Multiple system system atrophy - mofuta oa parkinsonia
Multiple system system atrophy- parkinsonia mofuta (MSA-P) ke boemo bo sa tloaelehang bo bakang matšoao a ts'oanang le lefu la Parkinson. Leha ho le joalo, batho ba nang le MSA-P ba na le tšenyo e atileng haholo karolong ea sistimi ea methapo e laolang mesebetsi ea bohlokoa joalo ka lebelo la pelo, khatello ea mali le ho fufuleloa.
Karolo e 'ngoe ea MSA ke MSA-cerebellar. E ama haholo-holo libaka tse tebileng bokong, ka holim'a mokokotlo oa mokokotlo.
Lebaka la MSA-P ha le tsejoe. Libaka tse amehileng tsa boko lia kopana le libaka tse anngoeng ke lefu la Parkinson, tse nang le matšoao a tšoanang. Ka lebaka lena, karoloana ena ea MSA e bitsoa parkinsonian.
MSA-P hangata e fumanoa ho banna ba baholo ho feta 60.
MSA e senya tsamaiso ea methapo. Lefu lena le atisa ho tsoela pele ka potlako. Hoo e ka bang halofo ea batho ba nang le MSA-P ba lahlile boholo ba litsebo tsa bona tsa motlakase nakong ea lilemo tse 5 ho tloha ha lefu lena le qala.
Matšoao a ka kenyelletsa:
- Litšisinyeho
- Mathata a motsamao, joalo ka ho lieha, ho lahleheloa ke botsitso, ho thekesela ha u tsamaea
- Ho oa khafetsa
- Ho opeloa ke mesifa le bohloko (myalgia), le ho satalla
- Liphetoho tsa sefahleho, joalo ka ponahalo e kang ea sefahleho sefahlehong le ho qamaka
- Ho thata ho hlafuna kapa ho metsa (nako le nako), ho se khone ho koala molomo
- Ho sitisoa mekhoa ea ho robala (hangata nakong ea ho sisinyeha ha mahlo ka potlako [REM] ho robala bosiu haholo)
- Ho tsekela kapa ho akheha ha o ema kapa ka mora ho ema o tsitsitse
- Mathata a ho emisa
- Ho lahleheloa ke taolo holim'a mala kapa senya
- Mathata ka tšebetso e hlokang motsamao o monyane (tahlehelo ea tsebo e ntle ea makoloi), joalo ka ho ngola ho nyane ebile ho le thata ho a bala
- Ho fufuleloa karolong efe kapa efe ya mmele
- Fokotseha tšebetsong ea kelello
- Ho nyekeloa le mathata a ho senya lijo
- Mathata a boemo ba mmele, joalo ka ho hloka botsitso, ho inama, kapa ho thella
- Pono ea fetoha, ho fokotseha kapa ho fifala
- Liphetoho tsa lentsoe le puo
Matšoao a mang a ka hlahang ka lefu lena:
- Pherekano
- Dementia ea kelello
- Ho tepella maikutlo
- Mathata a ho hema a amanang le boroko, ho kenyelletsa ho koaleha moea ka nakoana borokong kapa ho koaleha moea o lebisang molumo o thata o sisinyehang
Mofani oa hao oa tlhokomelo ea bophelo o tla u hlahloba, 'me au hlahlobe mahlo, methapo le mesifa.
Khatello ea mali ea hau e tla nkoa ha u ntse u robetse u eme.
Ha ho na liteko tse ikhethang tse netefatsang lefu lena. Ngaka e sebetsanang le sistimi ea methapo (neurologist) e ka etsa hore lefu lena le hlahlojoe ho latela:
- Nalane ea matšoao
- Liphetho tsa tlhahlobo ea 'mele
- Ho busa lisosa tse ling tsa matšoao
Ho lekoa ho thusa ho netefatsa hore na lefu lena le fumanoa joang ho ka kenyelletsa:
- MRI ea hlooho
- Maemo a plasma norepinephrine
- Ho hlahlojoa moroto bakeng sa lihlahisoa tsa ho senyeha ha norepinephrine (catecholamines ea moroto)
Ha ho na pheko bakeng sa MSA-P. Ha ho na mokhoa o tsebahalang oa ho thibela lefu lena ho mpefala. Morero oa kalafo ke ho laola matšoao.
