Teko ea antigen ea ho se lumellane

Teko ea mali ea antiocompatibility antigen e sheba liprotheine tse bitsoang li-antigen leukocyte antigen (HLAs). Tsena li fumanoa holim 'a lisele tsohle tsa' mele oa motho. Li-HLA li fumanoa ka bongata holim'a lisele tse tšoeu tsa mali. Li thusa sesole sa 'mele ho tseba phapang lipakeng tsa lisele tsa' mele le lintho tse sa tsoeng 'meleng oa hau.

Mali a ntšoa mothapong. U ka utloa bohloko bo bonyenyane kapa motsu ha nale e kentsoe. Kamora moo, ho kanna ha ba le ho tsitsipana.

Ha ho hlokahale hore u itokisetse tlhahlobo ena.

Liphetho tsa tlhahlobo ena li ka sebelisoa ho khetholla lipapaling tse ntle bakeng sa mahlahahlaha a lisele le li-transplants tsa setho. Tsena li ka kenyelletsa ho kenyelletsa liphio kapa ho kenyelletsa 'moko oa masapo.

E kanna ea sebelisoa ho:

• Hlahloba mathata a itseng a ho itšireletsa mafung. Hypersensitivity e bakoang ke lithethefatsi ke mohlala.
• Fumana likamano lipakeng tsa bana le batsoali ha likamano tse joalo li botsoa.
• Lekola kalafo ka meriana e meng.

U na le lihlopha tse nyane tsa li-HLA tse fetisitsoeng ke batsoali ba hau. Bana, ka karolelano, ba tla ba le halofo ea li-HLA tsa bona tse tšoanang le halofo ea bo-mme le halofo ea li-HLA tsa bona tse tšoanang le halofo ea ntate oa bona.

Ha ho na monyetla oa hore batho ba babeli ba sa amaneng le bona ba be le litlolo tse tšoanang tsa HLA. Leha ho le joalo, mafahla a tšoanang a ka tšoana.

Mefuta e meng ea HLA e atile haholo ho mafu a itseng a itšireletsang mafung. Ka mohlala, antigen ea HLA-B27 e fumanoa ho batho ba bangata (empa eseng kaofela) ba nang le ankylosing spondylitis le Reiter syndrome.

Ha ho na kotsi e kholo ea ho nkuoa mali a hau. Methapo le methapo li fapana ka boholo ho tloha ho motho e mong ho ea ho o mong le ho tloha lehlakoreng le leng la 'mele ho ea ho le leng. Ho nka mali ho batho ba bang ho ka ba thata ho feta ho ba bang.

Likotsi tse ling tse amanang le ho huloa mali li nyane, empa li ka kenyelletsa:

• Ho akheha kapa ho ikutloa o le hlooho e boima
• Li-punctures tse ngata ho fumana methapo
• Hematoma (mali a hahiloeng ka tlas'a letlalo)
• Ho tsoa mali a mangata
• Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

Ho ngola HLA; Ho ngola ka linama

• Teko ea mali
• Lisele tsa masapo

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Monos DS, Winchester RJ. Rarahanyo e kholo ea nalane ea nalane ea eona. Ho: Rich RR, Fleisher TA, Shearer WT, Schroeder HW, Ba fokolang AJ, Weyand CM, eds. Clinical Immunology: Melao-motheo le Tloaelo. La 5th. Philadelphia, PA: Elsevier; 2019: khaolo ea 5.

Wang E, Adams S, Stroncek DF, Marincola FM. Antigen leukocyte antigen ea motho le litsamaiso tsa antigen tsa motho tsa neutrophil. Ka: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Melao-motheo le Tloaelo ea Motheo. La 7th. Philadelphia, PA: Elsevier; 2018: khaolo ea 113.