Niacinamide

Litaba

• E ka sebetsa hantle bakeng sa ...
• Mohlomong e sebetsa bakeng sa ...
• Mohlomong ha e na thuso bakeng sa ...
• Bopaki bo sa lekaneng ba ho lekanya katleho ea ...
• Litlhokomelo le litemoso tse khethehileng:

Ho na le mefuta e 'meli ea vithamine B3. Mofuta o mong ke niacin, o mong ke niacinamide. Niacinamide e fumanoa lijong tse ngata ho kenyelletsa tomoso, nama, tlhapi, lebese, mahe, meroho e metala, linaoa le lijo-thollo. Niacinamide e boetse e fumanoa liholong tse ngata tse tlatselletsang tsa vithamine B le livithamini tse ling tsa B. Niacinamide e ka boela ea thehoa 'meleng ho tsoa ho niacin ea phepo.

Se ke oa ferekanya niacinamide le niacin, NADH, nicotinamide riboside, inositol nicotinate, kapa tryptophan. Bona lenane le arohaneng la lihlooho tsena.

Niacinamide e nkoa ka molomo bakeng sa ho thibela khaello ea vithamine B3 le maemo a amanang le eona a kang pellagra. E boetse e nkoa ka molomo bakeng sa makhopho, lefu la tsoekere, mofetše oa molomo, lefu la masapo le mafu a mang a mangata. Leha ho le joalo, ha ho na bopaki bo botle ba mahlale bo tšehetsang ts'ebeliso ena.

Niacinamide e boetse e sebelisoa letlalong la makhopho, eczema le maemo a mang a letlalo. Hape ha ho na bopaki bo botle bo tšehetsang ts'ebeliso ena.

Meriana ea Tlhahisoleseling e Akaretsang e sebetsa hantle ho ipapisitsoe le bopaki ba mahlale ho latela sekala se latelang: E ​​ea sebetsa, e ka sebetsa hantle, mohlomong ea sebetsa, mohlomong e sa sebetse, mohlomong e sa sebetse, e sa sebetse ebile e sa lekana Bopaki bo lokelang ho lekanyetsoa.

Likarolo tsa katleho ea NIACINAMIDE ke tse latelang:

E ka sebetsa hantle bakeng sa ...

• Lefu le bakoang ke khaello ea niacin (pellagra). Niacinamide e amoheloa ke Tsamaiso ea Lijo le Lithethefatsi ea U.S. (FDA) bakeng sa ts'ebeliso ena. Ka linako tse ling Niacinamide e ratoa ho feta niacin hobane ha e bake "ho hohola," (bofubelu, ho hlohlona le ho hlohlona), litlamorao tsa kalafo ea niacin.

Mohlomong e sebetsa bakeng sa ...

• Makhopho. Patlisiso ea pejana e bonts'a hore ho noa matlapa a nang le niacinamide le lisebelisoa tse ling bakeng sa libeke tse 8 ho ntlafatsa ponahalo ea letlalo ho batho ba nang le makhopho. Phuputso e 'ngoe e bonts'a hore ho sebelisa tranelate e nang le niacinamide ho ntlafatsa ponahalo ea letlalo ho batho ba nang le makhopho.
• Lefu la tsoekere. Liphuputso tse ling li bonts'a hore ho nka niacinamide ho ka thusa ho thibela tahlehelo ea tlhahiso ea insulin ho bana le ho batho ba baholo ba kotsing ea lefu la tsoekere la mofuta oa 1. E kanna ea boela ea thibela ho lahleheloa ke tlhahiso ea insulin le ho fokotsa lethal dose ea insulin e hlokoang ke bana ba sa tsoa fumanoa ba na le lefu la tsoekere la mofuta oa 1. Leha ho le joalo, niacinamide ha e bonahale e thibela kholo ea lefu la tsoekere la mofuta oa 1 ho bana ba kotsing. Ho batho ba nang le lefu la tsoekere la mofuta oa 2, niacinamide e bonahala e thusa ho sireletsa tlhahiso ea insulin le ho ntlafatsa taolo ea tsoekere maling.
• Maemo a phahameng a phosphate maling (hyperphosphatemia). Litekanyetso tse phahameng tsa mali a phosphate li ka bakoa ke ts'ebetso e fokotsehileng ea liphio. Ho batho ba nang le ho hloleha ha liphio ba leng ho hemodialysis mme ba na le phosphate e phahameng ea mali, ho nka niacinamide ho bonahala ho thusa ho fokotsa maemo a phosphate ha ho nkuoa le li-binders tsa phosphate kapa ntle le tsona.
• Kankere ea hlooho le molala. Phuputso e bonts'a hore ho nka niacinamide ha o ntse o fumana radiotherapy le mofuta oa kalafo o bitsoang carbogen ho ka thusa ho laola kholo ea hlahala le ho eketsa ho pholoha ho batho ba bang ba nang le mofetše oa larynx. Ho nka niacinamide ha o ntse o fumana radiotherapy le carbogen ho bonahala ho thusa batho ba nang le mofetše oa larynx bao le bona ba nang le phokolo ea mali. Ho bonahala hape e thusa batho ba nang le lihlahala tse hlokang oksijene.
• Kankere ea letlalo. Ho nka niacinamide ho bonahala ho thusa ho thibela mofetše o mocha oa letlalo kapa matheba a pele ho nako (actinic keratosis) ho tloha ho batho ba nang le nalane ea mofets'e oa letlalo kapa actinic keratosis.
• Osteoarthritis. Ho nka niacinamide ho bonahala ho ntlafatsa ho fetoha ha 'mele le ho fokotsa bohloko le ho ruruha ho batho ba nang le lefu la masapo. Hape, batho ba bang ba nang le lefu la osteoarthritis ba nkang niacinamide ba ka hloka ho noa meriana e fokolang ea bohloko.

