Mucormycosis

Mucormycosis ke tšoaetso ea fungal ea lisono, boko kapa matšoafo. E etsahala ho batho ba bang ba nang le boits'ireletso ba mmele bo fokolang.

Mucormycosis e bakoa ke mefuta e fapaneng ea li-fungus tse atisang ho fumanoa linthong tse bolileng. Tsena li kenyelletsa bohobe bo senyehileng, litholoana le meroho, hammoho le liqubu tsa mobu le manyolo ka litlama. Batho ba bangata ba kopana le fungus ka nako e itseng.

Leha ho le joalo, batho ba nang le boits'ireletso ba mmele bo fokolang ba na le monyetla oa ho ba le mucormycosis. Tsena li kenyelletsa batho ba nang le maemo a latelang:

• AIDS
• Chesa
• Lefu la tsoekere (hangata le laoloang hampe)
• Lefuemia le lymphoma
• Tšebeliso ea steroid ea nako e telele
• Metabolic acidosis
• Phepo e fosahetseng (khaello ea phepo e nepahetseng)
• Ts'ebeliso ea meriana e meng

Mucormycosis e ka kenyelletsa:

• Lefu la sinus le boko le bitsoang ts'oaetso ea rhinocerebral: E kanna ea qala joalo ka tšoaetso ea sinus, ebe e lebisa ho ruruheng ha methapo e tsoang bokong.E ka baka le maqeba a mali a thibelang methapo bokong.
• Tšoaetso ea matšoafo e bitsoang pulmonary mucormycosis: Pneumonia e mpefala kapele mme e ka namela sefubeng, pelong le bokong.
• Likarolo tse ling tsa 'mele: Mucormycosis ea pampiri ea meno, letlalo le liphio.

Matšoao a rhinocerebral mucormycosis a kenyelletsa:

• Mahlo a ruruhang le ho tsoa (a hlahella)
• Ho hlaba lefifi masobeng a nko
• Feberu
• Ho opeloa ke hlooho
• Boemo ba kelello boa fetoha
• Bofubelu ba letlalo kaholimo ho libe
• Bohloko ba sinus kapa pherekano

Matšoao a matšoafo (pulmonary) mucormycosis a kenyelletsa:

• Khohlela
• Ho khohlela mali (ka linako tse ling)
• Feberu
• Phefumoloho e khutšoanyane

Matšoao a gastrointestinal mucormycosis a kenyelletsa:

• Bohloko ba mpeng
• Mali malulong
• Letšollo
• Ho hlatsa madi

Matšoao a liphio (renal) mucormycosis a kenyelletsa:

• Feberu
• Bohloko bo ka mpeng kapa mokokotlong

Matšoao a letlalo (cutaneous) mucormycosis a kenyelletsa sebaka se le seng, se bohloko ka linako tse ling, se thata sa letlalo se ka bang le setsi se fifetseng.

Mofani oa hao oa tlhokomelo ea bophelo o tla u hlahloba. Bona ngaka ea tsebe-nko (ENT) haeba u na le mathata a sinus.

Ho etsa liteko ho latela matšoao a hau, empa ho ka kenyelletsa liteko tsena tsa ho nka litšoantšo:

• Lisebelisoa tsa CT
• MRI e hlahloba

Biopsy e tlameha ho etsoa ho fumana mucormycosis. Biopsy ke ho tlosa karoloana e nyane bakeng sa tlhahlobo ea laboratori ho khetholla fungus le tlhaselo ea lisele tse amohelang.

Ho buuoa ho lokela ho etsoa hang hang ho tlosa lisele tsohle tse shoeleng le tse nang le tšoaetso. Ho buoa ho ka lebisa ho senyeheng hobane ho ka kenyelletsa ho tlosoa ha mahalapa, likarolo tsa nko kapa likarolo tsa leihlo. Empa, ntle le ts'ebetso e matla joalo, menyetla ea ho phela e fokotsehile haholo.

Hape o tla fumana moriana o thibelang mafu, hangata e le amphotericin B, ka mothapo. Kamora hore tšoaetso e laoloe, o ka fetisetsoa moriana o fapaneng o kang posaconazole kapa isavuconazole.

Haeba u na le lefu la tsoekere, ho tla ba bohlokoa ho isa tsoekere maling a hau ka mokhoa o tloaelehileng.

Mucormycosis e na le sekhahla se phahameng haholo sa lefu, leha ho etsoa opereishene e matla. Kotsi ea lefu e latela sebaka sa 'mele se amehang le bophelo ba hau ka kakaretso.

Mathata ana a ka hlaha:

• Ho foufala (haeba ho ameha methapo ea mahlo)
• Ho koala kapa ho koala methapo ea mali ea boko kapa ea matšoafo
• Lefu
• Tšenyo ea methapo

Batho ba nang le boits'ireletso ba mmele bo fokolang le mathata a mmele a ho itšireletsa mafung (ho kenyeletsoa lefu la tsoekere) ba lokela ho ea ngakeng haeba ba ka hlaha:

• Feberu
• Ho opeloa ke hlooho
• Bohloko ba sinus
• Ho ruruha ha mahlo
• E meng ea matšoao a mang a thathamisitsoeng kaholimo

Hobane li-fungus tse bakang mucormycosis li atile, tsela e molemohali ea ho thibela tšoaetso ena ke ho ntlafatsa taolo ea mafu a amanang le mucormycosis.

Tšoaetso ea fungal - mucormycosis; Zygomycosis

• Li-fungus

Litsi tsa Taolo le Thibelo ea Maloetse. Mucormycosis. www.cdc.gov/fungal/diseases/mucormycosis/index.html. E ntlafalitsoe ka la 28 Mphalane 2020. E fihlile ka la 18 Hlakola 2021.

Kontoyiannis DP. Mucormycosis. Ka: Goldman L, Schafer AI, li-eds. Phekolo ea Goldman-Cecil. La 26th. Philadelphia, PA: Elsevier; 2020: khaolo ea 320.

Kontoyiannis DP, Lewis RE. Mahlahana a mucormycosis le entomophthoramycosis. Ka: Bennett JE, Dolin R, Blaser MJ, bahlophisi. Mandell, Douglas, le Bennett's Principles and Practice of Infectious Diseases. La 9th. Philadelphia, PA: Elsevier; 2020: khaolo ea 258.