Hemoglobin Electrophoresis

Litaba

• Hemoglobin electrophoresis ke eng?
• E sebelisetsoa eng?
• Hobaneng ha ke hloka hemoglobin electrophoresis?
• Ho etsahalang nakong ea hemoglobin electrophoresis?
• Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
• Na ho na le likotsi ho hemoglobin electrophoresis?
• Liphetho li bolelang?
• Na ho na le eng kapa eng eo ke hlokang ho e tseba ka hemoglobin electrophoresis?
• Litšupiso

Hemoglobin electrophoresis ke eng?

Hemoglobin ke protheine e liseleng tsa hao tse khubelu tsa mali tse tsamaisang oksijene matšoafong a hao ho ea 'meleng oohle. Ho na le mefuta e fapaneng ea hemoglobin. Hemoglobin electrophoresis ke teko e lekanyang mefuta e fapaneng ea hemoglobin maling. E boetse e sheba mefuta e sa tloaelehang ea hemoglobin.

Mefuta e tloaelehileng ea hemoglobin e kenyelletsa:

• Hemoglobin (Hgb) A, mofuta o tloaelehileng haholo oa hemoglobin ho batho ba baholo ba phetseng hantle
• Hemoglobin (Hgb) F, hemoglobin ea lesea. Mofuta ona oa hemoglobin o fumanoa maseeng a e-so hlahe le masea a sa tsoa tsoaloa. HgbF e nkeloa sebaka ke HgbA nakoana kamora ho hlaha.

Haeba maemo a HgbA kapa HgbF a phahame haholo kapa a le tlase haholo, e ka bonts'a mefuta e meng ea phokolo ea mali.

Mefuta e sa tloaelehang ea hemoglobin e kenyelletsa:

• Hemoglobin (Hgb) S. Mofuta ona oa hemoglobin o fumanoa lefung la sickle cell. Boloetse ba seleng bo kulang ke bokuli bo futsitsoeng bo etsang hore 'mele o etse lisele tse khubelu tsa mali tse bopehileng joaloka sekele. Lisele tse khubelu tsa mali tse phetseng hantle lia fetoha hore li tsebe ho tsamaea habonolo ka methapo ea mali. Lisele tse kulang li ka tšoarella methapong ea mali, tsa baka bohloko bo boholo le bo sa foleng, tšoaetso le mathata a mang.
• Hemoglobin (Hgb) C. Mofuta ona oa hemoglobin ha o tsamaise oksijene hantle. E ka baka mofuta o bobebe oa phokolo ea mali.
• Hemoglobin (Hgb) E. Mofuta ona oa hemoglobin o fumanoa haholo bathong ba litloholo tsa Asia Boroa-bochabela. Batho ba nang le HgbE hangata ha ba na matšoao kapa matšoao a bonolo a phokolo ea mali.

Teko ea hemoglobin electrophoresis e sebelisa motlakase ho sampole ea mali. Sena se arola mefuta e tloaelehileng le e sa tloaelehang ea hemoglobin. Mofuta o mong le o mong oa hemoglobin o ka lekanyetsoa ka bonngoe.

Mabitso a mang: Hb electrophoresis, tlhahlobo ea hemoglobin, tlhahlobo ea hemoglobinopathy, hemoglobin fractionation, Hb ELP, skrine ea sekele ea sekele

E sebelisetsoa eng?

Hemoglobin electrophoresis e lekanya maemo a hemoglobin mme e sheba mefuta e sa tloaelehang ea hemoglobin. E sebelisoa khafetsa ho thusa ho fumana phokolo ea mali, lefu la seleng ea maloetse le mafu a mang a hemoglobin.

Hobaneng ha ke hloka hemoglobin electrophoresis?

