Neurosyphilis

Neurosyphilis ke tšoaetso ea baktheria ea boko kapa lesapo la mokokotlo. Hangata e hlaha ho batho ba nang le syphilis e sa alafshoang ka lilemo tse ngata.

Neurosyphilis e bakoa ke Treponema pallidum. Hona ke baktheria e bakang syphilis. Neurosyphilis hangata e hlaha lilemo tse ka bang 10 ho isa ho tse 20 kamora hore motho a tšoaetsoe ke syphilis ka lekhetlo la pele. Ha se motho e mong le e mong ea nang le syphilis ea hlahisang bothata bona.

Ho na le mefuta e mene e fapaneng ea neurosyphilis:

• Asymptomatic (foromo e tloaelehileng haholo)
• Kakaretso paresis
• Meningovascular
• Litaele dorsalis

Asymptomatic neurosyphilis e hlaha pele ho syphilis e nang le matšoao. Asymptomatic e bolela hore ha ho na matšoao.

Hangata matšoao a ama tsamaiso ea methapo. Ho ipapisitse le mofuta oa neurosyphilis, matšoao a ka kenyelletsa efe kapa efe ea tse latelang:

• Ho tsamaea ka tsela e sa tloaelehang (gait), kapa ho sitoa ho tsamaea
• Ho ba boqomane menoaneng ea maoto, maotong kapa maotong
• Mathata a ho nahana, joalo ka pherekano kapa ho se tsepamise mohopolo hantle
• Mathata a kelello, joalo ka khatello ea maikutlo kapa ho teneha kapele
• Ho tšoaroa ke hlooho, ho oa kapa ho ba molala o sataletseng
• Ho lahleheloa ke taolo ea senya (incontinence)
• Ho thothomela, kapa bofokoli
• Mathata a pono, esita le bofofu

Mofani oa hao oa tlhokomelo ea bophelo o tla etsa tlhahlobo ea 'mele' me a ka fumana tse latelang:

• Maikutlo a sa tloaelehang
• Ho fokola ha mesifa
• Ho fokotsa mesifa
• Liphetoho tsa kelello

Liteko tsa mali li ka etsoa ho fumana lintho tse hlahisoang ke baktheria tse bakang syphilis, ho kenyelletsa:

• Treponema pallidum thlahlobo agglutination assay (TPPA)
• Teko ea lipatlisiso tsa lefu la Venereal (VDRL)
• Fluorescent treponemal antibody absorption (FTA-ABS)
• Reagin e potlakileng ea plasma (RPR)

Ka neurosyphilis, ho bohlokoa ho hlahloba mokelikeli oa mokokotlo bakeng sa matšoao a syphilis.

Liteko tsa ho batla mathata ka sistimi ea methapo li ka kenyelletsa:

• Angiogram bokong
• Hlooho ea CT scan
• Lumbar puncture (spinal tap) le tlhahlobo ea cerebrospinal fluid (CSF)
• Tlhatlhobo ea MRI ea boko, brainstem, kapa lesapo la mokokotlo

Penicillin ea lithibela-mafu e sebelisetsoa ho phekola neurosyphilis. E ka fanoa ka mekhoa e fapaneng:

• Entsoa ka methapong makhetlo a 'maloa ka letsatsi matsatsi a 10 ho isa ho a 14.
• Ka molomo makhetlo a mane ka letsatsi, ho kopantsoe le liente tsa letsatsi le letsatsi tsa mesifa, tse nkoang matsatsi a 10 ho isa ho a 14.

U tlameha ho etsa liteko tsa mali tse latelang ka likhoeli tse 3, 6, 12, 24 le 36 ho netefatsa hore ts'oaetso e felile. U tla hloka li-lumbar tse latelang bakeng sa tlhahlobo ea CSF likhoeling tse ling le tse ling tse 6. Haeba u na le HIV / AIDS kapa boemo bo bong ba bongaka, lenane la hau la ho latela le ka 'na la fapana.

Neurosyphilis ke bothata bo sokelang bophelo ba syphilis. Hore na o sebetsa hantle hakae ho latela hore na neurosyphilis e matla hakae pele ho kalafo. Morero oa kalafo ke ho thibela ho senyeha ho eketsehileng. Bongata ba liphetoho tsena ha li fetohe.

Matšoao a ka mpefala butle-butle.

Bitsa mofani oa hau haeba o kile oa ba le syphilis nakong e fetileng mme joale o na le matšoao a mathata a sistimi ea methapo.

Ho hlahlojoa ka potlako le kalafo ea ts'oaetso ea pele ea syphilis ho ka thibela neurosyphilis.

Syphilis - neurosyphilis

• Sisteme ea methapo e bohareng le methapo ea methapo
• Syphilis ea morao-rao

Euerle BD. Ho phunya mokokotlo le tlhahlobo ea mokelikeli oa cerebrospinal. Ka: Roberts JR, Custalow CB, Thomsen TW, li-eds. Mekhoa ea Tleliniking ea Roberts le Hedges ho Meriana ea Tšohanyetso le Tlhokomelo e Ntle. La 7th. Philadelphia, PA: Elsevier; 2019: khaolo ea 60.

Setsi sa Naha sa Mathata a Neurological le webosaete ea Stroke. Neurosyphilis. www.ninds.nih.gov/Disorders/All-Disorders/Neurosyphilis-Information-Page. E ntlafalitsoe ka la 27 Hlakubele 2019. E fihlile ka la 19 Hlakola 2021.

Radolf JD, Tramont EC, Salazar JC. Syphilis (Treponema pallidum). Ka: Bennett JE, Dolin R, Blaser MJ, bahlophisi. Mandell, Douglas, le Bennett's Principles and Practice of Infectious Diseases. La 9th. Philadelphia, PA: Elsevier; 2020: khaolo ea 237.