Tlhahlobo ea Beta 2 Microglobulin (B2M)

Litaba

• Teko ea letšoao la beta-2 microglobulin tumor mark ke eng?
• E sebelisetsoa eng?
• Hobaneng ha ke hloka tlhahlobo ea "mark-beta microglobulin" marker test?
• Ho etsahalang nakong ea tlhahlobo ea "beta-2" microglobulin tumor marker?
• Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?
• Na ho na le likotsi tsa tlhahlobo?
• Liphetho li bolelang?
• Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea "beta-2" microglobulin tumor marker?
• Litšupiso

Teko ea letšoao la beta-2 microglobulin tumor mark ke eng?

Teko ena e lekanya palo ea protheine e bitsoang beta-2 microglobulin (B2M) maling, morong, kapa cerebrospinal fluid (CSF). B2M ke mofuta oa letšoao la hlahala. Matšoao a hlahala ke lintho tse entsoeng ke lisele tsa mofets'e kapa lisele tse tloaelehileng ho arabela mofets'e 'meleng.

B2M e fumaneha ka holim'a lisele tse ngata 'me e lokolloa' meleng. Batho ba phetseng hantle ba na le B2M e nyane maling le morong oa bona.

• Batho ba nang le mofetše oa masapo le mali hangata ba na le maemo a phahameng a B2M maling kapa morong oa bona. Kankere ena e kenyelletsa mefuta e mengata ea myeloma, lymphoma le kankere ea mali.
• Mefuta e phahameng ea B2M ka mokelikeli oa cerebrospinal e ka bolela hore mofets'e o nametse bokong le / kapa mokokotlong.

Ha ho sebelisoe tlhahlobo ea tšoaetso ea hlahala ea B2M ho fumana mofetše. Empa e ka fana ka tlhaiso-leseling ea bohlokoa ka mofets'e oa hau, ho kenyeletsoa hore na o tebile hakae le hore na o tla hola joang nakong e tlang.

Mabitso a mang: kakaretso ea beta-2 microglobulin, β2-microglobulin, B2M

E sebelisetsoa eng?

Hangata beta-microglobulin test mark test e fuoa batho ba fumanoeng ba e-na le mofetše o itseng oa moko kapa mali. Teko e ka sebelisoa ho:

• Fumana boima ba kankere le hore na e nametse. Ts'ebetso ena e tsejoa e le sethaleng sa mofets'e. Ha boemo bo phahama, kankere e tsoetse pele haholo.
• Bolela tsoelo-pele ea mafu le kalafo ea tataiso.
• Bona hore na kalafo ea mofetše e ea sebetsa.
• Bona hore na mofetše o nametse bokong le mokokotlong.

Hobaneng ha ke hloka tlhahlobo ea "mark-beta microglobulin" marker test?

U kanna ua hloka teko ena haeba u fumanoe u na le myeloma, lymphoma kapa leukemia. Teko e ka bonts'a sethaleng sa mofetše oa hau le hore na kalafo ea mofets'e ea sebetsa.

Ho etsahalang nakong ea tlhahlobo ea "beta-2" microglobulin tumor marker?

Teko ea "beta-2" microglobulin hangata e le tlhahlobo ea mali, empa e kanna ea fanoa joalo ka tlhahlobo ea moroto ea lihora tse 24, kapa tlhahlobo ea cerebrospinal fluid (CSF).

Bakeng sa teko ea mali, setsebi sa tlhokomelo ea bophelo se tla nka sampole ea mali mothapong o letsohong la hao, a sebelisa nale e nyane. Kamora hore nalete e kenngoe, ho tla bokelloa mali a manyane ka har'a pompo ea liteko. U ka ikutloa u hlaba hanyane ha nale e kena kapa e tsoa. Hangata hona ho nka nako e ka tlase ho metsotso e mehlano.

Bakeng sa sampole ea lihora tse 24 tsa moroto, mofani oa hao oa tlhokomelo ea bophelo kapa setsebi sa laboratori o tla u fa setshelo ho bokella moroto oa hau le litaelo tsa hore na u ka bokella le ho boloka mehlala ea hau joang. Teko ea sampole ea lihora tse 24 ea moroto hangata e kenyelletsa mehato e latelang:

• Hlakola senya ea hao hoseng 'me u ntše metsi ao. Ngola nako.
• Bakeng sa lihora tse 24 tse latelang, boloka moroto oa hau kaofela ka setshelong se fanoeng.
• Boloka setshelo sa hau sa moroto ka sehatsetsing kapa se pholileng se nang le leqhoa.
• Khutlisetsa setshelo sa sampole ofising ea mofani oa bophelo bo botle kapa laboratoring joalokaha ho laetsoe.

