le khubelu la letlalo ho potoloha mahlo, nko le molomo . Matšoao a mang a kenyelletsa khatello ea maikutlo, mokhathala, lipono le ho tsikinyetsa matsoho le maoto. Ho na le bopaki bo bong ba hore lefu la tsoekere le ka baka maemo a tlase a biotin.

Ha e nkoa ka molomo: Biotin ke TŠOANANG POLOKO bakeng sa batho ba bangata ha li nkuoa ka molomo ka nepo. E mamelloa hantle ha e sebelisoa ka litekanyo tse khothalletsoang.

Ha e sebelisoa letlalong: Biotin ke TŠOANANG POLOKO bakeng sa batho ba bangata ha e sebelisoa letlalong e le lihlahisoa tsa litlolo tse nang le biotin e ka bang 0.6%.

Ha e fanoa e le thunya: Biotin ke MOTS'ELISI TS'IU ha e fanoa e le thunya ka har'a mesifa.

Litlhokomelo le litemoso tse khethehileng:

Bokhachane le ho anyesa: Biotin ke TŠOANANG POLOKO ha e sebelisoa ka bongata bo khothalletsoang nakong ea bokhachane le ho anyesa.

Bana: Biotin ke TŠOANANG POLOKO ha e nkoa ka molomo le ka nepo.

Boemo bo futsitsoeng moo 'mele o ke keng oa sebetsana le biotin (khaello ea biotinidase): Batho ba nang le boemo bona ba ka hloka biotin e eketsehileng.

Dialysis ea liphio: Batho ba fumanang dialysis ea liphio ba ka hloka biotin e eketsehileng. Botsa mofani oa hao oa tlhokomelo ea bophelo.

Ho tsubaBatho ba tsubang ba ka ba le maemo a tlase a biotin mme ba ka hloka tlatsetso ea biotin.

Liteko tsa laboratori: Ho nka litlatsetso tsa biotin ho ka kena-kenana le sephetho sa liteko tse ngata tse fapaneng tsa labor ea mali. Biotin e ka baka sephetho se phahameng sa bohata kapa sa bohata. Sena se ka lebisa litlhahlobong tse fosahetseng kapa tse fosahetseng. Bolella ngaka ea hau hore na u noa li-biotin, haholo-holo haeba u etsoa liteko tsa laborateng kamoo u ka hlokang ho emisa ho nka biotin pele ho tlhahlobo ea mali. Boholo ba li-multivitamine li na le tekanyetso e tlase ea biotin, e leng monyetla oa ho sitisa liteko tsa mali. Empa bua le ngaka ea hau ho netefatsa.

Ha ho tsejoe hore na sehlahisoa sena se sebelisana le meriana efe kapa efe.

Pele o nka sehlahisoa sena, bua le setsebi sa bophelo bo botle haeba u noa meriana.
Alpha-lipoic acid e
Alpha-lipoic acid le biotin tse nkoang hammoho li ka fokotsa ho monya 'mele ha e' ngoe.
Vithamine B5 (pantothenic acid)
Biotin le vithamine B5 tse nkoang hammoho li ka fokotsa ho monya 'mele ha e' ngoe.
Makhooa a mahe
Bosoeu bo bosoeu ba lehe bo ka tlama biotin ka maleng 'me ea e boloka hore e se ke ea kenella. Ho ja makhooa a mahe a mabeli kapa a mangata a sa phehoang letsatsi le letsatsi ka likhoeli tse 'maloa ho bakile khaello ea biotin e tebileng ho lekana ho hlahisa matšoao.
Litekanyo tse latelang li ithutiloe lipatlisisong tsa mahlale:

BAHOLO

KA MOLOMO:
  • Kakaretso: Ha ho na tjhelete e khothalletsoang ea lijo (RDA) e thehetsoeng biotin. Lijo tse lekaneng (AI) bakeng sa biotin ke 30 mcg bakeng sa batho ba baholo ho feta lilemo tse 18 le bakhachane, le 35 mcg bakeng sa basali ba anyesang.
  • Khaello ea biotinHo fihlela 10 mg letsatsi le letsatsi ho sebelisitsoe.
BANA

KA MOLOMO:
  • Kakaretso: Ha ho na tjhelete e khothalletsoang ea lijo (RDA) e thehiloeng bakeng sa biotin. Lijo tse lekaneng (AI) bakeng sa biotin ke 7 mcg bakeng sa masea likhoeli tse 0-12, 8 mcg bakeng sa bana ba lilemo tse 1-3, mcg tse 12 bakeng sa bana ba lilemo li 4-8, 20 mcg bakeng sa bana ba lilemo tse 9-13 le 25 mcg bakeng sa bacha. Lilemo tse 14-18.
  • Khaello ea biotin: Ho fihlela 10 mg letsatsi le leng le le leng e sebelisitsoe ho masea.
Biotina, Biotine, Biotine-D, Coenzyme R, D-Biotin, Vitamin B7, Vitamin H, Vitamine B7, Vitamine H, W Factor, Cis-hexahydro-2-oxo-1H-thieno [3,4-d] -imidazole -4-valeric acid.

