Sengoli: William Ramirez
Letsatsi La Creation: 16 September 2021
Ntlafatsa Letsatsi: 1 November 2024
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What Doctors are saying about CBD? | Cannabidiol
Video: What Doctors are saying about CBD? | Cannabidiol

Litaba

Cannabidiol ke k'hemik'hale semeleng sa Cannabis sativa, e tsejoang hape e le matekoane kapa hemp. Lik'hemik'hale tse fetang 80, tse tsejoang e le li-cannabinoids, li fumanoe semeleng sa Cannabis sativa. Le ha delta-9-tetrahydrocannabinol (THC) e le sesebelisoa se ka sehloohong sa matekoane, cannabidiol e boetse e fumanoa ho tsoa ho hemp, e nang le li-THC tse nyane haholo.

Ho fetisoa ha Molao oa Temo oa Temo oa 2018 ho entse hore ho be molaong ho rekisa lihlahisoa tsa hemp le hemp ho la U.S. Empa seo ha se bolele hore lihlahisoa tsohle tsa cannabidiol tse tsoang ho hemp li molaong. Kaha cannabidiol e ithutiloe e le sethethefatsi se secha, e ke ke ea kenyelletsoa ka molao lijong kapa lijong tse tlatsetsang. Hape, cannabidiol e ke ke ea kenyelletsoa lihlahisoa tse rekisoang ka litlaleho tsa kalafo. Cannabidiol e ka kenyelletsoa feela lihlahisoa tsa "litlolo" mme ha feela e na le tlase ho 0,3% THC. Empa ho ntse ho na le lihlahisoa tse ngotsoeng e le li-supplement tsa lijo 'marakeng tse nang le cannabidiol. Palo ea cannabidiol e fumanehang lihlahisoa tsena ha e tlaleheloe ka nepo lebitsong la sehlahisoa.

Cannabidiol e sebelisoa haholo bakeng sa lefu la sethoathoa (lefu la sethoathoa). E boetse e sebelisetsoa ho tšoenyeha, bohloko, lefu la mesifa le bitsoang dystonia, lefu la Parkinson, lefu la Crohn le maemo a mang a mangata, empa ha ho na bopaki bo botle ba mahlale bo tšehetsang ts'ebeliso ena.

Meriana ea Tlhahisoleseling e Akaretsang e sebetsa hantle ho ipapisitsoe le bopaki ba mahlale ho latela sekala se latelang: E ​​ea sebetsa, e ka sebetsa hantle, mohlomong ea sebetsa, mohlomong e sa sebetse, mohlomong e sa sebetse, e sa sebetse ebile e sa lekana Bopaki bo lokelang ho lekanyetsoa.

Likarolo tsa katleho ea CANNABIDIOL (CBD) ke tse latelang:


E ka sebetsa hantle bakeng sa ...

  • Boloetse ba sethoathoa (lefu la sethoathoa). Sehlahisoa se ikhethileng sa cannabidiol (Epidiolex, GW Pharmaceuticals) se bonts'itsoe ho fokotsa ho oela ho batho ba baholo le bana ba nang le maemo a fapaneng a amanang le ho oela. Sehlahisoa sena ke setlhare se fanoang ke ngaka bakeng sa ho phekola sethoathoa se bakoang ke lefu la Dravet, lefu la Lennox-Gastaut, kapa lefu la methapo ea methapo. Ho boetse ho bontšitsoe ho fokotsa ho oela ho batho ba nang le lefu la Sturge-Weber, lefu le amanang le ts'oaetso ea lefu la sethoathoa (FIRES), le mathata a itseng a lefutso a bakang lefu la sethoathoa. Empa ha e amohelehe bakeng sa ho phekola mefuta ena e meng ea ho oa. Sehlahisoa sena hangata se nkoa se kopantsoe le meriana e tloahelehileng ea ho thibela ho nkela. Lihlahisoa tse ling tsa cannabidiol tse entsoeng ka labong le tsona li ntse li ithutoa bakeng sa lefu la sethoathoa. Empa lipatlisiso li na le moeli, 'me ha ho le e' ngoe ea lihlahisoa tsena e amoheloang e le lithethefatsi tsa ngaka.

