Claw ea Diabolose: Melemo, Litla-morao le Tekanyo

Litaba

• Claw ea Diabolose ke Eng?
• E ka Fokotsa Ho Ruruha
• E ka Ntlafatsa Osteoarthritis
• E ka Fokotsa Matšoao a Gout
• E ka Fokotsa Bohloko bo Khutlelang
• E kanna ea Khothaletsa ho Theola Boima ba 'mele
• Litla-morao le Likamano
• Litekanyo tse khothalletsoang
• Ntlha ea Bohlokoa

Claw ea Devil, e tsejoang ka mahlale e le Harpagophytum e hlahisa, ke semela se tsoaletsoeng Afrika Boroa. E na le lebitso la eona le tšabehang ka litholoana tsa eona, tse behang likhakanyo tse nyane tse kang lihakisi.

Ka tloaelo, metso ea semela sena e sebeliselitsoe ho phekola maloetse a fapaneng, joalo ka feberu, bohloko, ramatiki le ho se je lijo ka maleng (1).

Sengoliloeng sena se hlahloba melemo e ka bang teng ea claw ea diabolose.

Claw ea Diabolose ke Eng?

Claw ea Devil ke semela se thunyang sa lelapa la sesame. Metso ea sona e paka metsoako e mengata e sebetsang ea semela mme e sebelisoa e le tlatsetso ea litlama.

Haholo-holo, claw ea diabolose e na le iridoid glycosides, sehlopha sa metsoako se bonts'itseng litlamorao tse khahlano le ho ruruha ().

Liphuputso tse ling empa eseng kaofela li fana ka maikutlo a hore iridoid glycosides le eona e ka ba le litlamorao tsa antioxidant. Sena se bolela hore semela se ka ba le bokhoni ba ho qoba litlamorao tse senyang tsa sele tsa limolek'hule tse sa tsitsang tse bitsoang li-radical tse sa lefelloeng (3,,).

Ka mabaka ana, li-supplement tsa diabolose tsa claw li ithutiloe e le pheko e ka bang teng bakeng sa maemo a amanang le ho ruruha, joalo ka ramatiki le gout. Ntle le moo, ho entsoe tlhahiso ea ho fokotsa bohloko mme e ka ts'ehetsa ho theola boima ba 'mele.

U ka fumana li-supplement tsa claw tsa diabolose ka mokhoa oa li-extracts le li-capsules tse tsepamisitsoeng, kapa u silafalitsoe hore e be phofo e ntle. E boetse e sebelisoa e le motsoako oa li-tea tse fapaneng tsa litlama.

Claw ea Diabolose ke setlama sa litlama se sebelisoang haholo-holo e le kalafo e 'ngoe bakeng sa ramatiki le bohloko. E hlaha ka mefuta e mengata, ho kenyeletsoa likaroloana tse tsepamisitsoeng, li-capsules, powders le li-tea tsa litlama.

E ka Fokotsa Ho Ruruha

Ho ruruha ke karabelo ea tlhaho ea 'mele oa hau ho tsoa likotsi le tšoaetso. Ha u itšeha monoana, u khumama ka lengole kapa u theoha ke feberu, 'mele oa hau o arabela ka ho etsa hore sesole sa hau sa' mele se sebetse ().

Le ha ho ruruha ho hong ho hlokahala ho sireletsa 'mele oa hau khahlanong le kotsi, ho ruruha ho sa foleng ho ka ba kotsi bophelong. Ebile, lipatlisiso tse tsoelang pele li hokahantse ho ruruha ho sa foleng le lefu la pelo, lefu la tsoekere le mathata a boko (,,).

Ho joalo, ho boetse ho na le maemo a khetholloang ka kotloloho ke ho ruruha, joalo ka lefu la ho ruruha hoa mala (IBD), ramatiki le gout (, 11,).

Claw ea Diabolose e hlahisitsoe e le pheko e ka bang teng ea maemo a ho ruruha hobane e na le metsoako ea limela e bitsoang iridoid glycosides, haholo-holo harpagoside. Lithutong tsa li-tube le tsa liphoofolo, harpagoside e thibetse likarabo tsa ho ruruha ().

Mohlala, phuputso ea litoeba e bontšitse hore harpagoside e hatelletse haholo ts'ebetso ea li-cytokines, e leng limolek'hule 'meleng oa hau tse tsejoang ho khothaletsa ho ruruha ().