Ho ithuta haholoanyane ka hore na sengoloa sena se ngotsoe joang, ka kopo bona Meriana ea Tlhahisoleseling e Akaretsang mokhoa.


  1. Cree BAC, Moqapi G, Wolinsky JS, et al. Tšireletseho le katleho ea MD1003 (biotin e phahameng) ho bakuli ba nang le multiple sclerosis e tsoelang pele (SPI2): teko ea 3, e laoloang ka bobeli, e foufetseng, e laoloang ke placebo. Lancet Neurol. 2020.
  2. Li D, Ferguson A, Cervinski MA, Lynch KL, Kyle PB. Tokomane ea Tataiso ea AACC mabapi le Litšitiso tsa Biotin Litekong tsa Laboraro. J Appl Lab Med. 2020; 5: 575-587. Sheba tse sa hlakang.
  3. Kodani M, Poe A, Drobeniuc J, Mixson-Hayden T. Qeto ea tšitiso ea biotin e ka bang teng mabapi le ho nepahala ha sephetho sa liteko tsa serologic bakeng sa matšoao a fapaneng a tšoaetso ea lefu la sebete. J Med Virol. Sheba tse sa hlakang.
  4. Branger P, Parienti JJ, Derache N, Kassis N, Assouad R, Maillart E, Defer G. Ho khutlela morao nakong ea kalafo ea High-Dose Biotin ho Progressive Multiple Sclerosis: Case-Crossover and Propensity Score-Adjusted Cohort Prohose. Phekolo ea meriana. Sheba tse sa hlakang.
  5. Tourbah A, Lebrun-Frenay C, Edan G, le al. MD1003 (High-Dose Biotin) bakeng sa Phekolo ea Progressive Multiple Sclerosis: Phuputso e laoloang ka nako e telele, e foufetseng, e laoloang ke sebaka. Mult Scler. 2016; 22: 1719-1731. Sheba tse sa hlakang.
  6. Juntas-Morales R, Pageot N, Bendarraz A, le al. Tekanyo e phahameng ea meriana ea biotin (MD1003) ho amyotrophic lateral sclerosis: Phuputso ea mofofisi. Meriana ea EClinical. 2020; 19: 100254. Sheba tse sa hlakang.
  7. Demas A, Cochin JP, Hardy C, Vaschalde Y, Bourre B, Labauge P. Tardive Reactivation of Progressive Multiple Sclerosis Nakong ea Phekolo le Biotin. Phekolo ea Neurol Ther. 2019; 9: 181-185. Sheba tse sa hlakang.
  8. Couloume L, Barbin L, Leray E, le al. Tekanyo e phahameng ea biotin ho multiple sclerosis e tsoelang pele: Phuputso e lebelletsoeng ea bakuli ba 178 litloaelong tse tloahelehileng tsa bongaka. Mult Scler. 2019: 1352458519894713. Sheba tse sa hlakang.
  9. Elecsys Anti-SARS-CoV-2 - Cobas. Roche Diagnostics GmbH. E fumaneha ho: https://www.fda.gov/media/137605/download.
  10. CM ea Trambas, Sikaris KA, Lu ZX. Tlhokomeliso mabapi le kalafo e phahameng ea biotin: tlhahlobo e fosahetseng ea hyperthyroidism ho bakuli ba euthyroid. Med J Aust. 2016; 205: 192. Sheba tse sa hlakang.
  11. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D le ba bang. Litekanyetso tse phahameng tsa biotin ho li-multiple sclerosis tse tsoelang pele tse tsoelang pele: phuputso ea mofofisi. 2015; 4: 159-69 (Khatisitsoeng) doi: 10.1016 / j.msard.2015.01.005.
  12. Tabarki B, Alfadhel M, AlShahwan S, Hundallah K, AlShafi S, AlHashem A. Phekolo ea lefu la basal ganglia le arabelang biotin: thuto e bulehileng ea papiso lipakeng tsa motsoako oa biotin hammoho le thiamine le thiamine feela. Eur J Paediatr Neurol. 2015; 19: 547-52. doi: 10.1016 / j.ejpn.2015.05.008. Sheba tse sa hlakang.
  13. FDA e Lemosa hore Biotin E kanna ea kena-kenana le Liteko tsa Lab: Puisano ea Ts'ireletso ea FDA. https://www.fda.gov/MedicalDevices/Safety/AlertsandNotices/ucm586505.htm. E ntlafalitsoe ka la 28 Pulungoana, 2017. E fihlile ka la 28 Pulungoana.
