Phekolo ea thrombolytic

Phekolo ea Thrombolytic ke ts'ebeliso ea lithethefatsi ho qhaqha kapa ho qhala mali, e leng sesosa se ka sehloohong sa litlhaselo tsa pelo le stroke.

Meriana ea Thrombolytic e amoheloa bakeng sa kalafo ea tšohanyetso ea stroke le lefu la pelo. Moriana o sebelisoang haholo bakeng sa kalafo ea thrombolytic ke dinama tse nyenyane tsa plasminogen activator (tPA), empa lithethefatsi tse ling li ka etsa se tšoanang.

Ka nepo, o lokela ho fumana meriana ea thrombolytic nakong ea metsotso e 30 ea pele kamora ho fihla sepetlele bakeng sa kalafo.

HLASOA PELO

Lefu la mali le ka thiba methapo ea pelo. Sena se ka baka lefu la pelo, ha karolo e 'ngoe ea mesifa ea pelo e shoa ka lebaka la khaello ea oksijene e tlisoang ke mali.

Thrombolytics e sebetsa ka ho qhala seaparo se seholo kapele. Sena se thusa ho qala phallo ea mali ho ea fihla pelong mme se thusa ho thibela tšenyo ea mesifa ea pelo. Thrombolytics e ka emisa lefu la pelo le neng le ka ba le leholo ho feta kapa le ka bolaeang. Liphetho li betere ha o fumana sethethefatsi sa thrombolytic nakong ea lihora tse 12 kamora hore lefu la pelo le qale. Empa ha kalafo e qala kapele, litholoana li ba betere.

Lithethefatsi li khutlisetsa phallo ea mali maling a batho ba bangata. Leha ho le joalo, phallo ea mali e kanna ea se sebetse hantle ka botlalo mme ho ntse ho ka ba le mesifa e fokolang e senyehileng. Ho ka hlokahala kalafo e ngoe, joalo ka catheterization ea pelo le angioplasty le stenting.

Mofani oa hao oa tlhokomelo ea bophelo o tla theha liqeto mabapi le hore na o tla u fa moriana oa thrombolytic bakeng sa lefu la pelo maemong a mangata. Lintlha tsena li kenyelletsa nalane ea hau ea bohloko ba sefuba le sephetho sa tlhahlobo ea ECG.

Lintlha tse ling tse sebelisitsoeng ho tseba hore na u moemeli ea hantle oa thrombolytics li kenyelletsa:

• Lilemo (batho ba baholo ba kotsing e kholo ea mathata)
• Thobalano
• Nalane ea bongaka (ho kenyelletsa nalane ea hau ea tlhaselo ea pelo e fetileng, lefu la tsoekere, khatello e tlase ea mali, kapa ho eketseha ha sekhahla sa pelo)

Ka kakaretso, thrombolytics e kanna ea se fuoe haeba u na le:

• Kotsi ea morao tjena ea hlooho
• Mathata a ho tsoa mali
• Liso tsa mali
• Boimana
• Ho buuoa haufinyane
• E nkile meriana e fokotsang mali joalo ka Coumadin
• Tsietsi
• Khatello ea mali e sa laoleheng (e matla)

LIEKETSO

Maqeba a mangata a bakoa ke ha maqeba a mali a ea methapong ea mali bokong 'me a thiba phallo ea mali sebakeng seo. Bakeng sa liropo tse joalo (lischemic stroke), thrombolytics e ka sebelisoa ho thusa ho qhala seaparo kapele. Ho fana ka thrombolytics nakong ea lihora tse 3 tsa matšoao a pele a stroke ho ka thusa ho fokotsa tšenyo ea seterouku le bokooa.

Qeto ea ho fana ka lithethefatsi e ipapisitse le:

• Tlhatlhobo ea boko ea CT ho etsa bonnete ba hore ha ho na mali a tsoang
• Tlhahlobo ea 'mele e bonts'ang stroke e kholo
• Nalane ea hau ea bongaka

Joalo ka litlhaselo tsa pelo, sethethefatsi se qhibilihisang leqhoa ha se hangata se fanoang haeba u na le a mang a mathata a mang a bongaka a thathamisitsoeng kaholimo.

Thrombolytics ha e fuoe motho ea nang le stroke e amanang le ho tsoa mali bokong. Li ka mpefatsa seterouku ka ho baka ho tsoa mali ho eketsehileng.

LIKOTSI

Ho tsoa mali ke kotsi e tloaelehileng haholo. E ka beha bophelo kotsing.

Ho tsoa mali hanyane ho tsoa mareneneng kapa linkong ho ka hlaha ho batho ba ka bang 25% ba fumanang sethethefatsi. Ho tsoa mali bokong ho etsahala hoo e ka bang 1% ea nako. Kotsi ena e ts'oana le bakuli ba stroke le ba pelo.

Haeba thrombolytics e utloahala e le kotsi haholo, mefuta e meng ea kalafo ea maqeba a bakang stroke kapa lefu la pelo e kenyelletsa:

• Ho tlosoa ha clot (thrombectomy)
• Mokhoa oa ho bula methapo ea mali e patisaneng kapa e koetsoeng e fanang ka mali pelong kapa bokong

Ikopanye le mofani oa tlhokomelo ea bophelo bo botle kapa mohala 911

Ho hlaseloa ke pelo le lichapo ke maemo a tšohanyetso a bongaka. Kalafo ea kapele ea thrombolytics e qala, e ba le monyetla o motle oa ho ba le sephetho se setle.

Lisebelisuoa tsa plasminogen; TPA; Alteplase; Pheta; Tenecteplase; Activase thrombolytic moemeli; Mahlahana a qhibilihang a Clot; Phekolo ea phetisetso; Leqeba - thrombolytic; Lefu la pelo - thrombolytic; Embolism e bohloko - thrombolytic; Thrombosis - thrombolytic; Lanoteplase; Staphylokinase; Streptokinase (SK); Urokinase; Leqeba - thrombolytic phekolo; Lefu la pelo - thrombolytic therapy; Leqeba - thrombolysis; Lefu la pelo - thrombolysis; Myocardial infarction - thrombolysis

• Leqeba
• Thrombus
• Lits'oants'o tsa `` EC '' tsa myocardial infarction

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Crocco TJ, Meurer WJ. Leqeba. Ka: Marako RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Likhopolo le Tloaelo ea Kliniki. La 9th. Philadelphia, PA: Elsevier; 2018: khaolo ea 91.

Jaffer IH, Weitz JI. Lithethefatsi tsa Antithrombotic. Ka: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Melao-motheo le Tloaelo ea Motheo. La 7th. Philadelphia, PA: Elsevier; 2018: khaolo ea 149.

O'Gara PT, Kushner FG, Ascheim DD, le al. Tataiso ea 2013 ACCF / AHA bakeng sa taolo ea infarction ea ST-elevation myocardial infarction: tlaleho ea American College of Cardiology Foundation / American Heart Association Task Force on Practice Guidelines. Tsamaiso. 2013; 127 (4): 529-555. PMID: 23247303 e fetotsoe.ncbi.nlm.nih.gov/23247303/.