Phekolo ea Regenokine ke eng mme ea sebetsa?
Litaba
- Regenokine ke eng?
- Tsamaiso ea Regenokine e kenyelletsa eng?
- Mali a hau a tla huloa
- Mali a hau a tla sebetsoa
- Mali a hau a tla khutlisetsoa lenonyellong le amehileng
- Ha ho nako ea phomolo ea phomolo e hlokahalang
- Regenokine e sebetsa joang?
- Regenokine e ea sebetsa?
- Hobaneng Regenokine e sa sebetse bakeng sa motho e mong le e mong?
- Seo lithuto li reng
- Ke batho ba bakae ba kileng ba phekoloa?
- Ho thoe'ng ka ho nchafala ha lefufuru?
- Phapang ke efe lipakeng tsa kalafo ea Regenokine le PRP?
- Regenokine e sebelisa regimen ea ts'ebetso e ts'oanang
- Regenokine e tlosa lisele tsa mali le lisebelisoa tse ling tse ka bang kotsi
- Regenokine e bolokehile?
- Regenokine e bitsa bokae?
- Ha e koaheloe ke inshorense United States
- Kalafo ea Regenokine e nka nako e kae?
- Nka fumana mofani oa thepa ea tšoanelehang kae?
- Tsa Tsau-tsau
Regenokine ke kalafo e khahlano le ho ruruha bakeng sa bohloko ba manonyeletso le ho ruruha. Ts'ebetso e kenya li-protein tse molemo tse bokelletsoeng maling a hau manonyellong a hau a amehileng.
Kalafo e entsoe ke Dr. Peter Wehling, ngaka e buoang ea mokokotlo ea Jeremane, mme e se e lumelletsoe ho sebelisoa Jeremane. Baatlelete ba bangata ba hlahelletseng, ho kenyeletsoa Alex Rodriguez le Kobe Bryant, ba etetse Jeremane bakeng sa kalafo ea Regenokine mme ba tlaleha hore e kokobetsa bohloko.
Le ha Regenokine e e-so lumelloe ke Tsamaiso ea Lijo le Lithethefatsi (FDA), e sebelisoa e sa ngolisoe libakeng tse tharo United States tse nang le laesense ke Wehling.
Regenokine e ts'oana le kalafo ea platelet-rich plasma (PRP), e sebelisang lihlahisoa tsa hau tsa mali ho thusa ho nchafatsa lisele sebakeng se lemetseng.
Sehloohong sena, re tla hlahloba hore na mokhoa oa Regenokine o joang, o fapane joang le PRP, le hore na o sebetsa joang bakeng sa phomolo ea bohloko.
Regenokine ke eng?
Qalong ea hae ea pele ea Regenokine, Wehling o ile a sebetsana ka katleho le lipere tsa Arabia tse neng li bile le likotsi tse kopaneng. Kamora ho ntšetsa pele lipatlisiso tsa hae le batho, tlhahiso ea Wehling e ile ea amoheloa hore e sebelisoe ke batho ka 2003 ke Jeremane e lekanang le FDA.
Tsamaiso e tsepamisa liprotheine maling a hao tse loantšang ho ruruha le ho khothaletsa nchafatso. Serum e sebetsitsoeng e ntoo khutlisetsoa lenonyong le amehileng. Serum ha e na lisele tse khubelu tsa mali kapa lisele tse tšoeu tsa mali tse ka bakang ho teneha.
Serum e ka boela ea bitsoa serum e nang le boemo ba autologous, kapa ACS.
Tsamaiso ea Regenokine e kenyelletsa eng?
Pele ho ts'ebetso, setsebi sa Regenokine se tla sebetsa le mofani oa hau oa mantlha oa tlhokomelo ea bophelo ho fumana hore na u mokhethoa ea hantle oa kalafo ena. Ba tla etsa boikemisetso ba bona ka ho hlahloba tšebetso ea hau e tloaelehileng ea mali le litlhahlobo tsa litšoantšo tsa kotsi ea hau.
Haeba u fumana tsoelo-pele, mona ke seo u ka se lebellang nakong ea ts'ebetso:
Mali a hau a tla huloa
Ngaka e tla hula mali a mabeli ka letsohong la hao. Sena se nka metsotso e 'maloa feela.
