Teko ea Ceruloplasmin

Litaba

• Teko ea ceruloplasmin ke eng?
• E sebelisetsoa eng?
• Hobaneng ha ke hloka tlhahlobo ea ceruloplasmin?
• Ho etsahalang nakong ea tlhahlobo ea ceruloplasmin?
• Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
• Na ho na le likotsi tsa tlhahlobo?
• Liphetho li bolelang?
• Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea ceruloplasmin?
• Litšupiso

Teko ea ceruloplasmin ke eng?

Tlhahlobo ena e lekanya boholo ba ceruloplasmin maling a hau. Ceruloplasmin ke protheine e entsoeng sebeteng. E boloka le ho nka koporo ho tsoa sebeteng ho e isa maling le likarolong tsa 'mele oa hau tse e hlokang.

Koporo ke diminerale e fumanoang lijong tse 'maloa, ho kenyelletsa linate, chokolete, li-mushroom, shellfish le sebete. E bohlokoa mesebetsing e mengata ea 'mele, ho kenyelletsa ho aha masapo a matla, ho hlahisa matla, le ho etsa melanin (ntho e fang letlalo' mala oa eona). Empa haeba u na le koporo e ngata haholo kapa e fokolang maling a hao, e ka ba sesupo sa bothata bo tebileng ba bophelo bo botle.

Mabitso a mang: CP, ceruloplasmin test ea mali, ceruloplasmin, serum

E sebelisetsoa eng?

Hangata ho sebelisoa tlhahlobo ea ceruloplasmin hammoho le liteko tsa koporo ho thusa ho fumana lefu la Wilson. Lefu la Wilson ke lefu le sa tloaelehang la liphatsa tsa lefutso le thibelang 'mele ho tlosa koporo e feteletseng. E ka baka pokello ea koporo e kotsi sebeteng, bokong le lithong tse ling.

E kanna ea sebelisoa ho fumana mathata a bakang khaello ea koporo (koporo e nyane haholo). Tsena li kenyelletsa:

• Khaello ea phepo e nepahetseng, boemo boo u sa fumaneng limatlafatsi tse lekaneng lijong tsa hau
• Malabsorption, boemo bo thatafalletsang 'mele oa hau ho monya le ho sebelisa limatlafatsi tseo u li jang
• Menkes syndrome, lefu le sa tloaelehang le le sa phekoleheng la liphatsa tsa lefutso

Ntle le moo, ka linako tse ling tlhahlobo e sebelisoa ho fumana lefu la sebete.

Hobaneng ha ke hloka tlhahlobo ea ceruloplasmin?

Mofani oa hao oa tlhokomelo ea bophelo a ka odara tlhahlobo ea ceruloplasmin haeba u na le matšoao a lefu la Wilson. Tsena li kenyelletsa:

• Khaello ea mali
• Jaundice (bosehla ba letlalo le mahlo)
• Ho nyekeloa
• Bohloko ba mpeng
• Mathata a ho kwenya le / kapa ho bua
• Litšisinyeho
• Ho tsamaea ka thata
• Liphetoho boitšoarong

U kanna ua hloka teko ena haeba u na le nalane ea lelapa ea lefu la Wilson, leha o sena matšoao. Hangata matšoao a hlaha lipakeng tsa lilemo tse 5 le 35, empa a ka hlaha pejana kapa hamorao bophelong.

U kanna oa ba le teko ena haeba u na le matšoao a khaello ea koporo (koporo e nyane haholo). Tsena li kenyelletsa:

• Letlalo le putswa
• Maemo a tlase ka mokhoa o sa tloaelehang oa lisele tse tšoeu tsa mali
• Osteoporosis, boemo bo bakang ho fokola ha masapo mme bo etsa hore a pepesehe ho robeha
• Mokhathala
• Ho khabisa matsoho le maoto

Ngoana oa hau a ka hloka tlhahlobo ena haeba a e-na le matšoao a Menkes syndrome. Matšoao hangata a hlaha bongoaneng mme a kenyelletsa:

• Moriri o brittle, sparse, le / kapa o kopaneng
• Mathata a ho fepa
• Ho hloleha ho hola
• Ho lieha ho ntlafatsa
• Ho hloka molumo oa mesifa
• Ho oa

Boholo ba bana ba nang le lefu lena ba shoa lilemong tse 'maloa tsa pele tsa bophelo, empa kalafo ea kapele e ka thusa bana ba bang ho phela halelele.

Ho etsahalang nakong ea tlhahlobo ea ceruloplasmin?

Ngaka ea tlhokomelo ea bophelo e tla nka sampole ea mali mothapong o letsohong la hao, e sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ha o hloke litokisetso tse khethehileng bakeng sa tlhahlobo ea ceruloplasmin.

Na ho na le likotsi tsa tlhahlobo?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.

Liphetho li bolelang?