Bopaki bo sa lekaneng ba ho lekanya katleho ea ...

  • Mofuta oa lefu la ho ruruha ha mala (lefu la Crohn). Phuputso ea pele e bonts'a hore ho nka cannabidiol ha ho fokotse ts'ebetso ea mafu ho batho ba baholo ba nang le lefu la Crohn.
  • Lefu la tsoekere. Phuputso ea pejana e bonts'a hore ho nka cannabidiol ha ho ntlafatse taolo ea tsoekere ea mali ho batho ba baholo ba nang le lefu la tsoekere la mofuta oa 2.
  • Boloetse ba ho sisinyeha bo tšoauoang ke liphapang tsa mesifa tse sa ithaopeng (dystonia). Ha ho hlake hore na cannabidiol e na le molemo bakeng sa dystonia.
  • Boemo bo futsitsoeng bo tšoauoang ke mathata a ho ithuta (fragile- X syndrome). Phuputso ea pejana e fana ka maikutlo a hore ho sebelisa gelidi ea cannabidiol ho ka fokotsa ho tšoenyeha le ho ntlafatsa boitšoaro ho bana ba nang le lefu la X le fokolang.
  • Boemo boo ho kenngoang ho hlaselang 'mele ho hlaselang' mele (graft-versus-host disease kapa GVHD). Boloetse ba maiketsetso ke bothata bo ka hlahang kamora ho kenella ha moko oa masapo. Patlisiso ea pele e fumane hore ho nka cannabidiol letsatsi le leng le le leng ho qala matsatsi a 7 pele ho kenyelletso ea moko oa masapo le ho tsoela pele matsatsi a 30 kamora ho kenya ho ka eketsa nako eo motho a e nkang ho hlahisa GVHD.
  • Boloetse ba boko bo futsitsoeng bo amang metsamao, maikutlo le menahano (Boloetse ba Huntington). Phuputso ea pele e bonts'a hore ho nka cannabidiol letsatsi le letsatsi ha ho ntlafatse matšoao a lefu la Huntington.
  • Multiple sclerosis (MS). Patlisiso ea pele e fana ka maikutlo a hore ho sebelisa spray ea cannabidiol tlasa leleme ho ka ntlafatsa bohloko le ho thatafala ha mesifa ho batho ba nang le MS.
  • Ho tlohela heroine, morphine, le lithethefatsi tse ling tsa opioid. Phuputso ea pele e bonts'a hore ho nka cannabidiol matsatsi a 3 ho ka fokotsa litakatso le matšoenyeho ho batho ba nang le ts'ebeliso ea ts'ebeliso ea heroine.
  • Lefu la Parkinson. Phuputso ea pele e bontša hore cannabidiol e ka fokotsa matšoenyeho le matšoao a kelello ho batho ba nang le lefu la Parkinson.
  • Boloetse ba kelello. Phuputso ea pejana e fana ka maikutlo a hore ho nka cannabidiol ho ntlafatsa matšoao le bophelo bo botle ho batho ba nang le schizophrenia.
  • Ho tlohela ho tsuba. Patlisiso ea pejana e fana ka maikutlo a hore ho hula cannabidiol ka inhaler ka beke e le 'ngoe ho ka fokotsa palo ea lisakerete tse tsubaang ke batho ba tsubang ba lekang ho khaotsa.
  • Mofuta oa matšoenyeho o tšoauoang ke ts'abo ho tse ling kapa maemong ohle a sechaba (lefu la khatello ea maikutlo sechabeng). Phuputso ea pele e bontša hore cannabidiol e ka ntlafatsa matšoenyeho ho batho ba nang le bothata bona. Empa ha ho hlake hore na e thusa ho fokotsa matšoenyeho nakong ea ho bua phatlalatsa.
  • Sehlopha sa maemo a bohloko a amang mohlahare le mesifa (mathata a temporomandibular kapa TMD). Phuputso ea pejana e bonts'a hore ho tlotsa oli e nang le cannabidiol letlalong ho ka fokotsa bohloko ho batho ba nang le TMD.
  • Tšenyo ea methapo matsohong le maotong (peripheral neuropathy).
  • Bothata ba ho ferekana kelellong.
  • Ho hlobaela.
  • Maemo a mang.
Bopaki bo bongata boa hlokahala ho lekola katleho ea cannabidiol bakeng sa ts'ebeliso ena.