Mali a hau a tla sebetsoa
Mocheso oa sampole ea hau ea mali o tla nyoloha hanyane hofihlela ho lihora tse 28 tikolohong e nyopa. E tla beoa centrifuge ho:
- arola lihlahisoa tsa mali
- tsepamisa mohopolo liprotheine tse khahlanong le ho ruruha
- theha seramu e se nang sele
Ho latela boemo ba hau, liprotheine tse ling li ka eketsoa serumeng.
Ho ea ka Dr. Jana Wehling, ngaka ea masapo le ea ho tsieleha ea sebetsang le ntate oa hae tleliniking ea Regenokine e Dusseldorf, Jeremane, “Ho eketsoa serumeng ena ho kopanyelletsa liprotheine tse kopanyang tse kang IL-1 Ra, likokoana-hloko tsa moo, kapa cortisone ea tekanyo e tlaase.”
Sampole e tšoaroang e hoamisoa ebe e kenngoa ka lijing tsa ente.
Mali a hau a tla khutlisetsoa lenonyellong le amehileng
Ts'ebetso ea ho hlaphoheloa hape e nka metsotso e 'maloa. Peter Wehling o sa tsoa hlahisa mokhoa oa ente e le 'ngoe (Regenokine® One Shot), sebakeng sa ente e le' ngoe letsatsi ka leng bakeng sa matsatsi a 4 kapa a mahlano.
Ngaka e ka sebelisa ultrasound e le thuso ea ho nka litšoantšo ho beha sebaka sa ente ka nepo.
Haeba serum e setse, e ka emisoa hore e tle e sebelisoe nakong e tlang.
Ha ho nako ea phomolo ea phomolo e hlokahalang
Ha ho na nako ea phomolo e latelang ts'ebetso. U tla tseba ho qalella mesebetsi ea hau hanghang kamora ho khutlisa.
Nako eo u e nkang hore u utloe phomolo bohlokong le ho ruruheng e fapana ka bomong.
Regenokine e sebetsa joang?
Ho ea ka Peter Wehling, seramu e phekotsoeng ea Regenokine e na le makhetlo a fetang 10 000 a protheine e khahlano le ho ruruha. Protheine ena, e tsejoang ka hore ke interleukin-1 receptor antagonist (IL-1 Ra), e thibela molekane oa eona ea bakang ho ruruha, interleukin 1.
Dr. Christopher Evans, motsamaisi oa Rehabilitation Medicine Research Center ea Mayo Clinic, o e hlalositse ka tsela ena: “‘ Interleukin e mpe, ’e leng interleukin 1, e kopana le ntho e amohelang mokelikeli o itseng ka holim’a sele e e arabelang. E emisa moo. Ka mor'a moo, lintho tsohle tse mpe li etsahala. ”
Evans o ile a tsoela pele a re: "Interleukin e ntle ke sesebelisoa sa li-interleukin-1 receptor antagonist. Sena se thibela mokelikeli oa (cell's). … Sele ha e bone interleukin-1, hobane e koetsoe, ka hona, lintho tse mpe ha li etsahale. "
Ho nahanoa hore IL-1 Ra e kanna ea loants'a lintho tse lebisang lefufung le ho senyeha ha lisele le osteoarthritis.
Regenokine e ea sebetsa?
Boithuto ba Regenokine bo bonts'a hore bo ea sebetsa ho batho ba bangata, empa eseng kaofela.
Boitsebiso ba tleliniki ea Wehling bo bolela hore ba nka kalafo ea Regenokine e atleha ha bohloko ba mokuli kapa tšebetso li ntlafala ka liperesente tse 50. Ba sebelisa lipotso tse tloaelehileng bakeng sa batho ba nang le kalafo ho lekanya phello ea eona.
Tleliniki e hakanya hore hoo e ka bang liperesente tse 75 tsa batho ba nang le lefu la masapo le manonyeletso mahareng a bohato ba tla atleha kalafo.
Lingaka tsa U.S. tse filoeng tumello ea ho sebelisa Regenokine li na le sekhahla se tšoanang sa katleho. Ho bonts'itsoe ho chechisa tlhoko ea sebaka sa kopanelo, kapa ho qoba tlhoko ea sebaka se kopaneng ho batho ba bang.