Ceruloplasmin e tlase ho feta e tloaelehileng e ka bolela hore 'mele oa hau ha o khone ho sebelisa kapa ho felisa koporo hantle. E ka ba sesupo sa:

• Lefu la Wilson
• Lefu la Menkes
• Lefu la sebete
• Khaello ea phepo e nepahetseng
• Malabsorption
• Lefu la liphio

Haeba maemo a hau a ceruloplasmin a ne a phahame ho feta a tloaelehileng, ekaba lets'oao la:

• Tšoaetso e tebileng
• Lefu la pelo
• Ramatiki ea ramatiki
• Lefuemia
• Hodgkin lymphoma

Empa maemo a phahameng a ceruloplasmin le ona a ka bakoa ke maemo a sa hlokeng kalafo. Tsena li kenyelletsa bokhachane le ts'ebeliso ea lipilisi tsa thibelo ea bokhachane.

Haeba u na le lipotso mabapi le liphetho tsa hau, bua le mofani oa tlhokomelo ea bophelo.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea ceruloplasmin?

Liteko tsa Ceruloplasmin hangata li etsoa hammoho le liteko tse ling. Tsena li kenyelletsa liteko tsa koporo ho liteko tsa mali le / kapa moroto le sebete.

Litšupiso

1. Bukantswe ea Biology [Inthanete]. Bukantswe ea baeloji; c2019. Ceruloplasmin [e qotsitsoeng ka la 9 Phupu 18]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://biologydictionary.net/ceruloplasmin
2. Kliniki ea Cleveland [Inthanete]. Cleveland (OH): Kliniki ea Cleveland; c2019. Lefu la Wilson: Kakaretso [e qotsitsoeng ka 2019 Phupu 18]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://my.clevelandclinic.org/health/diseases/5957-wilson-disease
3. Hinkle J, Cheever K. Brunner & Suddarth's Handbook ea Liteko tsa Laboraro le Tlhatlhobo. 2nd Ed, mosa. Philadelphia: Wolters Kluwer Bophelo, Lippincott Williams & Wilkins; c2014. Ceruloplasmin; leq. EA-146-TL
4. Kaler SG, Holmes CS, Goldstein DS, Tang J, Godwin SC, Donsante A, Liew CJ, Sato S, Patronas N. Neonatal tlhahlobo le kalafo ea Mafu a Menkes. N Engl J Med [Inthanete]. 2008 Feb 7 [e qotsitsoeng ka 2019 Phupu 18]; EA-358 (6): 605–14. E fumaneha ho tsoa ho: https://www.ncbi.nlm.nih.gov/pubmed/18256395
5. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2019. Ceruloplasmin [e ntlafalitsoeng ka la 3 Mots'eanong 3; e qotsitsoeng ka la 9 Phupu 18]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/ceruloplasmin
6. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2019. Koporo [e ntlafalitsoeng ka la 3 Mots'eanong 3; e qotsitsoeng ka la 9 Phupu 18]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/copper
7. Mayo Clinic [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1998–2019. Lefu la Wilson: Ho hlahloba le ho phekola; 2018 Mar 7 [e qotsitsoeng ka 2019 Phupu 18]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.mayoclinic.org/diseases-conditions/wilsons-disease/diagnosis-treatment/drc-20353256
8. Mayo Clinic [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1998–2019. Lefu la Wilson: Matšoao le lisosa; 2018 Mar 7 [e qotsitsoeng ka 2019 Phupu 18]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.mayoclinic.org/diseases-conditions/wilsons-disease/symptoms-causes/syc-20353251
9. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liteko tsa Mali [e qotsitsoeng ka 2019 Jun 18]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
10. NIH Laeborari ea Naha ea Bongaka ea NIH U.S. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Lefu la Menkes; 2019 Jul 16 [e qotsitsoeng ka 2019 Phupu 18]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://ghr.nlm.nih.gov/condition/menkes-syndrome# tlhaloso
11. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Gainesville (FL): Univesithi ea Florida Health; c2019. Teko ea mali ea Ceruloplasmin: Kakaretso [e ntlafalitsoeng 2019 Jul 18; e qotsitsoeng ka la 9 Phupu 18]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/ceruloplasmin-blood-test
12. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Gainesville (FL): Univesithi ea Florida Health; c2019. Malabsorption: Kakaretso [e ntlafalitsoeng 2019 Jul 18; e qotsitsoeng ka la 9 Phupu 18]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/malabsorption
13. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Univesithi ea Florida; c2019. Khaello ea phepo e nepahetseng: Kakaretso; [e ntlafalitsoeng 2019 Jul 30; e qotsitsoeng ka la 2019 Phupu 30]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/malnutrition
14. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2019. Health Encyclopedia: Ceruloplasmin (Madi) [e qotsitswe ka 2019 Phupu 18]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=ceruloplasmin_blood
15. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2019. Health Encyclopedia: Kakaretso ea Koporo (Mali) [e qotsitsoeng ka la 9 Phupu 18]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=total_copper_blood
16. Meriana ea UR: Orthopedics le Ntlafatso [Marang-rang]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2019. Osteoporosis [e qotsitsoeng ka la 9 Phupu 18]. [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/orthopaedics/bone-health/osteoporosis.cfm

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.