Sengoli: Randy Alexander
Letsatsi La Creation: 24 April 2021
Ntlafatsa Letsatsi: 1 November 2024
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Ant-inflammatory groups in 2 minutes: NSAIDs, Glucocorticoid, Zileuton, Zafirlukast and Montelukast
Video: Ant-inflammatory groups in 2 minutes: NSAIDs, Glucocorticoid, Zileuton, Zafirlukast and Montelukast

Litaba

Kakaretso

Mathata a mangata a bophelo bo botle a kenyelletsa ho ruruha. Li-glucocorticoids li sebetsa hantle ho emeng ho ruruha ho kotsi ho bakoang ke mathata a mangata a sesole sa 'mele. Litlhare tsena li na le ts'ebeliso tse ling tse ngata. Leha ho le joalo, li tla le litla-morao. Tsena li ka ba matla, haholo haeba o sebelisa lithethefatsi tsena nako e telele haholo.

Li-glucocorticoids ke eng?

Lithethefatsi tsa glucocorticoid ke mefuta e entsoeng ke batho ea li-glucocorticoids, li-steroid tse hlahang ka tlhaho 'meleng oa hau. Li na le mesebetsi e mengata. E 'ngoe ke ho sitisa ho ruruha ka ho kenella liseleng le ho hatella liprotheine tse tsoelang pele ho khothaletsa ho ruruha. Li boetse li thusa 'mele oa hau ho sebetsana le khatello ea maikutlo le ho laola hore na' mele oa hau o sebelisa mafura le tsoekere joang.

Hobane li-glucocorticoids li na le mesebetsi e mengata haholo, li-glucocorticoids tse entsoeng ke batho kapa tsa maiketsetso li se li entsoe ho thusa ho sebetsana le maemo a fapaneng.

Lethathamo la lithethefatsi tsa glucocorticoid

Mehlala ea lithethefatsi tsa glucocorticoid e kenyelletsa:

  • beclomethasone
  • betamethasone
  • budesonide
  • cortisone
  • dexamethasone
  • hydrocortisone
  • methylprednisolone
  • sebeletso
  • prednisone
  • selebella

Seo glucocorticoids se phekola

Synthetic glucocorticoids e ka ba matla haholo ho feta li-steroid tsa tlhaho. Li sebelisetsoa ho alafa maemo a mangata.


Mathata a ho itšireletsa mafung

Ho itšireletsa mafung ho ka baka tšenyo e kholo ha motho a hlasela ka phoso. Ho itšireletsa mafung ho kenyelletsa:

  • lefu la sclerosis
  • ramatiki ea ramatiki
  • lefu la ho ruruha mala
  • ulcerative colitis
  • psoriasis
  • eczema

Li-glucocorticoids li ka fokotsa hore na lisele tse itšireletsang mafung li sebetsa joang. Sena se thusa ho fokotsa tšenyo e ka hare ea mafu ana. Li hatella ho ruruha ho tsoa likarabong tse ikemetseng. Sena se ka fokotsa bohloko, ho ruruha, ho peperana le ho hlohlona.

Matšoafo le asthma

Matšoafo le asma ke maemo ao sesole sa hau sa 'mele se arabelang linthong tse seng kotsi hangata. Maemong ana, lintho tse kang peo e phofo kapa linate li ka baka tšusumetso e matla ea ho ruruha. Matšoao a ka fapana mme a kenyelletsa:

  • ho hlohlona
  • ho hlohlona, ​​mahlo a metsi
  • hlooho e bobebe
  • bofubelu, hives kapa lekhopho
  • ho thimola le ho petetsane kapa ho tsoa nko
  • ho ruruha ha sefahleho, molomo, kapa mmetso
  • ho hema ka thata

Li-glucocorticoids li ka sebetsana le khatello ena e matla ka ho emisa ho ruruha le ho khutsisa ts'ebetso ea lisele tsa 'mele.


Ho se lekane ha Adrenal

Haeba u na le khaello ea adrenal, 'mele oa hau o ke ke oa hlahisa cortisol e lekaneng. Sena se ka bakoa ke boemo bo kang lefu la Addison kapa ho tlosoa ha litšoelesa tsa hau tsa adrenal. Li-glucocorticoids li ka sebelisoa ho nkela cortisol sebaka seo 'mele oa hau o ke keng oa hlola o khona ho se etsa.

