Bopa Kinase

Litaba

• Teko ea creatine kinase (CK) ke eng?
• E sebelisetsoa eng?
• Hobaneng ha ke hloka tlhahlobo ea CK?
• Ho etsahalang nakong ea tlhahlobo ea CK?
• Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
• Na ho na le likotsi tsa tlhahlobo?
• Liphetho li bolelang?
• Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea CK?
• Litšupiso

Teko ea creatine kinase (CK) ke eng?

Teko ena e lekanya palo ea creatine kinase (CK) maling. CK ke mofuta oa protheine, e tsejoang e le enzyme. E fumaneha haholo mesifa le pelo ea hau, e nang le bonyane bokong. Mesifa ea masapo ke mesifa e khomaretsoeng ke masapo a hao. Li sebetsa le masapo a hau ho u thusa ho sisinyeha le ho fa 'mele oa hau matla le matla. Mesifa ea pelo e pompa mali ka hare le kantle ho pelo.

Ho na le mefuta e meraro ea li-enzyme tsa CK:

• CK-MM, e fumanoang haholo mesifa ea masapo
• CK-MB, e fumanoang haholo mesifa ea pelo
• CK-BB, e fumanehang haholo liseleng tsa boko

Palo e nyane ea CK maling e tloaelehile. Chelete e phahameng e ka bolela bothata ba bophelo bo botle. Ho ipapisitse le mofuta le boemo ba CK bo fumanoeng, ho ka bolela hore o na le tšenyo kapa lefu la mesifa ea masapo, pelo kapa boko.

Mabitso a mang: CK, CK e felletseng, creatine phosphokinase, CPK

E sebelisetsoa eng?

Hangata ho sebelisoa tlhahlobo ea CK ho hlahloba le ho lekola likotsi le maloetse a mesifa. Maloetse ana a kenyelletsa:

• Muscular dystrophy, lefu le sa tloaelehang le futsitsoeng le bakang bofokoli, ho senyeha le ho felloa ke mosebetsi ha mesifa ea masapo. E etsahala haholo ho banna.
• Rhabdomyolis, ho senyeha ka potlako ha lisele tsa mesifa. E ka bakoa ke kotsi e mpe, lefu la mesifa kapa bokuli bo bong.

Teko e ka sebelisoa ho thusa ho fumana lefu la pelo, leha e se hangata haholo. Tlhahlobo ea CK e kile ea ba teko e tloaelehileng bakeng sa tlhaselo ea pelo. Empa tlhahlobo e 'ngoe, e bitsoang troponin, e fumanoe e le betere ha e fumana tšenyo ea pelo.

Hobaneng ha ke hloka tlhahlobo ea CK?

U kanna oa hloka tlhahlobo ea CK haeba u na le matšoao a lefu la mesifa. Tsena li kenyelletsa:

• Bohloko ba mesifa le / kapa cramps
• Bofokoli ba mesifa
• Mathata a leka-lekaneng
• Ho ba lerootho kapa ho hlohlona

U kanna ua hloka teko ena haeba u na le leqeba la mesifa kapa setorouku. Maemo a CK a kanna a se phahamele ho fihlela matsatsi a mabeli kamora likotsi tse itseng, ka hona o ka hloka ho lekoa makhetlo a 'maloa. Teko ena e ka thusa ho bonts'a haeba u na le tšenyo pelong ea hau kapa mesifa e meng.

Ho etsahalang nakong ea tlhahlobo ea CK?

Ngaka ea tlhokomelo ea bophelo e tla nka sampole ea mali mothapong o letsohong la hao, e sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ha o hloke litokisetso tse khethehileng bakeng sa tlhahlobo ea CK.

Na ho na le likotsi tsa tlhahlobo?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.

Liphetho li bolelang?