Hobaneng Regenokine e sa sebetse bakeng sa motho e mong le e mong?
Re ile ra botsa Evans, ea neng a sebetsa le Peter Wehling pejana ho lipatlisiso tsa hae, hore na hobaneng Regenokine e sebeletsa batho ba bangata empa e seng bohle. Mona ke seo a se buileng:
“Osteoarthritis hase lefu le le leng le tšoanang le leo. E hlaha ka mefuta e mengata 'me ho ka etsahala hore ebe ho na le likaroloana tse fapaneng, tse ling tsa tsona li tla arabela,' me tse ling li se ke tsa arabela. Dr. Wehling o hlahisitse algorithm bakeng sa sena a sebelisa likarolo tse fapaneng tsa DNA ea mokuli. Ho ile ha boleloa hore batho ba nang le tatellano e itseng ea DNA ba tla arabela hamolemo. ”
Dr. Thomas Buchheit, MD, CIPS, motsamaisi oa Phekolo ea Mahlaba a Ikarabellang Univesithing ea Duke - e 'ngoe ea libaka tse tharo United States tse nang le lengolo la tumello ea ho sebelisa serame e entsoeng ke Wehling - o boetse a re, "Re bona litholoana tse ntle ka ho fetesisa ho batho ke na le ramatiki e itekanetseng ho isa ho e itekanetseng, eseng lesapo masapong. ”
Seo lithuto li reng
Liphuputso tse nyane li shebile kalafo ea Regenokine, eo hape e bitsoang serum autologous conditioned serum (ACS), bakeng sa bohloko ba manonyeletso. Ba bang ba e bapisa le mekhoa e meng ea phekolo. Lithuto tse ling li sheba manonyeletso a itseng.
Lithuto tse 'maloa tsa morao tjena ke tsena:
- Phuputso ea 2020 ea batho ba 123 ba nang le lefu la masapo a mabeli e bapisa ACS le kalafo ea PRP. Phuputso e fumane hore kalafo ea ACS e sebetsa ebile e "phahametse biochemical ho feta PRP." Batho ba fumaneng ACS ba na le phokotso e bohloko ea bohloko le ts'ebetso ea ts'ebetso ho feta ba nang le PRP.
- Batho ba 28 ba nang le lefu la masapo a mangole kapa a letheka ba fumane hore kalafo ea ACS e hlahisitse "ho theoha ka potlako ha bohloko" le keketseho ea motsamao o fapaneng.
- Moriana oa bohloko ba ho iphetola o bapisa Regenokine le kalafo tse ling tse ikatisang. E tlaleha hore ACS "e fokotsa bohloko le tšenyo e kopaneng ea ramatiki."
- Batho ba 47 ba nang le liso tsa meniscus ba phekotsoeng ba fumane hore ACS e hlahisitse lintlafatso tse kholo kamora likhoeli tse 6. Ka lebaka leo, ho buuoa ho ile ha qojoa liperesente tse 83 tsa linyeoe.
- Mangole a 118 a alafiloeng ka ACS a fumane ntlafatso e potlakileng ea bohloko bo matlafalitsoeng bakeng sa lilemo tse 2 tsa thuto. Ke motho a le mong feela ea fumaneng lengole nakong ea boithuto.
Ke batho ba bakae ba kileng ba phekoloa?
Ho ea ka Jana Wehling, "Lenaneo la Regenokine le 'nile la sebelisoa ke lingaka ka lilemo tse ka bang 10' me bakuli ba hakanyetsoang ba 20,000 ba se ba alafiloe lefats'eng ka bophara."
Moloko oa pele oa Regenokine, Orthokine, o sebelisitsoe ho phekola bakuli ba fetang 100,000, o boletse joalo.
Ho thoe'ng ka ho nchafala ha lefufuru?
Joalokaha Evans a boletse, ho nchafatsoa ha lefufuru ke mohala o halalelang bakeng sa batho ba sebetsang le lefu la masapo. Na regenokine e ka nchafatsa lefufuru? Ke potso e ntseng e hlahlojoa ke Peter Wehling le lab ea hae.
