Teko ea mali ea Antithrombin III

Antithrombin III (AT III) ke protheine e thusang ho laola ho hoama ha mali. Teko ea mali e ka supa palo ea AT III e teng 'meleng oa hau.

Ho hlokahala sampole ea mali.

Meriana e meng e ka ama sephetho sa tlhahlobo. Mofani oa hao oa tlhokomelo ea bophelo a ka u joetsa hore u khaotse ho noa meriana e itseng kapa u theole lethal dose pele ho tlhahlobo. Se ke oa emisa ho noa moriana pele u bua le mofani oa litšebeletso.

Ha nale e kentsoe ho hula mali, batho ba bang ba utloa bohloko bo itekanetseng. Ba bang ba ikutloa feela ho hlaba kapa ho hlaba. Kamora moo, ho ka ba le ho phatloha kapa ho longoa hanyane. Haufinyane sena sea fela.

Mofani oa hau a ka odara tlhahlobo ena haeba o pheta ho pheta mali kapa haeba moriana o fokotsang mali o sa sebetse.

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Bua le mofani oa hau ka moelelo oa sephetho sa hau sa liteko.

AT III e tlase ho feta e tloaelehileng e ka bolela hore o na le kotsi e eketsehileng ea ho koala mali. Sena se ka etsahala ha ho se na AT III e lekaneng maling a hao, kapa ha ho na le AT III e lekaneng maling a hao, empa AT III ha e sebetse hantle ebile ha e sebetse hakaalo.

Liphetho tse sa tloaelehang li kanna tsa se hlahe ho fihlela u le motho e moholo.

Mehlala ea mathata a amanang le keketseho ea ho koala mali ke:

• Thrombosis e tebileng ea venous
• Phlebitis (ho ruruha ha methapo)
• Motsoako oa pulmonary (mali a kenang matšoafong)
• Thrombophlebitis (ho ruruha ha methapo ka sebopeho sa maqeba)

Ka tlase ho AT III e tloaelehileng e ka ba ka lebaka la:

• Ho kenyelletsa masapo a masapo
• E phatlalalitse coagulation ea methapo ea methapo (DIC)
• Ho haella ha AT III, ke boemo ba lefa
• Cirrhosis ea sebete
• Lefu la Nephrotic

E phahameng ho feta e tloaelehileng AT III e ka bakoa ke:

• Ts'ebeliso ea li-anabolic steroids
• Bleeding disorder (hemophilia)
• Ho kenyelletsa liphio
• Boemo bo tlase ba vithamine K

Ha ho na kotsi e kholo ea ho nkuoa mali a hau. Methapo le methapo li fapana ka boholo ho tloha ho motho e mong ho ea ho o mong, le ho tloha lehlakoreng le leng la 'mele ho ea ho le leng. Ho fumana sampole ea mali ho batho ba bang ho ka ba thata ho feta ho ba bang.

Likotsi tse ling li ka kenyelletsa:

• Ho tsoa mali a mangata
• Ho akheha kapa ho ikutloa o le hlooho e boima
• Li-punctures tse ngata ho fumana methapo
  
• Hematoma (mali a bokellanang ka tlasa letlalo)
• Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

Antithrombin; AT III; KA 3; Ts'ebetso ea antithrombin III; Bothata ba ho khaola - AT III; DVT - AT III; Bothata ba methapo ea pelo - AT III

Anderson JA, Kogg KE, Weitz JI. Hypercoagulation e re. Ka: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Melao-motheo le Tloaelo ea Motheo. La 7th. Philadelphia, PA: Elsevier; 2018: khaolo ea 140.

CC ea Chernecky, Berger BJ. Teko ea Antithrombin III (AT-III) - tlhahlobo ea lefu lena. Ka: Chernecky CC, Berger BJ, bahlophisi. Liteko tsa Laboraro le Mekhoa ea Tlhatlhobo. La 6th. St Louis, MO: Elsevier Saunders; 2013: 156-157.

Napolitano M, Schmaier AH, Kessler CM. Coagulation le fibrinolysis. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. St Louis, MO: Elsevier; 2017: khaolo ea 39.