  14. Biscolla RPM, Chiamolera MI, Kanashiro I, Maciel RMB, Vieira JGH. A single 10? Mg Oral Dose ea Biotin Interferes e nang le Liteko tsa Ts'ebetso ea Thyroid. Thyroid ea 2017; 27: 1099-1100. Sheba tse sa hlakang.
  15. Piketty ML, Prie D, Sedel F, le al. Phekolo ea tefo e phahameng ea biotin e lebisang profilng ea bohata ea biochemical endocrine: netefatso ea mokhoa o bonolo oa ho hlola tšitiso ea biotin. Kliniki ea Chem Lab Med 2017; 55: 817-25. Sheba tse sa hlakang.
  16. CM ea Trambas, Sikaris KA, Lu ZX. Ho eketsehileng ka Biotin Treatment Mimicking Graves ’Disease. N Engl J Med 2016; 375: 1698. Sheba tse sa hlakang.
  17. Elston MS, Sehgal S, Du Toit S, Yarndley T, Conaglen JV. Lefu la Factitious Graves ka lebaka la tšitiso ea biotin immunoassay-nyeoe le tlhahlobo ea lingoliloeng. J Clin Endocrinol Metab 2016; 101: 3251-5. Sheba tse sa hlakang.
  18. Kummer S, Hermsen D, Distelmaier F. Biotin kalafo e etsisang lefu la mabitla. N Engl J Med 2016; 375: 704-6. Sheba tse sa hlakang.
  19. Barbesino G. Misdiagnosis ea lefu la Graves e nang le hyperthyroidism e matla haholo ho mokuli ea sebelisang biotin megadoses. Thyroid 2016; 26: 860-3. Sheba tse sa hlakang.
  20. Sulaiman RA. Kalafo ea Biotin e bakang liphetho tse fosahetseng tsa ho itšireletsa mafung: Tlhokomeliso ho lingaka. Lithethefatsi Discov Ther 2016; 10: 338-9. Sheba tse sa hlakang.
  21. Bülow Pedersen I, Laurberg P. Biochemical Hyperthyroidism ho lesea le sa tsoa tsoaloa le bakiloeng ke Assay Interaction ho tsoa Biotin Intake. Eur Thyroid J 2016; 5: 212-15. Sheba tse sa hlakang.
  22. Minkovsky A, Lee MN, Dowlatshahi M, le al. Kalafo e phahameng ea biotin bakeng sa sclerosis e tsoelang pele ea multiple sclerosis e ka kena-kenana le liteko tsa qoqotho. AACE Clinic Rep 2016; 2: e370-e373. Sheba tse sa hlakang.
  23. Oguma S, Ando I, Hirose T, et al. Biotin e ntlafatsa mesifa ea mesifa ea bakuli ba hemodialysis: teko e lebelletsoeng. Tohoku J Exp Med 2012; 227: 217-23. Sheba tse sa hlakang.
  24. Waghray A, Milas M, Nyalakonda K, Siperstein AE. Hormone e tlaase ea parathyroid ea bobeli ho kena-kenana le biotin: letoto la linyeoe. Mokhoa oa Endocr 2013; 19: 451-5. Sheba tse sa hlakang.
  25. Kwok JS, Chan IH, Chan MH. Ho kena-kenana ha Biotin le TSH le ho lekanya litekanyo tsa lihomone tsa qoqotho. Bolwetse. 2012; 44: 278-80. Sheba tse sa hlakang.
  26. Vadlapudi AD, Vadlapatla RK, Mitra AK. Transporter ea multivitamin e itšetlehileng ka sodium (SMVT): sepheo se ka hlahisoang ke phano ea lithethefatsi. Lits'oants'o tsa lithethefatsi tsa Curr 2012; 13: 994-1003. Sheba tse sa hlakang.
  27. Pacheco-Alvarez D, Solórzano-Vargas RS, Del Río AL. Biotin ho Metabolism le Kamano ea eona le Mafu a Batho. Arch Med Res 2002; 33: 439-47. Sheba tse sa hlakang.
  28. Sydenstricker, V. P., Singal, S. A., Briggs, A. P., Devaughn, N. M., le Isbell, H. Ho shebella "kotsi e tšoeu ea lehe" ho motho le pheko ea eona ka mohopolo oa biotin. J Am Med Assn 1942;: 199-200.
  29. Ozand, PT, Gascon, GG, Al Essa, M., Joshi, S., Al Jishi, E., Bakheet, S., Al Watban, J., Al Kawi, MZ, le Dabbagh, O. Biotin-reaction basal lefu la ganglia: mokhatlo o hlophisitsoeng. Bokooa 1998; 121 (Pt 7): 1267-1279. Sheba tse sa hlakang.
  30. Wallace, J. C., Jitrapakdee, S., le Chapman-Smith, A. Pyruvate carboxylase. Int J Likokoana-hloko. 1998; 30: 1-5. Sheba tse sa hlakang.