Haeba liphetho tsa hau li bontša hore o na le boemo bo phahameng ho feta bo tloaelehileng ba CK, ho ka bolela hore o na le kotsi kapa lefu la mesifa, pelo kapa boko. Ho fumana leseli le eketsehileng, mofani oa hau a ka odara liteko ho lekola maemo a li-enzyme tse khethehileng tsa CK:

• Haeba o na le li-enzyme tsa CK-MM tse phahameng ho feta tse tloaelehileng, ho ka bolela hore o na le kotsi ea mesifa kapa lefu, joalo ka muscular dystrophy kapa rhabdomyolis.
• Haeba u na le li-enzyme tsa CK-MB tse phahameng ho feta tse tloaelehileng, ho ka bolela hore u na le ho ruruha ha mesifa ea pelo kapa u na le lefu la pelo kapa haufinyane.
• Haeba u na le li-enzyme tsa CK-BB tse phahameng ho feta tse tloaelehileng, ho ka bolela hore u kile ua ba le stroke kapa kotsi ea boko.

Maemo a mang a ka bakang maemo a phahameng ho feta a tloaelehileng a CK a kenyelletsa:

• Ho koala mali
• Tšoaetso
• Mathata a Hormonal, ho kenyelletsa le mathata a qoqotho le litšoelesa tsa adrenal
• Ho buuoa nako e telele
• Meriana e itseng
• Ho ikoetlisa ka thata

Haeba u na le lipotso mabapi le liphetho tsa hau, bua le mofani oa tlhokomelo ea bophelo.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea CK?

Liteko tse ling tsa mali, joalo ka phanele ea electrolyte le liteko tsa ts'ebetso ea liphio, li ka laeloa hammoho le tlhahlobo ea CK.

Litšupiso

1. Likedare-Sinai [Inthanete]. Los Angeles: Likedare-Sinai; c2019. Mathata a Neuromuscular; [e qotsitsoeng ka la 2019 Phuptjane 12]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.cedars-sinai.edu/Patients/Health-Conditions/Neuromuscular-Disorders.aspx
2. KidsHealth ho tsoa Nemours [Inthaneteng]. Motheo oa Nemours; c1995-2019. Mesifa ea hao; [e qotsitsoeng ka 2019 Jun 19]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://kidshealth.org/en/kids/muscles.html
3. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2019. Moqapi Kinase (CK); [e ntlafalitsoeng 2019 ka la 3 Mots'eanong; e qotsitsoeng ka 2019 Jun 12]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/creatine-kinase-ck
4. Phetolelo ea Merck Manual Consumer [Inthanete]. Kenilworth (NJ): Merck & Co., Inc .; c2019. Liteko tsa Mathata a Musculoskeletal; [e ntlafalitsoeng 2017 Dec; e qotsitsoeng ka 2019 Jun 12]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho:
5. Mokhatlo oa Muscular Dystrophy [Internet]. Chicago: Mokhatlo oa Muscular Dystrophy; c2019. E boletse feela: Teko ea Creatine Kinase; 2000 Pherekhong 31 [e qotsitsoeng ka 2019 Phuptjane 12]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.mda.org/quest/article/simply-stated-the-creatine-kinase-test
6. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liteko tsa Mali; [qotsitsoeng 2019 Jun 12]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
7. Setsi sa Naha sa Mathata a Neurological le Stroke [Marang-rang]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Muscular Dystrophy: Tšepo ka ho etsa lipatlisiso; [e ntlafalitsoeng 2019 May 7; e qotsitsoeng ka 2019 Jun 12]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho:
8. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Gainesville (FL): Univesithi ea Florida Health; c2019. Bopa tlhahlobo ea phosphokinase: Kakaretso; [e ntlafalitsoeng 2019 Jun 12; e qotsitsoeng ka 2019 Jun 12]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/creatine-phosphokinase-test
9. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2019. Health Encyclopedia: Creatine Kinase (Madi); [qotsitsoeng 2019 Jun 12]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=167&ContentID=creatine_kinase_blood
10. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2019. Tlhahisoleseling ea Bophelo: Creatine Kinase: Kakaretso ea Teko; [e ntlafalitsoeng 2018 Jun 25; e qotsitsoeng ka 2019 Jun 12]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/medicaltest/creatine-kinase/abq5121.html
11. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2019. Tlhahisoleseling ea Bophelo: Creatine Kinase: Hobaneng ha e etsoa; [e ntlafalitsoeng 2018 Jun 25; e qotsitsoeng ka 2019 Jun 12]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/medicaltest/creatine-kinase/abq5121.html#abq5123

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.