Ho hloleha ha pelo

Tšebeliso ea nako e khuts'oane (e ka tlase ho matsatsi a 7) ea li-glucocorticoids e ka thusa ho phekola ho hloleha ha pelo ka ho eketsa bokhoni ba 'mele oa hau ho arabela ho diuretics e itseng. Leha ho le joalo, sena ha se tšebeliso e tloaelehileng.

Kankere

Li-glucocorticoids li ka sebelisoa kalafong ea mofets'e ho fokotsa tse ling tsa litla-morao tsa chemotherapy. Li kanna tsa sebelisoa ho bolaea lisele tse ling tsa mofets'e ho mofets'e o mong, ho kenyelletsa:

  • a hlobaetsang lymphoblastic kankere ea mali
  • a sa foleng a lymphoblastic leukemia
  • Hodgkin lymphoma
  • E seng Hodgkin lymphoma
  • mefuta e mengata ea myeloma

Maemo a letlalo

Maemo a letlalo ho tloha ho eczema ho isa ho chefo ivy a phekoloa ka glucocorticoids. Tsena li kenyelletsa litlolo tsa ka holimo tsa thekiso le lengolo la ngaka tseo u li sebelisang letlalong la hao le meriana eo u e sebelisang ka molomo.


Phekolo

Li-glucocorticoids li ka sebelisoa nakong ea li-neurosurgeries tse thata. Li fokotsa ho ruruha linthong tse thata. Li fuoa hape hang kamora ho kenella ha setho ho thusa ho thibela sesole sa 'mele ho hana setho sa mofani.

Litla-morao

Li-glucocorticoids li ka utloahala joalo ka lithethefatsi tsa mohlolo, empa li na le litla-morao. Tse ling tsa litla-morao li ka ba kotsi haholo. Ke kahoo lithethefatsi tsena li sa laeloang tšebeliso ea nako e telele.

Lithethefatsi tsena li ka:

  • eketsa tsoekere ea mali, e ka bakang lefu la tsoekere la nakoana le mohlomong
  • hatella bokhoni ba 'mele oa hau ba ho monya calcium, bo ka lebisang ho masapo
  • eketsa li-cholesterol tsa hau le li-triglyceride
  • eketsa kotsi ea liso le gastritis
  • lieha ho fola ha leqeba, le hlokang ho ruruha ho itseng
  • hatella sesole sa hau sa 'mele' me se u nolofalletse ho tšoaetsoa habonolo

Tšebeliso ea nako e telele ea li-glucocorticoids e ka baka tahlehelo ea lisele tsa mesifa. E ka boela ea fella ka Cushing's syndrome, e ka lebisang ho:

  • nko e mafura pakeng tsa mahetla a hao
  • sefahleho se chitja
  • boima ba 'mele
  • matšoao a otlolohileng a pinki
  • masapo a fokolang
  • lefu la tsoekere
  • khatello e phahameng ea mali
  • letlalo le lesesane
  • ho fola butle
  • makhopho
  • linako tse sa tloaelehang tsa ho ilela khoeli
  • fokotseha libido
  • mokgathala
  • ho tepella maikutlo

Haeba u sebelisitse li-glucocorticoids nako e fetang libeke tse 'maloa, ngaka ea hau e kanna ea theola litekanyetso tsa hau butle ho fapana le hore o khaotse ho li nka hang-hang. Sena se thusa ho thibela litlamorao tsa ho hula. 'Mele oa hau ka tlhaho o etsa li-glucocorticoids, empa ha o qala ho li noa e le meriana,' mele oa hau o itšoara ka ho o fokotsa o le mong. Ha o emisa ho noa li-glucocorticoids, 'mele oa hau o hloka nako ho qala ho iketsetsa maemo a tloaelehileng hape.

Bua le ngaka ea hau

Li-glucocorticoids e ka ba lithethefatsi tse sebetsang bakeng sa kalafo tse fapaneng. Leha ho le joalo, ho bohlokoa ho leka-lekanya tlhoko ea kalafo ea glucocorticoid khahlano le litla-morao. Haeba ngaka ea hau eu fa kalafo ea glucocorticoid, ba bolelle ka litla-morao tseo u nang le tsona. Hape ke habohlokoa ho noa lithethefatsi hantle feela joalokaha ho laetsoe, ho kenyeletsoa le ha u li emisa. Ngaka ea hau e ka u tlosa meriana ea hau butle ho thibela ho tsoa.

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