  31. Zempleni, J., Green, G. M., Spannagel, A. W., le Mock, D. M. Biliary excretion ea biotin le biotin metabolites e ngata haholo ho likhoto le likolobe. J Phepo. 1997; 127: 1496-1500. Sheba tse sa hlakang.
  32. Zempleni, J., McCormick, D. B., le Mock, D. M. Boitsebiso ba biotin sulfone, bisnorbiotin methyl ketone, le tetranorbiotin-l-sulfoxide ka morong oa motho. Ke. J Tleliniki. 1997; 65: 508-511. Sheba tse sa hlakang.
  33. van der Knaap, M. S., Jakobs, C., le Valk, J. Papiso ea matla a khoheli a lactic acidosis. J Lefa. Metab Dis. 1996; 19: 535-547. Sheba tse sa hlakang.
  34. Shriver, B. J., Roman-Shriver, C., le Allred, J. B. Ho felisoa le ho tlatlapa ha li-enzyme tsa biotinyl sebeteng sa likhoto tse haelloang ke biotin: bopaki ba sistimi ea polokelo ea biotin. J Phepo. 1993; 123: 1140-1149.Sheba tse sa hlakang.
  35. McMurray, D. N. Ho itšireletsa mafung ka seleng khaello ea phepo e nepahetseng. Prog.Lijo tse nang le phepo Sci 1984; 8 (3-4): 193-228. Sheba tse sa hlakang.
  36. Ammann, A. J. Kutloisiso e ncha ea lisosa tsa mathata a ho itšireletsa mafung. J Ke Acad.Dermatol. 1984; 11 (4 Pt 1): 653-660. Sheba tse sa hlakang.
  37. Petrelli, F., Moretti, P., le Paparelli, M. Kabo ea li-intracellular ea biotin-14COOH ka sebete sa rat. Mol. Bofoli. 2-15-1979; 4: 247-252. Sheba tse sa hlakang.
  38. Zlotkin, S. H., Stallings, V. A., le Pencharz, P. B. Kakaretso ea phepo ea malapa ho bana. Pediatr Clinic Leboea Am. 1985; 32: 381-400. Sheba tse sa hlakang.
  39. Bowman, B. B., Selhub, J., le Rosenberg, I. H. Ho monya mala a biotin ho rat. J Phepo. 1986; 116: 1266-1271. Sheba tse sa hlakang.
  40. Magnuson, N. S. le Perryman, L. E. Mefokolo ea metabolism ho matla a kopaneng a ho itšireletsa mafung ho motho le liphoofolo. Comp Biochemistry Physiol B 1986; 83: 701-710. Sheba tse sa hlakang.
  41. Nyhan, W. L. Liphoso tsa tlhaho ea biotin metabolism. Arch.Dermatol. 1987; 123: 1696-1698a. Sheba tse sa hlakang.
  42. Sweetman, L. le Nyhan, W. L. Mathata a ka phekolehang a biotin le lintho tse amanang le ona. Tšen. 1986; 6: 317-343. Sheba tse sa hlakang.
  43. Brenner, S. le Horwitz, C. Bakena-lipakeng ba nang le phepo e ka bang teng ho psoriasis le seborrheic dermatitis. II. Balamelli ba phepo e nepahetseng: mafura a mafura a bohlokoa; livithamini A, E le D; livithamini B1, B2, B6, niacin le biotin; selenium ea vithamine C; zinki; tšepe. Moruti oa Lefatše Lijo. 1988; 55: 165-182. Sheba tse sa hlakang.
  44. Miller, S. J. Khaello ea phepo e nepahetseng le letlalo. J Ke Acad.Dermatol. 1989; 21: 1-30. Sheba tse sa hlakang.
  45. Michalski, A. J., Berry, G.T, le Segal, S. Holocarboxylase synthetase khaello: Ts'ebetso ea lilemo tse 9 tsa mokuli kalafong e sa foleng ea biotin le tlhahlobo ea lingoliloeng. J Lefa. Metab Dis. 1989; 12: 312-316. Sheba tse sa hlakang.
  46. Colombo, V. E., Gerber, F., Bronhofer, M., le Floersheim, G. L. Phekolo ea manala a brittle le onychoschizia ka biotin: ho sekaseka microscopy ea elektronike. J Ke Acad.Dermatol. 1990; 23 (6 Pt 1): 1127-1132. Sheba tse sa hlakang.
  47. Daniells, S. le Hardy, G. Ho lahleheloa ke moriri ka phepo ea nako e telele kapa ea malapa: na ke khaello ea li-micronutrient e lokelang ho beoa molato? Curr.Opin.Clin.Nutr.Metab Tlhokomelo 2010; 13: 690-697. Sheba tse sa hlakang.