Ha a botsoa ka nchafatso ea lefufuru, Jana Wehling o ile a araba: “Ka 'nete, re na le bopaki bo hlakileng ba mahlale ba ho nchafala ha mesifa le tendon tlasa ACS. Ho na le matšoao a ts'ireletso ea lefufuru hape le nchafatso litekong tsa liphoofolo le ts'ebelisong ea bongaka ea batho, "o boletse joalo.
"Empa ho nchafala ha lefufuru ho thata haholo ho paka lithutong tsa bongaka."
Phapang ke efe lipakeng tsa kalafo ea Regenokine le PRP?
Phekolo ea PRP e hula mali a hao, ee sebelise ho eketsa palo ea liplatelete, ebe e e khutlisetsa sebakeng se amehileng.
Mali a hau a feta ka centrifuge ho tsepamisa liplatelete, empa ha e tlhotliloeng. Ho nahanoa hore bongata ba liplatelete bo thusa ho potlakisa pholiso ea sebaka ka ho lokolla lintlha tse hlokahalang tsa kholo.
PRP ha e so amoheloe ke FDA, mme hangata ha e koaheloe ke inshorense. Litsenyehelo tsa kalafo ea PRP li fapana ho tloha ho $ 500 ho isa ho $ 2,000 ka ente. Leha ho le joalo, e sebelisoa ka toka khafetsa ho phekola maemo a mesifa.
. Arthritis Foundation e re PRP e kanna ea nka likhoeli tse 3 ho isa ho tse 6. E "fetile ebile ka linako tse ling e felisitse liente tsa hyaluronic kapa li-corticosteroid," motheo o boletse.
Ngaka ea masapo Dr. Laura Timmerman o beha taba ka tsela ena: PRP ke “ntho e nepahetseng ho leka pele… empa Regenokine o na le monyetla o motle oa ho folisa mokuli.”
Regenokine e sebelisa regimen ea ts'ebetso e ts'oanang
Joalo ka Regenokine, PRP ke kalafo ea biologic. Empa Regenokine e na le regimen e hlophisitsoeng e sebetsanang le ts'ebetso, ntle le ho se lumellane ho eona, ho bolela Jana Wehling.
Ka lehlakoreng le leng, PRP e lokiselitsoe ka bomong le. Sena se thatafalletsa ho bapisa kalafo lithutong tsa mahlale hobane sebopeho sa PRP se fapana.
Regenokine e tlosa lisele tsa mali le lisebelisoa tse ling tse ka bang kotsi
Ho fapana le Regenokine, PRP ha e na sele. E na le lisele tse tšoeu tsa mali le likarolo tse ling tsa mali tse ka bakang ho ruruha le bohloko ha li entoa, ho latela Dr. Thomas Buchheit, Setsing sa Duke University's Translational Pain Medicine.
Ka lehlakoreng le leng, Regenokine ea hloekisoa.
Regenokine e bolokehile?
Tšireletseho ea Regenokine ha e botsoe, ho latela litsebi tse ngata. Joalokaha Evans ea Mayo Clinic e boletse: “Ntho ea pele eo u lokelang ho e tseba ke hore e sireletsehile. Ho ka buuoa ka mokhoa o hlakileng. ”
Ha ho na litlaleho tsa litlamorao tse mpe lithutong tsa Regenokine.
Ho hlokahala tumello ea FDA hore Regenokine e sebelisoe United States hobane ho nyolloa ha sampole ea hau ea mali e nkoang e le sethethefatsi.
Kamohelo ea FDA e hloka lithuto tse fapaneng le limilione tsa lidolara ho ts'ehetsa lipatlisiso.
Regenokine e bitsa bokae?
Litlhare tsa Regenokine li theko e boima, ho isa ho $ 1,000 ho isa ho $ 3,000 ka ente, ho latela Jana Wehling.
Letoto le felletseng ka karolelano le na le liente tse 'ne ho isa ho tse hlano. Theko hape e fapana ho latela sebaka sa 'mele se alafiloeng le ho rarahana ha eona. Ka mohlala, Jana Wehling o itse, mokokotlong "re kenya manonyeletso a mangata le methapo e potileng nakong e le 'ngoe."
