Phuputso ea morao-rao mabapi le Endometriosis: Seo U hlokang ho se Tseba

Litaba

• Morao-rao ho phekoleng endometriosis
• Meriana e mecha ea molomo
• Khetho ea ho buoa le teko ea bongaka e tlang
• Tsa morao-rao mabapi le ho tseba endometriosis
• Lipatlisiso tse ling tsa endometriosis li atametse
• Lisele tse ikarabellang
• Phekolo ea Gene
• Tsela

Kakaretso

Endometriosis e ama basali ba hakanngoang. Haeba o phela le endometriosis, o ka nka mehato ea ho sebetsana le matšoao a boemo boo. Ha ho na pheko hona joale, empa bo-ramahlale ba sebetsa ka thata ho ithuta endometriosis le hore na e ka alafshoa hantle joang.

Lilemong tsa morao tjena, sehlopha se ntseng se hola sa lipatlisiso se hlahlobile lisosa tse ka bang teng tsa endometriosis, mekhoa e seng e hlaselang e sebelisetsoang ho hlahloba boemo, le likhetho tsa kalafo ea nako e telele. Bala ho ea pele ho ithuta ka lintlafatso tsa moraorao.

Morao-rao ho phekoleng endometriosis

Tsamaiso ea bohloko ke sepheo sa mantlha sa kalafo tse ngata bakeng sa endometriosis. Hangata ho khothaletsoa meriana ea ngaka le ea kalafo ea bohloko le litlhare tsa lihormone. Ho buoa hape ke khetho ea kalafo.

Meriana e mecha ea molomo

Lehlabuleng la 2018, Tsamaiso ea Lijo le Lithethefatsi ea U.S. (FDA) e amohetse mohanyetsi oa pele oa molomo oa ho lokolla lihormone (GnRH) ho thusa basali ba nang le mahlaba a bohloko ho tloha endometriosis.

Elagolix ke. E sebetsa ka ho emisa tlhahiso ea estrogen. Hormone ea estrogen e thusa ho hola ha matšoao a endometrium le matšoao a sa phutholoheng.

Ho bohlokoa ho hlokomela hore bahanyetsi ba GnRH ha e le hantle ba beha 'mele nakong ea ho khaotsa ho ilela khoeli. Seo se bolela hore litla-morao li ka kenyelletsa tahlehelo ea masapo, masapo a chesang kapa ho omella ka botšehaling har'a tse ling.

Khetho ea ho buoa le teko ea bongaka e tlang

Endometriosis Foundation of America e nka ho buuoa ka "laparoscopic excision" e le tekanyetso ea khauta bakeng sa kalafo ea bongaka ea boemo bona. Morero oa ts'ebetso ena ke ho tlosa liso tsa endometrium ha o ntse o boloka lisele tse phetseng hantle.

Phekolo e ka atleha ho fokotsa bohloko bo amanang le endometriosis, ho bolela tlhahlobo ho koranta ea Women’s Health. Ho a khonahala, ka tumello e fanoeng pele ho tsebo, hore ngaka e buoang e etse opereishene ea ho ts'oaea ho alafa endometriosis e le karolo ea ts'ebetso e ts'oanang ea ho fumana boemo. Phuputso ea 2018 e kenyelletsang barupeluoa ba fetang 4,000 e fumane hore ho buuoa ka laparoscopic excision ho ne ho boetse ho atleha ho phekola bohloko ba pelvic le matšoao a amanang le mala a endometriosis.

Teko e ncha ea bongaka Netherlands e ikemiselitse ho etsa opereishene le ho feta. Taba e le 'ngoe ka mekhoa ea hajoale ea ho buoa ke hore haeba liso tsa endometriosis li sa tlosoe ka botlalo, matšoao a ka khutla. Ha sena se etsahala, opereishene e ka hloka ho phetoa. Teko e ncha ea bongaka e ntse e hlahloba ts'ebeliso ea litšoantšo tsa fluorescence ho thusa ho thibela tlhoko ea ho buuoa khafetsa.