  48. Wolf, B. Litaba tsa bongaka le lipotso tse botsoang khafetsa mabapi le khaello ea biotinidase. Mol. Genet.Metab 2010; 100: 6-13. Sheba tse sa hlakang.
  49. Zempleni, J., Hassan, Y. I., le Wijeratne, S. S. Biotin le khaello ea biotinidase. Setsebi Rev. Rev Endocrinol.Metab 11-1-2008; 3: 715-724. Sheba tse sa hlakang.
  50. Tsao, C.Y. Mekhoa ea hajoale ea ho phekola li-spasms tsa masea. Phekolo ea Neuropsychiatr. 2009; 5: 289-299. Sheba tse sa hlakang.
  51. Sedel, F., Lyon-Caen, O., le Saudubray, J. M. [Mafu a tšoaroang a lefutso a lefu la methapo]. Moruti Neurol. (Paris) 2007; 163: 884-896. Sheba tse sa hlakang.
  52. Sydenstricker, V. P., Singal, S. A., Briggs, A. P., Devaughn, N. M., le Isbell, H. TLHOKOMELISO EA MABAPI LE "EGG WHITE WHITE" HO BATHO LE Pheko ea Eona ka Biotine CONCENTRATE. Saense 2-13-1942; 95: 176-177. Sheba tse sa hlakang.
  53. Scheinfeld, N., Dahdah, M. J., le Scher, R. Li-vithamini le liminerale: karolo ea bona ho bophelo ba lipekere le mafu. J Lithethefatsi tsa Dermatol. 2007; 6: 782-787. Sheba tse sa hlakang.
  54. Spector, R. le Johanson, C. E. Lipalangwang tsa vithamine le homeostasis bokong ba mamalia: tsepamisa maikutlo ho Vithamini B le E. J Neurochem. 2007; 103: 425-438. Sheba tse sa hlakang.
  55. Mock, D. M. Letlalo liponahatso tsa khaello ea biotin. Semin.Dermatol. 1991; 10: 296-302. Sheba tse sa hlakang.
  56. Bolander, F. F. Vithamini: eseng feela bakeng sa li-enzyme. Curr.Opin.Investig. Lithethefatsi 2006; 7: 912-915. Sheba tse sa hlakang.
  57. Prasad, A. N. le Seshia, S. S. Boemo ba lefu la sethoathoa lithutong tsa bana: ho tloha bocheng ho ea ho bocha. Adv.Neurol. 2006; 97: 229-243. Sheba tse sa hlakang.
  58. Wilson, CJ, Myer, M., Darlow, BA, Stanley, T., Thomson, G., Baumgartner, ER, Kirby, DM, le Thorburn, DR Severe holocarboxylase synthetase khaello e nang le karabelo e sa phethoang ea biotin e hlahisang thohako ea pelehi ho masamane . J Phekolo ea bana. 2005; 147: 115-118. Sheba tse sa hlakang.
  59. Mock, D. M. Khaello ea biotin e ka thoko ke litoeba mme mohlomong le batho: tlhahlobo ea khaello ea biotin nakong ea bokhachane ba motho le litlamorao tsa khaello ea biotin ponts'ong ea liphatsa tsa lefutso le lits'ebetso tsa enzyme letamong la pompo le lesea. J Phepo e nepahetseng. 2005; 16: 435-437. Sheba tse sa hlakang.
  60. Fernandez-Mejia, C. Litlamorao tsa litlhare tsa biotin. J Phepo e nepahetseng. 2005; 16: 424-427. Sheba tse sa hlakang.
  61. Dakshinamurti, K. Biotin - molaoli oa polelo ea liphatsa tsa lefutso. J Phepo e nepahetseng. 2005; 16: 419-423. Sheba tse sa hlakang.
  62. Zeng, WQ, Al Yamani, E., Acierno, JS, Jr., Slaugenhaupt, S., Gillis, T., MacDonald, ME, Ozand, PT, le Gusella, JF Biotin-arabelang basal ganglia limmapa ho 2q36.3. 'me e bakoa ke liphetoho tse SLC19A3. Ke. J Hum. 2005; 77: 16-26. Sheba tse sa hlakang.
  63. Baumgartner, M. R. Mechini ea limolek'hule tsa polelo e hlahelletseng ho hlokeng 3-methylcrotonyl-CoA carboxylase. J Lefa. Metab Dis. 2005; 28: 301-309. Sheba tse sa hlakang.
  64. Pacheco-Alvarez, D., Solorzano-Vargas, RS, Gravel, RA, Cervantes-Roldan, R., Velazquez, A., le Leon-Del-Rio, A. Taolo e makatsang ea ts'ebeliso ea biotin bokong le sebeteng le litlamorao tsa e futsitse khaello ea li-carboxylase tse ngata. J Biol Chem. 12-10-2004; 279: 52312-52318. Sheba tse sa hlakang.