Leha claw ea diabolose e sa ka ea ithutoa haholo bathong, bopaki ba pele bo fana ka maikutlo a hore e kanna ea ba kalafo e 'ngoe bakeng sa maemo a ho ruruha.

Claw ea Diabolose e na le metsoako ea limela e bitsoang iridoid glycosides, e bonts'itsoeng ho hatella ho ruruha lithutong tsa liteko le lithuto tsa liphoofolo.

E ka Ntlafatsa Osteoarthritis

Osteoarthritis ke mofuta o atileng ka ho fetisisa oa ramatiki, o amang batho ba baholo ba fetang limilione tse 30 US ().

E etsahala ha sekoaelo se sireletsang lipheletsong tsa masapo a kopaneng - se bitsoang lefufuru - se fela. Sena se etsa hore masapo a kopane hammoho, ho felle ka ho ruruha, ho satalla le bohloko (16).

Ho hlokahala lithuto tse ling tsa boleng bo holimo, empa lipatlisiso tsa hajoale li bontša hore claw ea diabolose e ka sebetsa hantle ho fokotsa bohloko bo amanang le lefu la masapo a mabeli.

Mohlala, phuputso e 'ngoe ea bongaka e amang batho ba 122 ba nang le lefu la masapo le manonyeletso lengoleng le lethekeng e bontšitse hore 2,610 mg ea claw ea diabolose letsatsi le letsatsi e ka sebetsa hantle ho fokotsa bohloko ba lefu la masapo joalo ka diacerein, meriana e atisang ho sebelisoa ho alafa boemo bona ().

Ka mokhoa o ts'oanang, phuputso ea likhoeli tse 2 ho batho ba 42 ba nang le lefu la masapo a sa foleng la osteoarthritis e fumane hore ho tlatselletsa letsatsi le leng le le leng ka claw ea diabolose hammoho le turmeric le bromelain, eo ho nahanoang hore e na le litlamorao tse khahlanong le ho ruruha hape, e fokolitse bohloko ka karolelano ea 46% ().

Phuputso e fana ka maikutlo a hore claw ea diabolose e ka thusa ho kokobetsa bohloko ba manonyeletso bo amanang le lefu la masapo mme e ka sebetsa hantle joalo ka setlhare se kokobetsang bohloko sa diacerein.

E ka Fokotsa Matšoao a Gout

Gout ke mofuta o mong o tloaelehileng oa ramatiki, o khetholloang ka ho ruruha ho bohloko le bofubelu manonyeletso, hangata menoaneng, maqaqailaneng le mangoleng ().

E bakoa ke bongata ba asiti ea uric e maling, e thehoang ha purine - metsoako e fumanoang lijong tse ling - e senyeha ().

Meriana, joalo ka li-anti-inflammatory drug (NSAIDs), hangata li sebelisoa ho fokotsa bohloko le ho ruruha ho bakoang ke gout.

Ka lebaka la litlamorao tsa eona tse khahlanong le ho ruruha le monyetla oa ho fokotsa bohloko, claw ea diabolose e hlahisitsoe e le kalafo e 'ngoe bakeng sa ba nang le gout (20).

Hape, bafuputsi ba bang ba re e ka fokotsa uric acid, leha bopaki ba mahlale bo lekantsoe. Phuputsong e 'ngoe, litekanyo tse phahameng tsa claw ea diabolose li fokolitse litekanyetso tsa uric acid ho litoeba (21, 22).

Le ha lipatlisiso tsa "tube-test" le "liphoofolo" li bonts'a hore claw ea diabolose e ka hatella ho ruruha, lithuto tsa bongaka tse tšehetsang ts'ebeliso ea eona bakeng sa gout ha li fumanehe.

Ho ipapisitsoe le lipatlisiso tse lekanyelitsoeng, claw ea diabolose e hlahisitsoe ho fokotsa matšoao a gout ka lebaka la litlamorao tsa eona tse khahlano le ho ruruha le monyetla oa ho fokotsa maemo a asiti ea uric.

E ka Fokotsa Bohloko bo Khutlelang

Mahlaba a morao a morao ke moroalo ho ba bangata. Ebile, ho hakanngoa hore batho ba baholo ba 80% ba e fumana ka nako e 'ngoe kapa e' ngoe (23).

