Li-lymphocyte: seo li leng sona le hore na ke hobaneng li ka fetoloa

Litaba

• Li-lymphocyte tse fetotsoeng
• 1. Li-lymphocyte tse phahameng
• 2. Li-lymphocyte tse tlaase
• Mefuta ea li-lymphocyte
• Li-lymphocyte tse atypical ke eng?

Li-lymphocyte ke mofuta oa sele e itšireletsang 'meleng, e tsejoang hape e le lisele tse tšoeu tsa mali, tse hlahisoang ka bongata ha ho na le ts'oaetso, ka hona ke sesupo se setle sa boemo ba bophelo ba mokuli.

Hangata, palo ea li-lymphocyte e ka hlahlojoa ka tlhahlobo ea mali, 'me ha e holisoa, hangata ke sesupo sa ts'oaetso, ka hona, ho kgothaletswa hore o buisane le ngaka e akaretsang ho fumana bothata le ho qala kalafo e nepahetseng.

Li-lymphocyte tse fetotsoeng

Litekanyetso tse tloaelehileng tsa litšupiso bakeng sa li-lymphocyte li lipakeng tsa li-lymphocyte tse 1000 ho isa ho tse 5000 ka mali a mm, e emelang 20 ho isa ho 50% palong e lekantsoeng, 'me e ka fapana ho latela laboratori eo tlhahlobo e etsoang ho eona. Ha litekanyetso li le kaholimo kapa ka tlase ho boleng ba litšupiso, setšoantšo sa lymphocytosis kapa lymphopenia se khetholloa ka ho latellana.

1. Li-lymphocyte tse phahameng

Palo ea li-lymphocyte tse kaholimo ho litekanyetso tsa litšupiso e bitsoa lymphocytosis mme hangata e amana le lits'ebetso tse tšoaetsanoang. Kahoo, lisosa tsa mantlha tsa li-lymphocyte tse phahameng ke tsena:

• Mafu a hlobaetsang, a kang mononucleosis, pholio, mmasele, rubella, dengue kapa sefuba, mohlala;
• Mafu a sa foleng, a kang lefuba, malaria;
• Hepatitis ea kokoana-hloko;
• Hyperthyroidism;
• Khaello ea mali e tšoaeang khaello ea folic acid le vithamine B12;
• Chefo ea benzene le tšepe e boima;
• Lefu la tsoekere;
• Botenya;
• Ts'oaetso ea mmele.

Ntle le moo, keketseho ea palo ea li-lymphocyte e ka etsahala hape ka lebaka la maemo a mmele, joalo ka bakhachane le masea, ntle le bofokoli ba phepo, joalo ka khaello ea vithamine C, D kapa calcium.

2. Li-lymphocyte tse tlaase

Palo ea li-lymphocyte tse ka tlasa litekanyetso tsa litšupiso e bitsoa lymphopenia mme hangata e amana le maemo a amang moko oa masapo, joalo ka anemia ea mali kapa lefu la kankere ea mali. Ho phaella moo, lymphopenia e ka boela ea e-ba pontšo ea maloetse a ikemetseng, moo 'mele ka boeona o sebetsang khahlanong le sesole sa' mele sa ho itšireletsa mafung, joalo ka systemic lupus erythematosus, mohlala (SLE).

Lymphopenia e ntse e ka etsahala ka lebaka la AIDS, kalafo ea lithethefatsi ea immunosuppressive kapa chemotherapy kapa radiotherapy kalafo, mafu a sa tloaelehang a liphatsa tsa lefutso, kapa e ka ba maemo a khatello, joalo ka postoperative le ho imeloa haholo ke 'mele.

Mefuta ea li-lymphocyte

Ho na le mefuta e 'meli e meholo ea li-lymphocyte' meleng, li-lymphocyte tsa B, e leng lisele tse sa butsoang tse hlahisoang mokong oa masapo ebe li ntšetsoa maling ho hlahisa lithibela-mafu khahlanong le libaktheria, livaerase le li-fungus, le li-lymphocyte tsa T, tse hlahisoang mokong oa masapo. empa e hlahisoang ke thymus ho fihlela e arotsoe ka lihlopha tse 3:

• Li-lymphocyte tsa CD4 T: li thusa li-lymphocyte tsa B ho felisa tšoaetso, e le tlhokomeliso ea pele ea sesole sa 'mele. Hangata tsena ke lisele tsa pele tse anngoeng ke vaerase ea HIV, 'me ho bakuli ba nang le tšoaetso tlhahlobo ea mali e bontša boleng bo ka tlase ho 100 / mm³.
• Li-lymphocyte tsa CD8 T: fokotsa ts'ebetso ea mefuta e meng ea li-lymphocyte, ka hona, ea eketseha maemong a HIV;
• Li-lymphocyte tsa cytotoxic: senya lisele tse sa tloaelehang le ho tšoaetsoa ke livaerase kapa libaktheria.

Leha ho le joalo, liteko tsa mofuta oa li-lymphocyte, haholo-holo tsa mofuta oa CD4 kapa CD8, li tlameha ho hlalosoa kamehla ke ngaka ho lekola hore na ho na le kotsi ea ho ba le HIV, mohlala, hobane mafu a mang le ona a ka baka mofuta o tšoanang oa liphetoho.

Kahoo, haeba ho na le khoao ka ts'oaetso ea HIV, ho bohlokoa hore u etse tlhahlobo ea laboratori e batlang kokoana-hloko ka har'a lisele tsa 'mele. Ithute haholoanyane ka tlhahlobo ea HIV.

Li-lymphocyte tse atypical ke eng?

Li-lymphocyte tse atypical ke li-lymphocyte tse hlahisang mefuta e fapaneng mme li hlaha ka mokhoa o tloaelehileng ha ho na le ts'oaetso, haholo ts'oaetso ea vaerase, joalo ka mononucleosis, herpes, AIDS, rubella le khokonyane. Ntle le ponahalo ea tšoaetso ea vaerase, li-lymphocyte tse atypical li ka tsejoa palong ea mali ha ho na le ts'oaetso ea baktheria, joalo ka lefuba le syphilis, ts'oaetso ea protozoa, joalo ka toxoplasmosis, ha ho na le hypersensitivity ho lithethefatsi kapa maloetse a ikemetseng, joalo ka lupus.

Ka tloaelo palo ea li-lymphocyte tsena e khutlela ho se tloaelehileng (boleng ba litšupiso bakeng sa li-lymphocyte tse atypical ke 0%) ha moemeli ea bakang tšoaetso a felisoa.

Li-lymphocyte tsena li nkuoa e le li-lymphocyte tsa T tse hlahisitsoeng ka karabelo ea li-lymphocyte tsa mofuta oa B tse nang le ts'oaetso mme li etsa mesebetsi e ts'oanang le li-lymphocyte tse tloaelehileng karabong ea 'mele ea ho itšireletsa mafung. Li-lymphocyte tse atypical hangata li kholo ho feta li-lymphocyte tse tloaelehileng mme li fapana ka sebopeho.