U kanna ua hloka ho hlahlojoa haeba u na le matšoao a lefu la hemoglobin. Tsena li kenyelletsa:

• Mokhathala
• Letlalo le putswa
• Jaundice, boemo bo etsang hore letlalo le mahlo a hao a be bosehla
• Bohloko bo boholo (lefu la sekele ea sekele)
• Mathata a kholo (ho bana)

Haeba u sa tsoa ba le ngoana, ngoana oa hau ea sa tsoa tsoaloa o tla hlahlojoa e le karolo ea tlhahlobo ea lesea le sa tsoa tsoaloa. Ho hlahloba masea a sa tsoa tsoaloa ke sehlopha sa liteko tse fuoang masea a mangata a Amerika nakoana kamora ho hlaha. Ho hlahloba ho hlahloba maemo a fapaneng. Bongata ba maemo ana a ka phekoloa ha a ka fumanoa kapele.

U ka 'na ua batla ho hlahlojoa haeba u le kotsing ea ho ba le ngoana ea nang le lefu la sele ea kankere kapa lefu le leng le futsitsoeng la hemoglobin. Mabaka a kotsi a kenyelletsa:

• Nalane ea lelapa
• Semelo sa morabe
  • United States, batho ba bangata ba nang le maloetse a likokoana-hloko ke litloholo tsa Maafrika.
  • Thalassemia, lefu le leng le futsitsoeng la hemoglobin, le atile haholo bathong ba Italy, Greek, Middle East, Asia Boroa le Afrika.

Ho etsahalang nakong ea hemoglobin electrophoresis?

Ngaka ea tlhokomelo ea bophelo e tla nka sampole ea mali mothapong o letsohong la hao, e sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

Ho leka lesea le sa tsoa tsoaloa, mofani oa tlhokomelo ea bophelo o tla hloekisa serethe sa ngoana oa hau ka joala ebe o phunya serethe ka nale e nyane. Mofani oa thepa o tla bokella marotholi a 'maloa a mali ebe o beha bandage setšeng.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ha o hloke litokisetso tse khethehileng bakeng sa tlhahlobo ea hemoglobin electrophoresis.

Na ho na le likotsi ho hemoglobin electrophoresis?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.

Lesea la hau le ka 'na la ikutloa le phunya hanyane ha serethe se ts'oaroa,' me ho ka hlaha leqeba le lenyane setšeng. Sena se lokela ho tloha kapele.

Liphetho li bolelang?

Liphetho tsa hau li tla bontša mefuta ea hemoglobin e fumanoeng le maemo a e ngoe le e ngoe.

Litekanyetso tsa hemoglobin tse phahameng haholo kapa tse tlase haholo li ka bolela:

• Thalassemia, boemo bo amang tlhahiso ea hemoglobin. Matšoao a tloha ho bonolo ho isa ho a matla.
• Tšobotsi ea lisele tse kulang. Boemong bona, o na le lefutso le le leng la sekele le lefutso le le leng le tloaelehileng. Batho ba bangata ba nang le semelo sa sele ea sekele ha ba na mathata a bophelo bo botle.
• Boloetse ba sele
• Boloetse ba Hemoglobin C, boemo bo bakang mofuta o fokolang oa phokolo ea mali 'me ka linako tse ling boea bo atolohileng le bohloko bo kopaneng
• Boloetse ba Hemoglobin SC, boemo bo bakang mofuta o bobebe kapa o itekanetseng oa lefu la sele ea sekele

Liphetho tsa hau li kanna tsa bonts'a hore na bothata bo itseng bo bobebe, bo itekanetse kapa bo matla.

Liphetho tsa liteko tsa Hemoglobin electrophoresis hangata li bapisoa le liteko tse ling, ho kenyeletsoa palo e felletseng ea mali le smear ea mali. Haeba u na le lipotso mabapi le liphetho tsa hau, bua le mofani oa tlhokomelo ea bophelo.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Na ho na le eng kapa eng eo ke hlokang ho e tseba ka hemoglobin electrophoresis?

Haeba u le kotsing ea ho ba le ngoana ea nang le lefu la hemoglobin, u ka batla ho bua le moeletsi oa liphatsa tsa lefutso. Moeletsi oa liphatsa tsa lefutso ke setsebi se koetlisitsoeng ka ho khetheha liphatseng tsa lefutso le liteko tsa lefutso. A ka u thusa ho utloisisa bothata le kotsi ea ho bo fetisetsa ho ngoana oa hau.