  65. Snodgrass, S. R. Vitamin methapo ea kutlo. Mol. Neurobiol. 1992; 6: 41-73. Sheba tse sa hlakang.
  66. Campistol, J. [Ho tsitsipana le ho tšoaroa ke sethoathoa sa lesea le sa tsoa tsoaloa. Mefuta ea phatlalatso, melaoana ea ho ithuta le kalafo]. Moruti Neurol. 10-1-2000; 31: 624-631. Sheba tse sa hlakang.
  67. Narisawa, K. [Motheo oa limolek'hule tsa liphoso tsa tlhaho tse amohelang vithamine ea metabolism]. Nippon Rinsho 1999; 57: 2301-2306. Sheba tse sa hlakang.
  68. Furukawa, Y. [Ntlafatso ea ts'oaetso ea insulin e bakoang ke tsoekere le phetoho ea metabolism ea glucose ka biotin]. Nippon Rinsho 1999; 57: 2261-2269. Sheba tse sa hlakang.
  69. Zempleni, J. le Mock, D. M. Tlhahlobo e tsoetseng pele ea methapo ea methapo ea methapo ea mali meleng ea mmele e lumella litekanyo tse nepahetseng haholoanyane tsa biotin bioavailability le metabolism bathong. J Phepo. 1999; 129 (2S Tlatsetso): 494S-497S. Sheba tse sa hlakang.
  70. Hymes, J. le Wolf, B. Batho biotinidase ha se feela bakeng sa ho nchafatsa biotin. J Phepo. 1999; 129 (2S Tlatsetso): 485S-489S. Sheba tse sa hlakang.
  71. Zempleni J, Mock DM. Biotin biochemistry le litlhokahalo tsa batho. J Nutriti ea Likokoana-hloko. 1999 Mar; 10: 128-38. Sheba tse sa hlakang.
  72. Eakin RE, Snell EE, le Williams RJ. Ho tsepamisa mohopolo le teko ea li-avidin, tse hlahisang likotsi tse tšoeu ka lehe le tala. J Biol Chem. 1941;: 535-43.
  73. Spencer RP le Brody KR. Tsamaiso ea biotin ka mala a manyane a likhoto, hamster le mefuta e meng. Ke J Physiol. 1964 Hlakubele; 206: 653-7. Sheba tse sa hlakang.
  74. Zempleni J, Wijeratne SS, Hassan YI. Biotin. Li-biofactors. 2009 Jan-Feb; 35: 36-46. Sheba tse sa hlakang.
  75. Green NM. Avidin. 1. Ts'ebeliso ea (14-C) biotin bakeng sa lithuto tsa kinetic le bakeng sa tlhahlobo. Likokoana-hloko. J. 1963; 89: 585-591. Sheba tse sa hlakang.
  76. Rodriguez-Melendez R, Griffin JB, Zempleni J. Biotin tlatsetso e eketsa polelo ea cytochrome P450 1B1 liphatsa tsa lefutso liseleng tsa Jurkat, e leng ho eketsang ketsahalo ea likheo tsa DNA tse le 'ngoe. J Phepo. 2004 Sep; 134: 2222-8. Sheba tse sa hlakang.
  77. Grundy WE, Re Lokollotsoe M, Johnson HC, et al. Phello ea phthalylsulfathiazole (sulfathalidine) phelisong ea livithamini tsa B ke batho ba baholo ba tloaelehileng. Arch Biochem. 1947 Mantaha; 15: 187-94. Sheba tse sa hlakang.
  78. Roth K.S. Biotin meriana ea bongaka - tlhahlobo. Am J Lithethefatsi tsa Kliniki. 1981 Sep; 34: 1967-74. Sheba tse sa hlakang.
  79. Fiume MZ. Sehlopha sa Setsebi sa Tlhahlobo ea Motsoako oa Litlolo. Tlaleho ea hoqetela ka tlhahlobo ea polokeho ea biotin. Int J Toxicol. 2001; 20 Tlatsetso ea 4: 1-12. Sheba tse sa hlakang.
  80. Geohas J, Daly A, Juturu V, le al. Motsoako oa Chromium picolinate le biotin o fokotsa atherogenic index ea plasma ho bakuli ba nang le mofuta oa 2 oa lefu la tsoekere: teko ea bongaka e laoloang ka "placebo", e foufalitsoeng habeli. Ke J Med Sci. 2007 Mar; 333: 145-53. Sheba tse sa hlakang.
  81. Ebek, Inc. e fana ka khopotso ea boithatelo naheng ka bophara ea Liviro3, sehlahisoa se rekisoang e le tlatsetso ea lijo. Phatlalatso ea Ebek Press, la 19 Pherekhong 2007. E fumaneha ho: http://www.fda.gov/oc/po/firmrecalls/ebek01_07.html.