Cannabidiol e na le litlamorao bokong. Ha ho hlake hore na hantle-ntle sesosa sa litlamorao tsena ke eng. Leha ho le joalo, cannabidiol e bonahala e thibela ho senyeha ha k'hemik'hale bokong e amang bohloko, maikutlo le ts'ebetso ea kelello. Ho thibela ho senyeha ha k'hemik'hale ena le ho eketsa maemo a eona maling ho bonahala ho fokotsa matšoao a kelello a amanang le maemo a kang schizophrenia. Cannabidiol e kanna ea thibela tse ling tsa litlamorao tsa kelello tsa delta-9-tetrahydrocannabinol (THC). Hape, cannabidiol e bonahala e fokotsa bohloko le matšoenyeho.

Ha e nkoa ka molomo: Cannabidiol ke MOTS'ELISI TS'IU ha e nooa ka molomo kapa e fafatsoa ka tlasa leleme ka nepo. Cannabidiol ka litekanyetso tsa ho fihlela ho 300 mg letsatsi le leng le le leng e nkiloe ka molomo e sireletsehile ho fihlela likhoeli tse 6. Litekanyetso tse phahameng tsa 1200-1500 mg letsatsi le leng le le leng li nkuoe ka molomo li bolokehile ho fihlela libeke tse 4. Sehlahisoa sa ngaka sa cannabidiol (Epidiolex) se lumelloa hore se nooe ka molomo ka litekanyetso tse ka bang 25 mg / kg ka letsatsi. Li-spray tsa Cannabidiol tse sebelisitsoeng tlasa leleme li sebelisitsoe ka tekanyetso ea 2.5 mg ho fihlela libeke tse 2.

Tse ling tsa litla-morao tsa cannabidiol li kenyelletsa molomo o omileng, khatello e tlase ea mali, hlooho e bobebe le ho otsela. Matšoao a kotsi ea sebete le 'ona a tlalehiloe ho bakuli ba bang, empa sena ha se tloaelehileng haholo.

Ha e sebelisoa letlalong: Ha ho na tlhaiso-leseling e lekaneng e ka tšeptjoang ea ho tseba hore na cannabidiol e bolokehile kapa hore na litlamorao e ka ba life.

Litlhokomelo le litemoso tse khethehileng:

Bokhachane le ho anyesa: Cannabidiol ke MONYETSI O SA SIRELEKE ho sebedisa ha o le moimana kapa o anyesa. Lihlahisoa tsa Cannabidiol li ka silafatsoa ke lisebelisoa tse ling tse ka bang kotsi ho lesea kapa lesea. Lula ka lehlakoreng le sireletsehileng 'me u qobe tšebeliso.

Bana: Sehlahisoa sa ngaka sa cannabidiol (Epidiolex) ke MOTS'ELISI TS'IU ha e nooa ka molomo ka litekanyetso ho fihlela ho 25 mg / kg ka letsatsi. Sehlahisoa sena se lumelletsoe ho sebelisoa ho bana ba itseng ba lilemo li 1 ho ea holimo.

Lefu la sebete: Batho ba nang le lefu la sebete ba kanna ba hloka ho sebelisa tekanyetso e tlase ea cannabidiol ha e bapisoa le bakuli ba phetseng hantle.

Lefu la Parkinson: Liphuputso tse ling tsa pejana li fana ka maikutlo a hore ho noa li-cannabidiol tse ngata ho ka etsa hore mesifa e sisinyehe le ho thothomela ho hobe ho batho ba bang ba nang le lefu la Parkinson.