Mohlomong ha e na thuso bakeng sa ...

• Hlahala ea boko. Patlisiso ea pejana e bonts'a hore ho phekola batho ba nang le lihlahala tsa boko tse tlositsoeng opereishene ka niacinamide, radiotherapy, le carbogen ha ho ntlafatse ho phela ha ho bapisoa le radiotherapy kapa radiotherapy le carbogen.
• Kankere ea senya. Ho phekola batho ba nang le mofetše oa senya ka niacinamide, radiotherapy, le carbogen ha ho bonahale ho fokotsa kholo ea hlahala kapa ho ntlafatsa pholoho ha ho bapisoa le radiotherapy kapa radiotherapy le carbogen.

Bopaki bo sa lekaneng ba ho lekanya katleho ea ...

• Lefu la mahlo le lebisang ho tahlehelo ea pono ho batho ba baholo (ho holofala ha macular kapa AMD). Phuputso ea pejana e fana ka maikutlo a hore ho nka niacinamide, vithamine E, le lutein selemo ho ntlafatsa tsela eo retina e sebetsang ka eona ho batho ba nang le tahlehelo ea pono e amanang le lilemo ka lebaka la tšenyo ea leihlo.
• Letlalo le tsofalang. Phuputso ea pejana e bonts'a hore ho sebelisa tranelate e nang le 5% niacinamide sefahlehong ho ntlafatsa ho fifala, ho sosobana, ho tiea le bofubelu ho basali ba nang le letlalo le tsofetseng ka lebaka la tšenyo ea letsatsi.
• Eczema (atopic dermatitis). Patlisiso ea pejana e bonts'a hore ho sebelisa tranelate e nang le 2% niacinamide ho fokotsa tahlehelo ea metsi le ho ntlafatsa metsi, le ho fokotsa bofubelu le ho nyoloha, ho batho ba nang le eczema.
• Tlhokomelo ea tlhokomelo-lefu la ho se sebetse hantle (ADHD). Ho na le bopaki bo loantšanang mabapi le bohlokoa ba niacinamide hammoho le livithamini tse ling bakeng sa kalafo ea ADHD.
• Bofubelu ba letlalo bo bakoang ke kotsi kapa ho halefa (erythema). Phuputso ea pejana e bonts'a hore ho sebelisa tranelate e nang le niacinamide ho fokotsa bofubelu ba letlalo, ho omella le ho hlohlona ho bakoang ke moriana oa makhopho isotretinoin.
• Lefu la nako e telele la liphio (lefu le sa foleng la liphio kapa CKD). Phuputso ea pejana e bonts'a hore ho nka niacinamide ha ho thuse ho fokotsa ho hlohlona ho batho ba nang le lefu la liphio.
• Matlalo a lefifi sefahlehong (melasma). Phuputso ea pejana e bonts'a hore ho sebelisa moisturizer e nang le 5% niacinamide kapa 2% niacinamide e nang le 2% tranexamic acid bakeng sa libeke tse 4-8 ho thusa ho bonesa letlalo ho batho ba nang le matheba a lefifi a letlalo.
• Kankere e qalang ka lisele tse tšoeu tsa mali (e seng Hodgkin lymphoma). Phuputso ea pele e bonts'a hore ho nka niacinamide e le karolo ea kalafo ka sethethefatsi se bitsoang vorinostat ho ka thusa batho ba nang le lymphoma ho ea tšoarelong.
• Boemo ba letlalo bo bakang bofubelu sefahlehong (rosacea). Phuputso ea pejana e bonts'a hore ho noa matlapa a nang le niacinamide le lisebelisoa tse ling bakeng sa libeke tse 8 ho ntlafatsa ponahalo ea letlalo ho batho ba nang le rosacea.
• Letlalo le bohale, le letlalo la letlalo le sefahleho (seborrheic dermatitis). Phuputso ea pejana e bonts'a hore ho sebelisa tranelate e nang le 4% niacinamide ho ka fokotsa bofubelu le ho nyoloha ha letlalo ho batho ba nang le seborrheic dermatitis.
• Botahoa.
• Lefu la Alzheimer.
• Ramatiki.
• Fokotsa bokhoni ba ho hopola le ho nahana bo etsahalang ka mokhoa o tloaelehileng le lilemo.
• Ho tepella maikutlo.
• Khatello ea mali e phahameng.
• Bokudi ba motsamao.
• Lefu la Premenstrual (PMS).
• Maemo a mang.

