Teko ea Calcitonin

Litaba

• Teko ea calcitonin ke eng?
• E sebelisetsoa eng?
• Hobaneng ha ke hloka tlhahlobo ea calcitonin?
• Ho etsahalang nakong ea tlhahlobo ea calcitonin?
• Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
• Na ho na le likotsi tsa tlhahlobo?
• Liphetho li bolelang?
• Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea calcitonin?
• Litšupiso

Teko ea calcitonin ke eng?

Tlhahlobo ena e lekanya boemo ba calcitonin maling a hau. Calcitonin ke hormone e entsoeng ke qoqotho ea hau, e nyenyane e bōpehileng joaloka serurubele e haufi le 'metso. Calcitonin e thusa ho laola hore na 'mele o sebelisa calcium joang. Calcitonin ke mofuta oa letšoao la hlahala. Matšoao a hlahala ke lintho tse entsoeng ke lisele tsa mofets'e kapa lisele tse tloaelehileng ho arabela mofets'e 'meleng.

Haeba calcitonin e ngata e fumanoa maling, e kanna ea ba sesupo sa mofuta oa mofetše oa qoqotho o bitsoang medullary thyroid cancer (MTC). Maemo a phahameng e kanna ea ba sesupo sa mafu a mang a qoqotho a ka u behang kotsing e kholo ea ho fumana MTC. Tsena li kenyelletsa:

• C-seleng hyperplasia, boemo bo bakang kholo e sa tloaelehang ea lisele tsa qoqotho
• Mefuta e mengata ea endocrine neoplasia mofuta oa 2 (MEN 2), lefu le sa tloaelehang, le futsitsoeng le bakang kholo ea lihlahala tsa qoqotho le litšoelesa tse ling tsamaisong ea endocrine. Sisteme ea endocrine ke sehlopha sa litšoelesa tse laolang mesebetsi e fapaneng ea bohlokoa, ho kenyeletsoa le kamoo 'mele oa hau o sebelisang le ho chesa matla (metabolism).

Mabitso a mang: thyrocalcitonin, CT, calcitonin ea motho, hCT

E sebelisetsoa eng?

Hangata calcitonin e sebelisoa ho:

• Thusa ho fumana lefu la kankere ea qoqotho ea C-cell hyperplasia le medullary
• Fumana hore na kalafo ea mofets'e oa kankere ea qoqotho ea sebetsa
• Fumana hore na mofetše oa kankere ea qoqotho o khutlile kamora kalafo
• Screen batho ba nang le nalane ea malapa ea li-endocrine neoplasia mofuta oa 2 (MEN 2). Nalane ea lelapa ea lefu lena e ka u beha kotsing e kholo ea ho tšoaroa ke mofetše oa qoqotho.

Hobaneng ha ke hloka tlhahlobo ea calcitonin?

U kanna ua hloka teko ena haeba u:

• Ba ntse ba phekoloa bakeng sa mofetše oa kankere ea qoqotho. Teko e ka bonts'a hore na kalafo ea sebetsa.
• U qetile kalafo ho bona hore na mofetše o khutlile.
• Eba le nalane ea lelapa ea BATHO 2.

U kanna ua hloka teko ena haeba u sa fumanoe u na le mofetše, empa u na le matšoao a lefu la qoqotho. Tsena li kenyelletsa:

• Leqhubu le ka pele la molala oa hau
• Ho ruruha li-lymph node molaleng oa hau
• Bohloko molaleng oa hau le / kapa molala
• Bothata ba ho kwenya
• Fetohela lentsoe la hau, joalo ka hoarsars

Ho etsahalang nakong ea tlhahlobo ea calcitonin?

Ngaka ea tlhokomelo ea bophelo e tla nka sampole ea mali mothapong o letsohong la hao, e sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

U kanna ua hloka ho itima lijo (u se ke ua ja kapa ua noa) lihora tse 'maloa pele ho tlhahlobo. Mofani oa hao oa tlhokomelo ea bophelo o tla u tsebisa haeba u hloka ho itima lijo le haeba ho na le litaelo tse khethehileng tseo u lokelang ho li latela.

Na ho na le likotsi tsa tlhahlobo?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali. U kanna oa ba le mahlaba a fokolang kapa ho longoa moo nale e kentsoeng teng, empa matšoao a mangata a fela kapele.

Liphetho li bolelang?

Haeba litekanyetso tsa hau tsa calcitonin li ne li phahame, ho ka bolela hore o na le C-cell hyperplasia kapa mofets'e oa kankere ea methapo. Haeba u se u ntse u alafshoa ke mofetše oa qoqotho, maemo a phahameng a ka bolela hore kalafo ha e sebetse kapa hore mofetše o khutlile kamora kalafo. Mefuta e meng ea mofetše, ho kenyelletsa mofetše oa sefuba, matšoafo le manyeme, le eona e ka baka maemo a phahameng a calcitonin.

Haeba maemo a hau a ne a phahame, o kanna oa hloka liteko tse ngata pele mofani oa tlhokomelo ea bophelo a ka etsa tlhahlobo. Liteko tsena li ka kenyelletsa skena ea qoqotho le / kapa biopsy. Sesepa sa qoqotho ke teko ea litšoantšo e sebelisang maqhubu a molumo ho sheba tšoelesa ea qoqotho. Biopsy ke ts'ebetso eo mofani oa tlhokomelo ea bophelo a ntšang karoloana ea lisele kapa lisele bakeng sa tlhahlobo.

Haeba litekanyetso tsa hau tsa calcitonin li ne li le tlase, ho ka bolela hore kalafo ea mofets'e ea sebetsa, kapa ha o na mofetše kamora kalafo.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea calcitonin?