E itekanetse
E-ba hlokolosi ka motsoako ona.
Brivaracetam (Briviact)
Brivaracetam e fetotsoe le ho robeha ke 'mele. Cannabidiol e ka fokotsa hore na 'mele o senya brivaracetam kapele hakae. Sena se ka eketsa maemo a brivaracetam 'meleng.
Carbamazepine (Tegretol)
Carbamazepine e fetotsoe ebe e robeha ke 'mele. Cannabidiol e ka fokotsa hore na 'mele o senya carbamazepine kapele hakae. Sena se ka eketsa maemo a carbamazepine 'meleng le ho eketsa litlamorao.
Clobazam (Onfi)
Clobazam e fetotsoe mme e robeha ke sebete. Cannabidiol e ka fokotsa hore na sebete se senya kapele hakae clobazam. Sena se ka eketsa litlamorao le litla-morao tsa clobazam.
Eslicarbazepine (Aptiom)
Eslicarbazepine e fetoloa ebe e robeha ke 'mele. Cannabidiol e ka fokotsa hore na 'mele o senya eslicarbazepine kapele hakae. Sena se ka eketsa maemo a eslicarbazepine 'meleng ka palo e nyane.
Everolimus (Zostress)
Everolimus e fetotsoe mme e robehile ke 'mele. Cannabidiol e ka fokotseha hore na 'mele o senya li-everolimus kapele hakae. Sena se ka eketsa maemo a everolimus 'meleng.
Lithium
Ho nka litekanyetso tse phahameng tsa cannabidiol ho ka eketsa maemo a lithium. Sena se ka eketsa kotsi ea lithium toxicity.
Meriana e fetotsoeng ke sebete (likaroloana tsa Cytochrome P450 1A1 (CYP1A1))
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ka khopolo, ho sebelisa cannabidiol hammoho le meriana e robehileng ke sebete ho ka eketsa litlamorao le litlamorao tsa meriana e meng. Pele o sebelisa cannabidiol, bua le mofani oa tlhokomelo ea bophelo haeba u noa meriana e fetotsoeng ke sebete.

Meriana e meng e fetotsoeng ke sebete e kenyelletsa chlorzoxazone (Lorzone) le theophylline (Theo-Dur, tse ling).
Meriana e fetotsoeng ke sebete (likaroloana tsa Cytochrome P450 1A2 (CYP1A2))
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ka khopolo, ho sebelisa cannabidiol hammoho le meriana e robehileng ke sebete ho ka eketsa litlamorao le litlamorao tsa meriana e meng. Pele o sebelisa cannabidiol, bua le mofani oa tlhokomelo ea bophelo haeba u noa meriana e fetotsoeng ke sebete.

Meriana e meng e fetotsoeng ke sebete e kenyelletsa amitriptyline (Elavil), haloperidol (Haldol), ondansetron (Zofran), propranolol (Inderal), theophylline (Theo-Dur, tse ling), verapamil (Calan, Isoptin, tse ling), le tse ling.
Meriana e fetotsoeng ke sebete (likaroloana tsa Cytochrome P450 1B1 (CYP1B1))
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ka khopolo, ho sebelisa cannabidiol hammoho le meriana e meng e robehileng ke sebete ho ka eketsa litlamorao le litlamorao tsa meriana e meng. Pele o sebelisa cannabidiol, bua le mofani oa tlhokomelo ea bophelo haeba u noa meriana e fetotsoeng ke sebete.

Meriana e meng e fetotsoeng ke sebete e kenyelletsa theophylline (Theo-Dur, tse ling), omeprazole (Prilosec, Omesec), clozapine (Clozaril, FazaClo), progesterone (Prometrium, tse ling), lansoprazole (Prevacid), flutamide (Eulexin), oxaliplatin (Eloxatin ), erlotinib (Tarceva), le caffeine.
Meriana e fetotsoe ke sebete (likaroloana tsa Cytochrome P450 2A6 (CYP2A6))
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ka khopolo, ho sebelisa cannabidiol hammoho le meriana e robehileng ke sebete ho ka eketsa litlamorao le litlamorao tsa meriana e meng. Pele o sebelisa cannabidiol, bua le mofani oa tlhokomelo ea bophelo haeba u noa meriana e fetotsoeng ke sebete.