Bopaki bo eketsehileng boa hlokahala ho lekola niacinamide bakeng sa ts'ebeliso ena.

Niacinamide e ka etsoa ka niacin 'meleng. Niacin e fetoloa niacinamide ha e nooa ka bongata bo fetang ba se hlokoang ke 'mele. Niacinamide e qhibiliha habonolo ka metsing 'me e monya hantle ha e nkuoa ka molomo.

Niacinamide ea hlokahala bakeng sa tšebetso e nepahetseng ea mafura le tsoekere 'meleng le ho boloka lisele tse phetseng hantle.

Ho fapana le niacin, niacinamide ha e na litlamorao tse ntle ho mafura mme ha ea lokela ho sebelisoa ho phekola k'holeseterole e phahameng kapa mafura a mangata maling. Ha e nkoa ka molomo: Niacinamide ke TŠOANANG POLOKO bakeng sa batho ba baholo ba bangata ha ba nooa ka bongata bo khothalletsoang. Ho fapana le niacin, niacinamide ha e bake ho hohola. Leha ho le joalo, niacinamide e ka baka litla-morao tse nyane tse kang ho halefa ke mpa, khase, ho tsekela, ho hlohlona, ​​ho hlohlona le mathata a mang. Ho fokotsa kotsi ea litla-morao tsena, batho ba baholo ba lokela ho qoba ho nka niacinamide ka tekanyetso e fetang 35 mg ka letsatsi.

Ha ho nkoa litekanyetso tsa ligrama tse fetang 3 ka letsatsi la niacinamide, litla-morao tse tebileng li ka etsahala. Tsena li kenyelletsa mathata a sebete kapa tsoekere e phahameng maling.

Ha e sebelisoa letlalong: Niacinamide ke MOTS'ELISI TS'IU. Setlolo sa Niacinamide se ka baka ho cha, ho hlohlona kapa bofubelu bo bobebe.

Litlhokomelo le litemoso tse khethehileng:

Bokhachane le ho anyesa: Niacinamide ke TŠOANANG POLOKO bakeng sa bakhachane le ba anyesang ha ba nooa ka bongata bo khothalletsoang. Palo e phahameng e khothalletsoang ea niacin bakeng sa basali ba baimana kapa ba anyesang ke 30 mg ka letsatsi bakeng sa basali ba ka tlase ho lilemo tse 18, le 35 mg ka letsatsi bakeng sa basali ba ka holimo ho lilemo tse 18.

Bana: Niacinamide ke TŠOANANG POLOKO ha e nkoa ka molomo ka chelete e khothalletsoang bakeng sa sehlopha ka seng sa lilemo. Empa bana ba lokela ho qoba ho noa li-niacinamide kaholimo ho meeli e kaholimo ea letsatsi, e leng 10 mg bakeng sa bana ba lilemo li 1-3, 15 mg bakeng sa bana ba lilemo li 4-8, 20 mg bakeng sa bana ba lilemo li 9-13, le 30 mg bakeng sa bana ba lilemo li 14-18.

Maloetse: Niacinamide e ka etsa hore ho kula ho be matla le ho feta hobane e etsa hore histamine, khemik'hale e ikarabellang bakeng sa matšoao a kulisang, e lokolloe.

Lefu la tsoekere: Niacinamide e ka eketsa tsoekere maling. Batho ba nang le lefu la tsoekere ba nkang niacinamide ba lokela ho hlahloba tsoekere ea mali ka hloko.

