Ntho e 'ngoe le e 'ngoe eo U Lokelang ho e Tseba ka Ente ea Johnson & Johnson ea COVID-19

Litaba

• Ente ea Johnson & Johnson COVID-19 e sebetsa joang?
• Ente ea Johnson & Johnson COVID-19 e sebetsa hantle hakae?
• Boitsebiso bo matla ba COVID-19 bokuli le lefu
• Mefuta e fapaneng ea COVID-19
• U hloka litekanyetso tse kae tsa ente ea Johnson & Johnson COVID-19?
• Ente ea Johnson & Johnson e ama phetiso ea COVID-19 joang?
• Tlhahlobo bakeng sa

Ka la 26 Hlakola, komiti ea boeletsi ea ente ea FDA e ile ea khetha ka bonngoe ho khothaletsa ente ea Johnson & Johnson ea COVID-19 bakeng sa ts'ebeliso ea tšohanyetso. Seo se bolela hore vaksine - e hlokang tekanyetso e le 'ngoe feela - e ka be e loketse ho sebelisoa US mafelong a Hlakubele, ho latela Setsi sa Patlisiso le Leano la Mafu a tšoaetsanoang (CIDRAP).

Empa, ente ea Johnson & Johnson ea COVID-19 e sebetsa hakae? Hona e bapisoa joang le liente tse ling tsa COVID-19 tse tsoang Pfizer le Moderna? Mona ke seo u hlokang ho se tseba.

Ente ea Johnson & Johnson COVID-19 e sebetsa joang?

Haeba u tloaelane le liente tsa COVID-19 tse entsoeng ke Pfizer le Moderna, mohlomong ua tseba hore ke liente tsa mRNA ka bobeli. Seo se bolela hore ba sebetsa ka ho kh'outa karolo ea protheine ea spike ea SARS-CoV-2 (karolo ea vaerase e itšoarellang liseleng tsa 'mele oa hau) le ho sebelisa likotoana tse kentsoeng ho etsa hore mmele oa hau o itšireletse mafung. Masole a mmele kgahlanong le vaerase. (Bona: Ente ea COVID-19 e Atleha Hakae?)

Ente ea Johnson & Johnson e sebetsa ka mokhoa o fapaneng hanyane. Lebaka le leng, ha se ente ea mRNA. Ke ente ea adenovector, ho bolelang hore e sebelisa vaerase e sa sebetseng (tabeng ena, adenovirus, e bakang sefuba se tloaelehileng) joalo ka vector ho fana ka liprotheine (tabeng ena, protheine ea spike e tsoang ho SARS-CoV-2) eo 'mele oa hau o tla e tlisa. hlokomela e le tšokelo le ho theha masole a 'mele khahlanong le, ho bolela Brittany Busse, MD, motsamaisi oa tsa bongaka mosebetsing WorkCare.

Joale, u kanna oa ipotsa hore na ebe ho kenya "vaerase e sa sebetseng" 'meleng oa hau ho tla u kulisa u sa ikemisetsa, empa e ke ke. "Kokoana-hloko e sa sebetsoeng e ke ke ea ikatisa kapa ea u kulisa," ho bolela Abisola Olulade, M.D., ngaka e netefalitsoeng ea boto ea meriana ea malapa ea Sharp Rees-Stealy Medical Group. Sebakeng seo, adenovirus ho ente ea Johnson & Johnson's COVID-19 e sebetsa feela e le sejari (kapa "vector") ea mofuta oa protheine ea SARS-CoV-2 liseleng tsa hau, e leng se etsang hore lisele li etse likopi tsa mofuta oo, oa hlalosa. Nahana ka liphatsa tsa lefutso tsa protheine e le sehlopha sa litaelo tsa hore na 'mele oa hau o ka loantša SARS-CoV-2 joang, ho eketsa Dr. Olulade. O re: "Liprotheine tsena tse nang le likhahla li ka tsejoa ke sesole sa hau sa 'mele' me sa etsa hore u hlahise li-antibodies tse tla itšireletsa khahlanong le COVID." (FYI: Lefu la feberu le sebetsa ka tsela e ts'oanang.)

Le ha theknoloji ena ea vaksine e fapane le ea Pfizer le Moderna, ha se mohopolo o mocha. Ente ea Oxford le AstraZeneca ea COVID - e amohetsoeng hore e sebelisoe EU le UK ka Pherekhong (FDA hajoale e emetse lintlha tse tsoang tekong ea bongaka ea AstraZeneca pele e nahana ka tumello ea US, New York Times litlaleho) - e sebelisa theknoloji e tšoanang ea adenovirus. Johnson & Johnson ba boetse ba sebelisitse theknoloji ho theha ente ea eona ea Ebola, e bontšitsoeng hore e bolokehile ebile e sebetsa ho hlahisa karabelo ea 'mele ea ho itšireletsa mafung.

