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Thibela-mafu ea thyroid ea peroxidase - Moriana
Thibela-mafu ea thyroid ea peroxidase - Moriana

Li-microsomes li fumaneha ka har'a lisele tsa qoqotho. 'Mele o hlahisa li-antibodies ho microsomes ha ho bile le tšenyo liseleng tsa qoqotho. Teko ea antibody e thibelang likokoana-hloko ea microsomal e lekanya lithibela-mafu tsena maling.

Ho hlokahala sampole ea mali.

Ha nale e kentsoe ho hula mali, batho ba bang ba utloa bohloko bo itekanetseng. Ba bang ba ikutloa feela ho hlaba kapa ho hlaba. Kamora moo, ho ka ba le ho phatloha kapa ho longoa hanyane. Haufinyane sena sea fela.

Teko ena e etsoa ho netefatsa sesosa sa mathata a qoqotho, ho kenyeletsoa Hashimoto thyroiditis.

Tlhahlobo e boetse e sebelisetsoa ho fumana hore na ts'oaetso ea "immune" kapa "autoimmune" e senya qoqotho.

Teko e fosahetseng e bolela hore sephetho se tloaelehile.

Mekhahlelo e tloaelehileng ea boleng e ka fapana hanyane hara lilaboratori tse fapaneng. Li-lab tse ling li sebelisa litekanyo tse fapaneng kapa li ka leka mefuta e fapaneng. Bua le mofani oa tlhokomelo ea bophelo mabapi le moelelo oa sephetho sa hau sa liteko.

Teko e ntle e ka bakoa ke:

  • Granulomatous thyroiditis (e itšireletsa mafung ea tšoelesa ea qoqotho e atisang ho latela tšoaetso e phahameng ea phefumoloho)
  • Hashimoto thyroiditis (karabelo ea sesole sa 'mele khahlanong le tšoelesa ea qoqotho)

Mefuta e phahameng ea li-antibodies tsena le eona e hokahantsoe le kotsi e eketsehileng ea:


  • Ho nyopa
  • Preeclampsia (khatello e phahameng ea mali le protheine ka morong kamora beke ea bo20 ea bokhachane)
  • Ho tsoaloa pele ho nako
  • Ho hloleha ha manyolo ka in vitro

Bohlokoa: Hase kamehla sephetho se setle se bolelang hore u na le lefu la qoqotho kapa hore u hloka kalafo bakeng sa qoqotho ea hau. Sephetho se setle se ka bolela hore o na le monyetla o moholo oa ho ba le lefu la qoqotho nakong e tlang. Hangata hona ho amahanngoa le nalane ea lelapa ea lefu la qoqotho.

Li-antibodies tsa Antithyroid microsomal li ka bonoa maling a hau haeba u na le maemo a mang a autoimmune, ho kenyelletsa:

  • Ho iketsetsa mali ha hemolytic anemia
  • Ho itšireletsa mafung lefu la sebete
  • Ho itšireletsa mafung a adrenal
  • Ramatiki ea ramatiki
  • Sjögren lefu
  • Sesebelisoa sa lupus erythematosus

Ha ho na kotsi e kholo ea ho nkuoa mali a hau. Methapo le methapo li fapana ka boholo ho tloha ho motho e mong ho ea ho o mong le ho tloha lehlakoreng le leng la 'mele ho ea ho le leng. Ho fumana sampole ea mali ho batho ba bang ho ka ba thata ho feta ho ba bang.


Likotsi tse ling tse amanang le ho huloa mali li nyane empa li ka kenyelletsa:

  • Ho tsoa mali a mangata
  • Ho akheha kapa ho ikutloa o le hlooho e boima
  • Li-punctures tse ngata ho fumana methapo
  • Hematoma (mali a hahiloeng ka tlas'a letlalo)
  • Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

Thibela-mafu ea qoqotho ea qoqotho; Lithibela-mafu antimicrosomal; Sesole sa mmele sa microsomal; Lanthibi e thibelang likokoana-hloko ea Antithyroid; TPOAb; Anti-TPO lesole la mmele

  • Teko ea mali

Chang AY, Auchus RJ. Matšoenyeho a endocrine a amang ho ikatisa. Ka: Strauss JF, Barbieri RL, lingoliloeng. Endocrinology ea ho Ikatisa ea Yen & Jaffe. La 8th. Philadelphia, PA: Elsevier; 2019: khaolo ea 24.

CC ea Chernecky, Berger BJ. Thyroid peroxidase (TPO, antimicrosomal antibody, antithyroid microsomal antibody) antibody - mali. Ka: Chernecky CC, Berger BJ, bahlophisi. Liteko tsa Laboraro le Mekhoa ea Tlhatlhobo. La 6th. St Louis, MO: Elsevier Saunders; 2013: 1080-1081.


Guber HA, Farag AF. Tlhatlhobo ea ts'ebetso ea endocrine. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. St Louis, MO: Elsevier; 2017: khaolo ea 24.

Salvatore D, Cohen R, Kopp PA, Larsen PR. Thyroid pathophysiology le tlhahlobo ea tlhahlobo. Ka: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, bahlophisi. Buka ea Williams ea Endocrinology. La bo14 la ed. Philadelphia, PA: Elsevier; 2020: khaolo ea 11.

Weiss RE, Refetoff S. Teko ea ts'ebetso ea qoqotho. Ka: Jameson JL, De Groot LJ, oa Kretser DM, et al, eds. Endocrinology: Batho ba baholo le bana. La 7th. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 78.

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