Lefu la gallbladder: Niacinamide e ka mpefatsa lefu la gallbladder.

Gout: Niacinamide e ngata e ka tlisa gout.

Dialysis ea liphio: Ho nka niacinamide ho bonahala ho eketsa menyetla ea ho ba le liplatelete tse tlase tsa mali ho batho ba nang le ho hloleha ha liphio ba leng ho dialysis.

Lefu la sebete: Niacinamide e ka eketsa tšenyo ea sebete. U se ke ua e sebelisa haeba u e-na le lefu la sebete.

Diso tsa ka maleng kapa mala: Niacinamide e ka mpefatsa liso. U se ke ua e sebelisa haeba u na le liso.

Phekolo: Niacinamide e ka kena-kenana le taolo ea tsoekere maling nakong le kamora 'opereishene. Khaotsa ho nka niacinamide bonyane libeke tse 2 pele ho opereishene e reriloeng.

E itekanetse

E-ba hlokolosi ka motsoako ona.

Carbamazepine (Tegretol)

Carbamazepine (Tegretol) e robehile ke 'mele. Ho na le matšoenyeho a mang a hore niacinamide e ka fokotsa hore na 'mele o senya carbamazepine (Tegretol) kapele hakae. Empa ha ho na leseli le lekaneng ho tseba hore na sena se bohlokoa.

Meriana e ka lematsang sebete (lithethefatsi tsa Hepatotoxic)

Niacinamide e ka lematsa sebete, haholo ha e sebelisoa ka tekanyetso e phahameng. Ho nka niacinamide hammoho le meriana e ka lematsang sebete ho ka eketsa menyetla ea ho senyeha ha sebete. Se ke oa nka niacinamide haeba u noa moriana o ka lematsang sebete.

Meriana e meng e ka lematsang sebete e kenyelletsa acetaminophen (Tylenol le tse ling), amiodarone (Cordarone), carbamazepine (Tegretol), isoniazid (INH), methotrexate (Rheumatrex), methyldopa (Aldomet), fluconazole (Diflucan), itraconazole (Sporaconazole) erythromycin (Erythrocin, Ilosone, tse ling), phenytoin (Dilantin), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), le tse ling tse ngata.

Meriana e liehang ho koala mali (Anticoagulant / Antiplatelet drug)

Niacinamide e ka liehisa ho hoama ha mali. Ho nka niacinamide hammoho le meriana e fokotsang ho hoama e ka eketsa menyetla ea ho longoa le ho tsoa mali.

Meriana e meng e liehang ho koala mali e kenyelletsa aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), le tse ling.

Primidone (Mysoline)

Primidone (Mysoline) e robehile ke 'mele. Ho na le ngongoreho ea hore niacinamide e ka fokotseha hore na 'mele o senya primidone (Mysoline) kapele hakae. Empa ha ho na leseli le lekaneng ho tseba hore na sena se bohlokoa.

Litlama le litlatsetso tse ka lematsang sebete

Niacinamide e ka baka tšenyo ea sebete, haholo ha e sebelisoa ka litekanyetso tse phahameng. Ho nka niacinamide hammoho le litlama tse ling kapa litlatsetso tse ka lematsang sebete ho ka eketsa kotsi ena. Tse ling tsa lihlahisoa tsena li kenyelletsa androstenedione, lekhasi la borage, chaparral, comfrey, dehydroepiandrosterone (DHEA), germander, kava, oli ea pennyroyal, tomoso e khubelu le tse ling.

Litlama le litlatsetso tse ka liehang ho koala mali

Niacinamide e ka liehisa ho hoama ha mali. Ho sebelisa niacinamide hammoho le litlama tse ling le li-supplement tse fokotsang ho hoama ha mali ho ka eketsa menyetla ea ho tsoa mali ho batho ba bang. Litlama tse ling tsa mofuta ona li kenyelletsa angelica, clove, danshen, konofolo, ginger, Panax ginseng le tse ling.

Ha ho na litšebelisano tse tsebahalang le lijo.