Ha e koaheloe ke inshorense United States
United States, Regenokine e sebelisoa ntle le leibole ke litho tse nang le laesense tsa Peter Wehling. Litheko li latela mokhoa oa Wehling o Dusseldorf, Jeremane, mme kalafo ha e koaheloe ke inshorense.
Ngaka e buoang ea masapo, Timmerman o re o lefisa $ 10,000 bakeng sa letoto la ente lenonyong la pele, empa halofo eo bakeng sa lenonyeletso la bobeli kapa le latelang. O boetse a hlokomela hore ho hula mali ho le leng ho ka u fa lijana tse 'maloa tsa serum tse ka hoamisoang hore o ka li sebelisa hamorao.
Morero o mong le o mong oa kalafo o "etselitsoe moetlo" ho latela litlhoko tsa motho ka mong, ho latela Jana Wehling. Lintho tse ling li ka ama litšenyehelo, joalo ka "mofuta le ho teba ha lefu, boemo ba bohloko ba motho ka mong, litletlebo tsa bongaka, le comorbidities (mafu a neng a le teng pele)."
O hatelletse hore sepheo sa bona ke ho theola theko.
Kalafo ea Regenokine e nka nako e kae?
Hore na Regenokine e hloka ho phetoa ho fapana ka motho ka mong le ka boima ba boemo ba hau. Peter Wehling o hakanya hore phomolo ea ramatiki le letheka e ka nka lilemo tse pakeng tsa 1 le 5.
Batho ba arabelang hantle kalafong hangata ba e pheta lilemo tse ling le tse ling tse 2 ho isa ho tse 4, Peter Wehling o re.
Nka fumana mofani oa thepa ea tšoanelehang kae?
Ofisi ea Peter Wehling e Dusseldorf, Jeremane, e fana ka laesense mme e hlahloba khafetsa lilabakeng tsa lingaka tse fanang ka kalafo ea Regenokine. Ba batla ho netefatsa hore kalafo e etsoa ka nepo le ka mokhoa o ts'oanang.
Boitsebiso ba ho ikopanya le bona bakeng sa tleliniki e Dusseldorf le libaka tse tharo tsa U.S. tse nang le laesense ea ho sebelisa kalafo:
Dr. Wehling & Molekane
Dusseldorf, Jeremane
Peter Wehling, MD, PhD
Imeile: [email protected]
Webosaete: https://drwehlingandpartner.com/en/
Nomoro: 49-211-602550
Lenaneo la kalafo ea bohloko ba Duke Regenerative
Raleigh, North Carolina
LITLHAKISO TSA MOLIMO: Thomas Buchheit, MD
Imeile: [email protected]
Webosaete: dukerptp.org
Nomoro: 919-576-8518
Bophelo ba Span Medicine
Santa Monica, California
Chris Renna, ETSA
Imeile: [email protected]
Webosaete: https://www.lifespanmedicine.com
Nomoro: 310-453-2335
Laura Timmerman, MD
Walnut Creek, California
Imeile: [email protected]
Webosaete: http://lauratimmermanmd.com/-regenokinereg-program.html
Nomoro: 925- 952-4080
Tsa Tsau-tsau
Regenokine ke kalafo ea bohloko bo kopaneng le ho ruruha. Ts'ebetso e sebetsana le mali a hau ho tsepamisa mohopolo liprotheine tse molemo ebe e kenya mali a phekotsoeng sebakeng se amehileng.
Regenokine ke mofuta o matla ho feta kalafo ea platelet e nang le leruo le nang le platelet (PRP), 'me e sebetsa hantle le ho feta nako e telele ho feta PRP.
Regenokine e lumelloa ho sebelisoa Jeremane, moo e ileng ea ntlafatsoa ke Dr. Peter Wehling, empa ha e na tumello ea FDA United States. E sebelisoa e le sieo libakeng tse tharo United States tse nang le laesense ke Wehling.
Ho hlokahala lithuto tse ling ho netefatsa katleho ea Regenokine le ho fumana tumello ea FDA.
Kalafo e bolokehile ebile e ea sebetsa, ho latela lithuto tsa bongaka le litsebi tsa bongaka. Bothata ke hore Regenokine ke kalafo e turang e lokelang ho lefuoa ka pokothong United States.