Meriana e meng e fetotsoeng ke sebete e kenyelletsa nicotine, chlormethiazole (Heminevrin), coumarin, methoxyflurane (Penthrox), halothane (Fluothane), valproic acid (Depacon), disulfiram (Antabuse), le tse ling.
Meriana e fetotsoeng ke sebete (likaroloana tsa Cytochrome P450 2B6 (CYP2B6))
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ka khopolo, ho sebelisa cannabidiol hammoho le meriana e meng e robehileng ke sebete ho ka eketsa litlamorao le litlamorao tsa meriana e meng. Pele o sebelisa cannabidiol, bua le mofani oa tlhokomelo ea bophelo haeba u noa meriana e fetotsoeng ke sebete.

Meriana e meng e fetotsoeng ke sebete e kenyelletsa ketamine (Ketalar), phenobarbital, orphenadrine (Norflex), secobarbital (Seconal), le dexamethasone (Decadron).
Meriana e fetotsoeng ke sebete (likaroloana tsa Cytochrome P450 2C19 (CYP2C19))
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ka khopolo, ho sebelisa cannabidiol hammoho le meriana e meng e robehileng ke sebete ho ka eketsa litlamorao le litlamorao tsa meriana e meng. Pele o sebelisa cannabidiol, bua le mofani oa tlhokomelo ea bophelo haeba u noa meriana e fetotsoeng ke sebete.

Meriana e meng e fetotsoeng ke sebete e kenyelletsa proton pump inhibitors ho kenyelletsa omeprazole (Prilosec), lansoprazole (Prevacid), le pantoprazole (Protonix); diazepam (Valium); carisoprodol (Soma); nelfinavir (Viracept); le ba bang.
Meriana e fetotsoeng ke sebete (likaroloana tsa Cytochrome P450 2C8 (CYP2C8))
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ka khopolo, ho sebelisa cannabidiol hammoho le meriana e robehileng ke sebete ho ka eketsa litlamorao le litlamorao tsa meriana e meng. Pele o sebelisa cannabidiol, bua le mofani oa tlhokomelo ea bophelo haeba u noa meriana e fetotsoeng ke sebete.
Meriana e meng e fetotsoeng ke sebete e kenyelletsa amiodarone (Cordarone), carbamazepine (Tegretol), chloroquine (Aralen), diclofenac (Voltaren), paclitaxel (Taxol), repaglinide (Prandin) le tse ling.
Meriana e fetotsoeng ke sebete (likaroloana tsa Cytochrome P450 2C9 (CYP2C9))
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ka khopolo, ho sebelisa cannabidiol hammoho le meriana e meng e robehileng ke sebete ho ka eketsa litlamorao le litlamorao tsa meriana e meng. Pele o sebelisa cannabidiol, bua le mofani oa tlhokomelo ea bophelo haeba u noa meriana e fetotsoeng ke sebete.

Meriana e meng e fetotsoeng ke sebete e kenyelletsa li-anti-inflammatory drug (NSAID) tse kang diclofenac (Cataflam, Voltaren), ibuprofen (Motrin), meloxicam (Mobic), piroxicam (Feldene), le celecoxib (Celebrex); amitriptyline (Elavil); warfarin (Coumadin); glipizide (Glucotrol); losartan (Cozaar); le ba bang.
Meriana e fetotsoeng ke sebete (likaroloana tsa Cytochrome P450 2D6 (CYP2D6))
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ka khopolo, ho sebelisa cannabidiol hammoho le meriana e robehileng ke sebete ho ka eketsa litlamorao le litlamorao tsa meriana e meng. Pele o sebelisa cannabidiol, bua le mofani oa tlhokomelo ea bophelo haeba u noa meriana e fetotsoeng ke sebete.

