Herceptin - Pheko ea Kankere ea Lebele

Litaba

• E etselitsoe eng
• Mokhoa oa ho sebelisa
• 1. Kankere ea matsoele
• 2. Kankere ea mala
• Litla-morao tse ka bang teng

Herceptin ke sethethefatsi se ipapisitseng le lithibela-mafu tse monoclonal, tse tsoang laboratoring ea Roche, e sebetsang ka kotloloho seleng ea mofets'e mme e sebetsa hantle khahlano le mefuta e meng ea mofets'e.

Meriana ena e na le theko ea li-reais tse ka bang likete tse 10 'me e fumaneha SUS - Sistema Único de Saúde.

E etselitsoe eng

Herceptin e bontšoa kalafong ea batho ba nang le mofetše oa matsoele, kankere ea pele ea matsoele le mofets'e o tsoetseng pele oa kankere.

Mokhoa oa ho sebelisa

Herceptin e lokela ho tsamaisoa ke setsebi sa tlhokomelo ea bophelo:

1. Kankere ea matsoele

Haeba e sebelisoa beke le beke, tekanyetso ea 'mele ea 4 mg / kg ea boima ba' mele e lokela ho fanoa joalo ka tšelo ea methapo e fetang metsotso e 90. Meriana e latelang ea beke le beke e lokela ho ba 2 mg / kg ea boima ba 'mele, e ka tsamaisoang ka ho tšeloa metsotso e 30.

Haeba e sebelisoa libekeng tse ling le tse ling tse 3, tekanyetso ea pele ea ho kenya ke 8 mg / kg boima ba 'mele, e lateloe ke boima ba' mele ba 6 mg / kg, libeke tse ling le tse ling tse 3, ho tšoaetso e ka bang metsotso e 90. Haeba lethal dose ke mamella hantle, nako ea infusion ka fokotswa ho metsotso e 30.

Meriana ena e ka fanoa hammoho le paclitaxel kapa docetaxel.

2. Kankere ea mala

Moriana ona o lokela ho sebelisoa libeke tse ling le tse ling tse 3 'me lethal dose la pele la tlhaselo ke 8 mg / kg ea boima ba' mele, e lateloe ke 6 mg / kg ea boima ba 'mele, e lokelang ho phetoa libekeng tse ling le tse ling tse 3, ha ho tšeloa mali nako e ka etsang metsotso e 90. Haeba lethal dose ke mamella hantle, nako ea infusion ka fokotswa ho metsotso e 30.

Litla-morao tse ka bang teng

Litla-morao tse atileng haholo tse ka hlahang nakong ea kalafo le Herceptin ke nasopharyngitis, tšoaetso, phokolo ea mali, thrombocytopenia, febrile neutropenia, ho fokotsa palo ea lisele tse tšoeu tsa mali, ho fokotseha kapa ho eketsa boima ba 'mele, ho fokotsa takatso ea lijo, ho hlobaela, ho tsekela, hlooho, paresthesia, hypoesthesia, ho fokotsa tatso , ho tabola, conjunctivitis, lymphedema, ho chaba ho hoholo, phefumoloho e khutšoane, epistaxis, ho khohlela, ho tsoa nko le ho utloa bohloko molomong le pharynx.

Ho phaella moo, letšollo, ho hlatsa, ho nyekeloa ke pelo, bohloko ba mpeng, tshilo ya dijo e fokolang, ho sokela, stomatitis, erythema,lekhopho, ho lahleheloa ke moriri, mathata a lipekere le bohloko ba mesifa.

Ke mang ea sa lokelang ho sebelisa

Pheko ena ha ea lokela ho sebelisoa ho batho ba alejiki ho eng kapa eng ea likarolo tsa lebese, basali ba baimana le ba anyesang.

Meriana ena ha e e-so hlahlojoe bana, bacha, maqheku le batho ba nang le ho holofala ha renal kapa hepatic, mme e lokela ho sebelisoa ka hloko.