Bakeng sa tlhahlobo ea cerebrospinal fluid (CSF), sampole ea mokelikeli oa mokokotlo o tla bokelloa ka mokhoa o bitsoang pompong ea mokokotlo (e tsejoang hape e le ho phunya lumbar). Hangata pompo ea mokokotlo e etsoa sepetlele. Nakong ea ts'ebetso:

• U tla robala ka lehlakore kapa u lule tafoleng ea litlhahlobo.
• Mofani oa tlhokomelo ea bophelo o tla u hlatsoa mokokotlo ebe o kenya moriana o thethefatsang letlalo letlalong, ka hona o ke ke oa utloa bohloko nakong ea ts'ebetso. Mofani oa hau a ka beha tranelate ea mokokotlo mokokotlong oa hau pele ho ente ena.
• Hang ha sebaka se mokokotlong oa hau se senyehile ka ho feletseng, mofani oa hau o tla kenya nale e tšesaane, e sekoti pakeng tsa li-vertebrae tse peli mokokotlong oa hau o tlase. Vertebrae ke masapo a mokokotlo a manyane a etsang mokokotlo oa hau.
• Mofani oa hau o tla hula mokelikeli o monyane oa cerebrospinal bakeng sa tlhahlobo. Sena se tla nka metsotso e ka bang mehlano.
• U tla hloka ho lula u khutsitse haholo ha metsi a ntse a huloa.
• Mofani oa hau a ka u kopa hore u robale ka mokokotlo hora kapa tse peli kamora ts'ebetso. Sena se ka u thibela ho tšoaroa ke hlooho hamorao.

Na ke tla hloka ho etsa eng kapa eng ho itokisetsa tlhahlobo?

Ha o hloke litokisetso tse khethehileng bakeng sa teko ea mali kapa moroto.

Ha o hloke litokisetso tse khethehileng bakeng sa tlhahlobo ea CSF, empa o kanna oa kopuoa ho tšolla senya le mala pele ho tlhahlobo.

Na ho na le likotsi tsa tlhahlobo?

Ho na le kotsi e nyane haholo ea ho etsa tlhahlobo ea mali kapa moroto. Kamora tlhahlobo ea mali, o kanna oa ba le bohloko bo nyane kapa likotlo sebakeng seo nale e kentsoeng ho sona, empa matšoao a mangata a fela kapele.

Ho na le kotsi e nyane haholo ea ho ba le pompo ea mokokotlo. U kanna oa utloa pini kapa khatello ha nale e kentsoe. Kamora tlhahlobo, o ka ba le hlooho e opang, e bitsoang hlooho ea "post-lumbar" Hoo e ka bang motho a le mong ho ba leshome o tla ba le hlooho e bohloko ea "post-lumbar". Sena se ka nka lihora tse 'maloa kapa beke kapa ho feta. Haeba u tšoeroe ke hlooho e tšoarellang nako e telele ho feta lihora tse 'maloa, buisana le mofani oa tlhokomelo ea bophelo. A ka tseba ho fana ka kalafo ho imolla bohloko. U ka utloa bohloko kapa bonolo mokokotlong oa hau sebakeng seo nale e kentsoeng ho sona. U kanna oa ba le ho tsoa mali sebakeng seo.

Liphetho li bolelang?

Haeba tlhahlobo e sebeliselitsoe ho fumana hore na mofetše oa hau o tsoetse pele hakae (sethala sa mofets'e), liphetho li kanna tsa bontša hore na mofetše o kae 'meleng oa hau le hore na o ka ata.

Haeba tlhahlobo ea B2M e sebelisitsoe ho lekola hore na kalafo ea hau e sebetsa hantle hakae, liphetho tsa hau li ka bonts'a:

• Methati ea hau ea B2M ea eketseha. Sena se ka bolela hore mofetše oa hau oa ata, mme / kapa kalafo ea hau ha e sebetse.
• Methati ea hau ea B2M ea fokotseha. Sena se ka bolela hore kalafo ea hau ea sebetsa.
• Methati ea hau ea B2M ha ea eketseha kapa ho fokotseha. Sena se ka bolela hore lefu la hau le tsitsitse.
• Maemo a hau a B2M a fokotsehile, empa hamorao a eketseha. Sena se ka bolela hore mofetše oa hau o khutlile kamora hore o phekoloe.