Tsa morao-rao mabapi le ho tseba endometriosis

Ho tloha litlhahlobong tsa pelvic ho ea ho li-ultrasound ho ea ho opereishene ea laparoscopic, mekhoa e sebetsang ka ho fetisisa ea ho fumana endometriosis e na le tšenyo e kholo. Lingaka tse ngata li ka hlahloba endometriosis e ipapisitse le nalane ea bongaka le tlhahlobo ea 'mele. Leha ho le joalo, opereishene ea laparoscopic - e kenyelletsang ho kenya kh'amera e nyane ho hlahloba makhopho a endometrium - e ntse e le mokhoa o khethiloeng oa ho hlahloba.

Endometriosis e ka nka pakeng tsa lilemo tse ka bang 7 ho isa ho tse 10 ho e hlahloba. Ho haella ha liteko tse sa hlaseleng tsa tlhahlobo ea mafu ke le leng la mabaka a entseng nako eo e telele.

Seo se ka fetoha ka letsatsi le leng. Haufinyane, bo-rasaense ba nang le Setsi sa Patlisiso ea Bongaka sa Feinstein ba phatlalalitse phuputso e bonts'ang liteko tsa mehlala ea mali ea ho ilela khoeli li ka fana ka mokhoa o sebetsang, o seng o hlaselang oa ho fumana endometriosis.

Bafuputsi ba fumane hore lisele tse maling a basali ba nang le endometriosis li na le litšobotsi tse itseng. Haholo-holo, mali a ho ilela khoeli a na le lisele tse 'maloa tsa' mele tsa tlhaho tse bolaeang popelo. E ne e boetse e tloaetse ho ba le lisele tsa "stem" tse holofetseng, ts'ebetso e lokisang popelo bakeng sa bokhachane.

Ho hlokahala lipatlisiso tse ling. Empa ho ka etsahala hore li-marker tsena ka letsatsi le leng li ka fana ka tsela e potlakileng le e seng e hlaselang ea ho hlahloba endometriosis.

Lipatlisiso tse ling tsa endometriosis li atametse

Lipatlisiso mabapi le tlhahlobo le kalafo ea endometriosis li ntse li tsoela pele. Liphuputso tse peli tse kholo - le tse ling tsa sci-fi li hlahile qetellong ea 2018:

Lisele tse ikarabellang

Phuputsong e tsoang Northwestern Medicine, bafuputsi ba fumane hore lisele tsa motho tse bakoang ke pluripotent stem (iPS) li ka "etsoa" ho li fetola lisele tsa popelo tse phetseng hantle. Sena se bolela hore lisele tsa popelo tse bakang bohloko kapa ho ruruha li ka nkeloa sebaka ke lisele tse phetseng hantle.

Lisele tsena li entsoe ka phepelo ea mosali ea lisele tsa iPS. Seo se bolela hore ha ho na kotsi ea ho lahloa ke litho, joalo ka ha ho na le mefuta e meng ea ho jala.

Ho hlokahala lipatlisiso tse ling. Empa ho na le monyetla oa hore kalafo e thehiloeng liseleng e be tharollo ea nako e telele ho endometriosis.

Phekolo ea Gene

Lebaka la endometriosis ha le tsejoe. Phuputso e 'ngoe e bontša hore ho hatella liphatsa tsa lefutso tse itseng ho ka nka karolo.

Bo-rasaense ba Yunivesithi ea Yale ba phatlalalitse phuputso e fumaneng hore microRNA Let-7b - selelekela sa lefutso se laolang liphatsa tsa lefutso - e hatelloa ho basali ba nang le endometriosis. Tharollo e bile efe? Ho fana ka Let-7b ho basali ho ka thusa ho alafa boemo bona.

Ho fihlela joale, kalafo e bontšitsoe feela hore e sebetsa ho litoeba. Bafuputsi ba bone liphokotso tse kholo ho liso tsa endometriamo kamora ho enta litoeba ka Let-7b. Lipatlisiso tse ling lia hlokahala pele ho liteko bathong.

Haeba kalafo ea liphatsa tsa lefutso e ipaka e sebetsa bathong, e ka ba mokhoa oa ho phekola endometriosis o sa sebetseng, o sa hlaseleng, hape o seng oa lihormone.

Tsela

Le ha ho se na pheko ea endometriosis, ea phekoleha. Lipatlisiso ka boemo, likhetho tsa kalafo le tsamaiso li ntse li tsoela pele. Haeba u thahasella ho ithuta ho eketsehileng, buisana le ngaka ea hau. Ba ka araba lipotso tsa hau mme ba fana ka maikutlo a lisebelisoa tsa ho tseba haholoanyane.