Ente ea Johnson & Johnson COVID-19 e sebetsa hantle hakae?

Tekong e kholo ea bongaka ea batho ba ka bang 44,000, vaksine ea Johnson & Johnson ea COVID-19 e bontšitsoe e le liperesente tse 66 tse sebetsang ka botlalo ho thibela ho itekanetse (ho hlalosoa e le ho ba le matšoao a le mong kapa a fetang a COVID-19) ho COVID-19 e matla (e tsebahalang ka ho amoheloa ho ICU, ho hloleha ho phefumoloha, kapa ho hloleha ha setho, har'a lintlha tse ling) matsatsi a 28 kamora ho entoa, ho latela phatlalatso ea boralitaba e tsoang k'hamphaning. (Boitsebiso "bo tla romelloa koranteng e hlahlojoang ke lithaka libekeng tse tlang," ho bolela phatlalatso eo.)

Johnson & Johnson le bona ba ile ba arolelana hore boemo ba eona ba ente ea ts'ireletso khahlano le COVID e matla e ne e le liperesente tsa 72 ho la US, liperesente tsa 66 ho Latin America, le liperesente tsa 57 Afrika Boroa (tseo, ha li kopantsoe hammoho, li u fang sekhahla sa katleho ea 66%) . Haeba lipalo tseo li bonahala li le tlase haholo, ho bohlokoa ho hlokomela hore, ha ho bapisoa, lefu la feberu le sebetsa ka liperesente tse 40 ho isa ho tse 60 ho sireletsa 'mele ho feberu, leha ho le joalo e ntse e bapala karolo e kholo ho fokotseng lipetlele le mafu a amanang le feberu. Ngaka Olulade. (Related: Na Flu Shot e ka U Sireletsa ho Coronavirus?)

Boitsebiso bo matla ba COVID-19 bokuli le lefu

Qalong, sekhahla sa katleho ea ente ea Johnson & Johnson ea liperesente tsa 66 e kanna ea utloahala e le tlase, haholo ha o e bapisa le litheko tse sebetsang ho tloha Moderna (liperesente tsa 94.5 tse sebetsang hantle) le Pfizer ("ho feta 90% e sebetsang," ho latela k'hamphani). Empa haeba u cheka ho teba, data ea Johnson & Johnson etsa bonts'a sephetho se ts'episang haholoanyane, haholo ha ho tluoa maemong a matla ka ho fetisisa a COVID-19.

Ho pholletsa le libaka tsohle, ente e bile 85% e sebetsa hantle ho thibela COVID-19 e matla, ho latela phatlalatso ea Johnson & Johnson. Ebile, k'hamphani e hlokometse hore ente ea eona e bonts'a "ts'ireletso e felletseng khahlano le ho kena sepetlele le lefu le amanang le COVID" matsatsi a 28 kamora ho entoa, "ntle le linyeoe tse tlalehiloeng" tsa ho kena sepetlele kapa lefu le amanang le COVID har'a ba amohetseng ente ea Johnson & Johnson.

Mabapi le litla-morao, Johnson & Johnson ba boletse hore ente ea eona ea COVID "ka kakaretso e mamelletsoe hantle" ho bohle ba nkang karolo tekong. Lintlha tsa pele tsa k'hamphani li fana ka maikutlo a hore vaksine e ka baka "litla-morao tse bobebe ho isa tekanyong tse amanang le liente," ho kenyelletsa mokhathala, hlooho e bohloko, bohloko ba mesifa le bohloko ba sebaka sa ente.

Mefuta e fapaneng ea COVID-19

Ho fapana le lithuto tsa Pfizer le Moderna, teko ea vaksine ea Johnson & Johnson e kenyelletsa sephetho libakeng tse ngata - ho kenyeletsoa le tse sa tsoa bona ho nyoloha ha linyeoe tsa COVID tse bakoang ke mefuta e meng e hlahang ea vaerase. Dr. [Olulade o re: “[Mefuta-futa ena] e kanna eaba e ne e se matla ka nako eo liente tsa pejana li neng li hlahlojoa. Ha e le hantle, joale bafuputsi ba ntse ba sheba hore na ho sebetsa joang kaofela Meento ea COVID-19 e kanna ea sireletsa 'mele mefuteng e fapaneng ea COVID-19. Hajoale, Dr. Busse o re mofuta oa UK "o kanna oa se tšoenyehe ka liente tsa COVID." Leha ho le joalo, oa eketsa, moo ke Khopolo-taba ea hore mefuta e fapaneng ea COVID e tsoang Afrika Boroa le Brazil e ka "fetola tsela eo masole a 'mele a sebelisanang le vaerase ka eona" 'me e ka etsa hore masole a 'mele ao a sirelletsang "a se ke a sebetsa hantle." (E amanang: Hobaneng ha likhohlopo tse ncha tsa COVID-19 li hasana ka potlako?)