Haeba u na le lipotso mabapi le liphetho tsa hau, bua le mofani oa tlhokomelo ea bophelo.

Ithute haholoanyane ka liteko tsa laboratori, libaka tsa litšupiso, le liphetho tsa kutloisiso.

Na ho na le eng kapa eng eo ke hlokang ho e tseba ka tlhahlobo ea "beta-2" microglobulin tumor marker?

Liteko tsa Beta-2 tsa microglobulin ha li sebelisoe hangata joalo ka liteko tsa hlahala bakeng sa bakuli ba mofets'e. Methati ea B2M ka linako tse ling e lekanyetsoa ho:

• Lekola tšenyo ea liphio ho batho ba nang le lefu la liphio.
• Fumana hore na tšoaetso ea vaerase, joalo ka HIV / AIDS, e amme boko le / kapa lesapo la mokokotlo.
• Hlahloba ho bona hore na lefu le tsoetse pele ho batho ba nang le multiple sclerosis, lefu le sa foleng le amang boko le lesapo la mokokotlo.

Litšupiso

1. Allina Health [Inthanete]. Minneapolis: Bophelo bo Botle ba Allina; Tekanyo ea Beta 2 microglobulin; [e ntlafalitsoeng 2016 Mar 29; e qotsitsoeng 2018 Jul 28]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://account.allinahealth.org/library/content/49/150155
2. Mokhatlo oa American Cancer [Inthanete]. Atlanta: Mokhatlo oa Amerika oa Kankere Inc .; c2018. Sethaleng sa Kankere; [e nchafalitsoeng 2015 Mar 25; e qotsitsoeng 2018 Jul 28]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.cancer.org/treatment/understanding-your-diagnosis/staging.html
3. Mokhatlo oa American Cancer [Inthanete]. Atlanta: Mokhatlo oa Amerika oa Kankere Inc .; c2018. Mehato e mengata ea Myeloma; [e ntlafalitsoeng 2018 Feb 28; e qotsitsoeng 2018 Jul 28]; [li-skrini tse ka bang 5]. E fumaneha ho tsoa ho: https://www.cancer.org/cancer/multiple-myeloma/detection-diagnosis-staging/staging.html
4. Bagnoto F, Durastanti V, Finamore L, Volante G, Millefiorini E. Beta-2 microglobulin le neopterin e le matšoao a ts'ebetso ea mafu ho multiple sclerosis. Neurol Sci [Inthaneteng]. 2003 Dec [e qotsitsoeng 2018 Jul 28] ;; 24 (5): s301 – s304. E fumaneha ho tsoa ho: https://link.springer.com/article/10.1007%2Fs10072-003-0180-5
5. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Mohlala oa Urine ea Lihora tse 24; [e ntlafalitsoeng 2017 Jul 10; e qotsitsoeng 2018 Jul 28]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/glossary/urine-24
6. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Beta-2 Microglobulin Mafu a Liphio; [e ntlafalitsoeng 2018 Jan 24; e qotsitsoeng 2018 Jul 28]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/beta-2-microglobulin-kidney-disease
7. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Beta-2 Microglobulin Tumor Marker; [e ntlafalitsoeng 2017 Dec 4; e qotsitsoeng 2018 Jul 28]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/beta-2-microglobulin-tumor-marker
8. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Tlhatlhobo ea Cerebrospinal Fluid (CSF); [e ntlafalitsoeng 2018 Feb 2; e qotsitsoeng 2018 Jul 28]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/tests/cerebrospinal-fluid-csf-analysis
9. Liteko tsa Lab Marang-rang [Inthaneteng]. Washington DC: Mokhatlo oa Amerika oa Clinical Chemistry; c2001–2018. Multiple sclerosis; [e ntlafalitsoeng 2018 May 16; e qotsitsoeng 2018 Jul 28]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://labtestsonline.org/conditions/multiple-sclerosis
10. Mayo Clinic [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1998–2018. Multiple myeloma: Tlhahlobo le kalafo; 2017 Dec 15 [e qotsitsoeng ka 2018 Phupu 28]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.mayoclinic.org/diseases-conditions/multiple-myeloma/diagnosis-treatment/drc-20353383