  82. Singer GM, Geohas J. Phello ea chromium picolinate le biotin supplementation taolong ea glycemic ho bakuli ba sa laoloang hantle ba nang le mofuta oa 2 oa lefu la tsoekere: teko e laoloang ke placebo, e foufalitsoeng habeli, e sa sebetseng. Lefu la tsoekere Technol Ther 2006; 8: 636-43. Sheba tse sa hlakang.
  83. Rathman SC, Eisenschenk S, McMahon RJ. Bongata le ts'ebetso ea li-enzyme tse itšetlehileng ka biotin li fokotsoa ka likhoto tse laoloang khafetsa carbamazepine. J Meriana 2002; 132: 3405-10. Sheba tse sa hlakang.
  84. Qhekella DM, Dyken ME. Biotin catabolism e potlakisoa ho batho ba baholo ba fumanang kalafo ea nako e telele ka li-anticonvulsants. Neurology 1997; 49: 1444-7. Sheba tse sa hlakang.
  85. Albarracin C, Fuqua B, Evans JL, ID ea Goldfine. Motsoako oa Chromium picolinate le biotin o ntlafatsa metabolism ea glucose ha e phekoloa, e le boima bo feteletseng bo feteletseng ho bakuli ba nang le lefu la tsoekere la mofuta oa 2. Lefu la tsoekere Metab Res 2008; 24: 41-51. Sheba tse sa hlakang.
  86. Geohas J, Finch M, Juturu V, le al. Ntlafatso ea ho itima lijo ka tsoekere ea mali le motswako oa Chromium Picolinate le Biotin ho Mofuta oa 2 oa lefu la tsoekere Mellitus. Kopano ea selemo le selemo ea bo-64 ea American Diabetes Association, ka Phuptjane 2004, Orlando, Florida, 191-OR.
  87. Qhekella DM, Dyken ME. Ho haella ha Biotin ho bakoa ke kalafo ea nako e telele e nang le li-anticonvulsants (abstract). Gastroenterology 1995; 108: A740.
  88. Krause KH, Berlit P, Bonjour JP. Boemo ba vithamine ho bakuli ba kalafo e sa foleng ea anticonvulsant. Int J Vitam Nut Res Res 1982; 52: 375-85. Sheba tse sa hlakang.
  89. Krause KH, Kochen W, Berlit P, Bonjour JP. Ho tlosoa ha li-acid tsa manyolo tse amanang le khaello ea biotin kalafo e sa foleng ea anticonvulsant. Int J Vitam Nutr Res ea 1984; 54: 217-22. Sheba tse sa hlakang.
  90. Sealey WM, Teague AM, Stratton SL, Mock DM. Ho tsuba ho potlakisa biotin catabolism ho basali. Am J Lithethefatsi tsa Kliniki 2004; 80: 932-5. Sheba tse sa hlakang.
  91. Qhekella NI, Malik MI, Stumbo PJ, et al. Keketseho ea ho ntša metsi ka metsing ea 3-hydroxyisovaleric acid le ho fokotsa ho ntša metsi ka moroto oa biotin ke matšoao a qalang a boemo bo fokotsehileng ba khaello ea liteko tsa biotin. Am J Lithethefatsi tsa Kliniki 1997; 65: 951-8. Sheba tse sa hlakang.
  92. Baez-Saldana A, Zendejas-Ruiz I, Revilla-Monsalve C, le al. Litlamorao tsa biotin ho pyruvate carboxylase, acetyl-CoA carboxylase, propionyl-CoA carboxylase, le matšoao a tsoekere le lipid homeostasis ea mofuta oa 2 oa bakuli ba lefu la tsoekere le lithuto tsa nondiabetic. Am J Lithethefatsi tsa Kliniki 2004; 79: 238-43. Sheba tse sa hlakang.
  93. Zempleni J, Mock DM. Bioavailability ea biotin e fanoang ka molomo ho batho ka litekanyetso tsa pharmacologic. Am J Lithethefatsi tsa Kliniki 1999; 69: 504-8. Sheba tse sa hlakang.
  94. Ho boletse HM. Biotin: vithamine e lebetsoeng. Am J Lithethefatsi tsa Kliniki. 2002; 75: 179-80. Sheba tse sa hlakang.
  95. Keipert JA. Tšebeliso ea molomo ea biotin ho seborrhoeic dermatitis ea boseeng: teko e laoloang. Med J Aust 1976; 1: 584-5 (Khatisitsoeng) Sheba tse sa hlakang.
  96. Koutsikos D, Agroyannis B, Tzanatos-Exarchou H.Biotin bakeng sa lefu la tsoekere la pheripheral neuropathy. Biomed Pharmacother 1990; 44: 511-4. Sheba tse sa hlakang.
