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Letsatsi La Creation: 25 Hlakubele 2021
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Understanding Autoimmune Thyroid Disease
Video: Understanding Autoimmune Thyroid Disease

Chronic thyroiditis e bakoa ke karabelo ea sesole sa 'mele khahlanong le qoqotho ea qoqotho. Hangata ho fella ka ho fokotsa ts'ebetso ea qoqotho (hypothyroidism).

Lefu lena le boetse le bitsoa lefu la Hashimoto.

Tšoelesa ea qoqotho e molaleng, ka holimo feela moo masapo a molala oa hau a kopanang teng bohareng.

Lefu la Hashimoto ke boloetse bo tloaelehileng ba qoqotho ea qoqotho. E ka etsahala ka lilemo tsohle, empa hangata e bonoa ho basali ba lilemong tse mahareng. E bakoa ke karabelo ea sesole sa 'mele khahlanong le qoqotho ea qoqotho.

Lefu lena le qala butle butle. Ho ka nka likhoeli kapa esita le lilemo hore boemo bona bo fumanoe le hore litekanyo tsa lihormone tsa qoqotho li theohe ho feta tse tloaelehileng. Lefu la Hashimoto le atile haholo bathong ba nang le nalane ea lefu la qoqotho lelapeng.

Maemong a sa tloaelehang, lefu lena le ka amana le mathata a mang a li-hormone a bakoang ke sesole sa 'mele. E ka hlaha ka ts'ebetso e mpe ea adrenal le mofuta oa 1 oa lefu la tsoekere. Maemong ana, boemo bona bo bitsoa mofuta oa 2 polyglandular autoimmune syndrome (PGA II).


Hangata (hangata ho bana), lefu la Hashimoto le hlaha e le karolo ea boemo bo bitsoang mofuta oa 1 polyglandular autoimmune syndrome (PGA I), hammoho le:

  • Ts'ebetso e mpe ea litšoelesa tsa adrenal
  • Mafu a fungal a molomo le lipekere
  • Tšoelesa e sa sebetseng ea parathyroid

Matšoao a lefu la Hashimoto a ka kenyelletsa tse latelang:

  • Ho sokela
  • Ho thata ho tsepamisa mohopolo kapa ho nahana
  • Letlalo le ommeng
  • Ho atolosoa molala kapa boteng ba goiter, e kanna ea ba eona feela matšoao a pele
  • Mokhathala
  • Ho hlotheha ha moriri
  • Linako tse boima kapa tse sa tloaelehang
  • Ho se mamellane le serame
  • Boima bo bonolo
  • Tšoelesa ea qoqotho e nyane kapa e shrunken (kamora lefu lena)

Liteko tsa laboratori ho fumana ts'ebetso ea qoqotho li kenyelletsa:

  • Teko ea mahala ea T4
  • Serum TSH
  • Kakaretso ea T3
  • Li-autoantibodies tsa qoqotho

Lithuto tsa ho etsa litšoantšo le biopsy e ntle ea nale ha ho hlokahale hore ho fumanoe Hashimoto thyroiditis.

Lefu lena le ka fetola sephetho sa liteko tse latelang:


  • Palo e felletseng ea mali
  • Serum prolactin
  • Serame ea sodium
  • Kakaretso ea k'holeseterole

Hypothyroidism e sa alafshoang e ka fetola tsela eo 'mele oa hau o sebelisang meriana eo u ka e sebelisang maemong a mang, joalo ka lefu la sethoathoa. Mohlomong u tla hloka liteko tsa mali khafetsa ho lekola maemo a meriana 'meleng oa hau.

Haeba ho na le lintho tse fumanoeng ka qoqotho e sa sebetseng hantle, u ka fumana meriana e ncha ea qoqotho.

Ha se motho e mong le e mong ea nang le thyroiditis kapa goiter ea nang le lihormone tse tlase tsa qoqotho. U kanna ua hloka ts'alo-morao khafetsa ke mofani oa tlhokomelo ea bophelo.

Lefu lena le lula le tsitsitse ka lilemo. Haeba e tsoela pele butle-butle ho haelloa ke lihomone tsa qoqotho (hypothyroidism), e ka alafshoa ka kalafo ea li-hormone.

Boemo bona bo ka hlaha ka mathata a mang a autoimmune. Maemong a sa tloaelehang, mofets'e oa qoqotho kapa thyroid lymphoma e ka hlaha.

Ha hypothyroidism e sa alafshoang e ka lebisa phetohong ea tsebo, coma le lefu. Hangata sena se etsahala haeba batho ba fumana tšoaetso, ba tsoa likotsi, kapa ba noa meriana, joalo ka li-opioid.


Bitsa mofani oa hau haeba u ba le matšoao a thyroiditis a sa foleng kapa hypothyroidism.

Ha ho na mokhoa o tsebahalang oa ho thibela lefu lena. Ho tseba lisosa tsa kotsi ho ka lumella ho hlahlojoa le kalafo pejana.

Hashimoto thyroiditis; E sa foleng ea lymphocytic thyroiditis; Ho itšireletsa mafung; Sa foleng autoimmune thyroiditis; Lymphadenoid goiter - Hashimoto; Hypothyroidism - Hashimoto; Mofuta oa 2 polyglandular autoimmune syndrome - Hashimoto; PGA II - Hashimoto

  • Litšoelesa tsa endocrine
  • Ho atolosoa ha qoqotho - scintiscan
  • Lefu la Hashimoto (chronic thyroiditis)
  • Tšoelesa ea qoqotho

Amino N, Lazaro JH, De Groot LJ. Chronic (Hashimoto's) thyroiditis. Ka: Jameson JL, De Groot LJ, oa Kretser DM, et al, eds. Endocrinology: Batho ba baholo le bana. La 7th. Philadelphia, PA: Elsevier Saunders; 2016: khaolo ea 86.

Brent GA, Weetman AP. Hypothyroidism le thyroiditis. Ka: Melmed S, Auchus RJ, Golfine AB, Koenig RJ, Rosen CJ, bahlophisi. Buka ea Williams ea Endocrinology. La bo14 la ed. Philadelphia, PA: Elsevier; 2020: khaolo ea 13.

Jonklaas J, Bianco AC, Bauer AJ, le al. Litaelo tsa kalafo ea hypothyroidism: e hlophisitsoeng ke sehlopha sa basebetsi ba American Thyroid Association mabapi le phetoho ea lihormone tsa qoqotho. Thyroid. 2014; 24 (12): 1670-1751. PMID: 25266247 e fetotsoe.ncbi.nlm.nih.gov/25266247/.

Lakis ME, Wiseman D, Kebebew E. Tsamaiso ea thyroiditis. Ka: Cameron AM, Cameron JL, bahlophisi. Phekolo ea Hajoale ea Ts'ebetso. 13th ed. Philadelphia, PA: Elsevier; 2020: 764-767.

Marcdante KJ, Kliegman RM. Boloetse ba qoqotho. Ka: Marcdante KJ, Kliegman RM, bahlophisi. Nelson Bohlokoa ba Pediatrics. La 8th. Elsevier; 2019: khaolo ea 175.

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