Hammoho le litlamorao tse khahlano le ho ruruha, claw ea diabolose e bonts'a bokhoni ba ho kokobetsa bohloko, haholoholo mahlaba a tlase a morao. Bafuputsi ba bolela hore sena ke harpagoside, motsoako o sebetsang oa semela se lenaneng la diabolose.

Phuputsong e 'ngoe, ho ntšoa ha harpagoside ho bonahala ho sebetsa ka mokhoa o ts'oanang joalo ka setlhare se khahlanong le ho ruruha sa nonsteroidal (NSAID) se bitsoang Vioxx. Kamora libeke tse 6, bohloko ba mokokotlo ba litho tsa sehlopha bo ile ba fokotsoa ka liperesente tse 23% ka harpagoside le 26% le NSAID ().

Hape, lithuto tse peli tsa kliniki li fumane hore ligrama tsa 50-100 tsa harpagoside ka letsatsi li ne li sebetsa hantle ho fokotsa bohloko ba morao bo tlase ha bo bapisoa le kalafo, empa lithuto tse ling lia hlokahala ho netefatsa liphetho tsena (,).

Claw ea Diabolose e bonts'a bokhoni ba ho kokobetsa bohloko, haholoholo bakeng sa mahlaba a tlase a mokokotlo. Bafuputsi ba re sena se entsoe ka motsoako oa semela o lenakeng la diabolose o bitsoang harpagoside. Leha ho le joalo, lipatlisiso tse ling lia hlokahala ho netefatsa litlamorao tsena.

E kanna ea Khothaletsa ho Theola Boima ba 'mele

Ntle le ho fokotsa bohloko le ho ruruha, claw ea diabolose e ka thibela takatso ea lijo ka ho sebelisana le hormone ea tlala ghrelin ().

Ghrelin e patiloe ke mpa ea hau. O mong oa mesebetsi ea ona ea mantlha ke ho bontša boko ba hau hore ke nako ea ho ja ka ho eketsa takatso ea lijo ().

Phuputsong ea litoeba, liphoofolo tse amohetseng phofo ea motso oa diabolose li jele lijo tse fokolang haholo lihoreng tse 'ne tse latelang ho feta tse phekotsoeng ka placebo ().

Leha liphetho tsena li khahla, litlamorao tsena tsa ho fokotsa takatso ea lijo ha li e-so ithutoe bathong. Ka hona, bopaki bo matla bo tšehetsang ho sebelisa claw ea diabolose bakeng sa ho theola boima ba 'mele ha bo fumanehe ka nako ena.

Claw ea Diabolose e kanna ea hatella ketso ea ghrelin, hormone 'meleng oa hau e eketsang takatso ea lijo le ho supa boko ba hau hore ke nako ea ho ja. Leha ho le joalo, lipatlisiso tse entsoeng ke batho ka taba ena ha li fumanehe.

Litla-morao le Likamano

Claw ea Diabolose e bonahala e bolokehile ha e nooa ka litekanyetso ho fihlela ho 2,610 mg letsatsi le leng le le leng, leha litlamorao tsa nako e telele li sa batlisisoa (29).

Litla-morao tse tlalehiloeng li bobebe, 'me se atileng haholo ke letšollo. Litlamorao tse bohloko li kenyelletsa khatello ea mmele, hlooho le ho khohlela ().

Leha ho le joalo, maemo a mang a ka u beha kotsing e kholo ea liphetoho tse tebileng (31):

• Mathata a pelo: Boithuto bo bontšitse hore claw ea diabolose e ka ama ho otla ha pelo, ho otla ha pelo le khatello ea mali.
• Lefu la tsoekere: Claw ea Diabolose e ka fokotsa maemo a tsoekere maling le ho matlafatsa litlamorao tsa meriana ea lefu la tsoekere.
• Majoe a majoe: Ts'ebeliso ea claw ea diabolose e kanna ea eketsa sebopeho sa bile mme ea mpefatsa mathata ho ba nang le gallstones.
• Liso tsa ka maleng: Tlhahiso ea asiti ka mpeng e ka eketseha ka ts'ebeliso ea claw ea diabolose, e ka mpefatsang liso tsa peptic.

