Immunoelectrophoresis - mali

Serum immunoelectrophoresis ke teko ea laborateng e lekanyang liprotheine tse bitsoang immunoglobulins maling. Li-immunoglobulin ke liprotheine tse sebetsang e le lithibela-mafu, tse loantšang tšoaetso. Hona le mefuta e mengata ea li-immunoglobulin tse loantšang mefuta e fapaneng ea tšoaetso. Li-immunoglobulin tse ling li ka ba tse sa tloaelehang 'me e ka ba ka lebaka la mofetše.

Li-immunoglobulin le tsona li ka lekanyetsoa ka morong.

Ho hlokahala sampole ea mali.

Ha ho na litokisetso tse khethehileng bakeng sa teko ena.

Ha nale e kentsoe ho hula mali, batho ba bang ba utloa bohloko bo itekanetseng. Ba bang ba ikutloa feela ho hlaba kapa ho hlaba. Kamora moo, ho kanna ha ba le ho longoa kapa ho longoa hanyenyane. Haufinyane sena sea fela.

Teko ena hangata e sebelisoa ho lekola maemo a lithibela-mafu ha mefuta e meng ea mofetše le mathata a mang a le teng kapa a belaelloa.

Sephetho se tloaelehileng (se fosahetseng) se bolela hore sampole ea mali e na le mefuta e tloaelehileng ea li-immunoglobulin. Boemo ba immunoglobulin e le 'ngoe bo ne bo sa phahama ho feta eng kapa eng.

Liphetho tse sa tloaelehang li ka bakoa ke:

• Multiple myeloma (mofuta oa mofets'e oa mali)
• Lefuemia e sa foleng ea lymphocytic kapa Waldenström macroglobulinemia (mefuta ea kankere e tšoeu ea lisele tsa mali)
• Amyloidosis (liprotheine tse sa tloaelehang tsa lisele le litho)
• Lymphoma (kankere ea lisele tsa lymph)
• Ho hloleha ha liphio
• Tšoaetso

Batho ba bang ba na le li-immunoglobulin tse monoclonal, empa ha ba na mofetše. Sena se bitsoa monoclonal gammopathy ea bohlokoa bo sa tsejoeng, kapa MGUS.

Ha ho na kotsi e kholo ea ho nkuoa mali a hau. Methapo le methapo li fapana ka boholo ho tloha ho motho e mong ho ea ho o mong le ho tloha lehlakoreng le leng la 'mele ho ea ho le leng. Ho nka mali ho batho ba bang ho ka ba thata ho feta ho ba bang.

Likotsi tse ling tse amanang le ho huloa mali li nyane, empa li ka kenyelletsa:

• Ho tsoa mali a mangata
• Ho akheha kapa ho ikutloa o le hlooho e boima
• Li-punctures tse ngata ho fumana methapo
• Hematoma (mali a bokellanang ka tlasa letlalo)
• Tšoaetso (kotsi e nyane neng kapa neng ha letlalo le robehile)

IEP - serum; Immunoglobulin electrophoresis - mali; Gamma globulin electrophoresis; Serum immunoglobulin electrophoresis; Amyloidosis - electrophoresis serum; Myeloma e ngata - serum electrophoresis; Waldenström - serum electrophoresis

• Teko ea mali

Aoyagi K, Ashihara Y, Kasahara Y. Immunoassays le immunochemistry. Ka: McPherson RA, Pincus MR, bahlophisi. Henry's Clinical Diagnosis le Tsamaiso ka Mekhoa ea Laboraro. La bo23 la ed. St Louis, MO: Elsevier; 2017: khaolo ea 44.

Kricka LJ, Park JY. Mekhoa ea ho itšireletsa mafung. Ka: Rifai N, ed. Tietz ea Buka ea Khemistri ea Kliniki le Diagnostics ea Limolek'hule. La 6th. St Louis, MO: Elsevier; 2018: khaolo ea 23.