  97. Coggeshall JC, Heggers JP, Robson MC, le al. Boemo ba Biotin le tsoekere ea plasma ho batho ba nang le lefu la tsoekere. Ann N Y Acad Sci 1985; 447: 389-92.
  98. Zempleni J, Helm RM, Mock DM. Ho vivo biotin supplementation ka tekanyetso ea pharmacologic ho fokotsa sekhahla sa keketseho ea lisele tsa mali tsa mononuclear tsa mali le tokollo ea cytokine. J Phekolo ea 2001; 131: 1479-84. Sheba tse sa hlakang.
  99. Ho soma DM, Quirk JG, Ho soma NI. Ho haella ha biotin kahare nakong ea bokhachane bo tloaelehileng. Am J Lithethefatsi tsa Meriana 2002; 75: 295-9. Sheba tse sa hlakang.
  100. Camacho FM, Garcia-Hernandez MJ. Zinc aspartate, biotin, le clobetasol propionate kalafong ea alopecia areata bongoaneng. Pediatr Dermatol 1999; 16: 336-8. Sheba tse sa hlakang.
  101. Boto ea Lijo le Phepo, Setsi sa Bongaka. Litekanyetso tsa lijo tse fumanehang bakeng sa Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin le Choline. Washington, DC: National Academy Press, 2000. E fumaneha ho: http://books.nap.edu/books/0309065542/html/.
  102. Leralla MJ. Limela tsa ka maleng le tlhahiso ea vithamine e sa feleng. Kankere ea Eur J ea Pele ho 1997; 6: S43-5. Sheba tse sa hlakang.
  103. Tonakholo ea Debourdeau, Djezzar S, Estival JL, et al. Phallo e kotsi ea lefu la 'mele e amanang le livithamini B5 le H. Ann Pharmacother 2001; 35: 424-6. Sheba tse sa hlakang.
  104. Shils ME, Olson JA, Shike M, Ross AC, bahlophisi. Phepo ea Kajeno Bophelong bo Botle le Mafu. La 9th. Baltimore, MD: Williams le Wilkins, 1999.
  105. Lininger SW. Khemisi ea Tlhaho. 1 ed. Rocklin, CA: Ho Hatisa Pele; 1998.
  106. Qhekella DM, Seki NI, Nelson RP, Lombard KA. Ho senyeha ha metabolism ea biotin ho bana ba nang le kalafo ea nako e telele ea anticonvulsant. J Pediatr Gastroentereol Phepo e nepahetseng 1998; 26: 245-50. Sheba tse sa hlakang.
  107. Krause KH, Bonjour JP, Berlit P, boemo ba Kochen W. Biotin ba lefu la sethoathoa. Ann N Y Acad Sci 1985; 447: 297-313. Sheba tse sa hlakang.
  108. Bonjour JP. Biotin phepo ea motho. Ann N Y Acad Sci 1985; 447: 97-104. Sheba tse sa hlakang.
  109. Ho boletse HM, Redha R, Nylander W. Biotin ho tsamaisa ka maleng a motho: thibelo ea lithethefatsi tse thibelang likokoana-hloko. Am J Lithethefatsi tsa Kliniki 1989; 49: 127-31. Sheba tse sa hlakang.
  110. LG ea Hochman, Scher RK, Meyerson MS. Manala a robehileng: karabelo ho tlatsetso ea biotin ea letsatsi le letsatsi. Cutis. 1993; 51: 303-5. Sheba tse sa hlakang.
  111. Henry JG, Sobki S, Afafat N. Ho kenella ka biotin therapy ka tekanyo ea TSH le FT4 ka enzyme immunoassay ho mohlahlobi oa Boehringer Mannheim ES 700. Ann Clin Biochem 1996; 33: 162-3. Sheba tse sa hlakang.
Qetellong ho hlahlojoa - 12/11/2020

Khetho Ea Sebaka

Ho Phahamisoa ha Lash le Letlalo la Hao
Bophelo

Ho Phahamisoa ha Lash le Letlalo la Hao

Ho phahami a ka matla ke tumello e fanang ka t 'ehet o ea ho nka libeke t e telele le ho koala maqeba a hau ntle le ho enya li ebeli oa, li ebeli oa t e kobehileng le maqeba a bohata. T amai o ena...
Ntho e ngoe le e ngoe eo o hlokang ho e tseba ka likonopo tsa masea a masea
Bophelo

Ntho e ngoe le e ngoe eo o hlokang ho e tseba ka likonopo tsa masea a masea

Re kenyellet a lihlahi oa t eo re nahanang hore li na le thu o ho babali ba rona. Haeba u reka ka lihokela t e leqepheng lena, re ka fumana khomi hene e nyane. T 'ebet o ea rona ke ena.Re kenyelle...