Meriana e meng e fetotsoeng ke sebete e kenyelletsa amitriptyline (Elavil), codeine, desipramine (Norpramin), flecainide (Tambocor), haloperidol (Haldol), imipramine (Tofranil), metoprolol (Lopressor, Toprol XL), ondansetron (Zofran), paroxetine (Paxiletine) ), risperidone (Risperdal), tramadol (Ultram), venlafaxine (Effexor), le tse ling.
Meriana e fetotsoeng ke sebete (likaroloana tsa Cytochrome P450 3A4 (CYP3A4))
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ka khopolo, ho sebelisa cannabidiol hammoho le meriana e meng e robehileng ke sebete ho ka eketsa litlamorao le litlamorao tsa meriana e meng. Pele o sebelisa cannabidiol, bua le mofani oa tlhokomelo ea bophelo haeba u noa meriana e fetotsoeng ke sebete.

Meriana e meng e fetotsoeng ke sebete e kenyelletsa alprazolam (Xanax), amlodipine (Norvasc), clarithromycin (Biaxin), cyclosporine (Sandimmune), erythromycin, lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Halcion), verapamil (Calan, Isoptin) le ba bang ba bangata.
Meriana e fetotsoeng ke sebete (likaroloana tsa Cytochrome P450 3A5 (CYP3A5))
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ka khopolo, ho sebelisa cannabidiol hammoho le meriana e meng e robehileng ke sebete ho ka eketsa litlamorao le litlamorao tsa meriana e meng. Pele o sebelisa cannabidiol, bua le mofani oa tlhokomelo ea bophelo haeba u noa meriana e fetotsoeng ke sebete.

Meriana e meng e fetotsoeng ke sebete e kenyelletsa testosterone, progesterone (Endometrin, Prometrium), nifedipine (Adalat CC, Procardia XL), cyclosporine (Sandimmune), le tse ling.
Meriana e fetotsoeng ke sebete (Lithethefatsi tse nang le litlolo tse matlafatsang)
Meriana e meng ea fetoloa ebe ea robeha sebeteng. Cannabidiol e ka fokotsa hore na sebete se senya meriana kapele hakae. Ho nka cannabidiol hammoho le meriana e robehileng ke sebete ho ka eketsa litlamorao le litla-morao tsa meriana ena.
E meng ea meriana e fetotsoeng ke sebete e kenyelletsa acetaminophen (Tylenol, tse ling) le oxazepam (Serax), haloperidol (Haldol), lamotrigine (Lamictal), morphine (MS Contin, Roxanol), zidovudine (AZT, Retrovir), le tse ling.
Meriana e fokotsang ho senyeha ha meriana e meng ke sebete (Cytochrome P450 2C19 (CYP2C19) inhibitors)
Cannabidiol e robehile ke sebete. Meriana e meng e ka fokotsa hore na sebete se senya kapele hakae cannabidiol. Ho nka cannabidiol hammoho le meriana ena ho ka eketsa litlamorao le litla-morao tsa cannabidiol.
Meriana e meng e ka fokotsang ho senyeha ha cannabidiol sebeteng e kenyelletsa cimetidine (Tagamet), fluvoxamine (Luvox), omeprazole (Prilosec); ticlopidine (Ticlid), topiramate (Topamax), le tse ling.
Meriana e fokotsang ho senyeha ha meriana e meng sebeteng (Cytochrome P450 3A4 (CYP3A4) inhibitors)
Cannabidiol e robehile ke sebete. Meriana e meng e ka fokotsa hore na sebete se senya kapele hakae cannabidiol. Ho nka cannabidiol hammoho le meriana ena ho ka eketsa litlamorao le litla-morao tsa cannabidiol.
Meriana e meng e ka fokotsang hore na sebete se robeha kapele hakae cannabidiol e kenyelletsa amiodarone (Cordarone), clarithromycin (Biaxin), diltiazem (Cardizem), erythromycin (E-mycin, Erythrocin), indinavir (Crixivan), ritonavir (Norvir), saquinavir (Fortovase) , Invirase), le ba bang ba bangata.
Meriana e eketsang ho senyeha ha meriana e meng ke sebete (Cytochrome P450 3A4 (CYP3A4) inducers)
Cannabidiol e robehile ke sebete. Meriana e meng e ka eketsa hore na sebete se senya kapele joang cannabidiol. Ho nka cannabidiol hammoho le meriana ena ho ka fokotsa litlamorao tsa cannabidiol.
E meng ea meriana ena e kenyelletsa carbamazepine (Tegretol), phenobarbital, phenytoin (Dilantin), rifampin, rifabutin (Mycobutin), le tse ling.
Meriana e eketsang ho senyeha ha meriana e meng ke sebete (Cytochrome P450 2C19 (CYP2C19) inducers)
Cannabidiol e robehile ke sebete. Meriana e meng e ka eketsa hore na sebete se senya kapele joang cannabidiol. Ho nka cannabidiol hammoho le meriana ena ho ka fokotsa litlamorao tsa cannabidiol.
Meriana e meng e ka eketsang ho senyeha ha cannabidiol sebeteng e kenyelletsa carbamazepine (Tegretol), prednisone (Deltasone), le rifampin (Rifadin, Rimactane).
Methadone (Dolophine)
Methadone e robehile ke sebete. Cannabidiol e ka fokotsa hore na sebete se senya methadone kapele hakae. Ho nka cannabidiol hammoho le methadone ho ka eketsa litlamorao le litla-morao tsa methadone.
Rufinamide (Banzel)
Rufinamide e fetotsoe le ho robeha ke 'mele. Cannabidiol e ka fokotsa hore na 'mele o senya rufinamide kapele hakae. Sena se ka eketsa maemo a rufinamide 'meleng ka chelete e nyane.
Meriana e thetsang (CNS depressants)
Cannabidiol e ka baka boroko le ho otsela. Meriana e bakang boroko e bitsoa litlhare. Ho nka cannabidiol hammoho le meriana e kokobetsang maikutlo ho ka baka boroko haholo.