Meriana e tloaelehileng e kanna ea sebelisana hampe le claw ea diabolose, ho kenyeletsoa le li-anti-inflammatory drug (NSAIDs) tsa ngaka, li-thinner tsa mali le li-reducer tsa mpa (31):

• Li-NSAID: Claw ea Diabolose e ka liehisa ho kenella ha li-NSAID tse tsebahalang, joalo ka Motrin, Celebrex, Feldene le Voltaren.
• Li-thinner tsa mali: Claw ea Diabolose e ka ntlafatsa litlamorao tsa Coumadin (eo hape e tsejoang ka hore ke warfarin), e ka lebisang ho eketseheng ho tsoa mali le matetetso.
• Lisebelisoa tsa asiti tsa mala: Claw ea Diabolose e ka fokotsa litlamorao tsa li-acid tse fokotsang mpa, tse kang Pepcid, Prilosec le Prevacid.

Lena ha se lenane le akaretsang la litšebelisano tsa meriana. E le hore u be lehlakoreng le sireletsehileng, lula u buisana le ngaka ea hau ka tšebeliso ea litlatsetso.

Bakeng sa batho ba bangata, kotsi ea litla-morao bakeng sa claw ea diabolose e tlase. Leha ho le joalo, e kanna ea se tšoanele batho ba nang le maemo a itseng a bophelo bo botle le ba noang meriana e itseng.

Litekanyo tse khothalletsoang

Claw ea Diabolose e ka fumanoa e le sehlahisoa se kopantsoeng, capsule, letlapa kapa phofo. E boetse e sebelisoa e le motsoako oa li-tea tsa litlama.

Ha u khetha tlatsetso, batla mohopolo oa harpagoside, e leng motsoako o sebetsang ho claw ea diabolose.

Litekanyo tsa 600-260 mg, ea claw ea diabolose letsatsi le letsatsi li sebelisitsoe liphuputsong tsa lefu la masapo le bohloko ba mokokotlo. Ho ipapisitse le mohopolo o ntšitsoeng, hona ho tšoana hantle le 50-100 mg ea harpagoside ka letsatsi (,,,).

Ntle le moo, tlatsetso e bitsoang AINAT e sebelisitsoe e le pheko ea lefu la masapo. AINAT e na le 300 mg ea claw ea diabolose, hammoho le 200 mg ea turmeric le 150 mg ea bromelain - lihlahisoa tse ling tse peli tsa semela tse lumeloang hore li na le litlamorao tse khahlano le ho ruruha ().

Bakeng sa maemo a mang, lithuto tse lekaneng tsa ho fumana litekanyetso tse sebetsang ha li fumanehe.Ho feta moo, claw ea diabolose e sebelisitsoe feela ho fihlela selemo se le seng lithutong. Leha ho le joalo, claw ea diabolose e bonahala e sireletsehile ho batho ba bangata ka tekanyetso ho fihlela ho 2,610 mg ka letsatsi (29).

Hopola hore maemo a mang, joalo ka lefu la pelo, lefu la tsoekere, majoe a liphio le liso tsa ka mpeng, a ka eketsa menyetla ea hau ea litlamorao ha o nka claw ea diabolose.

Hape, tekanyo efe kapa efe ea claw ea diabolose e ka kena-kenana le meriana eo u ka 'nang ua e noa. Sena se kenyelletsa lithethefatsi tse seng khahlanong le ho ruruha (li-NSAID), tse fokotsang mali le tse fokotsang asiti ea mala.

Claw ea Diabolose e bonahala e le molemo ka tekanyetso ea 600-2610 mg ka letsatsi. Ho hlokahala lithuto tse ling ho fumana hore na litekanyetso tsena li sebetsa hantle ebile li bolokehile nako e telele.

Ntlha ea Bohlokoa

Claw ea Diabolose e ka imolla bohloko bo bakoang ke maemo a ho ruruha joalo ka ramatiki mme e kanna ea hatella lihormone tsa tlala.

Litekanyetso tsa letsatsi le letsatsi tsa 600-2,610 mg li bonahala li sireletsehile, empa ha ho na khothatso ea semmuso e teng.

Litla-morao ka kakaretso li bobebe, empa claw ea diabolose e ka mpefatsa litaba tse ling tsa bophelo bo botle mme ea sebelisana le meriana e itseng.

Joalo ka li-supplements tsohle, claw ea diabolose e lokela ho sebelisoa ka hloko. Etsa bonnete ba hore o bua le ngaka ea hau pele o e noa.