Litekanyo tse latelang li ithutiloe lipatlisisong tsa mahlale:

BAHOLO

KA MOLOMO:

• Kakaretso: Lihlahisoa tse ling tsa tlatsetso ea lijo li kanna tsa se ke tsa thathamisa niacinamide ka thoko lebokoseng. Sebakeng seo, e kanna ea thathamisoa tlasa niacin. Niacin e lekantsoe ka li-niacin equivalents (NE). Tekanyo ea 1 mg ea niacinamide e ts'oana le 1 mg NE. Meputso ea lijo ea letsatsi le letsatsi e khothalletsoang (RDAs) bakeng sa niacinamide ho batho ba baholo ke 16 mg NE bakeng sa banna, 14 mg NE bakeng sa basali, 18 mg NE bakeng sa bakhachane, le 17 mg NE bakeng sa basali ba anyesang.
• Bakeng sa makhopho: Ho sebelisitsoe matlapa a nang le 750 mg ea niacinamide, 25 mg ea zinki, 1.5 mg ea koporo, le 500 mcg ea folic acid (Nicomide) hang kapa habeli ka letsatsi. Hape, matlapa a 1-4 a nang le niacinamide, azelaic acid, zinki, vithamine B6, koporo le folic acid (NicAzel, Elorac Inc., Vernon Hills, IL) li nkiloe letsatsi le letsatsi.
• Bakeng sa matšoao a khaello ea vithamine B3 joalo ka pellagra: 300-500 mg ka letsatsi ea niacinamide e fanoa ka litekanyo tse arotsoeng.
• Bakeng sa lefu la tsoekere: Niacinamide 1.2 dikgerama / m² (bokaholimo ba 'mele) kapa 25-50 mg / kg e sebelisoa letsatsi le leng le le leng bakeng sa ho fokotsa tsoelo-pele ea lefu la tsoekere la mofuta oa 1. Hape, ligrama tse 0,5 tsa niacinamide makhetlo a mararo ka letsatsi li sebelisoa ho fokotsa tsoelo-pele ea lefu la tsoekere la mofuta oa 2.
• Bakeng sa phosphate e phahameng maling (hyperphosphatemia): Niacinamide ho tloha ho 500 mg ho fihlela ho ligrama tse 1.75 ka letsatsi ka litekanyetso tse arotsoeng e sebelisoa bakeng sa libeke tse 8 ho isa ho tse 12.
• Bakeng sa mofetše oa larynx: 60 mg / kg ea niacinamide e fuoa lihora tse 1-1.5 pele ho hema carbogen (2% carbon dioxide le 98% oksijene) pele le nakong ea radiotherapy.
• Bakeng sa mofetše oa letlalo ntle le melanoma: 500 mg ea niacinamide hang kapa habeli ka letsatsi bakeng sa likhoeli tse 4-12.
• Bakeng sa ho phekola lefu la masapo a mabeli: 3 dikgerama tsa niacinamide ka letsatsi ka tekanyetso e arotsoeng libeke tse 12.

LEQHENG:

• Makhopho: Gel e nang le 4% niacinamide habeli ka letsatsi.

BANA

• Kakaretso: Meputso ea letsatsi le letsatsi ea lijo tse khothalletsoang (RDAs) bakeng sa niacinamide ho bana ke 2 mg bakeng sa masea a likhoeli tse 0-6, 4 mg NE bakeng sa masea a likhoeli tse 7-12, 6 mg NE bakeng sa bana ba lilemo li 1-3, 8 mg NE bakeng sa bana ba lilemo li 4-8, 12 mg NE bakeng sa bana ba lilemo li 9-13, 16 mg NE bakeng sa banna ba lilemo li 14-18, le 14 mg NE bakeng sa basali ba lilemo li 14-18.
• Bakeng sa makhopho: Ho bana bonyane ba lilemo li 12, matlapa a 1-4 a nang le niacinamide, azelaic acid, zinki, vithamine B6, koporo le folic acid (NicAzel, Elorac Inc., Vernon Hills, IL) a nooa letsatsi le letsatsi.
• Bakeng sa pellagra: 100-300 mg ea niacinamide e fuoa letsatsi le letsatsi ka litekanyo tse arotsoeng.
• Bakeng sa lefu la tsoekere la mofuta oa 1: 1.2 dikgerama / m² (bokaholimo ba 'mele) kapa 25-50 mg / kg ea niacinamide e sebelisoa letsatsi le leng le le leng bakeng sa ho fokotsa tsoelo-pele kapa ho thibela lefu la tsoekere la mofuta oa 1.

3-Pyridine Carboxamide, 3-Pyridinecarboxamide, Amide de l'Acide Nicotinique, B Complex Vitamin, Complexe de Vitamines B, Niacinamida, Nicamid, Nicosedine, Nicotinamide, Nicotinic Acid Amide, Nicotylamidum, Pyridine-3-carboxamide, Vitamin, Vitamin ya 3. , Vithamine B3.

Ho ithuta haholoanyane ka hore na sengoloa sena se ngotsoe joang, ka kopo bona Meriana ea Tlhahisoleseling e Akaretsang mokhoa.

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