11. Mayo Clinic: Mayo Medical Laboratories [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1995–2018. ID ea Teko: B2M: Beta-2 Microglobulin (Beta-2-M), Serum: Clinical and Interpretive; [e qotsitsoeng ka 2018 Phupu 28]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/9234
12. Mayo Clinic: Mayo Medical Laboratories [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1995–2018. ID ea Teko: B2MC: Beta-2 Microglobulin (Beta-2-M), Mokelikeli oa Mokokotlo: Kliniki le Tlhaloso; [e qotsitsoeng ka 2018 Phupu 28]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/60546
13. Mayo Clinic: Mayo Medical Laboratories [Inthaneteng]. Motheo oa Mayo oa Thuto ea Bongaka le Patlisiso; c1995–2018. ID ea Teko: B2MU: Beta-2 Microglobulin (B2M), Urine: Clinical and Interpretive; [e qotsitsoeng ka 2018 Phupu 28]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/602026
14. Phetolelo ea Merck Manual Consumer [Inthanete]. Kenilworth (NJ): Merck & Co Inc .; c2018. Tlhahlobo ea Kankere; [e qotsitsoeng ka 2018 Phupu 28]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.merckmanuals.com/home/cancer/overview-of-cancer/diagnosis-of-cancer
15. Phetolelo ea Merck Manual Consumer [Inthanete]. Kenilworth (NJ): Merck & Co Inc .; c2018. Liteko tsa Brain, Spinal Cord, le Mathata a Metsing; [e qotsitsoeng ka 2018 Phupu 28]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.merckmanuals.com/home/brain,-spinal-cord,-and-nerve-disorders/diagnosis-of-brain,-spinal-cord,-and-nerve-disorders/tests-for -bongo, -e leng mokokotlong, -le-methapo-kutlo
16. Mokhatlo oa Naha oa Kankere [Inthanete]. Bethesda (MD): Lefapha la Bophelo le Litšebeletso tsa Botho la U.S. Matšoao a Hlahala; [e qotsitsoeng ka 2018 Phupu 28]; [hoo e ka bang li-skrini tse 4]. E fumaneha ho tsoa ho: https://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis/tumor-markers-fact-sheet
17. National Heart, Lung, le Setsi sa Mali [Internet]. Bethesda (MD): U.S.Lefapha la Bophelo le Litšebeletso tsa Botho; Liteko tsa Mali; [e qotsitsoeng ka 2018 Phupu 28]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.nhlbi.nih.gov/health-topics/blood-tests
18. Oncolink [Inthanete]. Philadelphia: Batlhokomedi ba Yunibesithi ya Pennsylvania; c2018. Tataiso ea Mamello ho Matšoao a Hlahala; [e ntlafalitsoeng 2018 Mar 5; e qotsitsoeng 2018 Jul 28]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.oncolink.org/cancer-treatment/procedures-diagnostic-tests/blood-tests-tumor-diagnostic-tests/patient-guide-to-tumor-markers
19. Science Direct [Inthaneteng]. Elsevier BV ;; c2018. Beta-2 microglobulin; [e qotsitsoeng ka 2018 Phupu 28]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/beta-2-microglobulin
20. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2018. Tlhahisoleseling ea bophelo bo botle: Lintlha tsa bophelo bo botle bakeng sa hau: Pokello ea Lihora tse 24; [e ntlafalitsoeng 2016 Oct 20; e qotsitsoeng 2018 Jul 28]; [li-skrini tse ka bang 3]. E fumaneha ho tsoa ho: https://www.uwhealth.org/healthfacts/diagnostic-tests/4339.html
21. Bophelo ba UW [Marang-rang]. Madison (WI): Univesithi ea Wisconsin Lipetlele le Bolaoli ba Litleliniki; c2018. Matšoao a Hlahala: Kakaretso ea Sehlooho; [e ntlafalitsoeng ka la 3 Mots'eanong 3; e qotsitsoeng 2018 Jul 28]; [li-skrini tse ka bang 2]. E fumaneha ho tsoa ho: https://www.uwhealth.org/health/topic/special/tumor-marker-tests/abq3994.html

Tlhahisoleseling e fumanehang sebakeng sena sa marang-rang ha ea lokela ho sebelisoa ho nka sebaka sa tlhokomelo ea bongaka le likeletso. Ikopanye le mofani oa tlhokomelo ea bophelo haeba u na le lipotso ka bophelo ba hau.