Meriana e meng ea thobalano e kenyelletsa benzodiazepines, pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), thiopental (Pentothal), fentanyl (Duragesic, Sublimaze), morphine, propofol (Diprivan) le tse ling.
Sirolimus (Rapamune)
Sirolimus e fetotsoe le ho robeha ke 'mele. Cannabidiol e ka fokotsa hore na 'mele o senya sirolimus kapele hakae. Sena se ka eketsa maemo a sirolimus 'meleng.
Stiripentol (Diacomit)
Stiripentol e fetotsoe 'me e robehile ke' mele. Cannabidiol e ka 'na ea fokotsa hore na' mele o senya kapele hakae stiripentol. Sena se ka eketsa maemo a stiripentol 'meleng le ho eketsa litlamorao.
Tacrolimus (Prograf)
Tacrolimus e fetotsoe le ho robeha ke 'mele. Cannabidiol e ka fokotsa hore na 'mele o senya tacrolimus kapele hakae. Sena se ka eketsa maemo a tacrolimus 'meleng.
Topiramate (Tompamax)
Topiramate e fetoloa mme e robeha ke 'mele. Cannabidiol e ka fokotsa hore na 'mele o senya topiramate kapele hakae. Sena se ka eketsa maemo a topiramate 'meleng ka palo e nyane.
Tlanya
Valproic acid e ka baka kotsi ea sebete. Ho nka cannabidiol ka valproic acid ho ka eketsa menyetla ea ho tsoa likotsi sebeteng. Cannabidiol le / kapa acid ea valproic e kanna ea hloka ho emisoa, kapa lethal dose le kanna la hloka ho fokotsoa.
Warfarin
Cannabidiol e ka eketsa maemo a warfarin, a ka eketsang menyetla ea ho tsoa mali. Cannabidiol le / kapa warfarin li kanna tsa hloka ho emisoa, kapa lethal dose le kanna la hloka ho fokotsoa.
Zonisamide
Zonisamide e fetoloa le ho robeha ke 'mele. Cannabidiol e ka fokotsa hore na 'mele o senya zonisamide kapele hakae. Sena se ka eketsa maemo a zonisamide 'meleng ka chelete e nyane.
Litlama le litlatsetso tse nang le thepa ea ho qhekella
Cannabidiol e ka baka boroko kapa ho otsela. Ho e sebelisa hammoho le litlama tse ling le li-supplement tse nang le phello e tšoanang ho ka baka boroko bo boholo. Tse ling tsa litlama tsena le li-supplement li kenyelletsa calamus, California poppy, catnip, hop, Jamaican dogwood, kava, L-tryptophan, melatonin, sage, SAMe, wort ea St. John, sassafras, skullcap, le tse ling.
Joala (Ethanol)
Ho nka cannabidiol ka joala ho eketsa palo ea cannabidiol e kenang 'meleng. Sena se ka eketsa litlamorao le litla-morao tsa cannabidiol.
Mafura le lijo tse nang le mafura
Ho nka cannabidiol ka lijo tse nang le mafura a mangata kapa bonyane ho na le mafura, ho eketsa palo ea cannabidiol e kenang 'meleng. Sena se ka eketsa litlamorao le litla-morao tsa cannabidiol.
Lebese
Ho nka cannabidiol ka lebese ho eketsa palo ea cannabidiol e kenang 'meleng. Sena se ka eketsa litlamorao le litla-morao tsa cannabidiol.
Litekanyo tse latelang li ithutiloe lipatlisisong tsa mahlale:

BAHOLO

KA MOLOMO:
  • Bakeng sa lefu la sethoathoa: Ho sebelisitsoe sehlahisoa sa moriana oa cannabidiol (Epidiolex). Tekanyo e khothalletsoang ea ho qala lefu la Lennox-Gastaut le lefu la Dravet ke 2.5 mg / kg habeli ka letsatsi (5 mg / kg / ka letsatsi). Kamora beke e le 'ngoe lethal dose e ka nyolohela ho 5 mg / kg habeli ka letsatsi (10 mg / kg / ka letsatsi). Haeba motho a sa arabele tekong ena, boholo bo khothalletsoang ke 10 mg / kg habeli ka letsatsi (20 mg / kg / ka letsatsi). Tekanyo e khothalelitsoeng ea ho qala lefuba la scerosis ke 2.5 mg / kg habeli ka letsatsi (5 mg / kg / ka letsatsi). Sena se ka eketsoa nako le nako ha ho hlokahala, ho fihlela ho 12.5 mg / kg habeli ka letsatsi (25 mg / kg / ka letsatsi). Ha ho na bopaki bo matla ba mahlale a hore lihlahisoa tse sa ngolisoeng tsa cannabidiol li molemo bakeng sa lefu la sethoathoa.
BANA

KA MOLOMO:
  • Bakeng sa lefu la sethoathoa: Ho sebelisitsoe sehlahisoa sa moriana oa cannabidiol (Epidiolex). Tekanyo e khothalelitsoeng ea ho qala lefu la Lennox-Gastaut le lefu la Dravet ke 2.5 mg / kg habeli ka letsatsi (5 mg / kg / ka letsatsi). Kamora beke e le 'ngoe lethal dose e ka nyolohela ho 5 mg / kg habeli ka letsatsi (10 mg / kg / ka letsatsi). Haeba motho a sa arabele tekong ena, boholo bo khothalletsoang ke 10 mg / kg habeli ka letsatsi (20 mg / kg / ka letsatsi). Tekanyo e khothalelitsoeng ea ho qala lefuba la scerosis ke 2.5 mg / kg habeli ka letsatsi (5 mg / kg / ka letsatsi). Sena se ka eketsoa nako le nako ha ho hlokahala, ho fihlela ho 12.5 mg / kg habeli ka letsatsi (25 mg / kg / ka letsatsi). Ha ho na bopaki bo matla ba mahlale a hore lihlahisoa tse sa ngolisoeng tsa cannabidiol li molemo bakeng sa lefu la sethoathoa.
2 - [(1R, 6R) -3-Methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl] -5-pentylbenzene-1,3-diol, CBD.

Ho ithuta haholoanyane ka hore na sengoloa sena se ngotsoe joang, ka kopo bona Meriana ea Tlhahisoleseling e Akaretsang mokhoa.


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