Litšupiso

1. Mokhatlo oa Amerika oa Hematology [Marang-rang]. Washington DC: Mokhatlo oa Amerika oa Hematology; c2020. Boloetse ba Sickle Cell; [ho qotsitsoe ka la 2020 Pherekhong 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.hematology.org/Patients/Anemia/Sickle-Cell.aspx
2. Kliniki ea Cleveland [Inthanete]. Cleveland (OH): Kliniki ea Cleveland; c2020. Sickle Cell Anemia: Kakaretso; [ho qotsitsoe ka la 2020 Pherekhong 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://my.clevelandclinic.org/health/diseases/4579-sickle-cell-anemia
3. Bophelo ba Bana ho tsoa Nemours [Marang-rang]. Jacksonville (FL): Motheo oa Nemours; c1995-2020. Teko ea Mali: Hemoglobin Electrophoresis; [e qotsitsoeng ka la 2020 Pherekhong 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://kidshealth.org/en/parents/test-electrophoresis.html
4. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001--2020. Tlhatlhobo ea hemoglobinopathy; [e ntlafalitsoeng 2019 Sep 23; e qotsitsoeng ka 2020 Jan 10]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/hemoglobinopathy-evaluation
5. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001--2020. Jaundice; [e ntlafalitsoeng 2019 Oct 30; e qotsitsoeng ka 2020 Jan 10]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/conditions/jaundice
6. Tlhakubele ea Dimes [Marang-rang]. Arlington (VA): Hlakubele ea Dimes; c2020. Litlhahlobo tsa masea a sa tsoa tsoaloa tsa ho hlahloba ngoana oa hau; [e qotsitsoeng ka la 2020 Pherekhong 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.marchofdimes.org/baby/newborn-screening-tests-for-your-baby.aspx
7. Phetolelo ea Merck Manual Consumer [Inthanete]. Kenilworth (NJ): Merck & Co Inc .; 2020. Hemoglobin C, SC, le Mafu a E; [e ntlafalitsoeng 2019 Feb; e qotsitsoeng ka 2020 Jan 10]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.merckmanuals.com/home/blood-disorders/anemia/hemoglobin-c,-s-c,-and-e-diseases?query=hemoglobin%20electrophoresis
8. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liteko tsa Mali; [ho qotsitsoe ka la 2020 Pherekhong 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
9. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Boloetse ba Sickle Cell; [e qotsitsoeng ka la 2020 Pherekhong 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/sickle-cell-disease
10. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Thalassemias; [ho qotsitsoe ka la 2020 Pherekhong 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/thalassemias
11. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Gainesville (FL): Univesithi ea Florida Health; c2020. Hemoglobin electrophoresis: Kakaretso; [e ntlafalitsoeng 2020 Jan 10; e qotsitsoeng ka 2020 Jan 10]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/hemoglobin-electrophoresis
12. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2020. Tlhahisoleseling ea Bophelo: Hemoglobin Electrophoresis: Liphetho; [e ntlafalitsoeng 2019 Mar 28; e qotsitsoeng ka 2020 Jan 10]; [li-skrini tse ka bang 8]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html#hw39128
13. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2020. Tlhahisoleseling ea Bophelo: Hemoglobin Electrophoresis: Tlhatlhobo ea Teko; [e ntlafalitsoeng 2019 Mar 28; e qotsitsoeng ka 2020 Jan 10]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html
14. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2020. Tlhahisoleseling ea Bophelo: Hemoglobin Electrophoresis: Seo U ka Nahanang ka Sona; [e ntlafalitsoeng 2019 Mar 28; e qotsitsoeng ka 2020 Jan 10]; [likhalase tse ka bang 10]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html#hw39144
15. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2020. Tlhahisoleseling ea Bophelo: Hemoglobin Electrophoresis: Hobaneng ha e etsoa; [e ntlafalitsoeng 2019 Mar 28; e qotsitsoeng ka 2020 Jan 10]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html#hw39110

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.