Meriana ea Dopaminergic, e kang levodopa le carbidopa, e ka sebelisoa ho fokotsa ho thothomela ha nakoana kapa ka bonolo.
Empa, bakeng sa batho ba bangata ba nang le MSA-P, meriana ena ha e sebetse hantle.
Meriana e ka sebelisoa ho alafa khatello e tlase ea mali.
Mochine oa pacemaker o etselitsoeng ho susumetsa pelo hore e otle ka lebelo le potlakileng (ka lebelo ho feta likotlo tse 100 ka motsotso) o ka eketsa khatello ea mali ho batho ba bang.
Ho sokela ho ka phekoloa ka lijo tse nang le fiber e ngata le litlolo tsa ho hlatsoetsa. Ho na le meriana ea ho alafa mathata a ho tsoha.
Lintlha tse ling le tšehetso bakeng sa batho ba nang le MSA-P le malapa a bona li ka fumanoa ho:
- Mokhatlo oa Naha oa Mathata a Rare - rarediseases.org/rare-diseases/multiple-system-atrophy
- Mokhatlo oa MSA - www.multiplesystematrophy.org/msa-resource/
Sephetho sa MSA ha se hantle. Ho lahleheloa ke mesebetsi ea kelello le ea 'mele butle-butle ho mpefala. Ho ka etsahala hore lefu la pele. Batho ba phela lilemo tse 7 ho isa ho tse 9 kamora ho fumanoa.
Bitsa mofani oa hau haeba u ba le matšoao a lefu lena.
Bitsa mofani oa hau haeba u fumanoe u e-na le MSA mme matšoao a hau a khutla kapa a mpefala. Letsetsa hape haeba matšoao a macha a hlaha, ho kenyeletsoa litlamorao tse ka bang teng tsa meriana, joalo ka:
- Liphetoho tlhokomelong / boits'oarong / maikutlo
- Boitšoaro ba bolotsana
- Botsoa
- Litlelase
- Mekhatlo ea boithatelo
- Ho lahleheloa ke ts'ebetso ea kelello
- Ho nyekeloa kapa ho hlatsa
- Pherekano e matla kapa ho ferekana maikutlo
Haeba u na le setho sa lelapa se nang le MSA 'me boemo ba bona bo theoha hoo u sitoang ho hlokomela motho eo lapeng, batla boeletsi ho mofani oa setho sa lelapa la hau.
Shy-Drager lefu; Hypotension ea methapo ea pelo; Shy-McGee-Drager lefu; Parkinson hammoho le lefu; MSA-P; MSA-C
- Sisteme ea methapo e bohareng le methapo ea methapo
Fanciulli A, Wenning GK. Multiprime-system atrophy. N Engl J Med. 2015; 372 (3): 249-263. PMID: 25587949 pubmed.ncbi.nlm.nih.gov/25587949/.
Lefu la Jankovic J. Parkinson le mathata a mang a motsamao. Ka: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, bahlophisi. Neurology ea Bradley ho Tloaelo ea Bongaka. La 7th. Philadelphia, PA: Elsevier; 2016: khaolo ea 96.
Romero-Ortuno R, Wilson KJ, Hampton JL. Mathata a tsamaiso ea methapo e ikemetseng. Ka: Tlatsa HM, Rockwood K, Young J, eds. Brocklehurst’s Textbook of Geriatric Medicine le Gerontology. La 8th. Philadelphia, PA: Elsevier; 2017: khaolo ea 63.