Haeba u kile ua alafshoa ke mofetše oa qoqotho ea medullary, mohlomong u tla hlahlojoa khafetsa ho bona hore na kalafo e atlehile.

U ka fumana liteko tsa calcitonin khafetsa haeba u na le nalane ea lelapa ea mofuta oa endocrine neoplasia oa mofuta oa 2. Ho etsa liteko ho ka thusa ho fumana C-cell hyperplasia kapa mofets'e oa kankere ea qoqotho kapele kamoo ho ka khonehang. Ha mofetše o fumanoa kapele, ho bonolo ho a alafa.

Litšupiso

1. Mokhatlo oa American Cancer [Inthanete]. Atlanta: Mokhatlo oa Amerika oa Kankere Inc .; c2018. Liteko tsa Kankere ea Thyroid; [e ntlafalitsoeng 2016 Apr 15; e qotsitsoeng ka la 2018 Tlhakubele 20]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.cancer.org/cancer/thyroid-cancer/detection-diagnosis-staging/how-diagnosed.html
2. Mokhatlo oa American Cancer [Inthanete]. Atlanta: Mokhatlo oa Amerika oa Kankere Inc .; c2018. Kankere ea Thyroid ke Eng ?; [e ntlafalitsoeng 2016 Apr 15; e qotsitsoeng ka la 2018 Tlhakubele 20]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.cancer.org/cancer/thyroid-cancer/about/what-is-thyroid-cancer.html
3. Mokhatlo oa Amerika oa qoqotho [Inthanete]. Kereke ea Falls (VA): Mokhatlo oa Amerika oa Thyroid; c2018. Clinical Thyroidology bakeng sa Sechaba; [e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.thyroid.org/patient-thyroid-information/ct-for-patients/vol-3-issue-8/vol-3-issue-8-p-11-12
4. Hormone Health Network [Inthanete]. Mokhatlo oa Endocrine; c2018. Sisteme ea Endocrine; [e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.hormone.org/hormones-and-health/the-endocrine-system
5. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Calcitonin; [e ntlafalitsoeng 2017 Dec 4; e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/calcitonin
6. Mayo Clinic [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1998–2018. Kankere ea qoqotho: Tlhahlobo le phekolo; 2018 Mar 13 [e qotsitsoeng ka 2018 Phato 20]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.mayoclinic.org/diseases-conditions/thyroid-cancer/diagnosis-treatment/drc-20354167
7. Mayo Clinic [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1998–2018. Kankere ea qoqotho: Matšoao le lisosa; 2018 Mar 13 [e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.mayoclinic.org/diseases-conditions/thyroid-cancer/symptoms-causes/syc-20354161
8. Mayo Clinic: Mayo Medical Laboratories [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1995–2018. ID ea Teko: CATN: Calcitonin, Serum: Clinical and Interpretive; [e qotsitsoeng ka la 2018 Tlhakubele 20]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/9160
9. Mokhatlo oa Naha oa Kankere [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Bukana ea Tlhatlhobo ea Kankere ea NCI: biopsy; [e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/biopsy
10. Mokhatlo oa Naha oa Kankere [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Bukana ea Tlhatlhobo ea Kankere ea NCI: calcitonin; [e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/calcitonin
11. Mokhatlo oa Naha oa Kankere [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Bukana ea Kankere ea Kankere ea NCI: mafu a mangata a endocrine neoplasia type 2; [e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.cancer.gov/publications/dictionaries/cancer-terms/def/multiple-endocrine-neoplasia-type-2-syndrome
12. Mokhatlo oa Naha oa Kankere [Inthanete]. Bethesda (MD): U.S.Lefapha la Bophelo le Litšebeletso tsa Botho; Mofuta oa Kankere ea Bakuli ba Thyroid; [e qotsitsoeng ka la 2018 Tlhakubele 20]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho: https://www.cancer.gov/types/thyroid
13. Mokhatlo oa Naha oa Kankere [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Matšoao a Hlahala; [e qotsitsoeng ka la 2018 Tlhakubele 20]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis/tumor-markers-fact-sheet
14. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Liteko tsa Mali; [e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
15. Mokhatlo oa Naha oa Mathata a Rare [Marang-rang]. Danbury (CT): Mokhatlo oa Naha-oa Naha oa Mathata a Rare; c2018. Multiple Endocrine Neoplasia Mofuta oa 2; [e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://rarediseases.org/rare-diseases/multiple-endocrine-neoplasia-type
16. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Gainesville (FL): Univesithi ea Florida Health; c2018. Teko ea mali ea Calcitonin: Kakaretso; [e ntlafalitsoeng 2018 Dec 19; e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/calcitonin-blood-test
17. Bophelo ba UF: Univesithi ea Florida Health [Marang-rang]. Gainesville (FL): Univesithi ea Florida Health; c2018. Thyroid ultrasound: Kakaretso; [e ntlafalitsoeng 2018 Dec 19; e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://ufhealth.org/thyroid-ultrasound
18. Setsi sa Bongaka sa Rochester [Internet]. Rochester (NY): Setsi sa Bongaka sa Univesithi ea Rochester; c2018. Health Encyclopedia: Calcitonin; [e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=calcitonin
19. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2018. Tlhahisoleseling ka Bophelo: Ho matlafatsa metabolism ea hau: Kakaretso ea sehlooho; [e ntlafalitsoeng 2017 Oct 9; e qotsitsoeng ka la 2018 Tlhakubele 20]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/special/boosting-your-metabolism/abn2424.html

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.