Seo se boletse, leha ente e kanna ea se thibele tšoaetso ea COVID-19 ka botlalo, ho bonahala e thusa batho ho qoba vaerase e mpe ka ho fetesisa. Dr. Olulade o re: "Seo se boetse se bolela hore se na le bokhoni ba ho fokotsa mojaro tsamaisong ea rona ea tlhokomelo ea bophelo e imetsoeng le ho re atametsa haufi le lebone leo qetellong ea kotopo."

Dr. Olulade oa eketsa: "Ho bohlokoa hape ho hopola hore kapelenyana moo re ka fumanang batho liente, ke liphetoho tse fokolang tsa vaerase tse lokelang ho fetoha le ho ikatisa." "Ke ka lebaka leo re hlokang ho fumana e mong le e mong [ente] kapele kamoo ho ka khonehang."

U hloka litekanyetso tse kae tsa ente ea Johnson & Johnson COVID-19?

Ntle le katleho ea vaksine ka boeona, litsebi li re ente ea Johnson & Johnson ea COVID le eona ea ts'episa hobane e hloka feela ho thunngoa hanngoe, athe liente tsa Pfizer le Moderna e 'ngoe le e' ngoe e hloka ho thunngoa habeli ho arohantsoe ke libeke tse 'maloa.

Dr. Olulade o re: "Ha e le hantle enoa e ka ba motho ea fetolang papali." "Rea bona hore bakuli ba bang, ka bomalimabe, ha ba khutle bakeng sa tekanyetso ea bona ea bobeli," kahoo mokhoa ona oa ho etsa ntho e le 'ngoe o ka fetolela liente tse ngata ka kakaretso.

Phello e 'ngoe e kholo ho ente ea Johnson & Johnson's COVID? Litekanyetso li bonahala li le bonolo ho li boloka le ho li aba ho feta liente tsa Pfizer le tsa Moderna, ka lebaka la ts'ebeliso ea J&J ea theknoloji ea ente ea adenovector. "Adenovirus [ea ente ea Johnson & Johnson] e theko e tlase ebile ha e bobebe [joalo ka mRNA ea liente tsa Pfizer le Moderna]," eo ea bobeli e hlokang ho bolokoa maemong a batang haholo, ho hlalosa Dr. Busse. "Ente ea Johnson & Johnson e tsitsitse ka sehatsetsing ho fihlela likhoeli tse tharo, e leng se nolofalletsang ho romelloa le ho abela ba e hlokang."

Ente ea Johnson & Johnson e ama phetiso ea COVID-19 joang?

"Ho sa le hoseng haholo ho bolela," ho bolela Prabhjot Singh, MD, Ph.D., moeletsi ea ka sehloohong oa bongaka le saense oa CV19 CheckUp, sesebelisoa sa inthaneteng se thusang ho lekola likotsi tsa hau tsa COVID-19. Seo se ea kaofela ea liente tsa COVID-19 tseo re li boneng ho fihlela joale BTW, eseng Johnson & Johnson feela, ho hlokomela Dr. Singh. O re: "Liphuputso tsa pele li bontša hore kotsi ea phetisetso e lokela ho fokotseha kamora ho entoa, empa karabo e hlakileng e hloka thuto e hlophisitsoeng."

Kaha litlamorao tsa liente phetisong ea COVID li ntse li sa tsejoe, ho bohlokoa haholo ho tsoela pele ho roala limaske le ho boloka hole le batho ba kantle ho ntlo ea hau, ho bolela Dr. Olulade. (Ema, na o lokela ho ikhakanya habeli ho itšireletsa khahlanong le COVID-19?)

Ntlha ea bohlokoa: Kaofela tsa liente tsena ho bonahala li fana ka tšireletso e kholo khahlano le COVID-19, e leng ntle haholo. Ho ntse ho le joalo, “ente ha e fane ka tumello ea ho etsa hore u se ke ua itebela,” ho hlalosa Ngaka Olulade. "Re tlameha ho nahana ntle le boithati ka bophelo bo botle le boiketlo ba ba bang ba e-s'o ente 'me ba kanna ba se na ts'ireletso ho COVID."

Litaba tse paleng ena li nepahetse ho tloha nakong ea khatiso. Ha lintlafatso mabapi le coronavirus COVID-19 li ntse li tsoela pele ho fetoha, ho ka etsahala hore tlhaiso-leseling le likhothaletso tse ling paleng ena li fetohile haesale e phatlalatsoa. Re u khothaletsa ho etela khafetsa ka lisebelisoa tse kang CDC, WHO, le lefapha la hau la bophelo bo botle ba sechaba bakeng sa lintlha le likhothaletso tsa morao-rao.

Tlhahlobo bakeng sa